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Hollow TiO2-x porous microspheres composed of wellcrystalline nanocrystals for high-performance lithiumion batteries

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Nano Research 2016年第1期9卷 165-173页

作者： Chun Wang Faxing Wang Yujuan Zhao Yuhui Li Qin Yue Yupu Liu Yong Liu Ahmed A. Elzatahry Abdullah Al-Enizi yuping wu Yonghui Deng Dongyuan Zhao Department of Chemistry Laboratory of Advanced Materials Shanghai Key Lab of Molecular Catalysis and Innovative Materials iChEM and State Key Laboratory of Molecular Engineering of Polymers Fudan University Shanghai 200433 China Materials Science and Technology Program College of Arts and Sciences Qatar University P.O. Box 2713 Doha Qatar Department of Chemistry College of Science King Saud University Riyadh 11451 SaudiArabia

Hollow TiO2-x porous microspheres consisted of numerous well-crystalline nanocrystals with superior structural integrity and robust hollow interior were synthesized by a facile sol-gel template-assisted approach and two-step carbonprotected calcination method, together with hydrogenation treatment. They exhibit a uniform diameter of -470 nm with a thin porous wall shell of -50 nm in thickness. The Brunauer-Emmett-Teller （BET） surface area and pore volume are -19 m2/g and 0.07 crnB/g, respectively. These hollow TiOR_x porous microspheres demonstrated excellent lithium storage performance with stable capacity retention for over 300 cycles （a high capacity of 151 mAh/g can be obtained up to 300 cycles at I C, retaining 81.6% of the initial capacity of 185 mAh/g） and enhanced rate capability even up to 10 C （222, 192, 121, and 92.1 mAh/g at current rates of 0.5, 1, 5, and 10 C, respectively）. The intrinsic increased conductivity of the hydrogenated TiO2 microspheres and their robust hollow structure benefidal for lithium ion-electron diffusion and mitigating the structural strain synergistically contribute to the remarkable improvements in their cycling stability and rate performance.

关键词： titania hydrogenation porous wallhollow microspheres lithium-ion battery

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Combining niche modeling and past demographic change for a better understanding of the population history of extant species

Combining niche modeling and past demographic change for a b...

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2018中国遗传学会第十次全国会员代表大会暨学术讨论会

作者： Wenzhi Lin Chen Zeng yuping wu Guangdong Provincial Key Laboratory of Marine Resources and Coastal Engineering Zhuhai Key Laboratory of Marine Bioresource and EnvironmentSchool of Marine SciencesSun Yat-Sen University

Background:The coalescent-based methods（such as MSVAR, PSMG and etc.） has been increasingly used to infer the past demographic trajectory of extant species. Although it has been repeatedly pointed out that the violation of models’ assumptions will lead to bias or even false detection of demographic signal, it was not uncommon to find their application performed without proper evaluation. In this study, we inferred the demographic trajectory of four geographic populations of genus Neophocaena covering a wide latitudinal range using coalescent-based techniques;meanwhile, we modeled the historic niche for this genus along China’s coastline;finally, we cross-matched the demographic history of genus and the evolutionary process of their habitat, to evaluate whether the inference under different scenarios（e.g. the mutation model of STR） will be explained by the result of niche modeling. Results: We found contrasting conclusions when different mutation models of STR were applied. Recent bottleneck was detected, though with varying estimates of the population parameters, under most of the scenarios;while expansion was detected only under GSM with a large proportion of multi-steps mutation. Niche modeling proposed that the genus re-colonize the shelf region after the end of last glacial maximum, especially in the continental sea and gulf region, which could be taken as a basis for post-glacial expansion for the genus. Moreover, evidence was detected for the presence of historic gene flow. Though we could not applied a more complex population model to rigorously quantify this parameter with the current data set, we highlight the importance of sampling scheme in inferring past demographic history using coalescent-based methods. Conclusions:Using a case of a coastal marine mammal, we show that the convergence of coalescent simulation is not necessary to be translated into a sign of proper inference of population parameters. Therefore the possible violations of model assumptions

关键词： Bottleneck finless porpoise Neophocaena genetic diversity microsatellite coalescent-based simulation niche modeling

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Thylakoid engineered M2 macrophage for sonodynamic effect promoted cell therapy of early atherosclerosis

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Nano Research 2024年第4期17卷 2919-2928页

作者： Guanghao wu Changwen Mu Qianru Zhao Yao Lei Ran Cheng Weidong Nie Jiamin Qu yuping Dong Ruili Yang Haiyan Xie State Key Laboratory of Natural and Biomimetic Drugs School of Pharmaceutical SciencesChemical Biology CenterPeking UniversityBeijing 100191China School of Materials Science and Engineering Beijing Institute of TechnologyBeijing 100081China School of Life Science Beijing Institute of TechnologyBeijing 100081China School of Stomatology Peking UniversityBeijing 100081China

Atherosclerosis is the most common cause of cardiovascular diseases that contribute to the major morbidity worldwide,but still lacking of effective treatment ***,a hybrid cell is constructed for the sonodynamic effect promoted cell therapy of early atherosclerosis by fusing M2 macrophages with thylakoid(TK)*** systemic administration,the obtained TK-M2 actively accumulates in the early atherosclerotic plaques,wherein M2 macrophages relieve the cholesterol accumulation and the inflammation in the foam ***,the TK membranes decorated on the M2 macrophages exhibit both type I and type II sonodynamic effects under ultrasound(US)activation,inducing the direct apoptosis of foam *** cooperation of M2 and TK leads to significant outcome in eliminating atherosclerotic plaques without obvious side-effects,providing a new avenue for atherosclerosis treatment.

关键词： atherosclerosis thylakoid ultrasound M2 macrophage

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不同有机肥配施对雪茄烟生长与产质量的影响

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贵州农业科学 2024年第6期52卷 47-53页

作者：吴豪孔光辉张光海赵高坤吴玉萍李薇李永平姚恒白羽祥李青云南农业大学烟草学院云南昆明650201 云南省烟草农业科学研究院云南昆明650031 云南省烟草公司普洱市公司宁洱县分公司云南宁洱665199

【目的】探明不同有机肥配施对雪茄烟生长和产质量的影响,为合理施用有机肥和制定优质雪茄烟的化学成分行业标准提供参考。【方法】以雪茄烟品种云雪39为试验材料,研究常规施肥(CK)、常规施肥+豆粕200 g/株(A1)、常规施肥+棉籽粕200 g/... 详细信息

【目的】探明不同有机肥配施对雪茄烟生长和产质量的影响,为合理施用有机肥和制定优质雪茄烟的化学成分行业标准提供参考。【方法】以雪茄烟品种云雪39为试验材料,研究常规施肥(CK)、常规施肥+豆粕200 g/株(A1)、常规施肥+棉籽粕200 g/株(A2)和常规施肥+芝麻饼200 g/株(A3)对雪茄烟农艺性状、叶片厚度、鲜叶产量和常规化学成分协调性的影响。【结果】不同有机肥处理对雪茄烟生长发育的影响存在差异。株高为86.67~136.22 cm,常规施肥+豆粕200 g/株处理较CK显著降低26.06%,常规施肥+棉籽粕200 g/株和常规施肥+芝麻饼200 g/株处理较CK显著提高16.21%和9.01%;茎围为6.83~7.42 cm,常规施肥+豆粕200 g/株处理较CK显著降低5.66%,其余处理间差异不显著;叶长为47.19~53.49 cm,常规施肥+豆粕200 g/株和常规施肥+棉籽粕200 g/株处理分别较CK显著降低11.78%和6.15%,常规施肥+芝麻饼200 g/株处理与CK无显著差异;各处理的叶宽和有效叶片数差异均不显著。不同处理烟株上部叶的叶片厚度差异均不显著;常规施肥+芝麻饼200 g/株处理烟株的中部叶和下部叶厚度分别较CK显著降低9.0%和8.7%,其余处理间显著不差异,且中部叶和下部叶的叶片厚度均为常规施肥+豆粕200 g/株>CK>常规施肥+棉籽粕200 g/株>常规施肥+芝麻饼200 g/株。鲜叶产量为1120.28~13572.10 kg/hm^(2),依次为常规施肥+棉籽粕200 g/株>常规施肥+芝麻饼200 g/株>CK>常规施肥+豆粕200 g/株。雪茄烟的农艺性状和烟叶常规化学成分协调性综合得分为常规施肥+芝麻饼200 g/株(2.80分,82.48分)>常规施肥+棉籽粕200 g/株(1.23分,81.63分)>CK(-0.75分,81.11分)>常规施肥+豆粕200 g/株(-2.42分,77.74分)。【结论】常规施肥+芝麻饼200 g/株和常规施肥+棉籽粕200 g/株有利于促进雪茄烟的生长发育,提高鲜叶产量,改善烟叶常规化学成分协调性,可在烤烟生产中推广应用。

关键词：雪茄有机肥豆粕棉籽粕芝麻饼生长发育产质量

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施肥方式对水稻产量品质和病虫害发生情况的影响

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宁波大学学报（理工版） 2024年第4期37卷 69-73页

作者：陈丁铭周瑛华孙辉钟莺莺李雅颖曹建君吴愉萍宁波市农业农村绿色发展中心浙江宁波315012 宁波市江北区农业技术推广服务站浙江宁波315000 宁波海关技术中心浙江宁波315048 中国科学院城市环境研究所浙江宁波315000 宁波市江北区兴谷水稻专业合作社浙江宁波315000

为筛选合适的施肥方案,以甬优1540品种为例,分析在绿色食品标准之下,不同的施肥方案对水稻产量、品质以及病虫害发生的影响.结果表明,未经过施肥处理的稻田产量最低,在每亩施用纯N7.5kg、P_(2)O_(5)2.8kg、K_(2)O8.0kg的基础上加施20kg... 详细信息

为筛选合适的施肥方案,以甬优1540品种为例,分析在绿色食品标准之下,不同的施肥方案对水稻产量、品质以及病虫害发生的影响.结果表明,未经过施肥处理的稻田产量最低,在每亩施用纯N7.5kg、P_(2)O_(5)2.8kg、K_(2)O8.0kg的基础上加施20kg海藻肥处理的水稻产量最高,且品质好、病虫害发生少,可作为江浙地区绿色食品水稻生产的推荐用肥.

关键词：绿色食品水稻质量水稻病虫害最佳施用方案

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Parallel Hybrid Evolutionary Algorithm based on Chaos-GA-PSO for SPICE Model Parameter Extraction

Parallel Hybrid Evolutionary Algorithm based on Chaos-GA-PSO...

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2009 IEEE International Conference on Intelligent Computing and Intelligent Systems(ICIS2009)

作者： yuping wu Institute of Microelectronics of CAS Beijing China

SPICE model is one of the key technical connections between the integrated-circuit technology community and the design *** community requires accurate SPICE model parameters so as to make the difference between design spec and practical spec minimized as *** get accurate model parameters,optimization algorithms are used for parameter extraction.A parallel hybrid evolutionary algorithm based chaos-GA-PSO is presented for SPICE model parameter extraction,which gets leverage of the advantages from chaos algorithm,genetic algorithm,and particle swarm optimization,overcomes their respective disadvantages,passes good individuals among them,avoids local area optimization efficiently,and gets more accurate global optimized parameter extraction *** such algorithm based SPICE model parameter extraction architecture is presented with model convergence checking and derivate ability checking supported.

关键词： SPICE model parameter extraction parallel global optimization generic alorithm(GA),particle swarm optimization(PSO) Message Passing Interface(MPI)

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Investigation of Oil Content in Lacustrine Shale-Oil Systems:Insights from Two Different Pyrolysis

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Journal of Earth Science 2023年

作者： yuping wu Chenglin Liu Fujie Jiang Tao Hu Chenxi Zhang Jiahao Lü Renda Huang Meiling Hu Guanyun wu Rizwan Sarwar Awan School of Resources and Environmental Engineering Hefei University of Technology Xi'an Shiyou University State Key Laboratory of Petroleum Resources and Prospecting China University of Petroleum College of Geosciences China University of Petroleum

This research has investigated the oil content of lacustrine shale-oil systems from the Junggar Basin. Twenty-eight samples are used for different pyrolysis experiments to study the characteristics of shale oil occurrence and the difference between various evaluation methods. Additionally,the factors affecting the physical states of shale oil are discussed. Compared with the standard RockEval, the two-step pyrolysis and multi-step pyrolysis can eliminate the influence of the carryover ***, these two types of pyrolysis are used to obtain the total, free, and adsorbed oil yield of the shale. The results demonstrate that the total oil yield acquired by multi-step pyrolysis is quite similar to that obtained by two-step pyrolysis. Both of them can prevent the retained oil yield from being underestimated by more than 50%. However, the free oil yield obtained by multi-step pyrolysis is significantly higher than that obtained by two-step pyrolysis. The multi-step pyrolysis can easily exaggerate the real free oil yield in resource evaluation. Therefore, this article suggests using the two-step pyrolysis to evaluate the characteristics of petroleum in shales. Furthermore, the amount of hydrocarbons within shales is related to organic matter properties. The higher the organic matter richness, the higher the total/adsorbed oil yield within the shale before reaching the adsorption saturation. The better the kerogen type, the higher the amount of liquid hydrocarbons within shales. As the thermal evolution of shales increases, the free oil proportion and the mobility of petroleum increase. This study compared different pyrolysis methods, which provided new insight for obtaining the oil content of shales, a key parameter of shale oil resource evaluation.

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灵长类动物心脏衰老中的单细胞转录组生物信息学研究

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生物化工 2024年第3期10卷 28-34页

作者：黄渊清李志雄张海涛雷宇清吴俣萍徐两蒲黄海龙福建省妇幼保健院国家卫健委非人灵长类生育调节技术评价重点实验室福建福州350005 福建省妇幼保健院/福建医科大学妇儿临床医学院医学遗传诊疗中心/福建省产前诊断与出生缺陷重点实验室福建福州350005

目的:利用单细胞转录组数据探究灵长类动物心脏衰老的潜在分子机制。方法:利用高通量测序数据库Genome Sequence Archive中查找到的和“primate cardiac aging”有关的单细胞测序原始数据集CRA002689和CRA002810,通过细胞聚类、注释和... 详细信息

目的:利用单细胞转录组数据探究灵长类动物心脏衰老的潜在分子机制。方法:利用高通量测序数据库Genome Sequence Archive中查找到的和“primate cardiac aging”有关的单细胞测序原始数据集CRA002689和CRA002810,通过细胞聚类、注释和差异表达基因分析筛选调控心脏衰老可能的信号通路。结果:过滤得到220915个细胞测序数据,其中年轻组心脏细胞78546个,年老组心脏细胞142369个,聚类成15个细胞亚群,纤维原细胞(Fib)细胞亚群占比最高。上皮细胞(Epi)中差异表达基因数目最多,而抗炎巨噬细胞(M2)中差异表达基因数目最少。差异表达基因显著富集于“supramolecular fiber organization”和“actin filament-based process”等通路。结论:上皮细胞在心脏衰老过程中发生了较大的变化,其可能在心脏衰老过程中起着重要的作用,上皮细胞的“supramolecular fiber organization”和纤维原细胞“actin filament-based process”通路与衰老密切相关。

关键词：心脏衰老单细胞转录组生物信息学

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Ginsenoside Rb3 prevents myocardial injury in sleep-deprived mice by suppressing ferroptosis through SIRT3/P53/SCL7A11/GPX4 axis

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Food Science and Human Wellness 2024年

作者： Yi wu yuping Miao Xuanxuan Huang Yin Cao Zhengtao Wang Xiaojun wu Key Laboratory of Xin'an Medicine， Ministry of Education， Anhui Province Key Laboratory of R&D of Chinese Medicine， Anhui University of Chinese Medicine Shanghai Key Laboratory of Compound Chinese Medicines， Institute of Chinese Materia Medica， Shanghai University of Traditional Chinese Medicine

Ginsenoside Rb3 (GRb3) is an active ingredient extracted from Panax ginseng， which is known to enhance blood supply to heart and treat a variety of cardiac diseases. The aim of this study was to investigate the effect of GRb3 on myocardial injury induced by sleep deprivation and its mechanisms. GRb3 20 mg/kg group showed lower heart rate (438.2 ± 10.06 bpm)， Creatine kinase (27.43 ± 2.85 U / mg prot) and Lactate dehydrogenase (412.9 ± 35.65 U / L) than SD group (592.0 ± 7.78 bpm， 44.18 ± 1.24 U / mg prot， 526.6 ± 38.18 U / L). GRb3 improved myocardial tissue damage and abnormal mitochondrial morphological changes. GRb3 also reduced the abnormal proteins expression of Atrial Natriuretic Peptide (ANP)， Sirtuin3 (SIRT3)， Tumor Protein P53 (P53)， Solute Carrier Family 7 (SLC7A11)， Glutathione peroxidase 4 (GPX4)， Transferrin Receptor Protein 1 (TFRC)， Acyl-CoA synthetase long chain family member 4 (ACSL4)， Heme Oxygenase-1 (HO-1)， Ferritin heavy polypeptide 1 (FTH1)， Ferroptosis suppressor protein 1 (FSP1). GRb3 ameliorated oxidative stress， such as Malondialdehyde (MDA，)， Glutathione (GSH)， and Superoxide dismutase (SOD). GRb3 also decreased Reactive Oxygen Species (ROS) content， restored cellular abnormal mitochondrial morphology and reversed the expression of ferroptosis-related proteins on H9c2 cells pretreated with Erastin. While the above effect could be reversed by 3-TYP. In summary， GRb3 exerts cardioprotective effects by regulating SIRT3/P53/SCL7A11/GPX4 axis to inhibit myocardial ferroptosis in sleep deprived mice. The findings imply that GRb3 holds promising potential for innovative approaches to safeguarding human cardiac health.

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Anti-tumor and anti-virus activity of polysaccharides extracted from Sipunculus nudus(SNP) on Hepg2.2.15

Anti-tumor and anti-virus activity of polysaccharides extrac...

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福建省海洋学会2016年学术年会

作者： Jie Su Linlin Jiang Jingna wu Zhiyu Liu yuping wu South China Sea Bio-Resource Exploitation and Utilization Collaborative Innovation Center School of Life SciencesGuangdong Provincial Key Laboratory of Marine Resources and Coastal EngineeringZhuhai Key Laboratory of Marine Bioresources and EnvironmentSchool of Marine SciencesSun Yat-Sen University Key Laboratory of Cultivation and High-value Utilization of Marine Organisms in Fujian Province Fujian Collaborative Innovation Center for Exploitation and Utilization of Marine Biological ResourcesFisheries Research Institute of Fujian

Many polysaccharides have biological activities and have been investigated for their antitumor *** this study,we investigated the anti-tumor activity and anti-virus activity of SNP—the water-soluble polysaccharides extracted from Sipunculus nudus on *** cytometry analysis demonstrated that SNP induced dose-dependent cell apoptosis on ***-time PCR and Western Blot analysis showed that SNP down-regulated the synthesis of HBsAg,HBV-DNA and enhanced the expression of pro-apoptosis proteins TNF-ci,caspase-3,and Bax,while decreasing the expression of the antiapoptosis proteins *** *** results suggested that SNP suppressed cell viability of Hepg2.2.15 and that could be a novel anti-tumor and anti-HBV agent.

关键词： Polysaccharide Sipunculus nudus Anti-tumor activity Anti-virus activity

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