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Photonic Sensors 2019年第1期9卷 11-18页

作者： Atsushi MOTOGAito yusuke ito Graduate School of Engineering Mie UniversityMie 514-8507Japan Iga Satellite Mie UniversityMie 518-0131Japan

The excitation mechanism of surface plasmon polaritons(SPPs)in a surface plasmon sensor with a one-dimensional(1D)Au diffraction grating on a glass substrate is studied *** sensitivity of the sensor for application to a refractometer is also *** SPPs are excited at the following two types of interface:one between the Au grating and the glass substrate and the other between the Au grating and the *** simulation data for the transmittance spectra and the transmittance mapping are consistent With the experimental data even when the refractive index of the solution medium is ***,the excitation mechanism of the SPPs in a surface plasmon sensor is capable of detecting the medium(n=1.700),in which the sensor is used and clarified.

关键词： Surface plasmon diffraction grating high refractive index chemical sensor

Clinical features in proven and probable invasive fungal disease in children and adolescents at a pediatric referral center: a 5-year experience

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World Journal of Pediatrics 2019年第3期15卷 270-275页

作者： Kenji Kishimoto Masashi Kasai Noriko Kawamura yusuke ito Makiko Yoshida Daiichiro Hasegawa Keiichiro Kawasaki Yoshiyuki Kosaka Department of Hematology and Oncology Children’s Cancer CenterKobe Children’s HospitalMinatojima—Minamimachi 1—6-7Chuo—kuKobe 650—0047 Japan Department of Infectious Disease Kobe Children’s Hospital KobeJapan Department of Clinical Laboratory Kobe Children’s HospitalKobeJapan Department of Diagnostic Pathology Kobe Children’s HospitalKobeJapan Department of Pediatrics Kita—Harima Medical Center KobeJapan

Background There is limited information concerning the overall epidemiology of invasive fungal disease (IFD) in *** aim of this study was to clarify the clinical features of IFD in a tertiary pediatric care *** Patients diagnosed with proven or probable IFD at our hospital between 2011 and 2015 were retrospectively *** and probable IFD were defined according to the European Organization for Research and Treatment of Cancer/Cancer/Invasive Fungal Infections Cooperative Group and the National Institute of Allergy and Infectious Diseases Mycoses Study Group *** with possible IFD were *** The incidence of proven or probable IFD was 26 of 20,079 hospitalized patients (0.13%).The predominant underlying disease was malignancy (54%) and congenital anomaly (27%).The most common diagnosis was candidemia among the patients with proven IFD (8 of 13,62%).All the isolated pathogens in the candidemia patients were non-albicans Candida *** most common site of infection was the lungs in patients with probable IFD (11 of 13 patients,85%).In probable IFD episodes,positive β-D-glucan and galactomannan were found in 12 of 13 (92%) and 5 of 13 (38%) patients,*** but one patient (96%) received empirical antifungal *** patients underwent surgical resection of residual *** overall mortality was 23% and the attributable mortality of IFD was 12%.Conclusion Our results suggest the emergence of non-albicans Candida species as important pathogens in childhood IFD.

关键词： Children Invasive fungal disease Incidence Mortality

Major hepatectomy using the glissonean approach in cases of right umbilical portion

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World Journal of Hepatology 2016年第34期8卷 1535-1540页

作者： yusuke Ome Kazuyuki Kawamoto Tae Bum Park Tadashi ito Department of Surgery Kurashiki Central Hospital

Right umbilical portion(RUP) is a rare congenital anomaly associated with anomalous ramifications of the hepatic vessels and biliary system. As such, major hepatectomy requires a careful approach. We describe the usefulness of the Glissonean approach in two patients with vessel anomalies, such as RUP. The first patient underwent a right anterior sectionectomy for intrahepatic cholangiocarcinoma. We encircled several Glissonean pedicles that entered the right anterior section along the right side of the RUP. We temporarily clamped each pedicle, confirmed the demarcation area, and finally cut them. The operation was performed safely and was successful. The second patient underwent a left trisectionectomy for perihilar cholangiocarcinoma. We secured the right posterior Glissonean pedicle. The vessels in the pedicle were preserved, and the other vessels and contents were resected. Identifying the vessels for preservation facilitated the safe lymphadenectomy and dissection of the vessels to be resected. We successfully performed the operation.

关键词： Right anterior sectionectomy Right umbilical portion Glissonean approach Left trisectionectomy Glissonean pedicle Cholangiocarcinoma Hepatocellular carcinoma

Retroperitoneal fibrosis associated with immunoglobulin G4-related disease

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World Journal of Gastroenterology 2013年第1期19卷 35-41页

作者： Nao Fujimori Tetsuhide ito Hisato Igarashi Takamasa Oono Taichi Nakamura yusuke Niina Masayuki Hijioka Lingaku Lee Masahiko Uchida Ryoichi Takayanagi Department of Medicine and Bioregulatory Science Graduate School of Medical SciencesKyushu UniversityFukuoka 812-8582Japan

Retroperitoneal fibrosis is a rare disease characterized by the development of inflammation and fibrosis in the soft tissues of the retroperitoneum and other abdominal *** fibrosis can be of 2 types:idiopathic and *** recently advocated concept and diagnostic criteria of immunoglobulin G4(IgG4)-related disease,derived from research on autoimmune pancreatitis(AIP),has led to widespread recognition of retroperitoneal fibrosis as a condition caused by IgG4-related *** now know that previously diagnosed idiopathic retroperitoneal fibrosis includes IgG4-related disease;however,the actual prevalence is ***,some reports on AIP suggest that retroperitoneal fibrosis is concurrently found in about 10% of IgG4-related *** retroperitoneal fibrosis has no specific symptoms,diagnosis is primarily based on diagnostic imaging(computed tomography and magnetic resonance imaging),which is also useful in evaluating the effect of *** retroperitoneal fibrosis can occur at different times with other lesions of IgG4-related disease including ***,the IgG4 assay is recommended to diagnose idiopathic retroperitoneal *** serum IgG4 levels should be treated and monitored as a symptom of IgG4-related *** first line of treatment for retroperitoneal fibrosis is steroid therapy regardless of its *** patients with concurrent AIP,i.e.,IgG4-related retroperitoneal fibrosis,the starting dose of steroid is usually 30-40 mg/*** response to steroid therapy is generally *** most cases,the pancreatic lesion and retroperitoneal fibrosis improve after the initial ***,the epidemiology,treatment for recurring retroperitoneal fibrosis,and long-term prognosis are still largely *** analysis of such cases and research are necessary.

关键词： Autoimmune pancreatitis Extrapancreatic lesion Immunoglobulin G4 Immunoglobulin G4related disease Retroperitoneal fibrosis

Detecting Unstable Periodic Orbits in Hyperchaotic Systems Using Subspace Fixed-Point Iteration

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Journal of Measurement Science and Instrumentation 2010年第S1期1卷 53-56页

作者： Hidetaka ito yusuke MOCHIDA Akira KUMAMOTO Department of Electrical and Electronic Engineering Kansai University

We present a numerical method for efficiently detecting unstable periodic orbits(UPO’s)embedded in chaotic attractors of high-dimensional *** method,which we refer to as subspace fixed-point iteration, locates fixed points of Poincare maps using a form of fixed-point iteration that splits the phase space into appropriate *** this paper,among a number of possible implementations,we primarily focus on a subspace method based on the Schmelcher-Diakonos(SD)method that selectively locates UPO’s by varying a stabilizing matrix,and present some applications of the resulting subspace SD method to hyperchaotic attractors where the UPO’s have more than one unstable direction.

关键词： nonlinear dynamics chaos unstable periodic orbits numerical analysis subspaces

Land-Ocean Linkage: Pelagic Cherts in Mesozoic Neritic-Terrestrial Sequences in East Asia

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Open Journal of Geology 2019年第10期9卷 551-553页

作者： Atsushi Matsuoka Tsuyoshi ito yusuke Sakai Department of Geology Niigata University Niigata Japan Research Institute of Geology and Geoinformation Geological Survey of Japan AIST Tsukuba Japan Graduate School of Science and Technology Niigata University Niigata Japan Ono City Board of Education Ono Japan

Chert clast-bearing epi-continental neritic-terrestrial Jurassic and Cretaceous sequences are sporadically distributed in southwestern Japan. Typical and geological entities are the Torinosu Group and Tetori Group. Radiolarian dating of chert clasts enables us to discuss denudation stages of mid Mesozoic accretionary complexes. Chert clast-dominated conglomerate can be used for identifying marine beds within terrestrial sequences.

关键词： Pelagic Radiolarian Chert Conglomerate Accretionary Complex Neritic-Terrigenous Sediments

Comparison of fecal calprotectin levels and endoscopic scores for predicting relapse in patients with ulcerative colitis in remission

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World Journal of Gastroenterology 2023年第47期29卷 6111-6121页

作者： Natsuki Ishida Tatsuhiro ito Kenichi Takahashi yusuke Asai Takahiro Miyazu Tomohiro Higuchi Satoshi Tamura Shinya Tani Mihoko Yamade Moriya Iwaizumi Yasushi Hamaya Satoshi Osawa Ken Sugimoto Department of Endoscopic and Photodynamic Medicine Hamamatsu University of School of MedicineHamamatsu 431-3192Japan First Department of Medicine Hamamatsu University of School of MedicineHamamatsu 431-3192Japan Department of Laboratory Medicine Hamamatsu University of School of MedicineHamamatsu 431-3192Japan

BACKGROUND Although the usefulness of endoscopic scores,such as the Mayo Endoscopic Subscore(MES),Ulcerative Colitis Endoscopic Index of Severity(UCEIS),and Ulcerative Colitis Colonoscopic Index of Severity(UCCIS),and biomarkers such as fecal calprotectin(FC)for predicting relapse in ulcerative colitis(UC)has been reported,few studies have included endoscopic scores for evaluating the entire *** To compare the usefulness of FC value and MES,UCEIS,and UCCIS for predicting relapse in patients with UC in clinical *** In total,75 patients with UC in clinical and endoscopic remission who visited our institution between February 2019 and March 2022 were *** diagnosis of UC was confirmed based on the clinical presentation,endoscopic findings,and histology,according to the current established criteria for *** samples were collected the day before or after the colonoscopy for measurement of *** evaluations were performed using MES,UCEIS,and *** primary outcome measure of this study was the assessment of the association between relapse within 12 mo and MES,UCEIS,UCCIS,and *** secondary outcome was the comparison between endoscopic scores and biomarkers in en-rolled patients with UC with mucosal *** and UCCIS showed a significant correlation with UCEIS (r = 0.537, P < 0.001 and r = 0.957, P < 0.001, respectively).Receiver-operating characteristic analysis for predicting MES 0 showed that the area under the curve ofUCCIS was significantly higher than that of FC (P < 0.01). During the 1-year observation period, 18 (24%) patientsexperienced a relapse, and both the FC and UCCIS of the relapse group were significantly higher than that of theremission group. The cut-off values for predicting relapse were set at FC = 323 mg/kg and UCCIS = 10.2. The areaunder the curve of the receiver-operating characteristic analysis for predicting relapse did not show a significantdifference between FC and UCCIS. The accuracy of the

关键词： Ulcerative colitis Mayo Endoscopic Subscore Ulcerative Colitis Endoscopic Index of Severity Ulcerative Colitis Colonoscopic Index of Severity Fecal calprotectin Relapse

Laparoscopic appendectomy for acute appendicitis: How to discourage surgeons using inadequate therapy

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World Journal of Gastroenterology 2017年第32期23卷 5849-5859页

作者： tomohide hori takafumi machimoto yoshio kadokawa toshiyuki hata tatsuo ito shigeru kato daiki yasukawa yuki aisu yusuke kimura maho sasaki yuichi takamatsu taku kitano shigeo hisamori tsunehiro yoshimura department of gastrointestinal surgery tenriyorodusoudanjyo hospital

Acute appendicitis(AA) develops in a progressive and irreversible manner, even if the clinical course of AA can be temporarily modified by intentional medications. Reliable and real-time diagnosis of AA can be made based on findings of the white blood cell count and enhanced computed tomography. Emergent laparoscopic appendectomy(LA) is considered as the first therapeutic choice for AA. Interval/delayed appendectomy at 6-12 wk after disease onset is considered as unsafe with a high recurrent rate during the waiting time. However, this technique may have some advantages for avoiding unnecessary extended resection in patients with an appendiceal mass. Nonoperative management of AA may be tolerated only in children. Postoperative complications increase according to the patient's factors, and temporal avoidance of emergent general anesthesia may be beneficial for high-risk patients. The surgeon's skill and cooperation of the hospital are important for successful LA. Delaying appendectomy for less than 24 h from diagnosis is safe. Additionally, a semi-elective manner(i.e., LA within 24 h after onset of symptoms) may be paradoxically acceptable, according to the factors of the patient, physician, and institution. Prompt LA is mandatory for AA. Fortunately, the Japanese government uses a universal health insurance system, which covers LA.

关键词： Laparoscopic appendectomy Acute appendicitis Interval appendectomy Surgery Delayed appendectomy

Morphology Observation of Novel 3, 4-Bis-Alkyloxycarbonyl-Hexanedioic Acid Monolayer on Water Surface by Dropping Method

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Journal of Biophysical Chemistry 2016年第2期7卷 43-48页

作者： yusuke Kobayashi Rina Hirai Daiki ito Yasushi Yamamoto Keijiro Taga Zameer Shervani Department of Life Science and Material Engineering Nagoya Institute of Technology Nagoya Japan Department of Life Science and Material Engineering Nagoya Institute of Technology Nagoya Japan 2Tohoku Foods Corporation Limited Sendai Japan Tohoku Foods Corporation Limited Sendai Japan

We have investigated the morphology of novel 3, 4-bis-alkyloxycarbonyl-hexanedioic acid monolayer (alkyl chain number n = 12, 14, and 16) formed on the water surface by dropping method using Surface Tension measurement (STm) and Brewster Angle Microscopy (BAM). Surfactant of 3, 4-bis-alkyloxycarbonyl-hexanedioic acid has a gemini type structure. π-A isotherm curves (STm) of two gemini surfactants of n = 12 and 14 showed gradual increase in surface pressure, while that of n = 16 showed gradual increase, a stagnant range and finally steep increase. BAM observation showed each image corresponding to the result of STm measurement. From STm and BAM results of surfactants, it is found that surfactant of n = 12 and 14 form Liquid-Expand (LE) type monolayer, while that of n = 16 formed Liquid-Condensed (LC) type monolayer including LE-LC phase transition.

关键词： 3 4-Bis-Alkyloxycarbonyl-Hexanedioic Acid Gemini Surfactants Gemsurfs Monolayer Morphology

COVID-19-associated disseminated mucormycosis:An autopsy case report

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World Journal of Clinical Cases 2022年第28期10卷 10358-10365页

作者： Daisuke Kyuno Terufumi Kubo Mitsuhiro Tsujiwaki Shintaro Sugita Michiko Hosaka Hazuki ito Keisuke Harada Akira Takasawa Yusaku Kubota Kumi Takasawa yusuke Ono Kazufumi Magara Eichi Narimatsu Tadashi Hasegawa Makoto Osanai Department of Pathology Sapporo Medical UniversitySapporo 0608556HokkaidoJapan Department of Surgical Pathology Sapporo Medical UniversitySapporo 0608556Japan Department of Emergency Medicine Sapporo Medical UniversitySapporo 0608556Japan

BACKGROUND Reports of mucormycosis,an infectious disease that commonly affects immunocompromised individuals,have increased during the ongoing coronavirus disease 2019(COVID-19) *** mucormycosis associated with COVID-19 is rare but fatal and is characterized by an aggressive clinical course and delayed *** report documents a case of disseminated mucormycosis after COVID-19 *** is a rare pathological autopsy report on COVID-19-associated *** SUMMARY A 58-year-old man was transferred to our hospital with severe COVID-19 *** treatment for acute respiratory distress syndrome,he developed intra-abdominal bleeding that required a right hemicolectomy and ileostomy for *** ileostoma and surgical wound developed necrosis followed by sepsis and multi-organ failure,which led to *** autopsy revealed multiple thrombi associated with Rhizopus oryzae infection,which led to the necrosis of multiple infected *** Early suspicion and diagnosis followed by treatment are keys to better outcomes of mucormycosis in patients with severe COVID-19.

关键词： COVID-19 Mucormycosis Mucorales infection Rhizopus oryzae SARS-Co V-2 Case report