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火灾高温下混凝土柱温度场的解析解

应用力学学报 2018年第6期35卷 1361-1365,1427页

作者：唐松花崔宇鹏中南大学土木工程学院长沙410075

应用杜哈美尔定理推导得到了火灾高温下混凝土柱二维温度场的解析解计算表达式。因为混凝土的热扩散系数随温度变化,在温度场计算中采用了时间差分法。应用Matlab编程计算得到了柱温度场的解析解结果。得到:计算结果与实验结果在靠近边... 详细信息

应用杜哈美尔定理推导得到了火灾高温下混凝土柱二维温度场的解析解计算表达式。因为混凝土的热扩散系数随温度变化,在温度场计算中采用了时间差分法。应用Matlab编程计算得到了柱温度场的解析解结果。得到:计算结果与实验结果在靠近边界处基本吻合,误差只有2.5%,且边界处正是最先发生破坏的位置;截面温度变化趋势基本一致,从边界到中心区域温度逐渐降低。说明该解析解计算公式可以用来确定火灾高温下混凝土柱的截面温度场分布。

关键词：杜哈美尔定理二维温度场解析解时间差分法

Comparative Analysis of Salinity-Induced Proteomic Changes in Cotton (Gossypium hirsutum L.)

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Agricultural Sciences 2015年第1期6卷 78-86页

作者： yupeng cui Xuke Lu Delong Wang Junjuan Wang Zujun Yin Weili Fan Shuai Wang Wuwei Ye State Key Laboratory of Cotton Biology Institute of Cotton Research of Chinese Academy of Agricultural Sciences Anyang China

Salt stress on cotton varieties of distinct salinity tolerance can induce expression of different proteins. Zhong 07, a salt-tolerant variety and Zhong s9612, a salt-sensitive variety, were utilized as experimental materials. The leaves of trefoil seedlings treated with or without 0.4% NaCl for 24 h were harvested for whole-protein extraction. Two-dimensional technology, combined with mass spectroscopy (MS) analysis and protein database searching, was employed to detect differentially expressed proteins and determine their identities and biological functions. Compared with the control, Zhong 07 showed 10 differentially expressed proteins under salt stress, of which 6 were upregulated and 4 were downregulated. Meanwhile, 12 differentially expressed proteins were detected in Zhong s9612 under salt stress, of which 10 were upregulated and 2 were downregulated. In the matrix-assisted laser desorption-ionization/time of flight-time of flight/MS analysis, 14 differentially expressed proteins were successfully identified, including the ribulose-1, 5-bisphosphate carboxylase/oxygenase (RuBisco) large subunit-binding protein subunit alpha (RuBisco α), luminal binding protein (LBP), heat shock protein 70 (Hsp1, 2, 3), pathogenesis-related protein class 10 (PR-10), quinoneoxidoreductase-like protein (QOR), S-adenosylmethioninesyn-thetase (SAMS), enolase (EN), and RuBisco large subunit-binding protein subunit beta (RuBisco β). Cellular function is ultimately executed by proteins, and cotton varieties with different salt tolerance can be influenced by salt stress to various degrees, which can provide certain theoretical foundation for the identification of salt tolerance of cotton varieties. The findings also provide some proteins, such as the RuBisco large subunit binding proteins α and β subunits, OEE2 protein, HSP70, and S-adenosylmethionine synthetase, which can be used as protein markers of salt-to-lerance before- and post-treatment, making a big difference in salt-toleranc

关键词： Upland Cotton (Gossypium hirsutum L.) Salt Stress Differential Protein Mass Spectrum Analysis

大跨度无支撑甲板拓扑-尺寸-材料联合优化设计

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中国机械工程 2022年第23期33卷 2879-2887,2897页

作者：崔宇朋余杨余建星李振眠天津大学水利工程仿真与安全国家重点实验室天津300072 天津大学天津市港口与海洋工程重点实验室天津300072

提出了一种加筋板概念-详细联合设计框架,以开展空间约束下的大跨度无支撑甲板刚度、变形及动态振动性能拓扑-尺寸-材料综合优化研究。应用加筋板拓扑设计域降维处理策略解决了大跨度甲板三维实体单元断连及计算效率低的问题。提出了兼... 详细信息

提出了一种加筋板概念-详细联合设计框架,以开展空间约束下的大跨度无支撑甲板刚度、变形及动态振动性能拓扑-尺寸-材料综合优化研究。应用加筋板拓扑设计域降维处理策略解决了大跨度甲板三维实体单元断连及计算效率低的问题。提出了兼顾迭代效率和逼近全局最优解的三段式延拓(TSC)法并应用于大跨度甲板的应变能、多工况位移及一阶动态频率的概念设计。通过480个加筋板刚度最大化算例证明了TSC法的有效性。提出了尺寸/材料一体化设计方法,并联合自动化技术对大跨度甲板概念结构进行了详细设计以便工程化制造,即曲形T形梁的截面尺寸、面板厚度及材料弹性模量组合优化。结果表明:与传统大跨度甲板相比,通过加筋板概念-详细联合设计框架高效获得的曲形大跨度无支撑甲板具备空间及性能(刚度、变形、动态振动)的双重优势。

关键词：拓扑-尺寸-材料联合优化降维处理策略三段式延拓法大跨度无支撑甲板

High-speed GeSn resonance cavity enhanced photodetectors for a 50 Gbps Si-based 2 μm band communication system

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Photonics Research 2024年第4期12卷 767-773页

作者： JINLAI cui JUN ZHENG yupeng ZHU XIANGQUAN LIU YIYANG WU QINXING HUANG YAZHOU YANG ZHIPENG LIU ZHI LIU YUHUA ZUO BUWEN CHENG Key Laboratory of Optoelectronic Materials and Devices Institute of SemiconductorsChinese Academy of SciencesBeijing 100083China Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijing 100049China

Expanding the optical communication band is one of the most effective methods of overcoming the nonlinear Shannon capacity limit of single *** this study,GeSn resonance cavity enhanced(RCE)photodetectors(PDs)with an active layer Sn component of 9%–10.8%were designed and fabricated on an SOI *** GeSn RCE PDs present a responsivity of 0.49 A/W at 2μm and a 3-dB bandwidth of approximately 40 GHz at 2μ***,Si-based 2μm band optical communication with a transmission rate of 50 Gbps was demonstrated by using a GeSn RCE *** work demonstrates the considerable potential of the Si-based 2μm band photonics in future high-speed and high-capacity optical communication.

关键词： resonance system approximate

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单轨吊在大采高工作面中的应用及改进措施

能源与节能 2019年第1期 169-171页

作者：崔宇鹏山西三元福达煤矿有限公司山西长子046600

叙述了无极绳绞车牵引运输方式的缺点,为提高煤矿井下辅助运输系统的效率,提出了可在大采高工作面中采用单轨吊辅助运输系统。分析了单轨吊及其应用中的人为故障、机械事故问题,并提出了改进措施。

关键词：无极绳连续牵引车单轨吊人为故障机械事故

改进博弈论四重组合赋权法下的开口甲板多目标拓扑优化设计

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机械工程学报 2023年第9期59卷 263-273页

作者：崔宇朋余杨韦明秀李振眠余建星天津大学水利工程仿真与安全国家重点实验室天津300072 天津大学天津市港口与海洋工程重点实验室天津300072

结构刚度、振动及开口处强度影响开口甲板服役寿命。针对开口甲板型式,以多项式惩罚模型(Polynomial penalization model,PPM)为理论依据并辅以三段式延拓(Three-stage continuation,TSC)法,提出一种基于折衷规划法(Compromise programm... 详细信息

结构刚度、振动及开口处强度影响开口甲板服役寿命。针对开口甲板型式,以多项式惩罚模型(Polynomial penalization model,PPM)为理论依据并辅以三段式延拓(Three-stage continuation,TSC)法,提出一种基于折衷规划法(Compromise programming method,CPM)和改进博弈论四重组合赋权法(Improved fourfold combination weighting model of game theory,IFCWGT)的强度-刚度-振动多目标拓扑优化(Topology optimization,TO)综合策略。为缓解传统变密度法收敛至局部最优解及局部模态问题,将应用TSC技术的PPM引入至开口甲板多目标概念设计领域。建立结合CPM和PPM-TSC的最大单元应力最小化、静态多应变能最小化、动态多频率最大化的多目标TO模型并应用β法以获取Pareto妥协解。提出利用博弈论思想无偏好耦合层次分析(Analytic hierarchy process,AHP)法、熵权法(Entropy weight method,EWM)、基于层间相关性(Criteria importance through intercriteria correlation,CRITIC)法及变异系数法(Coefficient of variation method,CVM)的IFCWGT策略,以得到兼具设计决策者主观价值和数据客观性的子目标综合权重因子。研究表明,所提出的融合四种主客观赋权法的IFCWGT技术在子目标权重分配及开口甲板拓扑性能、拓扑布局方面更具先进性。

关键词：开口甲板多目标拓扑优化折衷规划法改进博弈论四重组合赋权法多项式惩罚模型 β法三段式延拓法

A genomic association study revealing subphenotypes of childhood steroid-sensitive nephrotic syndrome in a larger genomic sequencing cohort

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Genes & Diseases 2024年第4期11卷 400-410页

作者： Han Chan Fenfen Ni Bo Zhao Huimin Jiang Juanjuan Ding Li Wang Xiaowen Wang Jingjing cui Shipin Feng Xiaojie Gao Xueying Yang Huan Chi Hao Lee Xuelan Chen Xiaoqin Li Jia Jiao Daoqi Wu Gaofu Zhang Mo Wang yupeng Cun Xiongzhong Ruan Haiping Yang Qiu Li Department of Nephrology Children's Hospital of Chongqing Medical UniversityNational Clinical Research Center for Child Health and DisordersMinistry of Education Key Laboratory of Child Development and DisordersChongqing Key Laboratory of PediatricsChongqing 400014China Department of Nephrology Shenzhen Children's HospitalShenzhenGuangdong 518034China Department of Nephrology Kunming Children's HospitalKunming Medical UniversityKunmingYunnan 650228China Department of Nephrology Wuhan Children's HospitalTongji Medical College of Huazhong University of Science and TechnologyWuhanHubei 430015China Department of Nephrology Chengdu Women and Children Central HospitalChengduSichuan 610073China Pediatric Research Institute Ministry of Education Key Laboratory of Child Development and DisordersNational Clinical Research Center for Child Health and DisordersChina International Science and Technology Cooperation Base of Child Development and Critical DisordersChongqing Key Laboratory of Translational Medical Research in Cognitive Development and Learning and Memory DisordersChildren's Hospital of Chongqing Medical UniversityChongqing 400014China Department of Nephrology John Moorhead Research LaboratoryUniversity College London Medical SchoolRoyal Free CampusUniversity College LondonLondon NW32PFUnited Kingdom

Dissecting the genetic components that contribute to the two main subphenotypes of steroid-sensitive nephrotic syndrome(SSNS)using genome-wide association studies(GWAS)strategy is important for understanding the *** conducted a multicenter cohort study(360 patients and 1835 controls)combined with a GWAS strategy to identify susceptibility var-iants associated with the following two subphenotypes of ssNS:steroid-sensitive nephrotic syn-drome without relapse(SSNswR,181 patients)and steroid-dependent/frequent relapse nephrotic syndrome(SDNS/FRNS,179 patients).The distribution of two single-nucleotide poly-morphisms(SNPs)in ANKRD36 and ALPG was significant between SSNSWR and healthy controls,and that of two SNPs in GAD1 and HLA-DQA1 was significant between SDNS/FRNS and healthy ***,rs1047989 in HLA-DQA1 was a candidate locus for SDNS/FRNS but not for *** significant SNPs were observed between SSNSWR and SDNS/***,chromosome 2:171713702 in GAD1 was associated with a greater steroid dose(>0.75 mg/kg/d)upon relapse to first remission in patients with SDNS/FRNS(odds ratio=3.14;95%confidence interval,0.97-9.87;P=0.034).rs117014418 in APOL4 was significantly associated with a decrease in eGFR of greater than 20%compared with the baseline in SDNS/FRNS patients(P=0.0001).Protein-protein intersection network construction suggested that HLA-DQA1 and HLA-DQB1 function together through ***,SSNSWR belongs to non-HLA region-dependent nephropathy,and the HLA-DQA/DQB region is likely strongly associated with dis-ease relapse,especially in SDNS/*** study provides a novel approach for the GWAS strategy of SsNS and contributes to our understanding of the pathological mechanisms of SSNSWRandSDNS/FRNS.

关键词： Frequentrelapse Genome-wide association study Human leukocyte antigen region Steroid-sensitive nephrotic syndrome

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电磁层析成像技术在刹车盘缺陷检测中的应用

中国电机工程学报 2021年第5期41卷 1894-1902页

作者：岳远里刘泽武建利苗宇刘向龙崔玉鹏北京交通大学电子信息工程学院北京市海淀区100044

针对列车刹车盘缺陷检测的实际需求,提出采用电磁层析成像技术(electromagnetic tomography,EMT)对刹车盘进行缺陷检测,检测得到的数据经过图像重建后对缺陷的位置、形状和大小等分布信息进行显示。根据列车刹车盘的结构特点,设计平板... 详细信息

针对列车刹车盘缺陷检测的实际需求,提出采用电磁层析成像技术(electromagnetic tomography,EMT)对刹车盘进行缺陷检测,检测得到的数据经过图像重建后对缺陷的位置、形状和大小等分布信息进行显示。根据列车刹车盘的结构特点,设计平板型传感器线圈阵列,通过电磁场仿真软件对不同缺陷的刹车盘模型进行仿真,并使用不同算法进行缺陷成像。通过评价指标对比了不同算法的图像重建质量,仿真结果验证了电磁层析成像技术用于列车刹车盘缺陷检测的可行性;搭建了刹车盘缺陷检测的EMT实验系统,对刹车盘缺陷进行数据采集与成像实验。实验结果表明,电磁层析成像技术在高速列车刹车盘缺陷检测中具有很好的应用前景。

关键词：电磁层析成像刹车盘缺陷检测传感器线圈阵列图像重建实验系统

老年人药物素养状况及影响因素——以山东省为例

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中国卫生事业管理 2021年第6期38卷 477-480页

作者：崔钰鹏娄鹏宇许兴龙周绿林江苏大学管理学院江苏镇江212013 潍坊医学院管理学院

目的:对山东省老年人的药物素养状况进行调查,分析影响药物素养的主要因素,方法:采用多阶段分层随机抽样,在2019年4-5月对山东省威海市、淄博市、菏泽市的12个社区1100名老年人进行问卷调查:用描述性统计分析老年人个人基本情况与药物... 详细信息

目的:对山东省老年人的药物素养状况进行调查,分析影响药物素养的主要因素,方法:采用多阶段分层随机抽样,在2019年4-5月对山东省威海市、淄博市、菏泽市的12个社区1100名老年人进行问卷调查:用描述性统计分析老年人个人基本情况与药物素养水平,使用Kruskal Wallis H检验、方差分析和多元线性线性回归分析药物素养的影响因素。结果:山东省老年人药物素养得分为(7.19±3.72)分,居住地、有无慢性病、服药数、文化程度、吃药时是否给予指导、就诊次数、婚姻状况、经济状况、职业、个人健康状况对老年人药物素养的差异有统计学意义。多元线性回归分析表明,居住地、服药数、文化程度、吃药时是否给予指导与婚姻状况是影响老年人药物素养水平的主要因素。结论:山东省老年人的药物素养处于中等水平居住地在城镇、服药数目多、文化程度高、吃药时未给予指导、家庭组成结构完整的老年人药物素养相对较高。可通过政府、医药企业、社区、家庭之间加强合作,重点人群重点突破,发挥家庭医生作用,完善基础设施建设等措施来提高老年人药物素养水平。

关键词：老年人药物素养影响因素