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Journal of Energy Chemistry 2021年第6期30卷 587-592,I0014页

作者： yuxuan wei Yanlong Lv Beidou Guo Jianru Gong Chinese Academy of Sciences(CAS)Center for Excellence in Nanoscience CAS Key Laboratory for Nanosystem and Hierarchical FabricationNational Center for Nanoscience and TechnologyBeijing 100190China University of CAS Beijing 100049China

The hierarchical structure of molybdenum disulfide(MoS2)nanosheet arrays stemmed from nickelcobalt layered double hydroxide(NiCo-LDH)/carbon cloth was prepared by growing the MoS_(2) nanosheet arrays onto the NiCo-LDH template which was pre-deposited onto the carbon cloth *** this electrode configuration,carbon cloth is the three dimensional and conductive skeleton;NiCo-LDH nanosheets,as the template,ensure the oriented growth of MoS2 nanosheet ***,more MoS_(2) active sites are exposed and the catalyst exhibits good hydrogen evolution reaction activity.

关键词： Hydrogen evolution reaction catalysts Hierarchical structure Molybdenum disulfide Nickel-cobalt layered double hydroxide

Shape Memory Polymer Composite Booms with Applications in Reel-Type Solar Arrays

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Chinese Journal of Mechanical Engineering 2023年第3期36卷 326-338页

作者： Hong Xiao Sijie Wu Dongdong Xie Hongwei Guo Li Ma yuxuan wei Rongqiang Liu State Key Laboratory of Robotics and System Harbin Institute of TechnologyHarbin 150006China Yinhe Hangtian Internet Technology Co. Ltd.Beijing 100192China China Academy of Space Technology Beijing 100098China

Solar arrays are the primary energy source for *** traditional rigid solar arrays improve power supply,the quality increases ***,it is difficult to satisfy the requirements of high-power and low-cost space *** this study,a shape-memory polymer composite(SMPC)boom was designed,fabricated,and characterized for flexible reel-type solar *** SMPC boom was fabricated from a smart material,a shape-memory polymer composite,whose mechanical properties were ***,a mathematical model of the bending stiffness of the SMPC boom was developed,and the bending and buckling behaviors of the boom were further analyzed using the ABAQUS *** SMPC boom was fabricated to demonstrate its shape memory characteristics,and the driving force of the booms with varying geometric parameters was *** also designed and manufactured a reel-type solar array based on an SMPC boom and verified its self-deployment *** results indicated that the SMPC boom can be used as a deployable unit to roll out flexible solar arrays.

关键词： Shape memory polymer composite Reel-type solar array Deployable boom Bending behavior

Autologous osteoperiosteal transplantation for cystic osteochondral lesions of the talus:Bone reconstruction is essential

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Chinese Journal of Traumatology 2024年第6期27卷 395-402页

作者： yuxuan wei Zhuhong Chen Nian Sun Zhu Tang Hao Guo Canjun Zeng Department of Foot and Ankle Surgery Center for Orthopaedic SurgeryThe Third Affiliated Hospital of Southern Medical UniversityGuangzhou510630China Department of Orthopaedic Surgery Central People's Hospital of ZhanjiangZhanjiang524045Guangdong ProvinceChina

Purpose:Autologous osteoperiosteal transplantation(AOPT)is one of the most feasible and effective techniques for cystic osteochondral lesions of the talus(OLT).However,few reports have been reported about the process of graft-host bone healing and bone articular surface reconstruction,which help us to further understand the actual situation of bone healing and modify surgical ***:The case series study retrospectively evaluated 33 osteochondral lesions in 30 patients undertaking AOPT for OLT with subchondral cysts from December 2016 to October *** to CT observation,we used 4 variables to describe the bony articular repair,including the integration of the articular surface,the height of the bone filling,the status of bone union,and the appearance of bone resorption or cystic *** also analyzed the demographic data and clinical *** statistics were used for demographic and clinical *** distributed data were presented as mean±SD,and non-normally distributed data were presented as median(Q1,Q3).Associations between these variables and the primary clinical outcomes were examined usingt-test or one-way ANOVA test for continuous ***:The patients’mean age was(41.7±14.0)years old and the mean follow-up time was(29.6±17.8)*** chondral lesion size was(14.3±4.1)*** cyst depth was(10.9±3.7)*** improvements were observed in functional outcomes(according to the numeric rating scale for pain when walking and the American orthopedic foot and ankle society score)between the preoperative and latest follow-up evaluations,from 4.2±2.1 to 2.2±2.0(p1 mm"was found in 27 grafts(81.8%),a

关键词： Osteochondral lesion Cystic defects Talus Autograft Iliac Bony reconstruction

Metal-coordinated oxidative stress amplifier to suppress tumor growth combined with M2 macrophage elimination

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Chinese Chemical Letters 2024年第12期35卷 220-225页

作者： Chuyu Huang Zhishan Liu Linping Zhao Zuxiao Chen Rongrong Zheng Xiaona Rao yuxuan wei Xin Chen Shiying Li The Fifth Affiliated Hospital Guangdong Provincial Key Laboratory of Molecular Target & Clinical Pharmacologythe NMPA and State Key Laboratory of Respiratory Diseasethe School of Pharmaceutical SciencesGuangzhou Medical University Department of Pulmonary and Critical Care Medicine Zhujiang HospitalSouthern Medical University

The anti-oxidative characteristic and immunosuppressive microenvironment contribute to a high resistance of tumor to many treatments. In this work, a glutathione(GSH)-responsive metal-coordinated oxidative stress amplifier(designated as Cu PA) is fabricated to suppress tumor growth through elevating the cellular level of reactive oxygen species(ROS) and eliminating M2 macrophages. Among which,cooper ion(Cu2+) is capable of coordinating with thioredoxin(Trx) inhibitor of PX-12 and signal transducer and activator of transcription 6(STAT6) inhibitor of AS1517499 with the assistance of distearoyl phosphoethanolamine-PEG2000(DSPE-PEG2000), which can extensively increase the stability to enhance drug delivery in vitro and in vivo. Furthermore, CuPA can upregulate intracellular ROS to cause tumor cell death through restraining Trx and degrading GSH. Also, Cu PA-mediated STAT6 inhibition results in the elimination of M2 macrophage to reverse the immunosuppressive tumor microenvironment. Finally,the elevated oxidative stress and increased immune activation amplify the synergistic antitumor effect without causing obvious side effect. This work provides a new sight for synergistic tumor suppression through chemo-immunotherapy in consideration of the complex resistant tumor microenvironment.

关键词： Oxidative stress M2 macrophage Metal coordination Chemotherapy GSH degradation

Zebrafish Foxc1a controls ventricular chamber maturation by directly regulating wwtr1 and nkx2.5 expression

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Journal of Genetics and Genomics 2022年第6期49卷 559-568页

作者： Luqingqing He Qinxin Zhang Dongya Jiang Yunfeng Zhang yuxuan wei Yuxi Yang Nan Li Shuang Wang Yunyun Yue Qingshun Zhao Model Animal Research Center Medical SchoolNanjing UniversityNanjingJiangsu 210061China Department of Prenatal Diagnosis Obstetrics and Gynecology Hospital Affiliated to Nanjing Medical UniversityNanjing Maternity and Child Health Care HospitalNanjingJiangsu 210004China School of Traditional Chinese Pharmacy China Pharmaceutical UniversityNanjingJiangsu 210009China

Chamber maturation is a significant process in cardiac development. Disorders of this crucial process lead to a range of congenital heart defects. Foxc1a is a critical transcription factor reported to regulate the specification of cardiac progenitor cells. However, little is known about the role of Foxc1a in modulating chamber maturation. Previously, we reported that foxc1a-null zebrafish embryos exhibit disrupted heart structures and functions. In this study, we observe that ventricle structure and cardiomyocyte proliferation are abolished during chamber maturation in foxc1a-null zebrafish embryos. To observe the endogenous localization of Foxc1a in the hearts of living embryos, we insert eyfp at the foxc1a genomic locus using TALEN. Analysis of the knockin zebrafish show that foxc1a is widely expressed in ventricular cardiomyocytes during chamber development. Cardiac RNA sequencing analysis reveals the downregulated expression of the Hippo signaling effector wwtr1. Dual-luciferase and chromatin immunoprecipitation assays reveal that Foxc1a can bind directly to three sites in the wwtr1 promoter region. Furthermore, wwtr1m RNA overexpression is sufficient to reverse the ventricle defects during chamber maturation. Conditional overexpression of nkx2.5 also partially rescues the ventricular defects during chamber development. These findings demonstrate that wwtr1 and nkx2.5 are direct targets of Foxc1a during ventricular chamber maturation.

关键词： Zebrafish Foxc1a Cardiac ventricular development wwtr1 nkx2.5

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一种基于神经网络的Hash函数算法研究

计算机工程与应用 2006年第14期42卷 72-75页

作者：韦玉轩韦鹏程广西建设职业技术学院南宁530003 重庆教育学院计算机与现代教育技术系重庆400067

如何设计高效、安全的带秘密密钥的单向函数一直是现代密码学研究中的一个热点。首先用神经网络来训练一维非线性分段映射产生混沌序列,并利用该模型产生的非线性序列构造带秘密密钥的Hash函数,该算法的优点之一是神经网络隐式混沌映射... 详细信息

如何设计高效、安全的带秘密密钥的单向函数一直是现代密码学研究中的一个热点。首先用神经网络来训练一维非线性分段映射产生混沌序列,并利用该模型产生的非线性序列构造带秘密密钥的Hash函数,该算法的优点之一是神经网络隐式混沌映射关系使直接获取映射关系变得困难,实验结果表明,这种算法具有对初值有高度敏感性、很好的单向性、弱碰撞性,较基于单一混沌映射的Hash函数具有更强的保密性能,且实现简单。

关键词：神经网络 Hash函数混沌分段非线性映射

Probing Interface of Perovskite Oxide Using Surface-Specific Terahertz Spectroscopy

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Ultrafast Science 2023年第6期3卷 39-46页

作者： Yudan Su Jiaming Le Junying Ma Long Cheng yuxuan wei Xiaofang Zhai Chuanshan Tian Department of Physics State Key Laboratory of Surface Physics and Key Laboratory of Micro-and Nano-Photonic Structure(MOE)Fudan UniversityShanghai 200433China Department of Physics University of CaliforniaBerkeleyBerkeleyCA 94720USA School of Physical Science and Technology ShanghaiTech University Shanghai 201210China

The surface/interface species in perovskite oxides play essential roles in many novel emergent physical phenomena and chemical *** low eigen-energies in the terahertz region,such species at buried interfaces remain poorly understood due to the lack of feasible surface-specific spectroscopic probes to resolve the ***,we show that polarized phonons and two-dimensional electron gas at the interface can be characterized using surface-specific nonlinear optical spectroscopy in the terahertz *** technique uses intra-pulse difference frequency mixing process,which is allowed only at the surface/interface of a centrosymmetric *** sensitivity can be achieved using the state-of-the-art detection scheme for the terahertz emission from the surface/*** symmetry analysis and proper polarization selection,background-free Drude-like nonlinear response from the two-dimensional electron gas emerging at the LaAlO3/SrTiO3 or Al2O3/SrTiO3 interface was successfully *** surface/interface potential,which is a key parameter for SrTiO3-based interface superconductivity and photocatalysis,can now be determined optically in a nonvacuum environment via quantitative analysis on the phonon spectrum that was polarized by the surface field in the interfacial *** interfacial species with resonant frequencies in the THz region revealed by our method provide more insights into the understanding of physical properties of complex oxides.

关键词： interface polarized interfacial

Multiband camouflage design with thermal management

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Photonics Research 2023年第5期11卷 839-851页

作者： LEHONG HUANG HAOCHUAN LI ZHIGUO LI WENBO ZHANG CAIWEN MA CHUNMIN ZHANG yuxuan wei LIANG ZHOU XUN LI ZHIYUAN CHENG XIAOHUI GUO SHIPING GUO Xi’an Institute of Optics and Precision Mechanics Chinese Academy of SciencesXi’an 710119China School of Physics Xi’an Jiaotong UniversityXi’an 710049China University of Chinese Academy of Sciences Beijing 100049China Key Laboratory of Space Precision Measurement Technology Chinese Academy of SciencesXi’an 710119China

Although the effective“stealth”of space vehicles is important,current camouflage designs are inadequate in meeting all application ***,a multilayer wavelength-selective emitter is *** can realize visible light and dual-band mid-infrared camouflage with thermal control management in two application scenarios,with better effect and stronger radiation cooling capability,which can significantly improve the stealth and survivability of space vehicles in different *** selective emitter demonstrated in this paper has the advantages of simple structure,scalability,and ease of large-area fabrication,and has made a major breakthrough in driving multiband stealth technology from simulation research to physical verification and even practical application.

关键词： breakthrough driving management

骨骼Rosai-Dorfman病的诊疗进展

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中国癌症杂志 2019年第3期29卷 229-232页

作者：卫愉轩董扬上海交通大学附属第六人民医院骨科上海200233

Rosai-Dorfman病,又称窦组织细胞增生伴巨大淋巴结病,是一种罕见的组织细胞病,通常表现为青少年的无痛性双侧颈部淋巴结肿大。Rosai-Dorfman病发病累及骨骼者不到10%,并且多达75%的骨骼Rosai-Dorfman病患者同时存在软组织病灶。颅骨、... 详细信息

Rosai-Dorfman病,又称窦组织细胞增生伴巨大淋巴结病,是一种罕见的组织细胞病,通常表现为青少年的无痛性双侧颈部淋巴结肿大。Rosai-Dorfman病发病累及骨骼者不到10%,并且多达75%的骨骼Rosai-Dorfman病患者同时存在软组织病灶。颅骨、颌面骨和胫骨是骨骼Rosai-Dorfman病最常见的发病部位。该病临床表现缺乏特异性,诊断主要依靠常规病理学和免疫组织化学染色检查。临床表现主要是局部疼痛和肿胀。影像学上,通常表现为髓内的溶解性病变,有时伴有周围硬化。目前,Rosai-Dorfman病的病因尚不明确,可能涉及潜在的宿主免疫失调、IgG4相关疾病、多种自身免疫性疾病和基因突变等。目前伴有症状的骨骼Rosai-Dorfman病的治疗方案主要取决于具体病灶位置,主要包括手术刮除或切除,其他治疗方案包括激素治疗和化疗等。由于骨骼Rosai-Dorfman病的临床和影像学表现通常提示恶性病变可能,部分患者可能接受比较激进的治疗。全身PET/CT可以用于Rosai-Dorfman病的分期、随访和评估。

关键词：骨病 Rosai-Dorfman病窦组织细胞增生诊断治疗

基于自动铺放技术的高精度变刚度复合材料层合板屈曲性能

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复合材料学报 2020年第11期37卷 2807-2815页

作者：卫宇璇张明刘佳刘硕崔志刚北京卫星制造厂有限公司北京100094

基于自动铺放技术制备的曲线变刚度复合材料层合板,通过定制面内刚度,可有效提高结构的抗屈曲性能。在铺放过程中,铺放轨迹的路径规划是实现变刚度设计的关键技术之一。鉴于此,本文分别以纤维角度线性变化曲线、等曲率曲线及二次Bezier... 详细信息

基于自动铺放技术制备的曲线变刚度复合材料层合板,通过定制面内刚度,可有效提高结构的抗屈曲性能。在铺放过程中,铺放轨迹的路径规划是实现变刚度设计的关键技术之一。鉴于此,本文分别以纤维角度线性变化曲线、等曲率曲线及二次Bezier曲线构成的纤维轨迹为研究对象,对其压缩屈曲性能进行参数化分析。并利用有限元模型研究了铺丝头上丝带宽度对层合板型面精度和抗屈曲力学性能的影响。结果表明:在压缩工况下,二次Bezier曲线路径的抗屈曲性能最佳,等曲率曲线路径受曲率约束的影响最小。铺丝头丝束宽度一定,丝带宽度与重叠区域面积和抗屈曲性能呈负相关。使用最大的丝带宽度可最大程度地减小重叠区域面积,提高结构的型面精度,同时保证结构屈曲性能提高37.3%。

关键词：变刚度屈曲特性自动铺放 Bezier曲线纤维丝束