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现代日语口语和歌曲中的音节发音比较研究--以「す」「つ」的元音无声化现象为例

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文化创新比较研究 2021年第27期5卷 123-128页

作者：高宇青李香扬州大学日语系江苏扬州225009

现代日语口语和歌曲中的音节发音存在着一定的差异,比如,假名音节「す」「つ」在口语中应当发生元音无声化的地方,在歌曲中却常常不出现无声化现象。针对这一现象,通过语音学软件Praat,将语音信号数字化并对其进行分析,证实了这些差异... 详细信息

现代日语口语和歌曲中的音节发音存在着一定的差异,比如,假名音节「す」「つ」在口语中应当发生元音无声化的地方,在歌曲中却常常不出现无声化现象。针对这一现象,通过语音学软件Praat,将语音信号数字化并对其进行分析,证实了这些差异的存在及其表现形式。其可能原因可以从语言学与声乐学两个角度解释:发音速度对元音无声化发生的概率有较大影响;歌曲的旋律变化代替了原本口语中发音的声调变化,声调核不再存在;口语发音与歌唱时的发音特点存在差异以及歌手的个性化处理。

关键词：现代日语歌曲元音无声化口语 Praat

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普贝生在足月妊娠引产中的临床应用

江苏医药 2012年第8期38卷 941-942页

作者：高玉青周口市中心医院妇产科河南省466000

目的探讨普贝生(propess)用于足月妊娠引产的有效性和安全性。方法将100例初产妇随机分两组,每组50例。A组阴道内放置普贝生1枚,B组阴道内放置安慰剂作为对照。比较两组用药后宫颈Bishop评分、用药到临产发动时间、总产程、产后出血量... 详细信息

目的探讨普贝生(propess)用于足月妊娠引产的有效性和安全性。方法将100例初产妇随机分两组,每组50例。A组阴道内放置普贝生1枚,B组阴道内放置安慰剂作为对照。比较两组用药后宫颈Bishop评分、用药到临产发动时间、总产程、产后出血量、剖宫产率、胎儿宫内窘迫及新生儿窒息率。结果 A组用药12h的有效率(宫颈评分提高≥2分)明显高于B组(92%vs.12%)(P<0.05),用药到临产发动时间[(19.2±2.5)h vs.(52.3±3.2)h]、总产程时间[(8.6±2.1)hvs.(14.3±4.6)h]亦明显短于对B组(P<0.05),阴道分娩率增加(84%vs.52%),剖宫产率降低(16%vs.48%)。两组产后出血量、胎儿宫内窘迫及新生儿窒息率无统计学差异。结论普贝生能有效促进宫颈成熟,可安全用于引产。

关键词：普贝生引产

Transcriptomic and metabolomic analysis of changes in grain weight potential induced by water stress in wheat

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Journal of Integrative Agriculture 2024年第11期23卷 3706-3722页

作者： Yanmei gao Maoya Jing Meng Zhang Zhen Zhang yuqing Liu Zhimin Wang Yinghua Zhang School of Life Science Shanxi Normal University Ministerial and Provincial Co-Innovation Centre for Endemic Crops Production with High-quality and Efficiency in Loess Plateau College of Agronomy and Biotechnology China Agricultural University

The sink strength of developing ovaries in wheat determines the grain weight potential. The period from booting to the grain setting stage is critical for ovary growth and development and potential sink capacity ***, the underlying regulatory mechanism during this period by which the wheat plant balances and coordinates the floret number and ovary/grain weight under water stress has not been clarified. Therefore, we designed two irrigation treatments of W0(no seasonal irrigation) and W1(additional 75 mm of irrigation at the jointing stage) and analyzed the responses of the ovary/grain weight to water stress at the phenotypic, metabolomic, and transcriptomic levels. The results showed that the W0 irrigation treatment reduced the soil water content, plant height, and green area of the flag leaf, thus reducing grain number, especially for the inferior grains. However, it improved the grain weight of the superior and inferior grains as well as average grain weight at maturity, while the average ovary/grain weight and volume during –3 to 10 days after anthesis(DAA) also increased. Transcriptomic analysis indicated that the genes involved in both sucrose metabolism and phytohormone signal transduction were prominently accelerated by the W0 treatment, accompanied by greater enzymatic activities of soluble acid invertase(SAI) and sucrose synthase(Sus) and elevated abscisic acid(ABA) and indole-3-acetic acid(IAA) levels. Thus, the sucrose content decreased, while the glucose and fructose contents increased. In addition, several TaTPP genes(especially TaTPP-6) were down-regulated and the IAA biosynthesis genes TaTAR1 and TaTAR2 were up-regulated under the W0 treatment before anthesis, which further increased the IAA level. Collectively, water stress reduced the growth of vegetative organs and eliminated most of the inferior grains, but increased the ABA and IAA levels of the surviving ovaries/grains, promoting the enzymatic activity of Sus and degrading sucr

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踝关节外骨骼人机耦合动力学与助力性能分析

力学学报 2022年第12期54卷 3496-3512页

作者：高钰清靳葳徐鉴方虹斌复旦大学智能机器人研究院上海200433 复旦大学智能机器人教育部工程研究中心上海200433 复旦大学上海智能机器人工程技术研究中心上海200433

踝关节在人体下肢运动过程中提供了最大的关节力矩,因此在下肢增强型外骨骼的研究中,踝关节外骨骼受到了重点关注.穿戴外骨骼的人体的行走是典型的动力学问题,但目前人机耦合动力学的相关研究还处于早期阶段.本文以绳驱踝关节外骨骼为... 详细信息

踝关节在人体下肢运动过程中提供了最大的关节力矩,因此在下肢增强型外骨骼的研究中,踝关节外骨骼受到了重点关注.穿戴外骨骼的人体的行走是典型的动力学问题,但目前人机耦合动力学的相关研究还处于早期阶段.本文以绳驱踝关节外骨骼为研究对象,融合机器人正运动学方法和拉格朗日方程建立了考虑足-地交互力、人体关节力矩和外骨骼力矩的人-机耦合动力学模型.模型中,足-地交互力由Kelvin-Voigt模型结合库伦摩擦模型描述,人体关节力矩由基于粒子群优化的PD控制生成,外骨骼期望力矩由上层控制器依据人体步态周期确定.通过基于模型的动力学仿真,本文从人体踝关节角度、踝关节力矩、踝关节功率和踝关节做功多个角度系统分析了踝关节外骨骼对人体行走的助力效果.研究表明,在2.0 km/h到6.5 km/h的人体步行速度下,穿戴外骨骼可以实现至少24.84%的人体踝关节平均力矩下降和至少24.69%的踝关节做功下降.本文也开展了基于SCONE平台的肌肉骨骼建模和预测仿真.仿真结果表明,在3.6 km/h的步行速度下,穿戴外骨骼可以有效降低比目鱼肌的激活度峰值,并使肌电信号的RMS值下降了6.21%,从而从生理学的角度证实了踝关节外骨骼的助力效果.本文的结果进一步完善了人体下肢-外骨骼耦合系统的动力学建模和分析方法,从动力学和生理学角度证实和解释了踝关节外骨骼对行走的助力机制,也为今后下肢外骨骼的实验研究提供了理论支撑.

关键词：下肢动力外骨骼动力学建模人机动力学肌肉骨骼模型肌肉激活度

Occurrence of fludioxonil resistance in Botrytis cinerea from greenhouse tomato in China

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Occurrence of fludioxonil resistance in Botrytis cinerea fro...

Clinical observation of continuously subcutaneous-pumped octreotide infusion in palliative treatment of malignant bowel obstruction

中国植物病理学会2019年学术年会

作者： Zhou Feng Song Yulu Li Shuai gao yuqing Ruan Kang Fan Yuchuang Guo Hanxue Li Chengwei College of Resources ＆ Environmental Science Henan Institute of Science and Technology Henan Engineering Research Center of Crop Genome Editing

Gray mold caused by the fungus Botrytis cinerea is one of the most important diseases *** has high activity against ***,and it has been reported that resistant mutants of *** emerged in some regions due to its multi-frequency and unscientific *** at 5μg/mL was used as a discriminatory dose to detect resistance in candidate isolates,and 50% effective concentration values were determined for all fludioxonil-resistant isolates and some sensitive *** high level field-fludioxonil-resistant isolate was *** with the sensitive isolates of ***,the resistant isolate was more sensitive to osmotic pressure,glycerol content significantly higher and less pathogenic on detached leaves of tomato and *** analysis indicated that two amino acid sites mutations at the（Histidine kinases,Adenylyl cyclases,Methy binding proteins,Phosphatases;HAMP） HAMP domain of（Histidine Kinase,HK） HK（BcOsl） in field fludioxonilresistant isolate,and the HAMP domain of HK is necessary to recognizing the stimulation from the compounds,the two mutations in this domain may be related to the fludioxonil-resistance in *** results will reveal the molecular mechanism of the function of HAMP domain of Bcosl in fludioxonil-resistance in ***,and these studies have important theoretical and practical significance for the development of new fungicides and fludioxonil-resistance management strategies.

关键词： Fludioxonil Resistance mechanism Botrytis cinerea Bcos1 Biological characteristics

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The Chinese-German Journal of Clinical Oncology 2011年第1期10卷 31-34页

作者： Dongfeng Yin Yin Zhu yuqing Xing Hong gao Yuzhen Pan Lin Pan Guangyi Tang Xiangrong Xing Lijiang Zhou Department of Internal Oncology Affiliated Hospital of Liaoning University of Traditional ChineseMedicine Shenyang 110032 China

Objective： The aim of the study was to observe the effectiveness of continuously subcutaneous-pumped octreotide infusion in palliative treatment of malignant bowel obstruction （MBO）. Methods： Clinical data were retrospectively analyzed in 26 carcinoma patients complicated with MBO, in the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, China, from March 2007 to April 2009. All 26 carcinoma patients with MBO were divided into no groups： the controlling group （CG, routine therapy, 15 patients） and the octreotide group （OG, 11 patients）. The octreotide group received routine therapy combined with octreotide （0.3 mg/d） by 24 hours continuously subcutaneous octreotide infusion. The changes of curative effectiveness related to symptoms, the times of recovering exsufflation and defecation, the average drain of gastrointestinal drainage tube, the duration of gastrointestinal drainage tube and the rate of extubation, were observed and compared between the two groups. Results： After treatment, remarkable changing rates of MBO related symptoms were 81.8% （9/11） in OG, and 46.7% （7/15） in CG （P 〈 0.05）. The 78% of SG and 30% of CG recovered the exsufflation and defecation, and the mean times they needed were 3.2 d and 5.8 d, respectively （P 〈 0.05）. The durations of gastrointestinal drainage tube of OG and CG were （5 ± 1.2） d and （10 ±2.3） d, respectively, and the rates of extubation were 54.5% and 20%, respectively. The improvement rate in the octreotide group was better than that in the controlling group and the difference was significant （72.7% and 26.7%, P 〈 0.05）. Conclusion; The administration of octreotide in combination with routine treatment can be very effective in the treatment of MBO. It can relieve the symptoms of MBO effectively and improve the quality of life of the end-stage patients. It has provided one kind of new treating thought and method for treatment of malignant bowel obstruction.

关键词： malignant bowel obstruction (MBO) octreotide palliative treatment continuously subcutaneous-pumped infusion

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微胶囊自修复聚合物材料的发展

中国塑料 2014年第3期28卷 16-22页

作者：董金虎贺志荣高于青陕西理工学院材料科学与工程学院陕西汉中723003 陕西省新型节能环保工程中心陕西汉中723003 内蒙古中煤蒙大新能源化工有限公司内蒙古鄂尔多斯017314

对微胶囊自修复聚合物材料近年来一些新的研究进展进行了综述,包括微胶囊自修复聚合物材料技术的发展历程,荧光数字图像技术、光测弹性技术在微胶囊自修复聚合物材料研究领域的应用以及微胶囊/微血管自修复聚合物材料制备的技术要点。

关键词：聚合物微胶囊自修复

胰岛素、654-2、庆大霉素联合湿敷法治疗糖尿病足的临床探讨

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反射疗法与康复医学 2020年第2期1卷 108-109页

作者：高玉庆临沂市兰山区柳青街道社区卫生服务中心山东临沂276000

目的对胰岛素、654-2(山莨菪碱-2)、庆大霉素联合湿敷法治疗糖尿病足的临床疗效进行分析探讨.方法此次一共纳入糖尿病足患者一共80例,入选地点及时间为该院2018年1月—2019年1月,然后以随机抽样分组法分成两个不同的组别,每组平均为40例... 详细信息

目的对胰岛素、654-2(山莨菪碱-2)、庆大霉素联合湿敷法治疗糖尿病足的临床疗效进行分析探讨.方法此次一共纳入糖尿病足患者一共80例,入选地点及时间为该院2018年1月—2019年1月,然后以随机抽样分组法分成两个不同的组别,每组平均为40例;其中,对照组采取常规对症方法治疗;观察组采取胰岛素、654-2、庆大霉素联合湿敷法治疗,进一步比较两组临床治疗效果.结果观察组、对照组治疗总有效率分别为95.00%、75.00%,观察组显著要比对照组高,两组之间的数据差异有统计学意义(P<0.05).结论在临床中,对于糖尿病足患者,采取胰岛素、654-2、庆大霉素联合湿敷法治疗,疗效显著,具备采纳及使用的价值意义.

关键词：胰岛素庆大霉素湿敷法糖尿病足疗效

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深海采矿集矿机的研究与开发

矿业研究与开发 2006年第B10期26卷 52-56页

作者：丁六怀高宇清长沙矿山研究院湖南长沙410012

介绍了我国深海采矿集矿机的研制背景和研究开发历程,对我国现有深海采矿集矿机的组成与结构特点、关键技术问题及其解决情况进行了总结。对集矿机在我国深海采矿研究中的应用,及其在深海底栖工程装备方面的移植和拓展前景进行了展望。

关键词：深海采矿集矿机结构特点关键技术应用前景