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AN IMPROVED JONES-NELSON NONLINEAR MATERIAL MODEL AND RUBBER COMPOSITE LAMINA ANALYSIS

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Acta Mechanica Solida Sinica 1998年第1期11卷 28-36页

作者： Tan Huifeng liu yuyan Du Xingwen Harbin Inst Technol Composite Mat Res Lab Harbin 150001 Peoples R China

A Jones-Nelson model has been applied to depict nonlinearstress-strain relations of composite laminae, where mechanicalproperties were expressed by strain energy density. The nonlin- earmaterial matrix is only a function of the strain energy density. Thena material model could be conveniently applied under complex stresscondition. In this paper, by introducing large displacementstress-strain measurement and varying-Poisson's ratio idea, animproved Jones-Nelson material model is presented, where theexpanding problem of material properties and convergence problems areover- come.

关键词： Jones-Nelson model finite deformation

A phase separation-fortified bi-specific adaptor for conditional tumor killing

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Science China(Life Sciences) 2024年第7期67卷 1385-1397页

作者： yuyan liu Yuting Zhu Weifan Xu Pilong Li State Key Laboratory of Membrane Biology Frontier Research Center for Biological StructureTsinghua University-Peking University Joint Center for Life SciencesSchool of Life SciencesTsinghua UniversityBeijing 100084China

A common approach in therapeutic protein development involves employing synthetic ligands with multivalency,enabling sophisticated control of signal *** the emerging concept of liquid-liquid phase separation(LLPS)and its ability to organize cell surface receptors into functional compartments,we herein have designed modular ligands with phase-separation modalities to engineer programmable interreceptor communications and precise control of signal pathways,thus inducing the rapid,potent,and specific apoptosis of tumor *** their simplicity,these“triggers”,named phase-separated Tumor Killers(hereafter referred to as psTK),are sufficient to yield interreceptor clustering of death receptors(represented by DR5)and tumor-associated receptors,with notable features:LLPSmediated robust high-order organization,well-choreographed conditional activation,and broad-spectrum capacity to potently induce apoptosis in tumor *** development of novel therapeutic proteins with phase-separation modalities showcases the power of spatially reorganizing signal *** approach facilitates the diversification of cell fate and holds promising potential for targeted therapies against challenging tumors.

关键词： phase separation therapeutic proteins receptor-ligand interactions DR5 tumor apoptosis

Ultrathin 2D Metal–Organic Framework Nanosheets In situ Interpenetrated by Functional CNTs for Hybrid Energy Storage Device

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Nano-Micro Letters 2020年第4期12卷 1-13页

作者： Feitian Ran Xueqing Xu Duo Pan yuyan liu Yongping Bai Lu Shao MIIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage State Key Laboratory of Urban Water Resource and Environment(SKLUWRE)School of Chemistry and Chemical EngineeringHarbin Institute of TechnologyHarbin 150001People’s Republic of China Key Laboratory of Materials Processing and Mold(Zhengzhou University) Ministry of EducationNational Engineering Research Center for Advanced Polymer Processing TechnologyZhengzhou UniversityZhengzhou 450002People’s Republic of China

The controllable construction of two-dimensional(2D)metal–organic framework(MOF)nanosheets with favorable electrochemical performances is greatly challenging for energy ***,we design an in situ induced growth strategy to construct the ultrathin carboxylated carbon nanotubes(C-CNTs)interpenetrated nickel MOF(Ni-MOF/C-CNTs)*** deliberate thickness and specific surface area of novel 2D hybrid nanosheets can be effectively tuned via finely controlling C-CNTs *** to the unique microstructure,the integrated 2D hybrid nanosheets are endowed with plentiful electroactive sites to promote the electrochemical performances *** prepared Ni-MOF/C-CNTs nanosheets exhibit superior specific capacity of 680 C g^−1 at 1 A g^−1 and good capacity *** assembled hybrid device demonstrated the maximum energy density of 44.4 Wh kg^−1 at a power density of 440 W kg^−*** novel strategy to construct ultrathin 2D MOF with unique properties can be extended to synthesize various MOF-based functional materials for diverse applications.

关键词： Metal–organic frameworks Carbon nanotubes Ultrathin 2D nanosheets Hybrid supercapacitor

Microstructure and magnetic fabric in the Shuanghe pluton:A synkinematic granite in Eastern Dabie Mountains,China

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Science China Earth Sciences 2004年第10期47卷 912-919页

作者： YANG Kunguang liu Qiang liu yuyan MA Changqian XU Yajun YANG Kuifeng Faculty of Earth Sciences China University of Geosciences Wuhan 430074 China Faculty of Earth Sciences China University of Geosciences Wuhan 430074 China Faculty of Earth Sciences China University of Geosciences Wuhan 430074 China Faculty of Earth Sciences China University of Geosciences Wuhan 430074 China Faculty of Earth Sciences China University of Geosciences Wuhan 430074 China Faculty of Earth Sciences China University of Geosciences Wuhan 430074 China

Strain analyses for the Shuanghe pluton show that the main strain planes suffered distinct deformation. The main strain value (XZ) is up to 1.59–2.18, and the value of Flinn index (K) ranges from 0.11 to 0.82. Anisotropy of magnetic susceptibility (AMS) measurements reveal that the orientations of the magnetic foliation and lineation gently dip SE, consistent with the macroscopic foliation of the pluton. The value of anisotropy degree (P) ranges from 1.109 to 1.639, and the shape parameter (T) from 0.079 to 0.534. These studies prove that the pluton was deformed under strong compression. Quartz c-axis textures, defined by monoclinic or triclinic asymmetry, usually developed the high maxima paralleling the b-axis, which is defined by the prismatic slip (1010) under the high temperature. These fabrics are quite different from those developed in the high-ultrahigh pressure rocks (UHP) which were captured in the pluton or country rocks. It is concluded that the Shuanghe pluton emplaced under regional compression slightly after the formation of UHP, and it is characterized by synkinematic granitic deformation.

关键词： strain analysis, anisotropy of magnetic susceptibility (AMS), quartz c-axis fabric, synkinematic granite,Dabie Mountains.

Space debris environment engineering model 2019:Algorithms improvement and comparison with ORDEM 3.1 and MASTER-8

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Chinese Journal of Aeronautics 2024年第5期37卷 392-409页

作者： yuyan liu Runqiang CHI Baojun PANG HU Diqi Wuxiong CAO Dongfang WANG School of Astronautics Harbin Institute of TechnologyHarbin 150001China College of Safety Science&Engineering Civil Aviation University of ChinaTianjin 300300China

As an essential tool for realistic description of the current or future debris environment,the Space Debris Environment Engineering Model(SDEEM)has been developed to provide support for risk assessment of *** contrast with SDEEM2015,SDEEM2019,the latest version,extends the orbital range from the Low Earth Orbit(LEO)to Geosynchronous Orbit(GEO)for the years *** this paper,improved modeling algorithms used by SDEEM2019 in propagating simulation,spatial density distribution,and spacecraft flux evaluation are *** debris fluxes of SDEEM2019 are compared with those of three typical models,i.e.,SDEEM2015,Orbital Debris Engineering Model 3.1(ORDEM 3.1),and Meteoroid and Space Debris Terrestrial Environment Reference(MASTER-8),in terms of two assessment *** orbital cases,including the Geostationary Transfer Orbit(GTO),Sun-Synchronous Orbit(SSO)and International Space Station(ISS)orbit,are selected for the spacecraft assessment mode,and the LEO region is selected for the spatial density assessment *** analysis indicates that compared with previous algorithms,the variable step-size orbital propagating algorithm based on semi-major axis control is more precise,the spatial density algorithm based on the second zonal harmonic of the non-spherical Earth gravity(J_(2))is more applicable,and the result of the position-centered spacecraft flux algorithm is more *** comparison shows that SDEEM2019 and MASTER-8 have consistent trends due to similar modeling processes,while the differences between SDEEM2019 and ORDEM 3.1 are mainly caused by different modeling approaches for uncatalogued debris.

关键词： SDEEM2019 Space debris propagating algorithm Spatial density algorithm ORDEM 3.1 MASTER-8

Pulse width effect on the dissociation probability of CH_4^+ in the intense femtosecond laser field

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Chinese Science Bulletin 2006年第10期51卷 1269-1272页

作者： WANG Cao SONG Di liu yuyan KONG Fan'ao Institute of Chemistry Chinese Academy of Sciences Beijing 100080 China Wuhan Institute of Physics and Mathematics Chinese Academy of Sciences Wuhan 430071 China Graduate School of Chinese Academy of Sciences Beijing 100049 China

The laser pulse width effect on the dis- sociation probability of CH4+ irradiated by an ultrafast laser has been investigated experimentally and theoretically. The femtosecond laser at 800 nm with an intensity of 8.0 × 1013 W/cm2 was used. The ob- served relative yield of the primary fragment ion CH3+ increases with increasing pulse width and tends to saturate when the pulse width is longer than 120 fs. The field-assisted dissociation (FAD) model and quasi-classical trajectory (QCT) calculation were ap- plied to predicting the dissociation probability of CH4+. The calculated probability is corrected with the mo- lecular orientation effect and the spatial distribution of laser intensity. The modified results show that the dissociation requires at least 23 fs and saturates with long pulse widths (≥100 fs). The result is ap- proximately consistent with the experimental observa- tion.

关键词：毫微微秒激光器强激光区甲烷离解概率激光脉冲宽度

A photocatalytic radical relay reaction of 2-methylthiolated phenylalkynones and potassium metabisulfite

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Organic Chemistry Frontiers 2022年第2期9卷 450-455页

作者： yuyan liu Xinyi Zhang Jiajing Lv Chao Zhang Xiaotong Chang Shengqing Ye Jie Wu School of Pharmaceutical and Materials Engineering&Institute for Advanced Studies Taizhou University1139 Shifu AvenueZhejiang 318000China State Key Laboratory of Organometallic Chemistry Shanghai Institute of Organic ChemistryChinese Academy of Sciences345 Lingling RoadShanghai 200032China School of Chemistry and Chemical Engineering Henan Normal UniversityXinxiang 453007China

The generation of methylsufonyl-containing thioflavones through a radical relay reaction of methylthiolated phenylalkynones and potassium metabisulfite in the presence of a catalytic amount of sodium methylsulfinate as an initiator under photoinduced conditions is *** photocatalytic reaction proceeds smoothly with good functional group tolerance under visible light *** mechanistic investigations indicate that this reaction occurs through a radical relay pathway.

关键词： radical potassium smoothly

On-line Monitoring of Epoxy Resin Exposed to Acid Solution

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Journal of Materials Science & Technology 2006年第3期22卷 414-418页

作者： yuyan liu M.Ku bouchi H.Semboku ya K. Tsuda T. Tomiyama Harbin Institute of Technology Harbin 150001 China Tokyo Institute of Technology Tokyo Japan Public Works Research Institute Ibaraki Japan

In this study, a new on-line health monitoring technology for the determination of the penetration of environment solution into epoxy resin was pursued. A corrosion sensor including plastic optical fiber and pH indicator was fabricated. The color-change layer of this sensor appeared after immersion in sulfuric acid solution, which could be examined by using optical fiber and spectrophotometer. The results showed that the penetration of sulfuric acid was detected by adding bromophenol blue （BPB） in the corrosion sensor. This system could be applied to on-line health monitoring of chemical equipment structures.

关键词： Epoxy resin Optical fiber Corrosion monitor

Genome-wide identification of functional enhancers and their potential roles in pig breeding

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Journal of Animal Science and Biotechnology 2022年第6期13卷 1690-1702页

作者： Yinqiao Wu Yuedong Zhang Hang liu Yun Gao yuyan liu Ling Chen Lu liu David M.Irwin Chunhui Hou Zhongyin Zhou Yaping Zhang State Key Laboratory of Genetic Resources and Evolution and Yunnan Laboratory of Molecular Biology of Domestic AnimalsKunming Institute of ZoologyChinese Academy of SciencesKunming 650223YunnanChina Kunming College of Life Science University of Chinese Academy of SciencesKunming 650204YunnanChina State Key Laboratory for Conservation and Utilization of Bio-resource in Yunnan Yunnan UniversityKunming 650091YunnanChina School of Life Science Yunnan UniversityKunming 650091YunnanChina Institute of Physical Science and Information Technology Anhui UniversityHefei 230601AnhuiChina Department of Laboratory Medicine and Pathobiology University of TorontoTorontoCanada Department of Biology School of Life SciencesSouthern University of Science and TechnologyShenzhen 518055China Center for Excellence in Animal Evolution and Genetics Chinese Academy of SciencesKunming 650223YunnanChina

Background:The pig is an economically important livestock species and is a widely applied large animal model in medical *** are critical regulatory elements that have fundamental functions in evolution,development and ***-wide quantification of functional enhancers in the pig is ***:We performed self-transcribing active regulatory region sequencing(STARR-seq)in the porcine kidney epithelial PK15 and testicular ST cell lines,and reliably identified 2576 functional *** of these enhancers were located in repetitive sequences and were enriched within silent and lowly expressed *** poorly overlapped with chromatin accessibility regions and were highly enriched in chromatin with the repressive histone modification H3K9me3,which is different from predicted pig enhancers detected using ChIP-seq for H3K27ac or/and H3K4me1 modified *** suggests that most pig enhancers identified with STARR-seq are endogenously repressed at the chromatin level and may function during cell type-specific development or at specific developmental ***,the PPP3CA gene is associated with the loin muscle area trait and the QKI gene is associated with alkaline phosphatase activity that may be regulated by distal functional ***:In summary,we generated the first functional enhancer map in PK15 and ST cells for the pig genome and highlight its potential roles in pig breeding.

关键词： Breeding Functional enhancers Pig STARR-seq