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Science China(Physics,Mechanics & Astronomy) 2012年第3期55卷 561-562页

作者： wu yunzhao School of Geographic and Oceanographic Sciences Nanjing UniversityNanjing 210093China

The boxes of "Badline Repair", "Bad pixel Repair" and "Destriping" shown in Figure 3 of the original paper should be in dashed line (see Figure 1) in ref. [1]. They are the ten- tative work for the following work for producing the global map of the absorption center of the mafic minerals. Relative calibration is the crucial step in the application of IIM data. In this study we have tested "Badline Repair", "Destriping" and "Flat-field Correction". By many tests we chose the "Flat-field Correction" for the relative calibration while other boxes were abandoned. The reason is as follows.

关键词：全球地图吸收中心矿物质镁铁质物理学报天文学科学中国

Inversion of the asymmetry factor for desert areas of China

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Science China Earth Sciences 2010年第4期53卷 561-567页

作者： wu yunzhao LU HuaYu LIU Qiang School of Geographic and Oceanographic Sciences Nanjing UniversityNanjing 210093China Institute of Remote Sensing Applications Chinese Academy of SciencesBeijing 100101China

Deserts,which have high surface albedo and wide area,are important components of the earth *** is very important for the research of surface radiation and energy balance to understand the anisotropic scattering of desert *** emergence and development of multi-angle remote sensing made possible the inversion of the anisotropic scattering of desert areas at the regional or global ***,this paper explored the accuracy of the inversion of asymmetry factor using the Hapke model and the simulated single-and multi-phase MISR *** on the results,the asymmetry factor of representative surface of desert areas in northwestern China was *** values of the asymmetry factor retrieved from MISR data were compared with the values retrieved from the laboratory *** results showed that the single-phase MISR data could be used for the inversion of asymmetry parameter of desert *** sign of the asymmetry parameter for the laboratory measurements was positive,which suggests that the surface of laboratory samples is forward *** sign of the asymmetry parameter for MISR data was negative;that is,it is *** values of the asymmetry parameters retrieved from MISR data were related to the character of the land *** Loulan,where the surface was smoother than other sites,retrieved values exhibited the largest negative values of asymmetry factor,suggesting the strongest *** sand dune area of the Kumtag Desert,which has the greatest roughness,had only slightly negative asymmetry factor *** findings indicated that at the sensor scale,a rough surface(e.g.,dunes) does not necessarily mean more backscattering than a smooth *** finding has significant implications for empirical methods(e.g.,using the normalized index of backward-scattered radiance minus forward-scattered radiance as an indicator of surface roughness),which should be used carefully for analyzing surface roughness from the remote

关键词： MISR Hapke model asymmetry parameter inversion Kumtag Desert multi-angle remote sensing

The improvement of cross-calibration of IIM data and band selection for FeO inversion

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Science China(Physics,Mechanics & Astronomy) 2013年第11期56卷 2216-2225页

作者： WANG Chao wu yunzhao SHI RunHe GAO Wei Key Laboratory of Geographical Information Science Ministry of EducationEast China Normal University Branch of Data Application System Center of Space ExplorationMinistry of EducationEast China Normal University School of Geographic and Oceanographic Sciences Nanjing University

Chang’E-1(CE-1)Interference Imaging Spectrometer(IIM)dataset suffers from the weak response in the near infrared(NIR)bands,which are the important wavelength for retrieving the minerals and elements of the *** this paper,the cross-calibration was implemented to the IIM hyperspectral data for improving the weak response in NIR *** results show that the cross-calibrated IIM spectra were consistent to the Earth-based telescopic spectra,which suggests that the cross-calibration yields acceptable *** further validating the influence of the cross-calibration on the FeO inversion and searching the optimal bands to retrieve lunar FeO contents,four band selection schemes were designed to retrieve FeO using the original and cross-calibrated IIM *** comparing the distribution patterns and histograms of the IIM derived FeO contents with the Clementine derived FeO,the IIM 891 nm band after cross-calibration showed a higher accuracy in the FeO inversion,hence most useful for lunar FeO inversion.

关键词： IIM cross-calibration band selection FeO Moon

Impact crater recognition methods:A review

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Science China Earth Sciences 2024年第6期67卷 1719-1742页

作者： Dong CHEN Fan HU Liqiang ZHANG yunzhao wu Jianli DU Jiju PEETHAMBARAN College of Civil Engineering Nanjing Forestry UniversityNanjing 210037China Department of Geography State Key Laboratory of Remote Sensing ScienceFaculty of Geographical ScienceBeijing Normal UniversityBeijing 100875China Purple Mountain Observatory Chinese Academy of SciencesNanjing 210023China Key Laboratory of Space Object and Debris Observation Chinese Academy of SciencesNanjing 210023China Department of Mathematics and Computing Science Saint Mary’s UniversityHalifaxNS B3H 3C3Canada

Impact craters are formed due to the high-speed collisions between small to medium-sized celestial *** is the most significant driving force in the evolution of celestial bodies,and the impact craters provide crucial insights into the formation,evolution,and impact history of celestial *** this paper,we present a detailed review of the characteristics of impact craters,impact crater remote sensing data,recognition algorithms,and applications related to impact *** first provide a detailed description of the geometric texture,illumination,and morphology characteristics observed in remote sensing data of *** we summarize the remote sensing data and cataloging databases for the four terrestrial planets(i.e.,the Moon,Mars,Mercury,and Venus),as well as the impact craters on ***,we study the advancement achieved in the traditional methods,machine learning methods,and deep learning methods applied to the classification,segmentation,and recognition of impact ***,based on the analysis results,we discuss the existing challenges in impact crater recognition and suggest some ***,we explore the implementation of impact crater detection algorithms and provide a forward-looking perspective.

关键词： Terrestrial planets Deep space exploration Impact crater Impact crater recognition Deep learning

Inversion of the Main Mineral Compositions and Subdivision of Tectonic Units on Lunar LQ-4 based on Chang'e Data

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Acta Geologica Sinica(English Edition) 2015年第6期89卷 1882-1894页

作者： WANG Xiang CHEN Jianping XU Yanbo ZHENG Yongchun YAN Bokun wu yunzhao China University of Geosciences The Institute of High and New Techniques applied to Land Resources China University of Geosciences Shandong Gold Geology and Mineral Exploration Co. Ltd. National Astronomical Observatories Chinese Academy of Sciences China Aero Geophysical Survey and Remote Sensing Center for Land and Resources School of Geographic and Oceanographic Sciences of Nanjing University

Spectra are sensitive in detecting main minerals on the lunar surface from visible light to infrared light. Since spectral characteristics of minerals are closely related to their compositions and the maturity level of soil on the Moon, studying the compositions and distribution of elements and minerals on the lunar surface can help to understand the evolution of the Moon through remote sensing technology. The correlation between the spectral characteristics of Chang＇e-1 interference imaging spectrometry（IIM） reflectance images and the mineral contents of LSCC（Lunar Soil Characterization Consortium） lunar surface mineral samples was discussed and the spatial distributions of Fe O and Al_2O_3 contained in both pyroxene and plagioclase on LQ-4 were studied using the improved angle parameter method, MNF, and band ratio statistics. A comparison of the mapping results of the optical models by Lucey, Shkuractov and other researchers on Clementine and the gamma ray spectrometry data shows that the content error is within 0.6% for lunar mare areas and close to 1% for the highland areas. The tectonic framework on the lunar surface was also investigated. And based on integrated analysis of previous findings on topography of the lunar surface, Chang＇e LAM, CCD and LOLA images and the gravity anomalies data（Clementine GLGM-2）, the tectonic unit subdivision was established for LQ-4, the idea of subdividing the lunar tectonic units was proposed, and this will provide a good foundation for studying the lunar tectonic evolution.

关键词： Lunar Chang'e-1 mineral composition MNF tectonic units tectonic elements

Absolute calibration of the Chang'E-1 IIM camera and its preliminary application

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Science China(Physics,Mechanics & Astronomy) 2009年第10期52卷 1842-1848页

作者： wu yunzhao XU XiSheng XIE ZhiDong TANG ZeSheng Collaborative Research Laboratory on Lunar and Planetary Exploration Macao University of Science and TechnologyTaipaMa-caoChina School of Geographic and Oceanographic Sciences Nanjing UniversityNanjing 210093China Department of Earth Sciences Nanjing UniversityNanjing 210093China

The interference imaging spectroradiometer (IIM) onboard the first lunar satellite of China "Chang'E-1" can now provide approximately global high spectral and spatial resolution reflectance spectra of the Moon. It is the essential instrument with which to accomplish one of the four missions of the first lunar satellite of China. As the current data provided by the Lunar Exploration Program Center and National Astronomical Observatories (NAOC) are not reflectance and the sensor response is inhomogeneous in the line direction,users can not use the current data directly. Moreover,due to the narrow band range,IIM data cannot cover the absorption peak of the mafic minerals of the Moon completely,which limits its ability for identifying minerals. The main objective of this study is to describe the methods for absolute calibration,correction and acquiring the absorption center of minerals for IIM data. The results from our study show that in the space domain the sensor response decreases toward the left,and in the spectral domain the response of the longer bands is more inhomogeneous than that of the shorter bands. After the calibration and correction,the reflectance of IIM matches the earth-based telescopic spectra well,which suggests the possible use of the processed data in the geological research. A high correlation was found between the absorption center and the wavelength at which the first derivative equals 0,i.e.,the so-called Stagnation Point in the mathematical sense. In the end,we show a preliminary applied study of the two craters with diameter larger than 35 km using the calibrated data. The spectra of IIM data show that the lunar crust has compositional diversity within the km scale. Pure anorthosite may be found on the wall and floor of the Aristarchus crater with the map of absorption center,which indicates that anorthosite is ubiquitously present within the lunar crust. IIM,with its capacity to acquire lunar composition at the regional and global scale,wil

关键词： Chang’E-1 IIM calibration radiometric Correction the Moon

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Global absorption center map of the mafic minerals on the Moon as viewed by CE-1 IIM data

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Science China(Physics,Mechanics & Astronomy) 2010年第12期53卷 2160-2171页

作者： wu yunzhao ZHANG Xia YAN BoKun GAN FuPing TANG ZeSheng XU AoAo ZHENG YongChun ZOU YongLiao School of Geographic and Oceanographic Sciences Nanjing UniversityNanjing 210093China Institute of Remote Sensing Applications Chinese Academy of SciencesBeijing 100101China Institute for Remote Sensing Method China Aero Geophysical Survey and Remote Sensing Center for Land and ResourcesBeijing 100083China Collaborative Research Laboratory on Lunar and Planetary Exploration Macao University of Science and TechnologyTaipaMacaoChina National Astronomical Observatories Chinese Academy of SciencesBeijing 100012China

Determining the global distribution of minerals on the Moon has been an important goal of lunar science. Hyperspectral remote sensing is an important approach to acquiring minerals on the Moon on the global scale. The wavelength of the absorption band center is the key parameter for identifying minerals with reflectance spectra as well as remote sensing data. The global absorption center map of the mafic minerals of the Moon was produced for the first time with the Chang’E-1 IIM data. This map shows the global distribution of mafic minerals such as orthopyroxenes, clinopyroxenes, and olivine and even plagioclase feldspar of the Moon. The validation for some representative areas indicates that the global map is reliable and even more detailed than the results derived from Clementine-data. Moreover, our method is insensitive to the topography and viewing and illumination geometries. The global absorption band center map not only contributes to the lunar science research, but also has other implications to be further studied. Moreover, the preprocessing methods such as calibration and correction introduced in this study can be useful in other research with IIM data.

关键词： Chang’E-1 IIM absorption band center calibration Moon

YL064 activates proteasomal-dependent degradation of c-Myc and synergistically enhances the anti-tumor activity of ABT-199 in diffuse large B cell lymphoma

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Signal Transduction and Targeted Therapy 2020年第1期5卷 1441-1444页

作者： Huizhuang Shan Yang Cao Xinhua Xiao Meng Liu yunzhao wu Qi Zhu Hanzhang Xu Hu Lei Zhujun Yao Yingli wu Hongqiao International Institute of Medicine Tongren Hospital/Faculty of Basic MedicineChemical Biology Division of Shanghai Universities E-InstitutesKey Laboratory of Cell Differentiation and Apoptosis of the Chinese Ministry of EducationShanghai Jiao Tong University School of MedicineShanghai 200025China Department of Hematology The Third Affiliated Hospital of Soochow UniversityChangzhouJiangsu Province 213003PR China State Key Laboratory for Medical Genomics Shanghai Institute of HematologyCollaborative Innovation Center of HematologyNational Research Center for Translational MedicineRuijin HospitalShanghai Jiao Tong University School of MedicineShanghai 200025China Institute of Oncology Shanghai 9th People’s HospitalShanghai Jiao Tong University School of Medicine639 Zhizaoju RdShanghai 200011China State Key Laboratory of Coordination Chemistry Jiangsu Key Laboratory of Advanced Organic MaterialsSchool of Chemistry and Chemical EngineeringNanjing University163 Xianlin AvenueNanjingJiangsu 210023China

Dear Editor,c-Myc is highly associated with poor prognosis and aggressive progression of diffuse large B cell lymphoma(DLBCL)and is thus a desirable drug ***,studies indicate that 5–15%of DLBCL patients harbor MYC and BCL-2 translocations,while 20–35%DLBCL patients simultaneously overexpress of c-Myc and BCL-2 proteins without gene rearrangements.1 These two types of DLBCL are referred as“double-hit”lymphoma(DHL)and“double-expressor”lymphoma(DEL),*** DHL and DEL lymphomas have inferior clinical outcomes and are refractory to R-CHOP or even hematopoietic stem cell transplant.2 Thus,targeting both c-Myc and BCL-2 is a promising strategy to treat high-risk DLBCLs.3 Although BCL-2 inhibitors are clinically available,c-Myc remains to be“undruggable”owing to its lack of kinase activity and intrinsically disordered structure.4 Thus,developing clinically applicable c-Myc inhibitor remains challenging.

关键词： lymphoma synergistic harbor

Hsp90/C terminal Hsc70-interacting protein regulates the stability of Ikaros in acute myeloid leukemia cells

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Science China(Life Sciences) 2021年第9期64卷 1481-1490页

作者： Meng Liu Jin Jin Yanjie Ji Huizhuang Shan Zhihui Zou Yang Cao Li Yang Ligen Liu Li Zhou Hu Lei yunzhao wu Hanzhang Xu Yingli wu Hongqiao International Institute of Medicine Shanghai Tongren Hospital/Faculty of Basic MedicineChemical Biology Division of Shanghai Universities E-InstitutesKey Laboratory of Cell Differentiation and Apoptosis of the Chinese Ministry of EducationShanghai Jiao Tong University School of MedicineShanghai 200025China Department of Ultrasound Second Affiliated Hospital of Zhejiang UniversityHangzhou 310009China Department of Hematology The Third Affiliated Hospital of Soochow UniversityChangzhou 213003China Shanghai Institute of Hematology State Key Laboratory of Medical GenomicsNational Research Center for Translational Medicine at ShanghaiRuijin Hospital affiliated to Shanghai Jiao Tong University School of MedicineShanghai 200025China

The stability of Ikaros family zinc finger protein 1(Ikaros),a critical hematopoietic transcription factor,can be regulated by cereblon(CRBN)ubiquitin ligase stimulated by immunomodulatory drugs in multiple ***,other stabilization mechanisms of Ikaros have yet to be *** this study,we show that the pharmacologic inhibition or knockdown of Hsp90 downregulates Ikaros in acute myeloid leukemia(AML)*** inhibitor MG132 but not autophagy inhibitor chloroquine could suppress the Hsp90 inhibitor STA-9090-induced reduction of Ikaros,which is accompanied with the increased ubiquitination of ***,Ikaros interacts with E3 ubiquitin-ligase C terminal Hsc70 binding protein(CHIP),which mediates the STA-9090-induced ubiquitination of *** addition,the knockdown of Ikaros effectively inhibits the proliferation of leukemia cells,but this phenomenon could be rescued by Ikaros ***,our findings indicate that the interplay between HSP90 and CHIP regulates the stability of Ikaros in AML cells,which provides a novel strategy for AML treatment through targeting the HSP90/Ikaros/CHIP axis.

关键词： Ikaros CHIP Hsp90 AML STA-9090

Roadmap for single-molecule surface-enhanced Raman spectroscopy

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Advanced Photonics 2020年第1期2卷 21-40页

作者： Yang Yu Ting-Hui Xiao yunzhao wu Wanjun Li Qing-Guang Zeng Li Long Zhi-Yuan Li wuyi University School of Applied Physics and MaterialsJiangmenChina University of Tokyo Department of ChemistryTokyoJapan South China University of Technology School of Physics and OptoelectronicsGuangzhouChina

In the near future,single-molecule surface-enhanced Raman spectroscopy(SERS)is expected to expand the family of popular analytical tools for single-molecule *** provide a roadmap for achieving single molecule SERS through different enhancement strategies for diverse *** introduce some characteristic features related to single-molecule SERS,such as Raman enhancement factor,intensity fluctuation,and data *** then review recent strategies for enhancing the Raman signal intensities of single molecules,including electromagnetic enhancement,chemical enhancement,and resonance enhancement *** demonstrate the utility of single-molecule SERS in practical applications,we present several examples of its use in various fields,including catalysis,imaging,and ***,we specify current challenges in the development of single-molecule SERS and propose corresponding solutions.

关键词： surface-enhanced Raman spectroscopy plasmonics single-molecule SERS