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基于新能源汽车教学交互系统在创新实践课程中的探索与实践

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时代汽车 2024年第5期 22-24页

作者：肖芳林鹏夏云彦哈尔滨理工大学黑龙江省哈尔滨市150080

本文探讨了新能源汽车教学交互系统的设计与开发,以及其与创新实践课程的融合。该系统的设计包括需求分析、系统架构设计、开发与测试、教材整合、用户培训与支持等关键步骤。系统与创新实践课程的融合主要通过虚拟实验模拟、实时互动... 详细信息

本文探讨了新能源汽车教学交互系统的设计与开发,以及其与创新实践课程的融合。该系统的设计包括需求分析、系统架构设计、开发与测试、教材整合、用户培训与支持等关键步骤。系统与创新实践课程的融合主要通过虚拟实验模拟、实时互动学习、实际案例分析和学习进度跟踪来实现。这种深度融合为学生提供了丰富的实际操作和互动学习机会,有助于他们在新能源汽车领域获得成功。评估与改进是系统与课程融合的持续过程,通过不断收集反馈并进行相应调整,系统和课程能够不断提高教育质量和学生的学习体验。

关键词：新能源汽车教学交互系统创新实践课程虚拟实验

Relationships between cardinal features of obstructive sleep apnea and blood pressure: a retrospective study

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Relationships between cardinal features of obstructive sleep...

中国睡眠研究会第十四届全国学术年会

作者： yunyan xia Hengtao Zhu Yuanping Xiong Shanghai Jiao Tong University Affiliated Sixth People’s Hospital

Purpose Obstructive sleep apnea(OSA) is associated with hypertension;however, the associations between cardinal features of OSA, such as intermittent hypoxia(IH) and sleep fragmentation(SF), and blood pressure remain unclear. We performed this study to address this *** We investigated 335 subjects with the polysomnography(PSG) tests. Data, including basic characteristics, PSG parameters, and blood pressure, were collected. We calculated p values for linear trends across oxygen-desaturation index(ODI)/microarousal index(MAI) quartiles. Logistic regressions were used to determine the risk factors for abnormal blood pressure and to detect the multiplicative *** After adjusting for multiple variables, a positive dose-response relationship between blood pressure and ODI quartiles was seen. A positive independent linear trend for risk of abnormal diastolic blood pressure(DBP) across ODI quartiles was demonstrated, and subjects in higher ODI quartiles were at a higher risk for hypertension than those in lower ODI quartiles. Similarly, a positive dose-response relationship between blood pressure and MAI quartiles, and a positive linear trend for the risk of abnormal DBP across MAI quartiles were seen. Subjects in a higher MAI quartile were at a higher risk for hypertension. No significant multiplicative interactions between ODI and MAI were *** We found positive relationships between IH/SF and elevated blood pressure. No interaction between IH and SF on the relationship with abnormal blood pressure was shown.

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Changes in cerebral metabolites in obstructive sleep apnea:a systemic review and meta-analysis

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Changes in cerebral metabolites in obstructive sleep apnea:a...

中国睡眠研究会第九届学术年会

作者： yunyan xia Yiqun Fu Huajun Xu Jian Guan Hongliang Yi Shankai Yin Department of Otolaryngology Head and Neck Surgery&Center of Sleep Medicine Shanghai Jiao Tong University Affiliated Sixth People's Hospital Otolaryngological Institute of Shanghai Jiao Tong University Clinical Research Center Shanghai Jiao Tong University School of Medicine

Background Cognitive impairment is associated with changes in cerebral metabolites in patients with obstructive sleep apnea（OSA）.Severalstudies have used magnetic resonance spectroscopy（MRS） to detect variations incerebral metabolites;however,the results have been *** meta-analysissummarizesthe differences in cerebral metabolites between patients with OSA and *** Two electronic databases,PubMed andEmbase,were searched for articles（published before March 31,2016） describing studies that used MRS to evaluate the cerebral metabolite *** overall effects were measured using the weighted mean difference with a 95%confidence *** analysis and sensitivity analysis were used to explore the sources of between-study heterogeneity and the stability of the *** bias was also *** Thirteen studies were ultimately *** the hippocampus,the N-acetylaspartate（NAA）/creatine ratio was lower in patients with *** the frontal lobe,only the NAA/choline ratio was lower in patients with *** Cerebral metabolites are significantly altered in the hippocampus in patients with *** clinical studies are needed to explore the underlying mechanisms between OSA and the changes in cerebral metabolites in the brain.

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Excessive Daytime Sleepiness and Metabolic syndrome in Men with Obstructive Sleep Apnea:a large cross-sectional study

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Excessive Daytime Sleepiness and Metabolic syndrome in Men w...

中国睡眠研究会第九届学术年会

作者： Yiqun Fu yunyan xia Hongliang Yi Huajun Xu Jian Guan Shankai Yin Department of Otolaryngology Head and Neck Surgery & Center of Sleep Medicine Shanghai Jiao Tong University Affiliated Sixth People's Hospital Otolaryngological Institute of Shanghai Jiao Tong University Clinical Research Center Shanghai Jiao Tong University School of Medicine

Purpose Excessive daytime sleepiness(EDS),a cardinal feature of obstructive sleep apnea(OSA),contributes to decreased productivity and increased risk of occupational *** may also relate to the metabolic syndrome(MetS).The aim of this cross-sectional study was to examine the role of EDS in metabolic dysfunction and the relation between EDS and MetS in men with *** The records of 2241 consecutive male participants who underwent standard polysomnography(PSG) were *** daytime sleepiness was assessed by using the Epworth sleepiness scale(ESS).Anthropometric,metabolic and polysomnographic parameters were *** Compared to non-EDS ones,males with both EDS and OSA seemed to be more obese,had higher blood pressure,more severe insulin resistance,dyslipidemia and lower LSpO(p<0.05).The metabolic score was significantly higher in the EDS group among severe OSA subjects(3.01±1.16 vs2.67±1.19,p<0.01).After adjustment for confounders,ESS score,BMI,Log ODI,age,smoking and alcoholism significantly predicted the metabolic score(P=0.049,p=0.020;p=0.367,p=0.000;P=0.221,p=0.000;P=0.084,p=0.000;P=0.063,p=0.002;P=-0.051,p=0.011,respectively).ConclusionsEDS was independently correlated with metabolic syndrome in men with *** study suggested that EDS patients should be comprehensively assessed for metabolic dysregulation.

关键词： Obstructive sleep apnea excessive daytime sleepiness dyslipidemia metabolic syndrome

Obstructive Sleep Apnea and Peripheral Arterial Disease:Evidence and potential mechanisms

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Obstructive Sleep Apnea and Peripheral Arterial Disease:Evid...

中国睡眠研究会第九届学术年会

Purpose Obstructive sleep apnea（OSA） is associated with cardiovascular *** has been proposed as an intermediate between OSA and incident cardiovascular *** arterial disease（PAD） is a manifestation of atherosclerosis in the vascular bed of the lower extremity *** aimed to summarize the relationship between OSA and PAD and discuss the potential pathophysiological *** Two electronic databases,PubMed andEMBASE,were searched for articles（published before April 2016） describing studies that evaluated association between among OSA,atherosclerosis and *** showed the results involved in the association in clinical and rodent *** Six clinical studies（five cross-sectional and one case-control） have investigated the association between PAD and OSA and established a bidirectional *** rodent studies revealed that intermittent hypoxia induced by OSA played a central role in promoting *** From clinical and rodent perspectives,we conclude that there is a positive association among OSA,atherosclerosis,and *** prospective,randomized controlled studies are needed to establish the cause-effect relationships involved.

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Prevalence and Predictors of Atherogenic Serum Lipoprotein Dyslipidemia in Women with Obstructive Sleep Apnea

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Prevalence and Predictors of Atherogenic Serum Lipoprotein D...

中国睡眠研究会第九届学术年会

Background It is well known that obstructive sleep apnea（OSA） is associated with ***,no current study mainly focused on dyslipidemia in women with OSA was *** aim of this study was to determine the prevalence and risk factors for dyslipidemiain these *** In total,570 female suspected-OSA participants were recruited from the Shanghai Sleep Health Study（SSHS） during *** polysomnography（PSG） parameters,biochemical indicators and anthropometric measurements were *** of dyslipidemia was compared between OSA and *** logistic regressionand multivariate linear regression models were used to determine the independent risk factors which could influence serum lipids in women with *** Compared with non-OSA,women with OSA had higher percentages of dyslipidemia of total cholesterol（TC）,triglycerides（TG） and low-density lipoprotein cholesterol（LDL-C）,apolipoprotein（apo） B and *** analysis showed that prevalence of dyslipidemia in OSA and non-OSA only presented difference in non-obese category and over 55 years-old *** circumference/hip circumference ratio（WHR）（OR=1.67,P=0.04） and lowest oxygen saturation（ODI）（OR=1.05,P=0.02） were independently associated ***,BMI and WHR were major independent factors for most serum lipid disorders after multivariate *** Women with OSApresent higher prevalence of dyslipidemiathan *** and obesity/central obesity were major determinants in serum lipid levels and dyslipidemia after multivariate adjustments.

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Meta-Analysis of All-cause and Cardiovascular Mortality in Obstructive Sleep Apnea With or Without Continuous Positive Airway Pressure Treatment

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Meta-Analysis of All-cause and Cardiovascular Mortality in O...

中国睡眠研究会第九届学术年会

＜正＞Purpose The associations between obstructive sleep apnea（OSA）and all-cause and cardiovascular mortality are well established but are not entirely *** accurately evaluate these associations as well as the therapeutic effects of continuous positive airway pressure（CPAP）,we conducted a comprehensive meta-analysis of all eligible cohort *** Electronic literature databases（i.e.,PubMed and Embase）were searched for relevant

关键词： obstructive sleep apnea all-cause mortality cardiovascular mortality meta-analysis

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米拉贝隆的合成工艺改进

中国药科大学学报 2020年第4期51卷 449-453页

作者：韩成群邹巧根孙茜夏云燕南京工业大学药学院南京211800

米拉贝隆是一种β-3肾上腺素受体的激动剂,用于治疗膀胱过度活动症。本研究在文献方法的基础上,对米拉贝隆的合成工艺进行了改进。以盐酸对硝基苯乙胺、(R)-扁桃酸和2-氨基噻唑-4-乙酸为起始原料,经过酰胺缩合、羰基还原、硝基还原及酰... 详细信息

米拉贝隆是一种β-3肾上腺素受体的激动剂,用于治疗膀胱过度活动症。本研究在文献方法的基础上,对米拉贝隆的合成工艺进行了改进。以盐酸对硝基苯乙胺、(R)-扁桃酸和2-氨基噻唑-4-乙酸为起始原料,经过酰胺缩合、羰基还原、硝基还原及酰胺缩合4步反应以及一步精制,得到高纯度的目标产物,总收率39%。将第3步硝基还原的氢源,由氢气改为了甲酸铵,增加了工业化可行性;并且对米拉贝隆的精制进行了研究,提高了米拉贝隆的纯度。改进后的工艺操作简化,反应条件温和,为米拉贝隆的制备和精制提供了一种新的方法。

关键词：米拉贝隆膀胱过度活动症硝基还原工艺改进合成

紧凑型高压电机起动特性及阻抗的电磁耦合计算

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电工技术学报 2017年第1期32卷 183-189页

作者：夏云彦孟大伟于清明于晓洋哈尔滨理工大学电气与电子工程学院哈尔滨150080 哈尔滨理工大学仪器科学与技术博士后科研流动站哈尔滨150080 江苏华朋集团有限公司溧阳213300

针对紧凑型高压感应电机动态阻抗及起动特性不易通过实验测取的问题,对电机起动过程中的起动特性、饱和效应与趋肤效应之间的相互影响关系进行分析,根据电机具体结构,对现有模型和算法进行改进,并从实用角度出发,建立相互耦合的电机磁... 详细信息

针对紧凑型高压感应电机动态阻抗及起动特性不易通过实验测取的问题,对电机起动过程中的起动特性、饱和效应与趋肤效应之间的相互影响关系进行分析,根据电机具体结构,对现有模型和算法进行改进,并从实用角度出发,建立相互耦合的电机磁网络模型、分层法模型和动态数学模型。对耦合模型进行求解,实现了整个起动过程电机动态参数的计算。分析了阻抗变化对电机起动特性的影响。用有限元法和实测法验证了计算模型的准确性,可实现电机的系列化计算。

关键词：紧凑型高压电机动态阻抗起动特性磁网络趋肤效应