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Solve the False-Positive Problem of the Mimic System Based on the Best Mimic Component Set

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China Communications 2022年第5期19卷 253-266页

作者： yuwen shao Zheng Zhang Xiaomei Wang Chuanxing Pan Jiangxing Wu State Key Laboratory of Mathematical Engineering and Advanced Computing Zhengzhou 450001China China National Digital Switching System Engineering and Technological R&D Center Zhengzhou 450002China

At present,there is a problem of false positives caused by the too vast mimic scope in mimic transformation *** studies have focused on the“compensation”method to deal with this problem,which is expensive and cannot fundamentally solve *** paper provides new insights into coping with the ***,this study summarizes the false-positive problem in the mimic transformation,analyzes its possible harm and the root ***,three properties about the mimic scope are *** on the three properties and security quantification technology,the best mimic component set theory is put forward to solve the false-positive *** are two algorithms,the supplemental method and the subtraction *** best mimic component set obtained by these two algorithms can fundamentally solve the mimic system’s false-positive problem but reduce the cost of mimic *** make up for the lack of previous researches.

关键词： mimic scope the best mimic component set false-positive rate mimic transformation

Long‐life lithium batteries enabled by a pseudo‐oversaturated electrolyte

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Carbon Energy 2024年第4期6卷 115-127页

作者： Youchun Yu Simeng Wang Juyan Zhang Weiwei Qian Nana Zhang Guangjie shao Haiyan Bian yuwen Liu Lan Zhang Hebei Key Laboratory of Applied Chemistry College of Environmental and Chemical EngineeringYanshan UniversityQinhuangdaoChina Beijing Key Laboratory of Ionic Liquids Clean Process CAS Key Laboratory of Green Process and EngineeringInstitute of Process EngineeringChinese Academy of SciencesBeijingChina Haike Group Research Institute of Innovation&Technology DongyingChina Langfang Green Industrial Technology Center LangfangChina

The specific energy of Li metal batteries(LMBs)can be improved by using high‐voltage cathode materials;however,achieving long‐term stable cycling performance in the corresponding system is particularly challenging for the liquid ***,a novel pseudo‐oversaturated electrolyte(POSE)is prepared by introducing 1,1,2,2‐tetrafluoroethyl‐2,2,3,3‐tetrafluoropropyl ether(TTE)to adjust the coordination structure between diglyme(G2)and lithium bis(trifluoromethanesulfonyl)imide(LiTFSI).Surprisingly,although TTE shows little solubility to LiTFSI,the molar ratio between LiTFSI and G2 in the POSE can be increased to 1:1,which is much higher than that of the saturation state,1:*** and experimental results prove that TTE promotes closer contact of the G2 molecular with Li^(+)in the ***,it also participates in the formation of electrolyte/electrode *** electrolyte shows outstanding compatibility with both the Li metal anode and typical high‐voltage ***||Li symmetric cells show a long life of more than 2000 h at 1 mA cm^(−2),1 mAh cm^(−2).In the meantime,Li||LiNi_(0.8)Co_(0.1)Mn_(0.1)O_(2)(NCM811)cell with the POSE shows a high reversible capacity of 134.8 mAh g^(−1 )after 900 cycles at 4.5 V,1 C *** concept of POSE can provide new insight into the Li^(+)solvation structure and in the design of advanced electrolytes for LMBs.

关键词： high voltage lithium metal batteries pseudo‐oversaturated electrolyte solid electrolyte interphases(SEI) solvation structure

维普期刊数据库评论

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16例急性有机磷中毒致呼吸肌麻痹的护理

天津护理 1999年第4期7卷 142-144页

作者：邵玉文天津市汉沽医院急症科 300480

通过对16例急性有机磷中毒致呼吸肌麻痹患者救治成功的护理,我们制定了有效的护理措施:呼吸道护理;病情观察;心理护理。防止或减少了并发症的发生,对提高抢救成功率起到了重要作用。

关键词：有机磷中毒呼吸肌麻痹护理

Microbiota enterotoxigenic Bacteroides fragilis-secreted BFT-1 promotes breast cancer cell stemness and chemoresistance through its functional receptor NOD1

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Protein & Cell 2024年第6期15卷 419-440页

作者： Wei Ma Lu Zhang Weilong Chen Zhaoxia Chang Juchuanli Tu Yuanyuan Qin yuwen Yao Mengxue Dong Jiajun Ding Siqin Li Fengkai Li Qiaodan Deng Yifei Yang Tingting Feng Fanrong Zhang Xiying shao Xueyan He Lixing Zhang Guohong Hu Quentin Liu Yi-Zhou Jiang Shu Zhu Zhi Xiao Dan Su Tong Liu Suling Liu Fudan University Shanghai Cancer Center & Institutes of Biomedical Sciences State Key Laboratory of Genetic EngineeringCancer InstitutesDepartment of OncologyKey Laboratory of Breast Cancer in ShanghaiThe Shanghai Key Laboratory of Medical EpigeneticsShanghai Key Laboratory of Radiation OncologyThe International Co-laboratory of Medical Epigenetics and MetabolismMinistry of Science and TechnologyShanghai Medical CollegeFudan UniversityShanghai 200032China Intelligent Pathology Institute and Department of Pathology The First Affiliated Hospital of USTCDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefei 230071China Department of Thyroid Breast and Vascular SurgeryXijing HospitalFourth Military Medical UniversityXi’an 710032China Institute of Immunology CAS Key Laboratory of Innate Immunity and Chronic DiseaseSchool of Basic Medical SciencesDivision of Life Science and MedicineUniversity of Science and Technology of ChinaHefei 230027China Department of Pathology The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital)Institute of Basic Medicine and Cancer (IBMC)Chinese Academy of SciencesHangzhou 310022China Department of Breast Surgery The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital)Institute of Basic Medicine and Cancer (IBMC)Chinese Academy of SciencesHangzhou 310022China Department of Breast Medical Oncology The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital)Institute of Basic Medicine and Cancer (IBMC)Chinese Academy of SciencesHangzhou 310022China Shanghai Institute of Nutrition and Health University of Chinese Academy of SciencesChinese Academy of SciencesShanghai 200031China Sun Yat-sen University Cancer Center State Key Laboratory of Oncology in South ChinaGuangzhou 510060China Department of Breast Surgery Xiangya HospitalChangsha 410008China Department of Breast Surgery Tumor Hospital of Harbin Medic

Tumor-resident microbiota in breast cancer promotes cancer initiation and malignant ***,targeting microbiota to improve the effects of breast cancer therapy has not been investigated in ***,we evaluated the microbiota composition of breast tumors and found that enterotoxigenic Bacteroides fragilis(ETBF)was highly enriched in the tumors of patients who did not respond to taxane-based neoadjuvant ***,albeit at low biomass,secreted the toxic protein BFT-1 to promote breast cancer cell stemness and *** studies showed that BFT-1 directly bound to NOD1 and stabilized NOD1 ***1 was highly expressed on ALDH+breast cancer stem cells(BCSCs)and cooperated with GAK to phosphorylate NUMB and promote its lysosomal degradation,thereby activating the NOTCH1-HEY1 signaling pathway to increase ***1 inhibition and ETBF clearance increase the chemosensitivity of breast cancer by impairing BCSCs.

关键词： NOD1 breast chemotherapy

KMBox:基于Linux内核改造的进程异构冗余执行系统

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信息安全学报 2023年第1期8卷 14-25页

作者：马博林张铮邵昱文李秉政潘传幸蒋鹏邬江兴中国人民解放军战略支援部队信息工程大学郑州450001 网络通信与安全紫金山实验室南京211100

随机化技术防御进程控制流劫持攻击,是建立在攻击者无法了解当前内存地址空间布局的基础之上,但是,攻击者可以利用内存信息泄露绕过随机化防御获得gadget地址,向程序注入由gadget地址构造的payload,继续实施控制流劫持攻击,窃取敏感数... 详细信息

随机化技术防御进程控制流劫持攻击,是建立在攻击者无法了解当前内存地址空间布局的基础之上,但是,攻击者可以利用内存信息泄露绕过随机化防御获得gadget地址,向程序注入由gadget地址构造的payload,继续实施控制流劫持攻击,窃取敏感数据并夺取或破坏执行软件的系统。目前,异构冗余执行系统是解决该问题的方法之一,基本思想是同一程序运行多个多样化进程,同时处理等效的程序输入。随机化技术使冗余的进程对恶意输入做出不同的输出,同时正常功能不受影响。近年来,一些符合上述描述的系统已经被提出,分析进程异构冗余执行系统的表决设计可以发现,基于ptrace的实现方法会引入大量的上下文切换,影响系统的执行效率。率先直接修改内核设计出一种进程异构冗余执行系统,表决过程完全在内核中完成,冗余的进程独立地采用内存地址空间随机化技术,构建相互异构的内存地址空间布局,在与内存信息泄露相关的系统调用处进行表决,发现泄露信息不一致,阻断进程控制流劫持攻击。即使攻击者跳过内存信息泄露进行漏洞利用,异构内存空间布局也使得注入由gadget地址构造的payload无法同时在冗余的进程中有效,阻断进程控制流劫持攻击。实现了原型系统KMBox,实验证明该系统能够有效抵御进程控制流劫持攻击,性能相较于基于ptrace的进程异构冗余执行系统有所提高。

关键词：控制流劫持攻击异构冗余执行系统随机化

BRCA1/2胚系突变对三阴性乳腺癌患者放疗后第二原发肿瘤的影响

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中国癌症杂志 2024年第2期34卷 185-190页

作者：胡晓钰蔡毓文叶富贵邵志敏胡伟刚余科达复旦大学附属肿瘤医院放疗科复旦大学上海医学院肿瘤学系上海200032 复旦大学附属肿瘤医院乳腺外科复旦大学上海医学院肿瘤学系上海200032

背景与目的:乳腺癌易感基因1/2(BRCA1/2)的编码产物在维持机体基因组稳定性方面发挥着重要的作用。BRCA1/2致病突变是否会导致机体对放射线的脆弱度增加,从而诱发第二原发肿瘤尚不清楚。本文旨在探讨BRCA1/2基因胚系突变的三阴性乳腺癌... 详细信息

背景与目的:乳腺癌易感基因1/2(BRCA1/2)的编码产物在维持机体基因组稳定性方面发挥着重要的作用。BRCA1/2致病突变是否会导致机体对放射线的脆弱度增加,从而诱发第二原发肿瘤尚不清楚。本文旨在探讨BRCA1/2基因胚系突变的三阴性乳腺癌患者术后接受放射治疗是否是增加罹患第二原发肿瘤的危险因素。方法:基于复旦大学附属肿瘤医院2007年1月1日—2014年12月31日收集的回顾性三阴性乳腺癌队列(292例为BRCA1/2突变的女性三阴性乳腺癌患者),针对其开展分析,分别在非BRCA1/2胚系突变患者(n=261)与BRCA1/2胚系突变患者(n=31)中进行多元logistic回归分析,以评估影响第二原发肿瘤的风险因素,并对上述两人群中的分析结果进行交互作用分析,从而评估BRCA1/2胚系突变与放疗的交互作用。本研究除特殊说明外,均采用双侧检验且检验水准α=0.05。本研究所有样本的获得与使用均得到了复旦大学附属肿瘤医院伦理委员会的批准(050432-4-2108),且每个患者均提供了书面知情同意。结果:在BRCA1/2胚系突变患者中进行多元logistic回归分析提示术后接受放疗相对于未接受放疗显著增加了第二原发肿瘤的风险[比值比(odds ratio,OR)=2.479,95%CI:1.971~3.118,P<0.001)。而在非BRCA1/2胚系突变患者中,放疗对第二原发肿瘤的效应则不显著。BRCA1/2胚系突变与放疗对于第二原发肿瘤的发生无显著的交互作用(OR=9.71,95%CI:0.32~295.25,P=0.193)。结论:虽然统计学分析结果显示,与未接受放疗的患者相比,BRCA1/2胚系突变的患者术后放疗会增加罹患第二原发肿瘤的风险,但BRCA1/2胚系突变与放疗对第二原发肿瘤的发生并无相互交叉作用,因而BRCA1/2胚系突变患者术后接受放疗可能并不会增加罹患第二原发肿瘤的风险。

关键词：乳腺癌 BRCA1 BRCA2 放疗第二原发肿瘤

Ti基MXenes表面氮气还原机理的第一性原理研究

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安徽工业大学学报（自然科学版） 2024年第3期41卷 265-275页

作者：邵翠萍王文杰程育汶安徽工业大学材料科学与工程学院安徽马鞍山243002 安徽工业大学先进金属材料绿色制造与表面技术教育部重点实验室安徽马鞍山243002

基于第一性原理,计算二维过渡金属碳氮化物(MXenes)Ti_(2)CT_(2)和Ti_(3)C_(2)T_(2)(T=O^(*)或OH^(*))催化剂表面N_(2)吸附前后的态密度(DOS)、反应中间结构的吉布斯自由能(△G)、差分电荷(CDD)、功函数φ及活化能(E_(a)),探究OH^(*)终端MXene表面发生N_(2)还原反应(NRR)反应的机制。结果发现:N_(2)在Ti_(2)CO_(2)和Ti_(3)C_(2)O_(2)表面发生物理吸附(△q≈0e),在Ti_(2)C(OH)_(2)和Ti_(3)C_(2)(OH)_(2)表面发生化学吸附(△q>0.2e),Ti_(2)CO_(2)(η_(NRR)=2.13 V)和Ti_(3)C_(2)O_(2)(η_(NRR)=2.03 V)催化剂由于过高的加氢过电位(η_(NRR))而不利于发生NRR;Ti_(2)C(OH)_(2)和Ti_(3)C_(2)(OH)_(2)表面可在起始步骤N_(2)吸附时提供H原子,并通过Enzymatic机制发生NRR,相应的ηNRR分别降至0.29,0.38 V;此外,η_(NRR)与功函数φ存在ηNRR=0.44φ−0.71函数关系,线性相关系数(R^(2))为0.97,两者存在较大的线性相关性;在^(*)OH终端与^(*)O终端表面N 2p轨道和O 2p轨道能级杂化强度不同,导致OH^(*)MXene的NRR活性不同。由此认为,N_(2)在Ti_(2)C(OH)_(2)和Ti_(3)C_(2)(OH)_(2)表面的N_(2)通过“N_(2)+2^(*)H=^(*)N_(2)H_(2)”进行吸附,然后沿Enzymatic机制进行NRR。

关键词：二维过渡金属碳氮化物氮气还原加氢第一性原理

Inter-comparisons of VOC oxidation mechanisms based on box model:A focus on OH reactivity

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Journal of Environmental Sciences 2022年第4期34卷 286-296页

作者： Xiaoyun Yang Bin Yuan Zhe Peng yuwen Peng Caihong Wu Suxia Yang Jin Li Min shao Institute for Environmental and Climate Research Jinan UniversityGuangzhou 511443China Guangdong-Hongkong-Macao Joint Laboratory of Collaborative Innovation for Environmental Quality Guangzhou 511443China Department of Chemistry and Cooperative Institute for Research in Environmental Sciences University of ColoradoBoulderCO 80309USA

Volatile organic compounds(VOCs)oxidation processes play a very important role in atmospheric chemistry,and the chemical reactions are expressed in various manners in chemical *** gain an improved understanding of VOCs evolution during oxidation processes and evaluate the discrepancies of VOCs oxidation schemes among different mechanisms,we used the total VOC reactivity as a diagnostic and evaluated tool to explore the differences for six widely used chemical *** compared the total VOC reactivity evolution under high-NO_(x)xconditions for several sets of precursors,including n-pentane,toluene,ethene,isoprene and a mixture of 57 Photochemical Assessment Monitoring Stations(PAMS)species in a 0-D photochemical box ***-comparison of total VOC reactivity of individual precursor simulations showed discrepancies to different extent of the oxidation schemes among the studied mechanisms,which are mainly attributed to the different lumping approaches for organic *** PAMS simulation showed smaller discrepancy than individual precursor cases in terms of total VOC ***07 and RACM2 performances are found to better match the MCM for simulation of total VOC *** suggest that the performance in simulating secondary organic products,OH concentrations and NO_(x)concentrations are related to the OH reactivity discrepancies among various chemical *** in this study can be used in selection of chemical mechanisms to better model OH reactivity in different *** results in this study also provide directions to further improve the ability in modelling total VOC reactivity with the chemical mechanisms.

关键词： VOCs Box model Chemical mechanism Total VOC reactivity VOC oxidation

Coherence of Superposition States

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Communications in Theoretical Physics 2019年第9期71卷 1084-1088页

作者： Shan-Shan yuwen Lian-He shao Zheng-Jun Xi College of Computer Science Shaanxi Normal UniversityXi'an710062China School of Computer Science Xi'an Polytechnic UniversityXi'an710048China

We find tight upper bound on the coherence of a superposition of two states in terms of the coherence of the two states constituting the superposition with l1-norm of coherence. Our upper bound is tighter than the one presented by Liu, et al. [Quantum Inf. Process. 15(2016) 4209.] We also generalize the results to the case that the superposition is constituted with more than two states in high dimension, and we give the corresponding upper bounds.

关键词： quantum coherence superposition states l1-norm of coherence