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Quaternary Activity Characteristics and Regional Tectonic Significance of the Jiulong Fault in Jiujiang,Jiangxi Province,China

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Journal of Earth Science 2024年第4期35卷 1107-1117页

作者： Xin Qi yuyong Jiao Qinghua Li Bin Li Faculty of Engineering China University of GeosciencesWuhan430074China Wuhan Center China Geological SurveyWuhan430205China Institute of Geological Survey China University of GeosciencesWuhan430074China

Obtaining geological and landform dislocation features,as well as the measured stratigraphic activity age,provides direct evidence to evaluate fault activity,which is more difficult to do in areas with low tectonic activity,such as eastern and central China.A detailed investigation of the fault activity,trenching,drilling joint geological profile,geological survey,and chronological analysis were used to obtain the spatial geometry,fault kinematics,and activity chronology of the Jiulong *** conclusions are as follows:(1)The Jiulong fault was a fracture zone composed of four branch faults,with a width of around 30–40 m and good extendibility,while the maximum surface rupture length was 373 m.(2)The Jiulong fault has many strata dislocations,and the dislocation distance decreased from bottom to top,demonstrating synsedimentary structure characteristics,with a maximum stratigraphic dislocation distance of 18.2 m.(3)Preliminary analysis suggested the Jiulong fault as a secondary fracture of the Xiangfan-Guangji fault zone and provided evidence of the southeastward extension of the Xiangfan-Guangji fault.A preliminary hypothesis purported the Xiangfan-Guangji fault as the seismogenic fault of the Ms 5.0 magnitude earthquake in 1911.(4)According to OSL and ESR dating analyses,the upper breakpoint of the Jiulong fault cuts into the Late Pleistocene Xingang Formation(Qp3x)strata,and the latest active age of the Jiulong fault was 57.6 *** chronology analysis confirmed an active fault from the Late Pleistocene and identified a weak tectonic in Jiujiang Province,which represents the largest active fault outcrop uncovered in the area so *** study provides evidence and research materials for the evaluation of fault activity and seismic stability in this region.

关键词： active fault regional tectonic earthquakes seismic intensity tectonics

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Construction of alkyl-substituted 7-norbornenones through Diels-Alder cycloaddition of electron-deficient olefins and a cyclopentadienone derivative generated in situ

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Chinese Chemical Letters 2022年第4期33卷 2041-2043页

作者： Shanxiang Liu Jinxin wang yuyong Ma Xin Cao Wei-Dong Zhang Ang Li School of Traditional Chinese Pharmacy China Pharmaceutical UniversityNanjing 211198China State Key Laboratory of Bioorganic and Natural Products Chemistry Center for Excellence in Molecular SynthesisShanghai Institute of Organic ChemistryChinese Academy of SciencesUniversity of Chinese Academy of SciencesShanghai 200032China State Key Laboratory of Innovative Natural Medicine and Traditional Chinese Medicine Injections Jiangxi Qingfeng Pharmaceutical Co.Ltd.Ganzhou 341000China Department of Phytochemistry School of PharmacySecond Military Medical UniversityShanghai 200433China

Dimeric sesquiterpenoids possessing densely substituted 7-norbornenone/7-norbornenol motifs pose a considerable challenge for chemical synthesis. From a strategic perspective, one could envision intermolecular Diels-Alder cycloaddition as a straightforward method for assembling alkyl-substituted 7-norbornenones. However, this approach is hindered by lability of the required dienes, namely alkylsubstituted cyclopentadienones. Here we report a one-pot protocol for construction of alkyl-substituted7-norbornenones from electron-deficient olefins and a cyclopentenone derivative. DDQ was found to be an effective oxidant for generating a cyclopentadienone intermediate in situ from the enone. A series of sterically congested 7-norbornenone-containing polycyclic compounds were prepared by using this protocol.

关键词： 7-Norbornenone Alkyl-substituted cyclopentadienone Diels-Alder cycloaddition Dimeric sesquiterpenoid

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Millimeter-Wave Bat for Mapping and Quantifying Micromotions in Full Field of View

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Research 2021年第3期2021卷 847-859页

作者： yuyong Xiong Songxu Li Changzhan Gu Guang Meng Zhike Peng State Key Laboratory of Mechanical System and Vibration School of Mechanical EngineeringShanghai Jiao Tong UniversityShanghai 200240China MoE Key Lab of Design and Electromagnetic Compatibility of High Speed Electronic System and MoE Key Lab of Artificial IntelligenceAI InstituteShanghai Jiao Tong UniversityShanghai 200240China

Echolocating bats possess remarkable capability of multitarget spatial localization and micromotion sensing in a full field of view(FFOV)even in cluttered *** technologies with such capability are highly desirable for various ***,current techniques such as visual sensing and laser scanning suffer from numerous fundamental ***,we develop a bioinspired concept of millimeter-wave(mmWave)full-field micromotion sensing,creating a unique mmWave Bat(“mmWBat”),which can map and quantify tiny motions spanning macroscopic toμm length scales of full-field targets simultaneously and *** mmWBat,we show that the micromotions can be measured via the interferometric phase evolution tracking from range-angle joint dimension,integrating with full-field localization and tricky clutter *** our approach,we demonstrate the capacity to solve challenges in three disparate applications:multiperson vital sign monitoring,full-field mechanical vibration measurement,and multiple sound source localization and reconstruction(radiofrequency microphone).Our work could potentially revolutionize full-field micromotion monitoring in a wide spectrum of applications,while may inspiring novel biomimetic wireless sensing systems.

关键词： integrating locating millimeter

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调节性T细胞在前列腺癌患者外周血中表达的研究

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临床泌尿外科杂志 2021年第6期36卷 473-477页

作者：李宁董彤王于勇胡逸轩李昶灸谢玺何华东浙江大学医学院附属杭州市第一人民医院泌尿外科杭州310006 南京医科大学附属杭州医院

目的:探讨不同分期前列腺癌患者外周血中CD4^(+)CD25^(+)CD127^(low/-)调节性T细胞(Tregs)比例变化及临床意义。方法:将2018年5月—2019年11月期间杭州市第一人民医院泌尿外科收治的部分前列腺癌患者(共90例)进行分组并招募志愿者,采集... 详细信息

目的:探讨不同分期前列腺癌患者外周血中CD4^(+)CD25^(+)CD127^(low/-)调节性T细胞(Tregs)比例变化及临床意义。方法:将2018年5月—2019年11月期间杭州市第一人民医院泌尿外科收治的部分前列腺癌患者(共90例)进行分组并招募志愿者,采集外周血处理后行流式细胞术,分析前列腺癌患者与正常对照组,以及不同分级前列腺癌组CD4^(+)CD25^(+)CD127^(low/-)表达水平是否存在差异性。结果:前列腺癌患者组外周血中的CD4^(+)CD25^(+)CD127^(low/-)Tregs表达水平与对照组比较差异有统计学意义(P<0.01);随着危险分级升高CD4^(+)CD25^(+)CD127^(low/-)Tregs的表达水平有升高趋势,且不同分级间表达水平差异有统计学意义(高危组vs.中危组,P<0.05;高危组vs.低危组,P<0.001;中危组vs低危组,P<0.001)。结论:外周血中CD4^(+)CD25^(+)CD127^(low/-)Tregs在前列腺癌患者中显著增加,且与前列腺癌的发生发展密切相关,其可为前列腺癌患者早期诊断和免疫治疗提供理论基础。

关键词：前列腺癌外周血免疫治疗

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Three-dimensional numerical manifold method for heat conduction problems with a simplex integral on the boundary

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Science China(Technological Sciences) 2024年第4期67卷 1007-1022页

作者： TONG DeFu YI XiongWei TAN Fei JIAO yuyong LIANG JiaWei Faculty of Engineering China University of GeoscienceWuhan 430074China Department of Civil Engineering Monash UniversityMelbourne VIC 3800Australia Badong National Observation and Research Station of Geohazards China University of GeoscienceWuhan 430074China

The three-dimensional numerical manifold method(3D-NMM),which is based on the derivation of Galerkin's variation,is a powerful calculation tool that uses two cover *** 3D-NMM can be used to handle continue-discontinue problems and extend to THM *** this study,we extended the 3D-NMM to simulate both steady-state and transient heat conduction *** modelling was carried out using the raster methods(RSM).For the system equation,a variational method was employed to drive the discrete equations,and the crucial boundary conditions were solved using the penalty *** solve the boundary integral problem,the face integral of scalar fields and two-dimensional simplex integration were used to accurately describe the integral on polygonal *** numerical examples were used to verify the results of 3D steady-state and transient heat-conduction *** numerical results indicated that the 3D-NMM is effective for handling 3D both steadystate and transient heat conduction problems with high solution accuracy.

关键词： three-dimensional numerical manifold method transient analysis heat conduction problem Galerkin variation simplex integration

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The BEM based on conformal Duffy-distance transformation for three-dimensional elasticity problems

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Science China(Technological Sciences) 2020年第12期63卷 2575-2583页

作者： TAN Fei LIANG JiaWei JIAO yuyong ZHU Shuai LV JiaHe Faculty of Engineering China University of GeosciencesWuhan 430074China

Here,we describe the robust and efficient application of the conventional 3D BEM in solving elasticity problems. We have focused on the precise computation of weakly singular integrals. The conformal Duffy-distance transformation was employed to alleviate near singularities caused from two aspects:(1) the large aspect ratio of elements,i.e.,element shape distortions;and(2)the closeness of element boundaries to field points,i.e.,ill-shaped patches. Then,the rigid body motion method was employed to evaluate strongly singular integrals. Numerical solutions of 3D elastostatic problems demonstrated the high accuracy of the proposed method with coarse meshes and high convergence rates with mesh refinement. Compared with the Duffy transformation and original polar coordinate transformations,the proposed method is insensitive to element shapes.

关键词： singular integrals boundary element method elasticity problems conformal transformation Duffy transformation distance transformation

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Modeling Kinetics of Deformation Induced Ferrite Transformation in Fe-C-Mn Alloy

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Journal of Iron and Steel Research International 2005年第2期12卷 49-51页

作者： XUYun-bo yuyong-mei LIUXianghua wangGuo-dong NortheasternUniversity Shenyang110004China

The influence of hot deformation on the incubation period of ferrite transformation was calculated to determine the onset of deformation induced transformation. Temperature A r3d depends on deformation condition and alloying composition, and decreases with increasing carbon content. When deformation induced ferrite transformation occurs, the flow curves of dislocation density will show strong softening characteristic. Through temperature heavy deformation, ferrite transformation is enhanced and more volume fraction is obtained. The simulated results are in good agreement with the experiment ones.

关键词： dislocation density Fe-C-Mn alloy ultra-fine steel low temperature heavy deformation

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Functions of ULK1 in autophagy and non-autophagy pathways and its implications in human physiology and disease

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BIOCELL 2020年第4期44卷 535-543页

作者： LINNA TAN yuyong TAN DELIANG LIU Department of Gastroenterology the Second Xiangya HospitalChangsha410011China Research Center of Digestive Disease Central South UniversityChangsha410011China

ULK1(unc-51 like autophagy activating kinase 1),a mammalian serine/threonine kinase,is a key component of autophagy initiation complex and helps to induce all types of *** autophagy is a process in which,through the interactions of a series of autophagy-related proteins,damaged organelles or misfolded proteins are engulfed by autophagosomes and then merged with lysosomes to be ***,canonical autophagy is an important constituent part of the cellular“quality control.”Besides,accumulating evidence indicates that ULK1 exerts autophagy-independent effects in a cell-specific *** example,ULK1 facilitates neurite elongation through the regulation of endoplasmic reticulum(ER)–Golgi trafficking in neurons,stimulates phosphopentose pathway to help NADPH(nicotinamide adenine dinucleotide phosphate hydrogen)production,and acts as a duplex regulator in type I IFN(type I interferon)induced innate immune *** the importance and diversity of ULK1 in various biological processes,this review aims to present a comprehensive overview of autophagy and non-autophagy related functions of ULK1 in a variety of human physiological,pathological,and disease processes.

关键词： Ubiquitination Axonal extension Cancer Metabolism Immune response Stress

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A Sustainable Strategy for Spent Cathode Carbon Blocks Hazardous Waste Recycling Using Binary Molten Salt Thermal Treatment

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Journal of Thermal Science 2024年第3期33卷 1082-1093页

作者： LI Bin DING Yan JIAO yuyong XU Fang wang Xinyang ZHENG Fei ZOU Junpeng GAO Qiang HU Hongyun Faculty of Engineering China University of GeosciencesWuhan430074China Institute for Natural Disaster Risk Prevention and Emergency Management China University of GeosciencesWuhan430074China State Key Laboratory of Coal Combustion Huazhong University of Science and TechnologyWuhan430074China

Waste-to-Energy treatment is a promising path to environment and energy management in the *** work detailed a binary molten salt thermal treatment methodology for the detoxification of spent cathode carbon block(SCCB)waste and the recycling of carbonaceous *** thermal behavior of SCCB and SCCB blended with molten salts was *** was found that the NaCl-Na_(2)CO_(3)binary molten salts significantly contributed to reducing pyrolysis onset temperature by 334.3 K compared to that of SCCB itself(i.e.,activation energy of pyrolysis reaction was reduced from 4.24×10^(5)to 2.30×10^(5)J/mol),thus helping to lower thermal treatment energy *** the addition of binary molten salts,the residue after thermal treatment in a horizontal tube furnace experiment was separated into two *** bottom-layer residue was mainly composed of molten *** fluorine content in the form of NaF and CaF_(2)of top-layer residue was reduced significantly while the carbon content remained ***,the leaching concentration of fluoride ion was decreased from 4620 mg/L to 856 mg/*** is noted that the NaF and CaF_(2)can be removed through water-leaching and hydrothermal acid-leaching methods and thus the carbonaceous materials with a calorific value of 17.5 MJ/kg were obtained.

关键词： spent cathode carbon block hazardous solid waste detoxification binary-molten-salt thermal treatment carbon recycling pyrolysis kinetics

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cPSAD在汉族人群PSA灰区前列腺癌早期筛查中的应用研究

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医学研究杂志 2011年第11期40卷 75-78页

作者：王于勇于志坚俞蔚文廖国栋王刚王兵何翔何华东潘毓鸣郑祥毅杭州市第一人民医院泌尿外科 310006 浙江大学医学院附属第一医院泌尿外科

目的研究cPSAD在汉族人群PSA灰区前列腺癌早期筛查中的应用价值。方法 2002年1月～2010年12月收集了265例PSA水平介于4～10ng/ml并接受前列腺穿刺活检的患者,通过接收者工作特征曲线(ROC)分析法评价PSA值、f/tP-SA值、PSAD值和cPSAD值... 详细信息

目的研究cPSAD在汉族人群PSA灰区前列腺癌早期筛查中的应用价值。方法 2002年1月～2010年12月收集了265例PSA水平介于4～10ng/ml并接受前列腺穿刺活检的患者,通过接收者工作特征曲线(ROC)分析法评价PSA值、f/tP-SA值、PSAD值和cPSAD值在预测诊断前列腺癌中的敏感性和特异性,寻找敏感性和特异性较好的前列腺癌早期预测指标。结果 265例患者中,63例为前列癌患者,占23.77%。PSA、cPSA、PSAD、t/fPSA、cPSAD 5个参数的ROC曲线下面积分别为:0.603、0.706、0.865、0.800、0.875,在所有参数中,cPSAD的AUC最大,较其他参数有更高的诊断效率。cPSAD取截点为0.0970ng/ml2时可达到90%的敏感度和63.4%的特异度,取截点为0.1296ng/ml2时可达到85%的敏感度和78.7%的特异度。结论在汉族人群PSA灰区前列腺癌早期筛查诊断中,cPSAD较其他目前常用的PSA相关指标更具优势。

关键词： cPSAD 前列腺癌 PSA PSA灰区

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