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“最是书香能致远”——全民阅读推广名师徐雁的文学名著阅读观

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高校图书馆工作 2022年第1期42卷 72-76页

作者：何雨琪南京大学信息管理学院南京210023

在2018年中国全民阅读年会组委会所表彰的"全民阅读十佳推广人"中,徐雁教授是唯一一位来自高等学校的教授。多年来他以读书、评书、著书、编书和教书为主要生活方式,理论联系实际地传播书香理念,推广阅读方法。他所倡导的"深入阅读文学... 详细信息

在2018年中国全民阅读年会组委会所表彰的"全民阅读十佳推广人"中,徐雁教授是唯一一位来自高等学校的教授。多年来他以读书、评书、著书、编书和教书为主要生活方式,理论联系实际地传播书香理念,推广阅读方法。他所倡导的"深入阅读文学名著内涵、深入思考作品人物言行、深入汲取作家人生智慧"的人文阅读理念,对播撒读书种子、推动全民阅读,具有重要的现实意义。文章梳理了徐雁教授文学名著阅读观的形成过程,从阅读的价值、阅读的选择、阅读的方法以及"大阅读观"四个维度解读其内涵,并指出了其文学名著阅读观推广和传播的主要途径。

关键词：徐雁全民阅读推广文学名著大阅读观

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Enhanced extracellular production of alpha-lactalbumin from Bacillus subtilis through signal peptide and promoter screening

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Food Science and Human Wellness 2024年第4期13卷 2310-2316页

作者： yuqi Zhu Pengdong Sun Chunjian Li Yu Zhang Yu Wang Jingyuan Li Yanfeng Liu Jian Chen Yang Deng College of Food Science and Engineering Qingdao Agricultural UniversityQingdao 266109China Key Laboratory of Special Food Processing(Co-construction by Ministry and Province) Ministry of Agriculture Rural AffairsQingdao Agricultural UniversityQingdao 266109China Qingdao Special Food Research Institute Qingdao 266109China Science Center for Future Foods Engineering Research Center of Ministry of Education on Food Synthetic BiotechnologyJiangsu Province Engineering Research Center of Food Synthetic BiotechnologyJiangnan UniversityWuxi 214122China Key Laboratory of Carbohydrate Chemistry and Biotechnology Ministry of EducationSchool of BiotechnologyJiangnan UniversityWuxi 214122China

Alpha-lactalbumin(α-LA)is a major whey protein found in breast milk and plays a crucial role in the growth and development of *** this study,Bacillus subtilis RIK1285 harboring AprE signal peptide(SP)was selected as the original strain for the production ofα-*** was found thatα-LA was identified in the pellet after ultrasonic disruption and centrifugation instead of in the fermentation *** original strain most likely only producedα-LA intracellular,but not *** improve the expression and secretion ofα-LA in RIK1285,a library of 173 homologous SPs from the *** 168 genome was fused with target LALBA gene in the pBE-S vector and expressed extracellularly in *** YjcN was determined to be the best signal *** in supernatant were observed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and purified by nickel column to calculate the highest yield signal *** addition,different promoters(P_(aprE),P_(43),and P_(glv))were compared and *** results indicated that the strain RIK1285-pBE-P_(glv)-YjcN-LALBA had the highestα-LA yield,reaching 122.04μg/*** study demonstrates successful expression and secretion of humanα-LA in *** and establishes a foundation for simulating breast milk for infant formulas and developing bioengineered milk.

关键词： Bacillus subtilis Alpha-lactalbumin Bioengineering milk Signal peptide Promoter screening

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Knockout of C6orf120 in Rats Alleviates Concanavalin A-induced Autoimmune hepatitis by Regulating Macrophage Polarization

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Biomedical and Environmental Sciences 2024年第6期37卷 594-606页

作者： Xin Wang yuqi Wang Hui Liu Yingying Lin Peng Wang Yunyun Yi Xin Li Department of Center of Integrated Traditional Chinese and Western Medicine Peking University Ditan Teaching HospitalBeijing 100015China Department of Center of Integrated Traditional Chinese and Western Medicine Beijing Ditan HospitalCapital Medical UniversityBeijing 100015China Department of Center of Infectious Disease Beijing Ditan HospitalCapital Medical UniversityBeijing 100015China

Objective The effect of the functionally unknown gene C6orf120 on autoimmune hepatitis was investigated on C6orf120 knockout rats(C6orf120^(-/-))and THP-1 *** Six–eight-week-old C6orf120^(-/-)and wild-type(WT)SD rats were injected with Con A(16 mg/kg),and euthanized after 24 *** sera,livers,and spleens were ***-1 cells and the recombinant protein(rC6ORF120)were used to explore the mechanism in *** frequency of M1 and M2 macrophages was analyzed using flow *** blotting and PCR were used to detect macrophage polarization-associated *** C6orf120 knockout attenuated Con A-induced autoimmune *** cytometry indicated that the proportion of CD68^(+)CD86^(+)M1 macrophages from the liver and spleen in the C6orf120^(-/-)rats decreased.C6orf120 knockout induced downregulation of CD86 protein and the mRNA levels of related inflammatory factors TNF-α,IL-1β,and IL-6 in the liver.C6orf120 knockout did not affect the polarization of THP-1 ***,rC6ORF120 promoted the THP-1 cells toward CD68^(+)CD80^(+)M1 macrophages and inhibited the CD68^(+)CD206^(+)M2 *** C6orf120 knockout alleviates Con A-induced autoimmune hepatitis by inhibiting macrophage polarization toward M1 macrophages and reducing the expression of related inflammatory factors in C6orf120^(-/-)rats.

关键词： C6orf120 Autoimmune hepatitis Macrophage polarization M1 macrophages

Direct Analysis of Whole Blood by a Disposable Monolithic Column Mass Spectrometry Analysis Kit

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Chinese Journal of Chemistry 2024年第10期42卷 1073-1078页

作者： Wenxin Wang Jin Han Yutong Zheng Haijie Wang Chengbiao Zhu Yongyi Li yuqi Feng Zhenwei Wei Xiangyu Wang College of Chemistry and Molecular Science Wuhan UniversityWuhanHubei 430072China School of Public health Wuhan UniversityWuhanHubei 430072China Schoolof Bioengineering and health Wuhan Textile UniversityWuhanHubei 430200China

A monolithic column-based mass spectrometry(MS)analysis kit was prepared for whole blood analysis with *** kit is disposable and can be used for purification,storage,transportation and direct analysis of whole *** kit mainly consists of a capillary for quantitative microsampling,a cation exchange monolithic column for purification and storage,and a syringe for loading *** kit is very friendly to various users that one can easily siphon the blood in the kit followed by rapid *** established a quantitative method using the kit with a limit detection as low as 0.33 nmol/L,and achieved more than five orders of magnitude enhancement in sensitivity compared to direct nanoelectrospray ionization MS *** column can avoid analyte exposure to environment,which helps the storage of the sample for laboratory *** relative standard deviation of immediate blood analysis and storage blood analysis within 10 d was less than 10%.This method has been successfully applied to the quantitative analysis of procainamide hydrochloride in 2μL rat *** results indicate that this disposable kit does have the potential to achieve highly sensitive quantitative MS analysis in biological samples,which is expected to become a cost-effective and powerful tool for in vitro diagnostics.

关键词： Clinical Ms Whole blood analysis Porous polymers Matrix isolation Trace analysis

Keplerate polyoxomolybdate nanoball mediated controllable preparation of metal-doped molybdenum disulfide for electrocatalytic hydrogen evolution in acidic and alkaline media

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Chinese Chemical Letters 2024年第7期35卷 524-528页

作者： Ping Wang Ting Wang Ming Xu Ze Gao Hongyu Li Bowen Li yuqi Wang Chaoqun Qu Ming Feng Key Laboratory of Functional Materials Physics and Chemistry of the Ministry of Education Jilin Normal UniversityChangchun 130103China School of Science Changchun University of Science and TechnologyChangchun 130022China

Rationally designed novel cost-effective hydrogen evolution reaction(heR)electrocatalysts with controlled surface composition and advanced structural superiority is extremely critical to optimize the heR ***(POMs)with structural diversity and adjustable element compositions represent a promising precursor for rational design and preparation of heR ***,a series of transition metal-doped MoS_(2)materials with different surface engineered structures(Fe,Cr,V doping and S vacancies)(M-MoS_(2)/CC,M=Fe,Cr and V)were fabricated by a simple hydrothermalvulcanization strategy using Keplerate polyoxomolybdate nanoball({Mo_(72)Fe_(30)},{Mo_(72)Cr_(30)},{Mo_(72)V_(30)},{Mo_(132)})as *** enlarged interlayer spacing as well as the integration of homogeneous transition metal doping and abundant sulfur vacancies endows prepared M-MoS_(2)/CC with superior heR electrocatalytic performance and excellent long-term working stability in both acidic and alkaline *** optimized Fe-MoS_(2)/CC afford current densities of 10 and 50 mA/cm^(2)at overpotentials of 188/272 mV and 194/394 mV in 0.5 mol/L H_(2)SO_(4)and 1.0 mol/L KOH aqueous solution,respectively,outperforming most of reported typical transition metal sulfide-based *** work represents an important breakthrough for POMs-mediated highly efficient transition metal sulfide-based heR electrocatalysts with wide range pH activity and may provide new options for the rational design of promising heR electrocatalysts and beyond.

关键词： Polyoxometalate Electrocatalytic Hydrogen evolution reaction Doping MoS_(2)

Analysis of Hospital Budget Management Control Based on Smart Hospital

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Journal of Clinical and Nursing Research 2024年第5期8卷 169-173页

作者： yuqi Chen Changzhou Wujin People’s Hospital Changzhou Eighth People’s HospitalChangzhou 213000China

Hospitals are crucial healthcare facilities where patients seek treatment,and effective budget management within hospitals significantly impacts their operational efficiency and financial *** the age of information technology and advanced healthcare solutions,the emergence of smart hospitals represents a new trend in the medical industry’s *** modern information technology can enhance the development of hospital IT systems and drive budget management toward greater *** paper begins by analyzing the influence of smart hospitals on hospital budget *** then examines the current state of budget management control within smart ***,it proposes several strategies for budget management control in smart hospitals,aiming to provide guidance for relevant stakeholders.

关键词： Smart hospital Hospital management Budget management Financial control Control strategies

古代江南私家藏书传统对现代乡村文化建设的启示

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图书馆 2022年第4期 1-6页

作者：徐雁张思瑶何雨琪南京大学信息管理学院南京210023 南京大学信息管理学院图书馆学与数字人文系南京210023

文章通过梳理江南部分地区地方史志中的记载,回溯了我国古代江南私家藏书的起源和家庭读书的传统,及其与近代乡村图书馆的关系,阐述了乡村图书馆继承发扬江南文化的可能路径,如继承和发扬古代私家藏书、读书的文化传统,在老村落改造中... 详细信息

文章通过梳理江南部分地区地方史志中的记载,回溯了我国古代江南私家藏书的起源和家庭读书的传统,及其与近代乡村图书馆的关系,阐述了乡村图书馆继承发扬江南文化的可能路径,如继承和发扬古代私家藏书、读书的文化传统,在老村落改造中重视对中国传统书香遗存的保护与复原,以及建立现代公共图书馆服务到乡进村的制度等。

关键词：私家藏书乡村图书馆江南文化地方史志乡村文化建设

Gas-phase synthesis of Ti_(2)CCl_(2) enables an efficient catalyst for lithiumsulfur batteries

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The Innovation 2024年第1期5卷 33-40页

作者： Maoqiao Xiang Zihan Shen Jie Zheng Miao Song Qiya he Yafeng Yang Jiuyi Zhu yuqi Geng Fen Yue Qinghua Dong Yu Ge Rui Wang Jiake Wei Weiliang Wang Haiming Huang Huigang Zhang Qingshan Zhu Chuanfang John Zhang State Key Laboratory of Multiphase Complex Systems Institute of Process EngineeringChinese Academy of SciencesBeijing 100190China School of Chemical Engineering University of the Chinese Academy of SciencesBeijing 100049China Innovation Academy for Green Manufacture Chinese Academy of SciencesBeijing 100190China China Nuclear Power Engineering Co. Ltd.117 West Third Ring RoadNorth SectionBeijing 100840China College of Materials Science&Engineering Sichuan UniversityChengdu 610065China State Key Laboratory of Catalysis Dalian Institute of Chemical PhysicsChinese Academy of SciencesDalian 116023China School of Physics Guangdong Province Key Laboratory of Display Material and TechnologyCenter for Neutron Science and TechnologySun Yat-sen UniversityGuangzhou 510275China Solid State Physics&Material Research Laboratory School of Physics and Materials ScienceGuangzhou UniversityGuangzhou 510006China

MXenes have aroused intensive enthusiasm because of their exotic properties and promising ***,to date,they are usually synthesized by etching *** synthetic technologies provides more opportunities for innovation and may extend unexplored ***,we report a bottom-up gas-phase synthesis of Cl-terminated MXene(Ti_(2)CCl_(2)).The gas-phase synthesis endows Ti_(2)CCl_(2) with unique surface chemistry,high phase purity,and excellent metallic conductivity,which can be used to accelerate polysulfide conversion kinetics and dramatically prolong the cyclability of Li-S ***-depth mechanistic analysis deciphers the origin of the formation of Ti_(2)CCl_(2) and offers a paradigm for tuning MXene chemical vapor *** brief,the gas-phase synthesis transforms the synthesis of MXenes and unlocks the hardly achieved potentials of MXenes.

关键词： synthesis phase lithium

Unified Control Theory from PID to ACPID

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Advances in Pure Mathematics 2024年第7期14卷 523-545页

作者： Zhezhao Zeng yuqi Tang School of Electrical and Information Engineering Changsha University of Science and Technology Changsha China Hunan Zhe-Zhao Automation Control Technology Co. Ltd. Xiangtan China

To address the challenge of achieving unified control across diverse nonlinear systems, a comprehensive control theory spanning from PID (Proportional-Integral-Derivative) to ACPID (Auto-Coupling PID) has been proposed. The primary concept is to unify all intricate factors, including internal dynamics and external bounded disturbance, into a single total disturbance. This enables the mapping of various nonlinear systems onto a linear disturbance system. Based on the theory of PID control and the characteristic equation of a critically damping system, Zeng’s stabilization rules (ZSR) and an ACPID control force based on a single speed factor have been designed. ACPID control theory is both simple and practical, with significant scientific significance and application value in the field of control engineering.

关键词： Insert Nonlinear Systems PID Control ACPID Control Total Disturbance Unified Control Theory Zeng’s Stabilization Rules (ZSR)