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Decreased incidence followed by comeback of pediatric infections during the COVID‑19 pandemic in Japan

World Journal of Pediatrics 2022年第8期18卷 564-567页

作者： Cyrus Ghaznavi Haruka Sakamoto Takayuki Kawashima Sayaka Horiuchi Masahiro Ishikane Sarah Krull Abe Daisuke Yoneoka Akifumi Eguchi yuta Tanoue Masahiro Hashizume Shuhei Nomura Department of Health Policy and Management School of MedicineKeio University35 ShinanomachiShinjuku-kuTokyo 160-8582Japan Medical Education Program Washington University School of Medicine in St.LouisSaint LouisUSA Department of Global Health Policy Graduate School of MedicineThe University of TokyoTokyoJapan Tokyo Foundation for Policy Research TokyoJapan Department of Hygiene and Public Health Tokyo Women’s Medical UniversityTokyoJapan Department of Mathematical and Computing Science Tokyo Institute of TechnologyTokyoJapan Center for Birth Cohort Studies University of YamanashiYamanashiJapan Disease Control and Prevention Center National Center for Global Health and MedicineTokyoJapan Division of Prevention National Cancer Center Institute for Cancer ControlTokyoJapan Infectious Disease Surveillance Center National Institute of Infectious DiseasesTokyoJapan Department of Sustainable Health Science Center for Preventive Medical SciencesChiba UniversityChibaJapan Institute for Business and Finance Waseda UniversityTokyoJapan

During the coronavirus disease 2019(COVID-19)pandemic,the Japanese government implemented several infection control measures,such as states of emergency(SoE)and school closures,and encouraged universal masking and hand *** activity restrictions and improved hygiene were found to be associated with declines in the incidence of infuenza during the 2019–2020 winter season[1].Prior studies have found that the incidence of seven pediatric infections,such as pharyngoconjunctivitis and varicella,decreased during and after the school closures in Japan[2].As activity restrictions continue to be lifted,there is growing concern that pediatric infections may suddenly return given that the pool of susceptible children increased during the pandemic[3].In this study,we use national infectious disease sentinel data from January 2012 to October 2021 to assess changes in the reported number of pediatric infections in Japan during the COVID-19 *** hypothesize that the reporting of many infectious diseases decreased during the early stages of the pandemic but ultimately returned to normal when activity restrictions were lifted.

关键词： closure return suddenly

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High Speed Observation of Periodic Cavity Behavior in a Convergent-Divergent Nozzle for Cavitating Water Jet

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Journal of Flow Control, Measurement & Visualization 2013年第3期1卷 102-107页

作者： Keiichi Sato yuta Taguchi Shota Hayashi Department of Mechanical Engineering Kanazawa Institute of Technology Nonoichi Japan

Cloud cavitation shows an unsteady periodic tendency under a certain flow condition. In a cavitating water jet flow with cavitation clouds, the cavities or the clouds produce high impact at their collapse. In order to make clear a mechanism of the periodic cavity behavior, we experimentally examine the behavior in a transparent cylindrical convergent-divergent nozzle using a high-speed video camera. An effect of upstream pressure fluctuation due to a plunger pump is investigated from a viewpoint of unsteady behavior in a cavitating water jet. As a result, it is found that the cavitating flow has two kinds of oscillation patterns in the cavity length (cavitation cloud region). One is due to the upstream pressure fluctuation caused by the plunger pump. The other is much shorter periodic motion related to the characteristic oscillation of cavitation clouds accompanied with the shrinking (reentrant), growing and shedding motion of the clouds.

关键词： Cloud Cavitation Periodic Behavior Water Jet High-Speed Video Observation Image Analysis

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Vibration Response Characteristics against the Radial and Axial Shocks on Small Size Hard Disk Drive Spindle Supported by Oil Film Bearings

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Journal of Mechanics Engineering and Automation 2014年第7期4卷 547-554页

作者： Masayuki Ochiai yuta Sunami Hiromu Hashimoto Department of Mechanical Engineering Tokai University Kanagawa 259-1292 Japan

This paper describes the experimental study on shock response of FDB （fluid dynamic bearing） spindle for HDDs （hard disk drives）. The FDBs are widely used as rotating shaft support elements for HDD spindle motors. Recently, the opportunity for the HDD spindle motors exposed to external vibration has been increasing because the HDDs are used for various information related equipment such as mobile PCs （personal computers）, video cameras, car navigation systems and so on. Hence, the rotating shaft has a possibility to come in contact with the bearing by external shocks and it causes wear or seizure to the bearing surface. To avoid the problem, it is extremely important to know how the spindle moves against the large shock on HDDs experimentally. However, as far as the authors know, there are few experimental studies treating the shock response of HDD spindles. In this paper, firstly, we propose a new test rig and experimental method for shock response of FDB spindles. Then the shock tests against the radial and axial disturbance on FDB spindle for 2.5＂ HDD are conducted. Finally, the experimental results of shock response waveforms and maximum displacement of disk are shown.

关键词： Tribology fluid film bearing hard disk drive spindle motor shock test shock response

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Identification Method of Dynamic Coefficients of Fluid Film Bearings for HDD Spindle Motors

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Journal of Mechanics Engineering and Automation 2014年第2期4卷 123-129页

作者： Masayuki Ochiai yuta Sunami Hiromu Hashimoto Department of Mechanical Engineering Tokai University Hiratsuka 259-1292 Japan

Fluid film bearings are widely used as support elements of rotating shaft for HDD （hard disk drive） spindle motors. Recently, the opportunity for the HDD spindle motors exposed to external vibration has been increasing because the HDDs are used for various information related equipments such as mobile PCs, car navigation systems. Hence, the rotating shaft has a possibility to come in contact with the bearing and it causes wear or seizure to the bearing surface. In order to avoid the problems, it is extremely important to enhance the dynamic characteristics of the fluid film bearings for spindles. However, verification from both theory and experiment of dynamic characteristics such as spring coefficients and damping coefficients is rare and few. In this paper, the bearing vibration characteristics when the HDD spindle is oscillated are investigated theoretically and experimentally. And then the identification method ofoil film coefficients of fluid film bearing spindles is described.

关键词： Tribology fluid film bearing hard disk drive spindle motor dynamic coefficient vibration identification.

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Intelligent Wind Power Unit with Tandem Wind Rotors and Armatures （Optimization of Front Blade Profile）

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Journal of Energy and Power Engineering 2012年第11期6卷 1791-1799页

作者： yuta Usui Koichi Kubo Toshiaki Kanemoto Graduate School of Engineering Kyushu Institute of Technology Kitakyushu 804-8550 Japan Kyushu Institute of Technology Kitakyushu 804-8550 Japan Faculty of Engineering Kyushu Institute of Technology Kitakyushu 804-8550 Japan

The authors have invented the superior wind power unit, which is composed of the tandem wind rotors and the double rotational armature type generator without the traditional stator. The large-sized front wind rotor and the small-sized rear wind rotor drive, as for the upwind type, the inner and the outer rotational armatures, respectively, in keeping the rotational torque counter-balanced between both wind rotors/armatures. The unique rotational behaviors of the tandem wind rotors and the fundamental performances of the unit have been discussed at the previous paper. Continuously, this paper investigates experimentally and numerically the flow condition around the wind rotors to know the flow interactions between the front and the rear wind rotors, and optimizes the blade profile in the front wind rotor. The front blade should work fruitfully at the larger radius and had better not work at the smaller radius for giving plenty of wind energy to the rear wind rotor, taking account of the flow interaction between both wind rotors.

关键词： Wind turbine wind energy blade tandem wind rotors generator armature numerical simulation.

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Allergic reaction to anisakis-contaminated fish after the first administration of BNT162b2 mRNA vaccine:a case report

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Gastroenterology Report 2022年第1期10卷 650-652页

作者： Fumiue Harada Kana Yamamoto Tomoki Matsuda Chika Yamamoto yuta Tani Mutsuko Ohnishi Morihito Takita Tetsuya Tanimoto Masahiro Kami Ryusaburo Shineha Department of Internal Medicine Soma Central HospitalSomaFukushimaJapan Department of Disaster and Comprehensive Medicine Fukushima Medical UniversityFukushimaFukushimaJapan Department of Radiation Health Management Fukushima Medical UniversityFukushimaFukushimaJapan Research Division Medical Governance Research InstituteMinatoTokyoJapan

Introduction SARS-CoV-2 vaccination is an effective means to prevent severe illness and death due to SARS-CoV-2 infection[1].Vaccine safety has been carefully monitored to be sure that the benefit outweighs the risk of adverse events(AEs).Common AEs of the BNT162b2 mRNA vaccine,for example,include fatigue(45%),headache(40%),and chills(28%)after the first administration in accordance with the adult phase Ⅲ clinical trial[1].

关键词： headache death administration

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Pre-hepatectomy type Ⅳ collagen 7S predicts post-hepatectomy liver failure and recovery

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World Journal of Gastroenterology 2020年第7期26卷 725-739页

作者： Masatsugu Ishii Osamu Itano Masahiro Shinoda Minoru Kitago yuta Abe Taizo Hibi Hiroshi Yagi Ayano Takeuchi Hanako Tsujikawa Tokiya Abe Yuko Kitagawa Department of Surgery Keio University School of MedicineTokyo 160-8582Japan Department of Hepato-Biliary-Pancreatic and Gastrointestinal Surgery International University of Health and Welfare School of MedicineChiba 286-8686Japan Department of Pediatric Surgery and Transplantation Kumamoto UniversityKumamoto 860-8556Japan Department of Public Health Keio University School of MedicineTokyo 160-8582Japan Department of Pathology Keio University School of MedicineTokyo 160-8582Japan

BACKGROUND Liver resection is an effective treatment for benign and malignant liver ***,a method for preoperative evaluation of hepatic reserve has not yet been *** reported assessments of preoperative hepatic reserve focused only on liver failure in the early postoperative period and did not consider the long-term recovery of hepatic *** determining eligibility for hepatectomy,the underlying pathophysiology needs to be considered to determine if the functional hepatic reserve can withstand both surgery and any postoperative *** To identify pre-hepatectomy factors associated with both early postoperative liver failure and long-term postoperative liver function *** This study was a retrospective cohort *** retrospectively investigated 215 patients who underwent hepatectomy at our hospital between May 2013 and December *** post-hepatectomy liver failure(PHLF)was defined using the International Study Group of Liver Surgery’s definition of ***-term postoperative recovery of liver function was defined as the time taken for serum total bilirubin and albumin levels to return to levels of2.8 g/dL,respectively,and the time taken for Child-Pugh score to return to Child-Pugh class *** Preoperative type IV collagen 7S was identified as a significant independent factor associated with both PHLF and postoperative long-term recovery of liver *** analysis revealed that the time taken for the recovery of Child-Pugh scores and serum total bilirubin and albumin levels was significantly shorter in patients with type IV collagen 7S≤6 ng/mL than in those with type IV collagen 7S>6 ng/*** additional analyses,similar results were observed in patients without chronic viral hepatitis associated with *** Preoperative type IV collagen 7S is a preoperative predictor of PHLF and longterm postoperative liver function *** can also be used in patients without chron

关键词： Hepatectomy Liver failure Type Ⅳ collagen 7S Liver fibrosis Postoperative complications Long-term postoperative liver function recovery

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Rescue case of low birth weight infant with acute hepatic failure

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World Journal of Gastroenterology 2017年第40期23卷 7337-7342页

作者： Noriki Okada Yukihiro Sanada Taizen Urahashi Yoshiyuki Ihara Naoya Yamada yuta Hirata Takumi Katano Kentaro Ushijima Shinya Otomo Shujiro Fujita Koichi Mizuta Department of Transplant Surgery Jichi Medical University Department of Clinical Pharmacology Jichi Medical University Department of Pharmacy Jichi Medical University Department of Pediatrics Yokohama City University School of Medicine

We report a case involving a rescued low birth weight infant(LBWI) with acute liver failure. Case: The patient was 1594 g and 32^(3/7) gestational wk at birth. At the age of 11 d, she developed acute liver failure due to gestational alloimmune liver disease. Exchange transfusion and high-dose gamma globulin therapy were initiated, and body weight increased with enteral nutrition. Exchange transfusion was performed a total of 33 times prior to living donor liver transplantation(LDLT). Her liver dysfunction could not be treated by medications alone. At 55 d old and a body weight of 2946 g, she underwent LDLT using an S2 monosegment graft from her mother. Three years have passed with no reports of intellectual disability or liver dysfunction. LBWIs with acute liver failure may be rescued by LDLT after body weight has increased to over 2500 g.

关键词： Liver transplantation Acute liver failure Low birth weight infant Transplantable body weight Monosegment graft

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Comparison of clinical trial registry systems and registered trials between Japan and China

Comparison of clinical trial registry systems and registered...

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第三届中日双边药理学和临床药理学学术会议

作者： TSUTANI Kiichiro OISHI yuta Dept.of Drug Policy and Management Graduate School of Pharmaceutical SciencesUniversity of TokyoJapan Dept.of Drug Policy and Management Graduate School of Pharmaceutical SciencesUniversity of TokyoJapan

＜正＞AIM Awareness of clinical trial registry （CTR） has increased globally since the International Committee of Medical Journal Editors （ICMJE） adopted in 2004 a trials-registration *** also established the International Clinical Trial Registry Platform （ICTRP, http://***/ictrp/）.There are currently 4 CTRs in Asia,3 in Japan and 1 in *** study ex- amines the 4 systems in terms of organization,review process,characteristics of the trials registered,etc. METHODS Information was collected through Internet and *** Japan established UMIN- CTR（http://***/ctr）,the first CTR in an academic setting,in June *** is one of the five CTRs in the world recognized by ICMJE.626 trials （mostly pub- licly-funded） were registered in UMIN-CTR as of 30 April *** July 2005,JAPIC-CTI （http://***- ***） was established by industry-funded *** registry has 532 registered drug trials （mostly industry- funded）.In December 2005,JMA-CCT （https://dbcen- ***,***/ctrialr/） was established by Ja- pan Medical ***-CCT is unique because all 9 trials registered are publicly-funded trials to be used to support future NDAs.A web portal is planned to be set up to link all CTRs in *** April 2006,China estab- lished ChiCTR （http://***/）.Twenty-two trials were submitted for posting in this registry but only 12 trials were officially *** the 12 registered trials, all but one are *** trials are in the field of traditional Chinese medicine,including a comparative study of traditional Chinese and Western *** nine journals in China have adopted a trials-registration policy,but the level of awareness of this policy is still low.

关键词： clinical trial registry Japan China Comparison ICMJE ICTRP

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Two cases of pancreatic ductal adenocarcinoma with intrapancreatic metastasis

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World Journal of Gastroenterology 2016年第41期22卷 9222-9228页

作者： Yusuke Fujita Minoru Kitago Yohei Masugi Osamu Itano Masahiro Shinoda yuta Abe Taizo Hibi Hiroshi Yagi Yoko Fujii-Nishimura Michiie Sakamoto Yuko Kitagawa Department of Surgery Keio University School of Medicine Department of Pathology Keio University School of Medicine

There are no standardized diagnostic criteria for intrapancreatic metastasis of pancreatic ductal adenocarcinoma(PDAC). Here, we report two cases of patients with PDAC who were pathologically diagnosed as harboring intrapancreatic metastasis. In both cases, the main lesions were located in the pancreatic body, and no other lesion was detected preoperatively. The patients were diagnosed with pancreatic body cancers and distal pancreatectomy was performed. Pathological findings revealed microscopic cancer nests, which had connections to neither the main lesion nor the premalignant lesion in the pancreatic tail parenchyma. In both cases, the histological type of the daughter lesion was quite similar to that of the main lesion. Hence, we diagnosed the daughter lesions as metastatic foci in the pancreas. Although intrapancreatic metastasis of PDAC has been regarded as a poor prognostic factor, few reports of intrapancreatic metastasis are available. This article reports two such cases and provides a review of the literature.

关键词： Carcinoma Pancreatic ductal Neoplasm micrometastasis Recurrence Carcinogenesis

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