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Chinese Journal of Aeronautics 2018年第9期31卷 1829-1841页

作者： Jianhua PAN Qian WANG yusi zhang Yuxin REN School of Aerospace Engineering Tsinghua University

In the present paper, high-order finite volume schemes on unstructured grids developed in our previous papers are extended to solve three-dimensional inviscid and viscous flows. The highorder variational reconstruction technique in terms of compact stencil is improved to reduce local condition numbers. To further improve the efficiency of computation, the adaptive mesh refinement technique is implemented in the framework of high-order finite volume methods. Mesh refinement and coarsening criteria are chosen to be the indicators for certain flow structures. One important challenge of the adaptive mesh refinement technique on unstructured grids is the dynamic load balancing in parallel computation. To solve this problem, the open-source library p4 est based on the forest of octrees is adopted. Several two-and three-dimensional test cases are computed to verify the accuracy and robustness of the proposed numerical schemes.

关键词： Adaptive mesh refinement Compact stencil High-order finite volume scheme Unstructured grids Variational reconstruction

Time-Domain Dual Component Computation Diversity Based on Generalized Hybrid Carrier

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China Communications 2021年第10期18卷 148-157页

作者： Yuqing Feng Xuejun Sha Yong Li Xiaojie Fang yusi zhang School of Electronics and Information Engineering Harbin Institute of TechnologyHarbin 150001China Science and Technology on Communication Networks Laboratory Shijiazhuang 050080China The 54th Research Institute of China Electronics Technology Group Corporation Shijiazhuang 050081China Engineering Research Center for Dedicated Communication System Ministry of EducationHarbin 150080China

In this paper,the concept of computation diversity is proposed by employing generalized hybrid carrier(GHC)*** signal is backed up by transform-domain computation to enhance the anti-fading *** analysis is presented to demonstrate the superiority of the proposed *** simulations in doubly-selective fading channels are provided to verify the *** bit error rate(BER)performance is guaranteed with a small computational complexity *** proposed method not only extends the new diversity dimension,but also improves the diversity gain of the system without occupying additional wireless ***,the proposed method shows good adaptability with single carrier modulation and improves diversity *** the simulation results shown,time-domain dual component computation diversity(TDC-CD)has 1d B BER gain and 0.1diversity gain at high signal-to-noise ratio,and single carrier system with TDC-CD achieves 2d B BER gain at 10~(-4).

关键词： TDC-CD transform domain GHC system diversity order

Sema 4D/CDlOO-plexin B is a multifunctiona counter-receptor

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Cellular & Molecular Immunology 2013年第2期10卷 97-98页

作者： yusi zhang Bei Liu Ying Ma Boquan Jin Department of Immunolosy The Fourth MilitaryMedical University Xi'an China

The discovery of Sema 4D can be dated to 1992, when Boumsell＇s teamreported a novel 150-kDa glycoprotein dimer. It was expressed on T lymphocytes that had been activated with CD3 mono- donal antibody or phytohaemagglutinin.1 Hence, this molecule has been designated CD100 by the International Workshop on Human Leukocyte Differentiation Antigen. In 1996, 3 years after the discovery of the semaphorin family,2 the CD100 gene was cloned and identified as the first sema- phorin with immune system functions.3 Unlike the prototypical semaphorins, which are neuronal chemorepellents, Sema 4D/ CD100 together with Sema 3A, Sema 4A,

关键词： SEMA 白细胞分化抗原受体免疫系统功能植物血凝素 T淋巴细胞二聚体糖蛋白

The prospects for Higher Vocational computer Education in the development of information technology age

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International Journal of Technology Management 2013年第3期 84-87页

作者： yusi zhang Liu Liu Tiyong zhang Hebei Jiaotong Vocational& Technical College ShijiazhuangHebeiChina

Computer technology is one of the main technologies of the information society, the development of computer education satisfies for requirements to science, the world and the future, and it is an important part of students＇ quality education, it is of great significance to improve the scientific and cultural level of the students, to promote the teaching content modernization of education and teaching reform, to improve the quality of education and the level of management.

关键词： Higher Vocational Computer Education Information Technology Age

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六壬式盘天盘布局问题补议

出土文献 2022年第3期 76-98,156,157页

作者：张雨丝复旦大学历史学系

本文以汉魏南北朝时代出土六壬式天盘为中心,结合传世占经讨论其布局及诸元素的意义。战国秦汉流行的日躔安排是六壬式运作的共同线索,“寅正”是其共同的历法背景。汝阴侯墓六壬式盘是这种日躔安排的直观表现,但因为式占需要,天盘上的... 详细信息

本文以汉魏南北朝时代出土六壬式天盘为中心,结合传世占经讨论其布局及诸元素的意义。战国秦汉流行的日躔安排是六壬式运作的共同线索,“寅正”是其共同的历法背景。汝阴侯墓六壬式盘是这种日躔安排的直观表现,但因为式占需要,天盘上的二十八宿又发展出了不同分布方式,这造成了其他六壬式天盘与通行日躔安排间的“错位”现象;《黄帝龙首经·占月宿何星法》则体现出人们试图在“新”道具上恢复“旧”秩序的努力。六壬式之创制以天共斗左旋、日顺宿右旋的图式为背景,但出土六壬式天盘上常见的北斗、二十八宿在大多数情况下并不参与式占推算,它们在天盘上的意义,更多地是作为天道秩序的象征,也有便于在其上演算其他式占的可能。

关键词：六壬式盘日躔北斗二十八宿

广义加权分数傅里叶变换两分量组合抗衰落技术

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哈尔滨工业大学学报 2020年第10期52卷 111-118页

作者：马聪沙学军张宇思哈尔滨工业大学通信技术研究所哈尔滨150001 通信网信息传输与分发技术重点实验室石家庄050081 专用通信系统教育部工程研究中心哈尔滨150001

为了在不改变载波体制的情况下,提升传统单载波(Single Carrier,SC)和多载波系统(Multi-Carrier,MC)的抗衰落能力,本文利用广义混合载波(Generalized Hybrid Carrier,GHC)系统在信号设计方面的高灵活性,提出基于广义加权分数傅里叶变换(... 详细信息

为了在不改变载波体制的情况下,提升传统单载波(Single Carrier,SC)和多载波系统(Multi-Carrier,MC)的抗衰落能力,本文利用广义混合载波(Generalized Hybrid Carrier,GHC)系统在信号设计方面的高灵活性,提出基于广义加权分数傅里叶变换(Generalized Weighted Fractional Fourier Transform,GWFRFT)的两分量组合抗衰落方案.针对SC系统,所提两分量方案包含时域和时域反转两个分量,可以有效提升系统抗时间选择性衰落的能力;针对MC系统,所提两分量方案由频域和频域反转两个分量组成,能够有效提升系统抗频率选择性衰落的能力.为了充分挖掘两分量组合信号的潜力,本文对这种信号形式获得性能优势的机理进行了分析.分析结果表明,两分量之间的功率分配和同一符号在两分量中所经历衰落的独立性是影响两分量信号性能的关键因素.鉴于此,本文提出两分量等功率设计和半码块反转方案,进一步优化了两分量组合信号的性能.在此基础上,本文给出两分量组合信号生成方法,并分析其实现复杂度和频谱特性.仿真结果表明,两分量组合方案可以在不占用额外时间和频谱资源的前提下,实现对传统SC和MC系统抗衰落性能的有效提升,而基于分量等功率分配和半码块反转的优化可以进一步增强这种性能提升的效果.

关键词：广义加权分数傅里叶变换单载波系统多载波系统两分量组合抗衰落半码块反转

基于计算机技术镁/铝合金FSW接头寿命预测

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热加工工艺 2013年第13期42卷 197-199页

作者：侯艳张于思河北交通职业技术学院河北石家庄050035

采用不同的摩擦头搅拌速度、焊接速度和单位长度上的旋转次数进行AZ91D镁合金和6061铝合金的搅拌摩擦焊,获得表征焊接接头寿命的指标数据;并将其作为计算机预测模型的训练样本和验证样本,构建了两种预测模型进行试验。结果表明,3×12×... 详细信息

采用不同的摩擦头搅拌速度、焊接速度和单位长度上的旋转次数进行AZ91D镁合金和6061铝合金的搅拌摩擦焊,获得表征焊接接头寿命的指标数据;并将其作为计算机预测模型的训练样本和验证样本,构建了两种预测模型进行试验。结果表明,3×12×2三层结构模型的训练误差过大无法满足试验要求,3×12×8×2四层结构预测模型的训练误差和预测误差均较小,预测精度较高,具有较大的实用价值。

关键词：搅拌摩擦焊接头寿命计算机预测镁铝合金

Sustained High Levels of Both Total and High Molecular Weight Adiponectin in Plasma during the Convalescent Phase of Haemorrhagic Fever with Renal Syndrome Are Associated with Disease Severity

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Sustained High Levels of Both Total and High Molecular Weigh...

HLA-E-restricted Hantaan virus-specific CD8^(+)T cell responses enhance the control of infection in hemorrhagic fever with renal syndrome

第十一届全国免疫学学术大会

作者： Tang Kang zhang Chunmei zhang yusi zhang Yun Zhuang Ran Jin Boquan Ma Ying Department of Immunology The Fourth Military Medical University

Purpose: Hantaan virus(HTNV) infection can cause haemorrhagic fever with renal syndrome(HFRS) in humans, which is characterised by an uncontrolled immune response that causes vascular leakage. Adiponectin(APN) is an adipocytokine derived mainly from adipocytes and involved in pro-revascularisation and immunomodulation. The aim of this study was to investigate the possible effects of APN in the pathogenesis of ***: The total and high molecular weight(HMW) APN levels in the plasma of patients with HFRS were quantified by enzyme-linked immunosorbent assay(ELISA). The significance of the differences between different groups was determined by the Mann–Whitney U test. The correlation of the total and HMW APN levels with clinical parameters was analyzed by nonparametric Spearman correlation ***: Compared with healthy controls, the plasma total and high molecular weight(HMW) APN levels in patients were elevated to different degrees from the fever onset and remained high at the convalescent phase. Consistant withthese results, Western blot analysis additionally showed that low molecular weight(LMW), middle molecular weight(MMW) and HMW APN levels were all elevated and contributed to the elevation of the total APN level. Importantly, sustained high levels of total and HMW APN at the convalescence phase were significantly higher in patients with critical disease than in patients with mild or moderate disease. Moreover, total and HMW APN levels negatively correlated with white blood cell count and positively correlated with platelet count and serum albumin ***: The sustained high levels of total and HMW APN in the plasma during the convalescent phase were associated with the disease severity. These results may provide insights into understanding the roles of total and HMW APN in the pathogenesis of HFRS and the cross-talk between adipocytes and the immune system after viral infection.

关键词： HFRS adiponectin revascularisation immunomodulation

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Biosafety and Health 2023年第5期5卷 289-299页

作者： Kang Tang yusi zhang Xinyu Li Chunmei zhang Xiaozhou Jia Haifeng Hu Lihua Chen Ran Zhuang Yun zhang Boquan Jin Ying Ma Department of Immunology The Fourth Military Medical UniversityXi’an 710032China Eighth Hospital of Xi’an Xi’an 710061China Department of Infectious Diseases Tangdu HospitalThe Fourth Military Medical UniversityXi’an 710038China

Infection with the Hantaan virus(HTNV)may result in severe hemorrhagic fever with renal syndrome(HFRS).The functions of HLA-E-restricted CD8^(+)T lymphocytes in virus control and vaccine development have recently received increased *** purpose of this research is to discover HLA-E-restricted CD8^(+)T cell epitopes on HTNV as well as the features of these epitope-specific CD8^(+)T cells in HFRS *** anticipate HLA-Erestricted HTNV epitopes,the NetMHCpan servers were *** K562/HLA-E cell binding test and the enzyme-linked immunospot assay were used to confirm epitope binding to *** number and features of HLA-E-restricted epitope-specific CD8^(+)T lymphocytes in HFRS patients were investigated using tetramer staining,intracellular cytokine labeling,proliferation,and cytotoxicity *** HTNV-derived HLA-Erestricted CD8^(+)T cell epitopes were found in this *** mild/moderate HFRS patients,the frequency of HLA-E-restricted epitope-specific CD8^(+)T cells was greater than in severe/critical ***38+HLA-DR+HLA-E-restricted CD8^(+)T cells were ***,CD45RA^(+)CCR7^(-)effector memory-re-expressing CD45RA T cells with early and intermediate maturation and differentiation characteristics ***,CD8^(+)T cells from milder HFRS patients produced more interferon-γ,interleukin-2,and granzyme B,had a stronger proliferative potential,and were inversely linked with the amount of plasma HTNV virus ***,HLA-E-restricted epitope-specific CD8^(+)T cells demonstrated improved cytotoxic activity in vitro during the acute stage of *** together,the findings demonstrate the protective effects of HLA-E-restricted CD8^(+)T cells during HTNV infection,suggesting that HLA-E-targeted vaccines against HTNV might be developed for HLA-diverse populations.

关键词： Hantaan virus Hemorrhagic fever with renal syndrome HLA‐E CD8+T cells Epitope

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脂连蛋白与慢性乙型肝炎病毒感染的研究进展

细胞与分子免疫学杂志 2020年第6期36卷 555-560页

作者：刘蓓张宇丝西安医学院医学技术学院陕西西安710021 空军军医大学基础医学院免疫学教研室陕西西安710032

脂连蛋白(APN)是由脂肪细胞分泌的一种重要的脂肪因子,在调节肝脏糖、脂代谢中发挥关键作用。APN与多种肝病关系密切,但关于APN与HBV慢性感染的关系,以及APN在HBV慢性感染疾病进展中的作用仍有争议。细胞实验和动物实验表明,APN能够通... 详细信息

脂连蛋白(APN)是由脂肪细胞分泌的一种重要的脂肪因子,在调节肝脏糖、脂代谢中发挥关键作用。APN与多种肝病关系密切,但关于APN与HBV慢性感染的关系,以及APN在HBV慢性感染疾病进展中的作用仍有争议。细胞实验和动物实验表明,APN能够通过调节肝星状细胞(HSC)的激活和抑制炎症反应发挥抗肝纤维化作用,对肝损伤发挥保护作用。而APN水平在HBV慢性感染患者中较健康对照显著升高,随肝纤维化程度加重而升高,HBV相关肝硬化、肝癌患者APN水平显著升高。APN作为HBV感染者肝纤维化程度诊断指标的可行性还有待进一步研究。高APN可能能作为一种辅助诊断HBV相关肝硬化的标志物。

关键词：脂连蛋白(APN) 肝脏乙型肝炎病毒综述