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Organo-mineral complexes in soil colloids:Implications for carbon storage in saline-alkaline paddy soils from an eight-year field experiment

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Pedosphere 2024年第1期34卷 97-109页

作者： Mengmeng CHEN Shirong ZHANG Lu liU Baojian CHANG yuyi li Xiaodong DING College of Resources and Environment Qingdao Agricultural UniversityQingdao 266109China Jingke High-tech Institute of Environmental Sciences Co. LtdBeijing 100094China Institute of Agricultural Resources and Regional Planning Chinese Academy of Agricultural SciencesBeijing 100081China

The combination of organic carbon(OC) and reactive minerals is a crucial mechanism of soil carbon(C) storage, which is regulated by the formation of organo-mineral complexes on the surface of soil colloids. The effect of organic fertilizer on the storage mechanism of OC in soil colloids was studied through an 8-year field experiment, which included four treatments: i) no fertilization(control, CK), ii) only mineral N, P, and K fertilization(NPK), iii) NPK plus a low level(450 kg C ha^(-1)year^(-1)) of organic fertilization(NPKC1), and iv) NPK plus a high level(900 kg C ha^(-1)year^(-1)) of organic fertilization(NPKC2). The main results indicated that organic fertilizer addition significantly increased the content of aromatic-C, which was 158.7% and 140.0% higher in soil colloids than in bulk soil in the NPKC1 and NPKC2 treatments, respectively. X-ray photoelectron spectroscopy further demonstrated that the relative proportion of C=C group on the surface of soil colloids was increased by 20.1% and 19.1% in the NPKC1 and NPKC2 treatments, respectively,compared with the CK. In addition, compared with the NPK treatment, the content of reactive minerals(such as Fe and Al oxides) significantly increased with organic fertilization, which was positively correlated with C=C group in soil colloids. This indicates that aromatic-C may be retained by the formation of aromatic-mineral complexes with reactive minerals in soil colloids. Organic fertilization also significantly increased OC storage efficiency(OCSE), which was significantly higher in the NPKC1 treatment than in the NPKC2 treatment. Therefore, a moderate amount of organic fertilizer application is a better agronomic practice to increase OCSE and OC storage in saline-alkaline paddy soils.

关键词： aromatic-C aromatic-mineral complex organic fertilization reactive mineral soil organic carbon water-dispersible colloid

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Design and discovery of a highly potent ultralong-acting GLP-1 and glucagon co-agonist for attenuating renal fibrosis

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Acta Pharmaceutica Sinica B 2024年第3期14卷 1283-1301页

作者： Qian Zhao Jiale Dong Han liu Hui Chen Huan Yu Shuyin Ye Shuangjin Yu Yu li Longhui Qiu Nazi Song Hongjiao Xu Qi liu Zhiteng Luo yuyi li Rui Wang Guodong Chen Xianxing Jiang School of Pharmaceutical Sciences Guangdong Provincial Key Laboratory of Chiral Molecule and Drug DiscoverySun Yat-sen UniversityGuangzhou 510006China Organ Transplant Center the First Affiliated HospitalSun Yat-sen UniversityGuangzhou 510006China Zhongshan School of Medicine Sun Yat-sen UniversityGuangzhou 510006China Shenzhen Turier Biotech.Co. Ltd.Shenzhen 518118China School of life Sciences Key Laboratory of Preclinical Study for New Drugs of Gansu ProvinceSchool of Basic Medical Sciences&Research Unit of Peptide ScienceChinese Academy of Medical SciencesLanzhou UniversityLanzhou 730000China

The role of co-agonists of glucagon-like peptide-1 receptor(GLP-1R)and glucagon receptor(GCGR)in chronic kidney disease(CKD)remains unclear.Herein we found that GLP-1R and GCGR expression levels were lower in the kidneys of mice with CKD compared to healthy mice and were correlated with disease severity.Interestingly,GLP-1R or GCGR knockdown aggravated the progression of kidney injury in both diabetic db/db mice and non-diabetic mice undergoing unilateral ureteral obstruction(UUO).Based on the importance of GLP-1R and GCGR in CKD,we reported a novel monomeric peptide,1907-B,with dual-agonism on both GLP-1R and GCGR.The data confirmed that 1907-B had a longer half-life than long-acting semaglutide in rats or cynomolgus monkeys(~2-3 fold)and exhibited better therapeutic contribution to CKD than best-in-class monoagonists,semaglutide,or glucagon,in db/db mice and UUO mice.Various lock-of-function models,including selective pharmacological activation and genetic knockdown,confirmed that 1907-B’s effects on ameliorating diabetic nephropathy in db/db mice,as well as inhibiting kidney fibrosis in UUO mice,were mediated through GLP-1 and glucagon signaling.These findings highlight that 1907-B,a novel GLP-1R and GCGR co-agonist,exerts multifactorial improvement in kidney injuries and is an effective and promising therapeutic option for CKD treatment.

关键词： GLP-1 receptor Glucagon receptor Chronic kidney disease Diabetic nephropathy Kidney fibrosis Dual-agonism

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航空发动机燃烧室机匣烧穿火焰特性试验研究

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清华大学学报（自然科学版） 2024年第6期64卷 984-991页

作者：徐翔陈龙李松阳万羽翼中国民用航空局第二研究所审定中心成都610207 中国航发商用航空发动机有限责任公司先进技术部上海200241 中国民用航空局航油航化产品适航与绿色发展重点实验室成都610207 中国科学技术大学火灾科学国家重点实验室合肥230026

为研究航空发动机燃烧室机匣发生烧穿时射流火焰的温度、热流密度分布,建立机匣烧穿试验系统,采用单一变量法,研究了喷嘴孔径、油气质量比、外侧空气流速、燃烧室内部压力对射流火焰在轴向上的温度、热流密度分布的影响。结果表明:射流... 详细信息

为研究航空发动机燃烧室机匣发生烧穿时射流火焰的温度、热流密度分布,建立机匣烧穿试验系统,采用单一变量法,研究了喷嘴孔径、油气质量比、外侧空气流速、燃烧室内部压力对射流火焰在轴向上的温度、热流密度分布的影响。结果表明:射流火焰在轴向上的热流密度衰减迅速,在127~254 mm内,热流密度衰减最多,可达81%;喷嘴孔径对于火焰形态、温度、热流密度影响最大;燃烧室内部压力对火焰温度影响可达675℃/MPa;外侧空气流速主要影响火焰轴向254~508 mm区间温度分布;油气质量比对火焰轴向温度影响达18.6%。航空发动机设计时应当考虑在燃烧室机匣薄弱点法线方向外侧254 mm范围内设置挡火板,以防止可能出现的机匣烧穿带来的危害。

关键词：机匣烧穿射流火温度热流密度火焰

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人工智能时代饲料企业社会责任的履行及优化路径

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中国饲料 2024年第4期 165-168页

作者：李雨益杨国强西南政法大学经济法学院重庆401120

随着人工智能技术的快速发展和应用,各产业都迎来了巨大变革,饲料企业也不例外,正面临着前所未有的挑战和机遇。在人工智能时代,饲料企业如何履行社会责任以顺应时代潮流,进而实现可持续发展是值得关注的议题。文章首先分析了人工智能... 详细信息

随着人工智能技术的快速发展和应用,各产业都迎来了巨大变革,饲料企业也不例外,正面临着前所未有的挑战和机遇。在人工智能时代,饲料企业如何履行社会责任以顺应时代潮流,进而实现可持续发展是值得关注的议题。文章首先分析了人工智能时代饲料企业在生产研发环节和销售管理环节存在的社会责任履行困境;其次,针对上述困境,根据人工智能时代饲料企业的特点提出相应的优化路径;最后,希望通过以上措施促进饲料企业在人工智能时代获得发展机遇的同时履行社会责任。

关键词：饲料企业企业社会责任人工智能可持续发展

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Express and sensitive detection of multiple miRNAs via DNA cascade reactors functionalized photonic crystal array

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Science China Chemistry 2020年第5期63卷 731-740页

作者： Yingfei Wang yuyi li Yue Zhang Kewei Ren Huangxian Ju Ying liu State Key Laboratory of Analytical Chemistry for life Science School of Chemistry and Chemical EngineeringNanjing UniversityNanjing 210023China Chemistry and Biomedicine Innovation Center Nanjing UniversityNanjing 210023China Department of Chemistry University of MassachusettsAmherstMassachusetts 01003USA

Array based detection techniques with fluorescence signal reading is a powerful tool for multiple targets analysis. However,when applied fluorescence array for micro RNA detection, time-consuming multi-steps surface signal amplification is usually required due to the low abundance of micro RNA in total RNA expressions, which impairs detection efficiency and limits its application in point of care test(POCT) manner. Herein, DNA cascade reactors(DCRs) functionalized photonic crystal(PC)array was fabricated for express and sensitive detections of mi RNA-21 and mi RNA-155. DCRs were assembled by interval conjugation of self-quenched hairpin DNA probes to single strand DNA nanowire synthesized by rolling circle amplification,which generated cascade DNA hybridization reactions in response to target mi RNAwith instant fluorescence recovery signal. PC array patterns with multi-structure colors further amplified fluorescence with their respective photonic bandgaps(PBGs)matching with the emission peaks of fluorescence molecules labelled on DCRs. The as-prepared DCRs functionalized PC array demonstrated express and sensitive simultaneous detections of mi RNA-21 and mi RNA-155 with hundreds f M detection limits only in 15 min, and was successfully applied in fast quantifications of low abundance mi RNAs from cell lysates and spiked mi RNAs from human serum, which would hold great potential for disease diagnosis and therapeutic effect monitoring with a POCT manner.

关键词： micro RNA detection photonic crystal array DNA cascade reactors fluorescence amplification express detection

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非相干拉曼显微技术及其生物医学应用(特邀)

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激光与光电子学进展 2024年第6期61卷 153-174页

作者：黎钰怡干越牛犇黄静詹求强华南师范大学华南先进光电子研究院广东广州510006

拉曼技术具有非侵入、分子指纹、不受水干扰、制样简单、光谱分辨率高等优点,在很多领域都是一种广受欢迎的研究工具。尤其在生物医学领域,拉曼技术不仅可以本征地捕捉正常生理或病理所携带的不同化学信息,而且该技术适用于检测各种常... 详细信息

拉曼技术具有非侵入、分子指纹、不受水干扰、制样简单、光谱分辨率高等优点,在很多领域都是一种广受欢迎的研究工具。尤其在生物医学领域,拉曼技术不仅可以本征地捕捉正常生理或病理所携带的不同化学信息,而且该技术适用于检测各种常见的生物和临床样品(包括细胞、组织、体液和微生物等),目前很多课题组的研究结果都表明拉曼技术在生物医学领域具有巨大的应用前景。本文首先介绍自发拉曼散射和表面增强拉曼散射的基本工作机理,接着介绍分析处理拉曼数据(光谱和图像)的步骤和算法,然后简单总结了近年来非相干拉曼显微技术在生物医学上的研究成果,最后指出拉曼技术目前面临的挑战并展望了其未来可能的发展方向。

关键词：自发拉曼表面增强拉曼数据分析生物医学应用

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An Overview of the Causes and Countermeasures of Academic Misconduct in Colleges and Universities

An Overview of the Causes and Countermeasures of Academic Mi...

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作者： Yanni li yuyi li The Experimental Training Base of College of Information and Communication National University of Defense Technology College of Information and Communication National University of Defense Technology

The research on academic misconduct is conducive to the correct guidance and reasonable management and control of the current academic research behaviors that frequently resort to fraud and seek quick success, so as to create a positive and clean scientific research environment. The relevant domestic studies are carefully sorted out to find out the existing deficiencies, which will provide references for the follow-up research and ultimately facilitate the smooth development of the work at the level of system and practice.

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磁改性污泥基生物炭对猪粪堆肥及土霉素降解的影响

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环境科学学报 2024年第4期44卷 187-197页

作者：李钰辉卓桂华沈凯茜李海霞景乐陈琬甄广印郑育毅福建师范大学环境与资源学院、碳中和现代产业学院福建省污染控制与资源循环利用重点实验室福州350007 城市废物资源化技术与管理福建省高校工程研究中心福州350007 福建省环境科学研究院福州350013 福建省环境工程重点实验室福州350025 漳州台商投资区招商服务中心漳州363107 华东师范大学生态与环境科学学院上海200241

为探究磁改性污泥基生物炭(MMSB)对猪粪堆肥过程和土霉素(OTC)降解的影响,以猪粪和木屑为原料,将0.1 mol·L^(-1)和0.25 mol·L^(-1)浓度Fe^(2+)/Fe^(3+)混合溶液改性的MMSB-0.1和MMSB-0.25以10%的质量比(猪粪干基)分别添加到猪粪中进... 详细信息

为探究磁改性污泥基生物炭(MMSB)对猪粪堆肥过程和土霉素(OTC)降解的影响,以猪粪和木屑为原料,将0.1 mol·L^(-1)和0.25 mol·L^(-1)浓度Fe^(2+)/Fe^(3+)混合溶液改性的MMSB-0.1和MMSB-0.25以10%的质量比(猪粪干基)分别添加到猪粪中进行批式堆肥试验.结果表明,与CK相比,MMSB处理均延长堆肥高温期(1~3 d),提高峰值温度(1.0~3.3℃),加速含水率(MC)下降(5.14%~7.00%).由于堆体的改善促进了腐殖质的进程,MMSB-0.1组和MMSB-0.25组的胡敏酸(HA)分别提高18.16%、10.76%,胡富比分别提高57.17%、37.75%,低剂量磁改性促进效果更佳.另一方面,MMSB的添加降低了OTC的半衰期,但由于MMSB负载了Fe_(3)O_(4),对OTC吸附性增强,导致MMSB实验组的OTC最终降解率均低于CK,且磁改性浓度高低对此影响差别不大.Pearson相关性分析和冗余分析(RDA)表明,堆肥腐熟度和OTC降解主要受MC、温度和可溶性有机碳(DOC)的影响.MMSB有利于在猪粪堆肥过程中调节理化性质、提高腐熟度以及加速OTC降解,低剂量磁改性的MMSB-0.1尤甚.本研究可为磁改性生物炭应用于改善猪粪堆肥提供基础依据.

关键词：猪粪堆肥磁改性污泥基生物炭腐殖质土霉素降解

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The Feasibility Study of Blended English Teaching Based on SPOC

The Feasibility Study of Blended English Teaching Based on S...

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作者： Meng li Mei Song Xinshe Qi yuyi li College of Information and Communication National University of Defense Technology

Since "SPOC" was introduced in 2013 by the American University of California, it had become a totally new teaching mode combining information era with new teaching resources. The online "small private online course" has brought a revolution on the content and form as well. The paper, through the teaching practice of military English in college of information and communication for one semester, applies a new "SPOC" teaching mode of English and explores a further combination of SPOC plus mobile media intelligent teaching tools. It is aiming to provide a reference for the later English teaching SPOC mode in military academies.

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Passive robust control for uncertain Hamiltonian systems by using operator theory

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CAAI Transactions on Intelligence Technology 2022年第4期7卷 594-605页

作者： Ni Bu yuyi Zhang Xiaoyong li Wei Chen Changan Jiang College of Automation and Electronic Engineering Qingdao University of Science and TechnologyQingdaoChina Department of Robotics Osaka Institute of TechnologyOsakaJapan

In this study,the passivity-based robust control and tracking for Hamiltonian systems with unknown perturbations by using the operator-based robust right coprime factorisation method is concerned.For the system with unknown perturbations,a design scheme is proposed to guarantee the uncertain non-linear systems to be robustly stable while the equivalent non-linear systems is passive,meanwhile the asymptotic tracking property of the plant output is discussed.Moreover,the design scheme can be also used into the general Hamiltonian systems while the simulation is used to further demonstrate the effectiveness of the proposed method.

关键词： Hamiltonian systems robust right coprime factorisation storage function

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