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Acta Mechanica Sinica 2011年第1期27卷 68-71页

作者： Igor v.Andrianov yurii A.Kirichek Jan Awrejcewicz Institute of General Mechanics RWTH Aachen University Prydniprovskaya State Academy of Civil Engineeringand Architecture Department of Automation and Biomechanics Technical University of Lódz

A frequency equation for the vibration of an engine seating and an equation for pressure under the bottom of the engine are *** present approach extends the so called Muravskii model possessing high practical accuracy... 详细信息

关键词： Elastic foundation · vibration · Boundary value problems

Activating Effect of Staphylococcal Enterotoxins

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Advances in Microbiology 2024年第3期14卷 175-181页

作者： yurii v. Ezepchuk Aurora USA

The effect of enterotoxins is to induce the production of endogenous IF. St. aureus enteropathogenic proteins (enterotoxins) possess an antitumour effect. After intraperitoneal inoculation, they decrease the size and, in some cases, prevent the development of the human hypernephroma in the cheek pouch of golden hamsters. The effect of enteropathgenic proteims may possibly consist in inducing the production of endogenous immune interferon which activates the host immune system and enhances the rejection of heterologous tumour cells.

关键词： Gamma-Interferon Enterotoxins Antitumour Activity

Biological Concept of Bacterial Pathogenicity (Theoretical Review)

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Advances in Microbiology 2017年第7期7卷 535-544页

作者： yurii v. Ezepchuk 2937 South Revere St. Aurora CO USA

Biological nature of the bacterial pathogenicity phenomenon is based on the interaction of prokaryotic and eukaryotic organisms. The phenomenon is the poly-functional biological potency of germs that are realized by factors (determinants) of pathogenicity. Some fundamental biological functions are responsible for bacterial pathogenicity in a multi-cellular host organism: the adhesive function, the function of invasion and penetration into the cell, the function of evasion of host defense, and the damage function. The action of adhesion, invasion and evasionis directed to towards establishing an ecological niche in multi-cellular host while the aim of the damaging function is destruction of the environment.

关键词： Bacterial Pathogenicity Biological Function “Pathogenicity Islands” Infectious Diseases Prokaryotic and Eukaryotic Organisms

Modification of titanium surface via Ag-,Sr-and Si-containing micro-arc calcium phosphate coating

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Bioactive Materials 2019年第1期4卷 224-235页

作者： Mariya B.Sedelnikova Ekaterina G.Komarova yurii P.Sharkeev Anna v.Ugodchikova Tatiana v.Tolkacheva Julietta v.Rau Evgeny E.Buyko vladimir v.Ivanov vladimir v.Sheikin Institute of Strength Physics and Materials Science of SB RAS Academicheskii Prospect 2/4Tomsk634055Russia National Research Tomsk Polytechnic University Lenina Prospect 30Tomsk634050Russia Istituto di Struttura della Materia Consiglio Nazionale delle Ricerche(ISM-CNR)Via del Fosso del Cavaliere 10000133 RomaItaly Siberian State Medical University Moscovskii Tract 2Tomsk634050Russia

The current research is devoted to the study of the modification of the titanium implants by the micro-arc oxidation with bioactive calcium phosphate coatings containing Ag or Sr and Si *** coatings’microstructure,phase composition,morphology,physicochemical and biological properties were examined by scanning electron microscopy(SEM),transmission electron microscopy(TEM),energy-dispersive X-ray spectroscopy(EDX)and X-ray diffraction(XRD).Ag-containing and Sr-Si-incorporated coatings were formed in alkaline and acid electrolytes,*** formation of the coatings occurred at different ranges of the applied voltages,which led to the significant difference in the coatings *** trace elements Ag,Sr and Si participated intensively in the plasma-chemical reactions of the micro-arc coatings ***-containing coatings demonstrated strong antibacterial effect against Staphylococcus aureus AТСС*** in vitro test with 3T3-L1 fibroblasts showed no cytotoxicity appearance on Sr-Si-incorporated coatings.

关键词： Trace elements Biocoatings Micro-arc oxidation Titanium substrate Antibacterial activity

World cities in terms of the sustainable development concept

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Geography and Sustainability 2021年第4期2卷 304-311页

作者： Kostiantyn Niemets Kateryna Kravchenko yurii Kandyba Pavlo Kobylin Cezar Morar Department of Human Geography and Regional Studies Faculty of GeologyGeographyRecreation and TourismV.N.Karazin Kharkiv National UniversitySvobody Sq.4Kharkiv 61022Ukraine Department of Geography Tourism and Territorial PlanningFaculty of GeographyTourismand SportUniversity of OradeaUniversity St.C.Hall Office 221Oradea 410087Romania

The article considers the issue of the world cities in terms of sustainable *** population has been increasing in such intensive rates never reached during the middle of the 20th *** expansion of the cities indicates,on the one hand,the growth of the world’s general socio-economic development,on the other hand,it raises a number of economic,social and environmental *** purpose of this paper is to analyze the current state and prospects of the world cities in terms of the sustainable development concept,to identify opportunities,threats,strengths and weaknesses of the world cities,to determine the role of cities in the con-temporary global world and consider further research of the world’s *** authors analyzed the world cities rankings and noted that highly developed cities have more chances to quickly implement the sustainable devel-opment concept compared to medium-sized cities due to larger financial *** authors built a SWOT analysis of the world cities transformation in terms of the sustainable development concept,identified strengths,weaknesses,opportunities and *** to the results of the SWOT analysis,the authors established that sustainable development of cities requires significant investments,particularly in the social sphere develop-ment,purification,and preservation of urban nature from the anthropogenic *** research result is the systematization of the sustainable development criteria used in compiling the world cities rankings,determining the possibilities of the contemporary cities transition to the sustainable development concept.

关键词： World cities Sustainable development Ranking Eco-city Smart city Sustainable city

Efficiency of high-loaded nickel catalysts modified by Mg in hydrogen storage/extraction using quinoline/decahydroquinoline pair as LOHC substrates

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Journal of Magnesium and Alloys 2024年第8期12卷 3245-3263页

作者： Anton P.Koskin Jingsong Zhang Olga B.Belskaya Olga A.Bulavchenko Darya A.Konovalova Sergey A.Stepanenko Arkadiy v.Ishchenko Irina G.Danilova vyacheslav L.Yurpalov yurii v.Larichev Roman G.Kukushkin Petr M.Yeletsky Federal Research Center Boreskov Institute of Catalysis SB RAS Acad.Lavrentiev av.5Novosibirsk630090Russian Federation Center of New Chemical Technologies BIC Boreskov Institute of CatalysisNeftezavodskaya st.54Omsk 644040Russia

An effect of Mg introduction on efficiency of high-loaded nickel catalysts in dehydrogenation of decahydroquinoline(10HQ)was inves-tigated.10HQ dehydrogenation is key process for the liquid organic hydrogen carrier(LOHC)storage technology using the quinoline/10HQ pair as H_(2)-lean/H_(2)-rich *** influence of synthesis technique of Ni/Mg/Al catalysts on their properties has been *** catalysts were synthesized through coprecipitation of Ni,Mg,Al precursors to obtain layered double hydroxides(LDH)or via syn-thesis of(∼72 wt%)Ni-Al_(2)O_(3) system-also through coprecipitation,followed by modifying with a magnesium-containing *** the catalysts of the first series,the inclusion of magnesium into LDH lattice led to a significant increase in catalytic activity in hydrogen extraction(10HQ dehydrogenation reaction).Despite the decrease in the content of catalytically active nickel,a significant increase in the yield of the dehydrogenation product was *** regularity is presumably associated with appearance of basic sites,that accelerates the dehydrogenation *** the case of the second series,activity of pre-reduced(600°C,H_(2))catalysts in dehydrogenation of 10HQ also significantly depends on a MgO content and is maximal at Mg:Ni weight ratio *** an in-depth study of structure of the original and reduced catalyst samples(Ni-Al_(2)O_(3) and Ni-MgNiOx-Al_(2)O_(3)),it was shown that this regularity is associated with the increased resistance of catalytically active Ni particles to agglomeration during the reductive ***,using the Ni-MgNiOx-Al_(2)O_(3)catalyst for hydrogen storage process(hydrogenation reaction),the possibility of deep quinoline hydrogenation(up to 10HQ)in a flow-type reactor was demonstrated for the first time.

关键词： Mg-modified catalysts High-loaded nickel catalyst Layered double hydroxides Hydrogen storage LOHC Dehydrogenation

Human chemerin induces eryptosis at concentrations exceeding circulating levels

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BIOCELL 2024年第8期48卷 1197-1208页

作者： MARYNA TKACHENKO ANATOLII ONISHCHENKO LILIYA TRYFONYUK DMYTRO BUTOv KATERYNA KOT vIKTORIIA NOvIKOvA LIWEI FAN vOLODYMYR PROKOPIUK yurii KOT ANTON TKACHENKO Department of Internal Medicine No.2 Clinical Immunology and AllergologyKharkiv National Medical UniversityKharkiv61022Ukraine Research Institute of Experimental and Clinical Medicine Kharkiv National Medical UniversityKharkiv61022Ukraine Institute of Health National University of Water and Environmental EngineeringRivne61022Ukraine Department of Infectious Diseases and Phthisiology Kharkiv National Medical UniversityKharkiv61022Ukraine Biochemistry Department V.N.Karazin Kharkiv National University Ministry of Education and Science of UkraineKharkiv61022Ukraine Department of Chemistry BiochemistryMicrobiology and Food HygieneState Biotechnological UniversityKharkiv61022Ukraine Clinical Research Innovation Lab Floor 26 Block D Qidi Technology Building 8Tsinghua Technology ParkBeijing100084China Department of Cryobiochemistry Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of UkraineKharkiv61015Ukraine

Introduction:Human chemerin is an adipokine that regulates chemotaxis,inflammation,and glucose *** addition,accumulating evidence suggests that chemerin promotes apoptosis,autophagy,and ***,there are no data on its impact on *** current study aimed to analyze the effects of human active Glu^(21)-Ser^(157) chemerin on eryptosis in *** and Methods:Human chemerin 0-2-10-50μg/mL was incubated for 24 h with human erythrocytes(hematocrit 0.4%)obtained from eight healthy *** cytometry-based determination of phospholipid scrambling,reactive oxygen species(ROS)production,and intracellular Ca^(2+)levels was *** supplement data on ROS and Ca^(2+)signaling in chemerin-mediated eryptosis,incubation in the presence or absence of antioxidants vitamin C and N-acetylcysteine and Ca^(2+)-binding agent EGTA was carried out,*** microscopy-based techniques were used to detect reactive nitrogen species(RNS)generation,involvement of caspase-3 and caspase-8,as well as the state of lipid order in cell membranes of erythrocytes exposed to human Glu^(21)-Ser^(157) ***:Our observations suggest that human Glu^(21)-Ser^(157) chemerin had no impact on eryptosis parameters at 2μg/***,chemerin stimulated phosphatidylserine externalization,ROS production,and Ca^(2+)accumulation at higher concentrations suggesting activation of ***^(2+)uptake turned out to be at least partly required for chemerin-mediated ***-mediated erythrotoxicity was additionally mediated by RNS,caspase-3,and ***,Glu^(21)-Ser^(157) chemerin promoted reduction in the liquid-ordered phase of cell membranes in ***:The present study first discloses that human chemerin can induce eryptosis via Ca^(2+)-dependent mechanisms at concentrations noticeably exceeding circulating ***,chemerin-induced eryptosis can hardly contribute to eryptosis-mediated anemia in disease

关键词： Adipokine Cell death Chemerin Oxidative stress Eryptosis

Liver resection for early hepatocellular cancer: Comparison of centers in 3 different countries

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World Journal of Hepatology 2016年第31期8卷 1327-1335页

作者： Linda L Wong Brenda Y Hernandez yurii B Shvetsov Yoichi Kawano Zhao-You Tang Jun-Fang Ji Cancer Center Department of Surgery John A Burns School of MedicineUniversity of Hawaii Department of Surgery Nippon Medical School Liver Cancer Institute and Zhongshan Hospital Fudan University Life Sciences Institute Zhejiang University

AIMTo compare patients who underwent resection of early stage hepatocellular cancer (HCC) in three different countries. METHODSThis retrospective study characterizes 573 stage I/II HCC patients treated with liver resection in 3 tertiary-referral centers: Tokyo (n = 250), Honolulu (n = 146) and Shanghai (n = 177). RESULTSShanghai patients were younger, predominantly male, hepatitis-B seropositive (94%) and cirrhotic (93%). Tokyo patients were older and more likely to have hepatitis-C (67%), smaller tumors, low albumin, and normal alpha-fetoprotein. The Honolulu cohort had the largest tumors and 30% had no viral hepatitis. Age-adjusted mortality at 1 and 5-years were lower in the Tokyo cohort compared to Honolulu and there was no difference in mortality between Shanghai and Honolulu cohorts. Elevated alpha-fetoprotein, low albumin and tumor > 5 cm were associated with increased 1-year mortality. These factors and cirrhosis were independently associated with increased 5-year mortality. Independent risk factors of survival varied when examined separately by center. CONCLUSIONThe profile of early-stage HCC patients is strikingly different across countries and likely contributes to survival differences. Underlying differences in patient populations including risk factors/comorbidities influencing disease progression may also account for variation in outcomes.

关键词： Hepatocellular cancer Liver resection viral hepatitis

Gravity observation at continental borderlands (Russia, Primorie, Cape Shults)

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Geodesy and Geodynamics 2017年第3期8卷 193-200页

作者： vladimir Yu. Timofeev Eugenii N. Kalish Dmitriy G. Ardyukov Maksim G. valitov Anton v. Timofeev yurii F. Stus Ruslan G. Kulinich Dmitrii A. Nosov Igor S. Sizikov Bernard Ducarme Trofimuk Institute of Petroleum Geology and Geophysics of Siberian Branch Russian Academy of Sciences 630090 Novosibirsk Akademika Koptyuga Prsp..3 Russian Federation Institute of Automatic and Electrometry of Siberian Branch Russian Academy of Sciences 630090 Novosibirsk Akademika Koptyuga Prsp. 1 Russian Federation Il'ichev Pacific Oceanological Institute Far Eastern Branch of Russian Academy of Science 690041 Vladivostok Baltivskayast. 43 Russian Federation Georges Lemaotre Centre for Earth and Climate Research. Catholic University of Louvain Leuven Belgium

The paper is focused on different kinds of gravity results obtained in Shults Cape Observatory for 2010 -2015. Gravity observation is interpreted together with GPS observation data which was obtained from 2012 to 2015 at the same station, The station is situated on Gamov peninsular （42.58° N, 131.15° E, Russia） at the coast of Japan Sea, This region constitutes the eastern boundary of Eurasia. This major continental tectonic feature is associated with a seismic activity, high heat flow and anomalous thickness of earth＇s crust. The goal of the observation was the investigation of gravity variation with time and seismicity situation monitoring. Gravity observation was developed at special basement by absolute gravimeter （GABL type） and by spring gravimeter （SCINREX CG-5and gPhone type）. Tidal models were tested by results of observation with spring gravimeters. Reduction task was solved, as the experimental data received from different points of Shults Cape Observatory was used. Applied reduction coefficient is 203.3 12Gal m l, and agrees with theoretical calculation. Next goal was studying structure of earth＇s crust by means of gravity models. Gravity anomaly varied from 30 mGal to 46 mGal, which also depend on difference reference system, Experimental results were used for testing of the structure of continental boundary, which also depends on the sea bottom flexion. Thickness of elastic layer was estimated from 12 km to 18 km by using different models.

关键词： Absolute and relative gravity observation Space geodesy Reduction task for gravity Structure models Crust