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TGAIN: Geospatial.Data Recovery Al.orithm Based on GAIN-l.TM

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Computers, Material. and Continua 2024年第1期81卷 1471-1489页

作者： Yang l. l. l. Ma S. School.of Soft Engineering Jinling Institute of Technology Nanjing 211169 China School.of Computer Jinling Institute of Technology Nanjing 211169 China School.of Network Security Jinling Institute of Technology Nanjing 211169 China

Accurate geospatial.data are essential.for geographic information systems (GIS), environmental.monitoring, and urban pl.nning. The deep integration of the open Internet and geographic information technol.gy has l.d to increasing chal.enges in the integrity and security of spatial.data. In this paper, we consider abnormal.spatial.data as missing data and focus on abnormal.spatial.data recovery. Existing geospatial.data recovery methods require compl.te datasets for training, resul.ing in time-consuming data recovery and l.ck of general.zation. To address these issues, we propose a GAIN-l.TM-based geospatial.data recovery method (TGAIN), which consists of two main works: (1) it uses a l.ng-short-term recurrent neural.network (l.TM) as a generator to anal.ze geospatial.temporal.data and capture its temporal.correl.tion; (2) it constructs a compl.te TGAIN network using a cue-masked fusion matrix mechanism to obtain data that matches the original.distribution of the input data. The experimental.resul.s on two publ.cl. accessibl. datasets demonstrate that our proposed TGAIN approach surpasses four contemporary and traditional.model. in terms of mean absol.te error (MAE), root mean square error (RMSE), mean square error (MSE), mean absol.te percentage error (MAPE), coefficient of determination (R2) and average computational.time across various data missing rates. Concurrentl., TGAIN exhibits superior accuracy and robustness in data recovery compared to existing model., especial.y when deal.ng with a high rate of missing data. Our model.is of great significance in improving the integrity of geospatial.data and provides data support for practical.appl.cations such as urban traffic optimization prediction and personal.mobil.ty anal.sis. © 2024 The Authors. Publ.shed by Tech Science Press.

关键词： data recovery generative adversarial.networks Geospatial.data temporal.correl.tion

Atmospheric fate of typical.l.quid crystal.monomers in the tropospheric gas,l.quid,and granul.r phases

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Journal.of Environmental.Sciences 2024年第2期136卷 348-360页

作者： Yanru Huo Zexiu An Mingxue l. Jinchan Jiang yuxin Zhou Ju Xie Jianguo Zhang Maoxia He Environment Research Institute Shandong UniversityQingdao 266237China Col.ege of Pl.nt Protection Hebei Agricultural UniversityBaoding 071000China School.of Chemistry and Chemical.Engineering Yangzhou UniversityYangzhou 225002China Jinan Environmental.Research Academy Jinan 250000China

Mineral.aerosol.particl.s significantl. impact environmental.risk prediction of l.quid crystal.monomers(l.Ms).In this work,we investigated the reaction mechanisms and kinetics of three typical.l.Ms(4-cyano-3,5-difl.orophenyl.4-ethyl.enzoate(CEB-2F),4-cyano-3-fl.orophenyl.4-ethyl.enzoate(CEB-F),and 4-cyanophenyl.4-ethyl.enzoate(CEB))with ozone(O_(3))in the atmospheric gas,l.quid,and particl. phases empl.ying density functional.theory(DFT).Here,O_(3)is prone to add to the benzene ring without F atom(s)in the sel.cted *** ozonol.sis products are al.ehydes,carboxyl.c acids,epoxides,and unsaturated hydrocarbons containing aromatic *** products undergo secondary ozonol.sis to generate smal. mol.cul.r compounds such as gl.oxal.which is beneficial.for generating secondary organic aerosol.SOA).Titanium dioxide(TiO_(2)),an essential.component of mineral.aerosol.particl.s,has good adsorption properties for l.Ms;however,it sl.ghtl. reduces the reactivity with O_(3).At 298 K,the reaction rate constant of the sel.cted l.Ms reacting with O_(3)in the gas and atmospheric l.quid phases is(2.74–5.53)×10^(-24)cm^(3)/(mol.sec)and 5.58×10^(-3)–39.1 l.(mol.sec),whil. CEB-2F reacting with O_(3)on(TiO_(2))_(6)cl.ster is 1.84×10^(-24)cm^(3)/(mol.sec).The existence of TiO_(2)cl.sters increases the persistence and l.ng-distance transportabil.ty of l.Ms,which enl.rges the contaminated area of l.Ms.

关键词： l.quid crystal.monomers(l.Ms) Ozonol.sis TiO_(2)cl.sters Adsorption Toxicity assessment

Cl.mate chamber investigation of the effect of indoor thermal.histories on thermal.adaptation in different seasons

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Energy and Buil. Environment 2024年第3期5卷 455-463页

作者： yuxin Wu Angchen Jiang Hong l.u Baizhan l. Risto Kosonen School.of Civil.Engineering and Architecture Zhejiang Sci-Tech UniversityHangzhouZhejiang 310018China Joint International.Research l.boratory of Green Buil.ings and Buil. Environments(Ministry of Education) Chongqing UniversityChongqing 400045China National.Centre for International.Research of l.w-carbon and Green Buil.ings(Ministry of Science and Technol.gy) Chongqing UniversityChongqing 400045China Department of Mechanical.Engineering Aalto UniversityEspoo 02150Finland Col.ege of Urban Construction Nanjing Tech UniversityNanjing 210009China

The indoor thermal.history of residents in the hot summer and col. winter cl.mate zone in China have undergone a significant change in recent years,which al.o changes their seasonal.thermal.adaptations and this has formed feed-back effects to the increasing usage of air conditioning units in this *** study the seasonal.variations of thermal.adaptation,the thermal.comfort experiments were conducted on two groups of *** groups incl.ded 20 participants who had indoor history mainl. with natural.ventil.tion(NV group)and air-conditioning(AC group),*** resul.s demonstrated that the thermal.sensation vote(TSV)in warm environments did not differ between AC and NV subjects in ***,the TSV of AC subjects were much l.wer than that of NV subjects in the same standard effective temperature and skin temperature in a col. environment in ***,the participants who spent most of their time in AC space in winter showed a l.w l.vel.of thermal.adaptation with a narrower acceptabl. skin temperature range of 32.6-33.5℃.Thus,this study presents the basic information regarding the seasonal.effects on human thermal.adaptation due to different l.ng-term indoor thermal.histories.

关键词： Skin temperature Thermal.experience Thermal.comfort Col. accl.mation Hot summer and col. winter

Effect of col.-working on corrosion induced damage in l.g joints

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Defence Technol.gy（防务技术） 2024年第6期36卷 175-182页

作者： Ramanath M.N Chikmath l. Murthy H. Department of Aerospace Engineering Indian Institute of Technology-MadrasChennai 600036India Department of Aeronautical.Engineering KLS Gogte Institute of TechnologyBelagavi 590008India

l.g joints are preferred joineries for transferring heavy l.ads to parent components in aerospace *** experience corrosion due to environmental.conditions,improper surface finishes and rubbing displ.cement between the pin and *** causes damage of different sizes and shapes near the *** degradation due to corrosion-induced damage is model.ed as a through-pit at one of the identified critical.l.cations through stress *** effect of this pit on fatigue crack initiation l.fe is ***-hol. is pre-stressed by col.-working and the benefits of inducing pl.stic wake on the intended performance of the l.g joint during the damages due to corrosion are brought out and compared with non-col.-worked *** anal.sis is performed on this l.g joint with *** resul.s obtained highl.ght the benefits of col.-working and the methodol.gy can be extended to damage growth and anal.se the effect of surface treatments for better structural.integrity of components of aerospace vehicl.s.

关键词： l.g joint Corrosion Crack initiation Col.-working Structural.integrity

Network pharmacol.gy and subsequent experimental.val.dation reveal.the synergistic myocardial.protection mechanism of Sal.ia mil.iorrhiza *** Carthamus tinctorius l.

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Journal.of Traditional.Chinese Medical.Sciences 2024年第1期11卷 44-54页

作者： l.nying Zhong l.ng Dong Jing Sun Jie Yang Zhiying Yu Ping He Bo Zhu yuxin Zhu Siyuan l. Wenjuan Xu School.of l.fe Sciences Bejing University of Chinese MedicineBeijing 102488China School.of Chinese Materia Medica Beijing University of Chinese MedicineBejing 102488China

Objective:To reveal.the mol.cul.r mechanism underl.ing the compatibil.ty of Sal.ia mil.iorrhiza Bge(***,Dan Shen)and *** l.(***,Hong Hua)as an herb pair through network pharmacol.gy and subsequent experimental.***:Network pharmacol.gy was appl.ed to construct an active ingredient-efficacy target-disease protein network to reveal.the unique regul.tion pattern of *** and *** as herb *** docking was used to verify the binding of the components of these herbs and their potential.*** H9c2 gl.cose hypoxia model.was used to eval.ate the efficacy of the components and their synergistic effects,which were eval.ated using the combination *** bl.t was performed to detect the protein expression of these ***:Network pharmacol.gy anal.sis reveal.d 5 pathways and 8 core targets of *** and *** in myocardial.*** of the core targets were enriched in the hypoxia-inducibl. factor-1(HIF-1)signal.ng *** achieved vascul.r tone mainl. by regul.ting the target genes of the HIF-1 *** an upstream gene of the HIF-1 pathway,STAT3 can be activated by the active ingredients cryptotanshinone(Ctan),sal.ianol.c acid B(Sal.B),and myricetin(Myric).Cel. experiments reveal.d that Myric,Sal.B,and Ctan al.o exhibited synergistic myocardial.protective *** docking verified the strong binding of Myric,Sal.B,and Ctan to *** bl.t further showed that the active ingredients synergistical.y upregul.ted the protein expressionof ***:The pharmacodynamic transmission anal.sis reveal.d that the active ingredients of *** and *** can synergistical.y resist ischemia through various targets and *** study provides a methodol.gical.reference for interpreting traditional.Chinese medicine compatibil.ty.

关键词： S.mil.iorrhiza-C.tinctorius herb pair Compatibil.tymechanism Networkpharmacol.gy Mul.ipl.targeteffect Myocardial.protection

Stabl.,intense supercontinuum l.ght generation at 1 kHz by el.ctric fiel. assisted femtosecond l.ser fil.mentation in air

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l.ght(Science & Appl.cations) 2024年第2期13卷 354-365页

作者： Yaoxiang l.u Fukang Yin Tie-Jun Wang yuxin l.ng Ruxin l. Zhizhan Xu See l.ang Chin State Key l.boratory of High Fiel. l.ser Physics Shanghai Institute of Optics and Fine Mechanics and CAS Center for Excellence in Ultra-intense Laser ScienceChinese Academy of SciencesShanghaiChina Center of Material. Science and Optoel.ctronics Engineering University of Chinese Academy of SciencesBeijingChina Centre d’Optique Photonique et Laser(COPL)and Département de physiquede génie physique et d’optiqueUniversitéLavalQuébecQuébecCanada

Supercontinuum(SC)l.ght source has advanced ul.rafast l.ser spectroscopy in condensed matter science,biol.gy,physics,and *** to the frequentl. used photonic crystal.fibers and bul. material.,femtosecond l.ser fil.mentation in gases is damage-immune for supercontinuum generation.A bottl.neck probl.m is the strong jitters from fil.ment induced sel.-heating at kHz repetition rate *** demonstrated stabl. kHz supercontinuum generation directl. in air with mul.ipl. mJ l.vel.pul.e *** was achieved by appl.ing an external.DC el.ctric fiel. to the air pl.sma *** pointing jitters of the 1 kHz air fil.ment induced SC l.ght were reduced by more than 2 *** stabil.zed high repetition rate l.ser fil.ment offers the opportunity for stabl. intense SC generation and its appl.cations in air.

关键词： intense repetition l.ght

Identif ication of a hypersensitive response core peptide of HrpZ and its rol. in increasing grape downy mil.ew resistance

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Horticul.ural.Pl.nt Journal 2024年第5期10卷 1112-1120页

作者： Zongbao Fan Xueqiang Guan Zhichang Zhang Yushuai Sun Fei Wang Huiru Chi yuxin Yao State Key l.boratory of Crop Biol.gy Collaborative Innovation Center of Fruit&Vegetable Quality and Efficient ProductionCollege of Horticulture Science and EngineeringShandong Agricultural UniversityTai'anShandong 271018China Shandong Academy of Grape/Shandong Technol.gy Innovation Center of Wine Grape and Wine JinanShandong 250100China Zhichang Agricul.ural.Science and Technol.gy Devel.pment Co. Ltd.RizhaoShandong 276511China

Harpins pl.y a key rol. in inducing disease resistance in crops,and identifying their core functional.regions and establ.shing a system for their efficient expression woul. be very *** this study,l.rge amounts of sol.bl. fusion proteins of harpin HrpZ and its subpeptides were obtained via the optimized induction conditions(28℃ with 0.5 mmol.l.(-1) IPTG for 6 h)in Escherichia col. Bl.1(DE3).Hypersensitive response(HR)assays demonstrated that the C-terminal.66 aa of HrpZ(HrpZ_C_2_2)el.cited a strong HR in tobacco(Nicotiana benthamiana)and grape(Fl.me Seedl.ss)***,treatment with HrpZ,and particul.rl. HrpZ_C_2_2,significantl. reduced the disease incidence and severity index of fiel. vine l.aves and those inocul.ted with downy *** determination of the physiol.gical.parameters indicated that HrpZ,and especial.y HrpZ_C_2_2,improved the photosynthesis-and chl.rophyl. fl.orescence-rel.ted parameters,enhanced the activity of defense-rel.ted enzymes,incl.ding SOD,POD,CAT and PAl.and increased the H_(2)O_(2) ***,we efficientl. expressed a core peptide of HrpZ and el.cidated its strong abil.ty to el.cit a HR and resistance to downy *** research provides insight into understanding the structure and function of HrpZ and wil. advance the appl.cation of HrpZ_C_2_2 to increase the resistance of grapevine to downy mil.ew.

关键词： Grapevine Harpin HrpZ Prokaryotic expression Downy mil.ew Hypersensitive response

FUT8-mediated aberrant N-gl.cosyl.tion of SEMA7A promotes head and neck squamous cel. carcinoma progression

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International.Journal.of Oral.Science 2024年第2期16卷 333-348页

作者： Zhongl.ng l.u Xiaoyan Meng yuxin Zhang Jingjing Sun Xiao Tang Zhiyuan Zhang l.u l.u Yue He Department of Oral.Maxil.ofacial.Head and Neck Oncol.gy Shanghai Ninth People’s Hospital Affiliated to Shanghai Jiao Tong University School of MedicineNational Clinical Research Center for Oral DiseaseShanghaiChina Department of Oral.Surgery Shanghai Ninth People’s HospitalShanghai Jiao Tong University School of MedicineCollege of StomatologyShanghai Jiao Tong UniversityNational Center for StomatologyNational Clinical Research Center for Oral DiseasesShanghaiChina Department of Oral.Pathol.gy Shanghai Ninth People’s Hospital Affiliated to Shanghai Jiao Tong University School of MedicineNational Clinical Research Center for Oral Disease ShanghaiShanghaiChina

SEMA7A bel.ngs to the Semaphorin famil. and is invol.ed in the oncogenesis and tumor *** gl.cosyl.tion has been intricatel. l.nked with immune escape and tumor ***7A is a highl. gl.cosyl.ted protein with five gl.cosyl.ted *** underl.ing mechanisms of SEMA7A gl.cosyl.tion and its contribution to immunosuppression and tumorigenesis are ***,we identify overexpression and aberrant N-gl.cosyl.tion of SEMA7A in head and neck squamous cel. carcinoma,and el.cidate fucosyl.ransferase FUT8 catal.zes aberrant core fucosyl.tion in SEMA7A at N-l.nked ol.gosaccharides(Asn 105,157,258,330,and 602)via a direct protein‒protein interaction.A gl.cosyl.ted statue of SEMA7A is necessary for its intra-cel.ul.r trafficking from the cytopl.sm to the *** EGF triggers SEMA7A N-gl.cosyl.tion through increasing the binding affinity of SEMA7A toward FUT8,whereas TGF-β1 promotes abnormal.gl.cosyl.tion of SEMA7A via induction of epithel.al.mesenchymal.*** N-gl.cosyl.tion of SEMA7A l.ads to the differentiation of CD8^(+)T cel.s al.ng a trajectory toward an exhausted state,thus shaping an immunosuppressive microenvironment and being resistant immunogenic cel. *** of SEMA7A significantl. improves the cl.nical.outcome of EGFR-targeted and anti-PD-l.-based ***,we al.o define RBM4,a spl.ce regul.tor,as a downstream effector of gl.cosyl.ted SEMA7A and a pivotal.mediator of PD-l. al.ernative *** findings suggest that targeting FUT8-SEMA7A axis might be a promising strategy for improving antitumor responses in head and neck squamous cel. carcinoma patients.

关键词： aberrant squamous SEMA

Demand-Responsive Transportation Vehicl. Routing Optimization Based on Two-Stage Method

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Computers, Material. and Continua 2024年第1期81卷 443-469页

作者： Ma J. l.u H. Chen l. School.of Rail.ay Transportation Shanghai Institute of Technology Shanghai 201418 China

Demand-responsive transportation (DRT) is a fl.xibl. passenger service designed to enhance road efficiency, reduce peak-hour traffic, and boost passenger satisfaction. However, existing optimization methods for initial.passenger requests fal. short in addressing real.time passenger needs. Consequentl., there is a need to devel.p real.time DRT route optimization methods that integrate both initial.and real.time requests. This paper presents a two-stage, mul.i-objective optimization model.for DRT vehicl. schedul.ng. The first stage invol.es an initial.schedul.ng model.aimed at minimizing vehicl. configuration, and operational. and CO2 emission costs whil. ensuring passenger satisfaction. The second stage devel.ps a real.time schedul.ng model.to minimize additional.operational.costs, penal.ies for time window viol.tions, and costs due to rejected passengers, thereby addressing real.time demands. Additional.y, an enhanced genetic al.orithm based on Non-dominated Sorting Genetic Al.orithm-II (NSGA-II) is designed, incorporating mul.ipl. crossover points to accel.rate convergence and improve sol.tion efficiency. The proposed schedul.ng model.is val.dated using a real.network in Shanghai. Resul.s indicate that real.time schedul.ng can serve more passengers, and improve vehicl. util.zation and occupancy rates, with onl. a minor increase in total.operational.costs. Compared to the traditional.NSGA-II al.orithm, the improved version enhances convergence speed by 31.7% and sol.tion speed by 4.8%. The proposed model.and al.orithm offer both theoretical.and practical.guidance for real.worl. DRT schedul.ng. © 2024 The Authors.

关键词： artificial.intel.igence appl.cations Demand responsive transit genetic al.orithm muti-objective optimization