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Characteristics of brainstem auditory evoked potentials of students studying folk dance

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Neural Regeneration Research 2008年第2期3卷 225-228页

作者： yunxiang li Yuzhen Zhu Physical Education College Linyi Normal University Linyi 276005 Shandong Province China

BACKGROUND： Previous experiments have demonstrated that brainstem auditory evoked potential is affected by exercise, exercise duration, and frequency. OBJECTIVE： Comparing the brainstem auditory evoked potential of students studying folk dance to students studying other subjects. DESIGN： Observational contrast study. SETTING： Physical Education College, Shandong Normal University PARTICIPANTS： Fifty-five female students were enrolled at Shandong Normal University between September and December in 2005, including 21 students that studied folk dance and 34 students that studied other subjects. The age of the folk dance students averaged （19 ± 1） years and dance training length was （6.0 ± 1.5） years. The students that studied other subjects had never taken part in dance training or other physical training, and their age averaged （22 ± 1） years, body height averaged （162 ± 5） cm, body mass averaged （51 ± 6） kg. All subjects had no prior ear disease or history of other neurological disorders. All students provided informed consent for the experimental project. METHODS： The neural electricity tester, NDI-200 （Shanghai Poseidon Medical Electronic Instrument Factory） was used to examine and record Brainstem Auditory Evoked Potential values of the subjects during silence, as well as to transversally analyze the Brainstem Auditory Evoked Potential values. The electrode positions were cleaned and degreased with soapy water, followed by ethanol. The selected bipolar electrodes were situated on the head： recording electrodes were placed at the Baihui acupoint, and the reference electrode was placed at the mastoid of the measured ear, with grounding electrodes in the center of the forehead. Brainstem Auditory Evoked Potential values were elicited by monaural stimulation of a ＂click＂ though an earphone; the other ear was sheltered by the white noise. The click intensity was 102 db, the stimulation frequency was 30 Hz, the bandpass filters were 1 000-3 000 Hz, the sensitivity

关键词： brainstem auditory evoked potential peak latency peak-peak value folk dance

Appropriate stimulation in visual evoked potential to evaluate visual perception state of athletes

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Neural Regeneration Research 2008年第6期3卷 666-669页

作者： yunxiang li Yuzhen Zhu Physical Education College Linyi Normal University Linyi 276005 Shandong Province China

BACKGROUND： Several studies have demonstrated that visual evoked potentials can be influenced by sport events. To the best of our knowledge, there are no specific parameters for the most appropriate stimulation for evaluating the functional state of athletes. OBJECTIVE： To investigate the best stimulation in visual evoked potential to apply to functional evaluation of athletes. DESIGN, TIME AND SETTING： Ninety-five, healthy students from the Shandong Normal University took part in an observational, contrast study. PARTICIPANTS： All active participants were male. Sixty-five students majored in physical education, and had participated in exercise for the duration of （4.26 ± 3.08） years. An additional 30 students majored in other subjects. METHODS： The neural electricity tester, NDI-200, was adapted to examine and record visual evoked potential with varying probes using bipolar electrodes attached to the head of all the participants in a dark room. The visual evoked potential values were analyzed transversally. A chessboard pattern reversal method was applied with the following parameters： 2 Hz stimulation frequency, brightness of 90 cdp, 80% contrast, 1-100 Hz bandpass filters, and 10 μV sensitivity; 100 responses were averaged. MAIN OUTCOME MEASURES： latency, peak latencies, and inter-peak latencies were measured in N75, P100, N145 with varying probe stimulations. RESULTS：（1） Comparisons between the little check, middle check, and big check stimulation, demonstrated that the common tendencies in visual evoked potential indexes of the two groups of N75 latency were successively shorter and N145 were longer. P100-N145 peak latency was decreased and each inter-peak latency was longer. （2） Changes of N75, P100, and N145 with different check stimulations in the physical education student group： after compared with the middle check stimulation, N75 latency was significantly longer （P 〈 0.01）, and N75-P100 inter-peak latency （P 〈 0.05） and N75-N145 inter-peak latency were

关键词： visual evoked potential functional evaluation probe stimulation

Effects of Flowering Mode and Pollinator Sharing on Reproductive Success in Natural Hybrid of Two Epimedium(Berberidaceae)Species

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Phyton-International Journal of Experimental Botany 2024年第3期93卷 551-566页

作者： Lanying Chen Qiumei Quan yunxiang li College of life Sciences China West Normal UniversityNanchong637000China School of Ecology and Environment Tibet UniversityLasha850000China College of Environment Science and Engineering China West Normal UniversityNanchong637000China

Mediated by pollenﬂow,natural hybridization is deemed a crucial factor that propels speciation inﬂoral *** the fact that the diversity of Epimedium species is concentrated mainly in Southwestern China,the poten-tial impact of interspeciﬁc pollination on natural hybridization has yet to be empirically *** explore this,we studied theﬂowering period and the visitors ofﬂowers in three frequently overlapping Epimedium species at Jinchengshan National Forest Park,located in Nanchong,Sichuan ***,we performed a ser-ies of pollination experiments to examine breeding systems and hybrid ***,Epime-dium pubescens and Epimedium wushanense are clearly distinct and easily recognizable byﬂower morphology,while the putative hybrid is morphologically intermediate between *** observation revealed that ***-escens and *** had 15 days of overlapping *** species are self-incompatible and require pol-linator services for successful *** their pollinators differ in quantity and species,Lasioglossum sp.(Hymenoptera:Halictidae)visited all three ***ﬁcial pollination revealed no breeding barriers among the three species,and the resulting hybrid seeds exhibited *** overlapping time ofﬂowering,commonﬂoral visitors,and compatibility of hybrids may be important factors contributing to successful interspeciﬁc pol-lination and speciation for natural hybrid species of *** and ***,the role of potential interspeciﬁc pollination is crucial for hybrid speciation and the evolutionary dynamics of Epimedium species.

关键词： Breeding system ﬂoral visitor medicinal plant species evolution

A New Algorithm for Sparse Frequency Waveform Design with Range Sidelobes Constraint

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Chinese Journal of Electronics 2015年第3期24卷 604-610页

作者： WU Hao SONG Zhiyong FAN Hongqi li yunxiang FU Qiang ATR National University of Defense Technology

To suppress narrowband interferences,sparse frequency waveform can be transmitted by wideband radar systems. It suffers the high range sidelobes. A new algorithm for sparse frequency waveform design with range sidelobes constraint is proposed. The approach affords much better frequency stopband suppression by flexibly controlling sidelobes constraint using Weighted integrated sidelobe level(WISL) metric. The approach is computationally efficient and can suit the more general Peakto-average power ratio(PAR) constraint. An extension to Multiple-input multiple-output(MIMO) radar case is also presented.

关键词： Cognitive radar Sparse frequency waveform Weighted integrated sidelobe level(WISL) PAR

Improving prodeoxyviolacein production via multiplex SCRaMbLE iterative cycles

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Frontiers of Chemical Science and Engineering 2018年第4期12卷 806-814页

作者： Juan Wang Bin Jia Zexiong Xie yunxiang li Yingjin Yuan Key Laboratory of Systems Bioengineering (Ministry of Education) School of Chemical Engineering and Technology Tianjin UniversityTianjin 300072China SynBio Research Platform Collaborative Innovation Center of Chemical Science and Engineering (Tianjin)Tianjin University Tianjin 300072China

The synthetic chromosome rearrangement and modification by loxP-mediated evolution (SCRaMbLE) system has been used to improve prodeoxyviolacein (PDV) production in haploid yeast containing chromosome synV. To rapidly and continuously generate genome diversification with the desired phenotype, the multiplex SCRaMbLE iterative cycle strategy has been developed for the screening of high PDV production strains. Wholegenome sequencing analysis reveals large duplications, deletions, and even the whole genome duplications. The deletion of YER151C is proved to be responsible for the increase. This study demonstrates that artificial DNA rearrangement can be used to accelerate microbial evolution and the production of biobased chemicals.

关键词： synthetic biology genome rearrangement prodeoxyviolacein SCRaMbLE Saccharomyces cerevisiae

Loss of heterozygosity by SCRaMbLEing

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Science China(life Sciences) 2019年第3期62卷 381-393页

作者： yunxiang li Yi Wu Lu Ma Zhou Guo Wenhai Xiao Yingjin Yuan Frontier Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education) Tianjin University Collaborative Innovation Center of Chemical Science and Engineering (Tianjin) School of Chemical Engineering and Technology Tianjin University

Genetic variation drives phenotypic evolution within populations. Genetic variation can be divided into different forms according to the size of genomic changes. However, study of large-scale genomic variation such as structural variation and aneuploidy is still limited and mainly based on the static, predetermined feature of individual genomes. Here, using SCRaMbLE,different levels of loss of heterozygosity(LOH) events including short-range LOH, long-range LOH and whole chromosome LOH were detected in evolved strains. By contrast, using rapid adaptive evolution, aneuploidy was detected in the adaptive strains. It was further found that deletion of gene GLN3, long-range LOH in the left arm of synthetic chromosome Ⅹ, whole chromosome LOH of synthetic chromosome Ⅹ, and duplication of chromosome Ⅷ(trisomy) lead to increased rapamycin resistance in synthetic yeast. Comparative analysis of genome stability of evolved strains indicates that the aneuploid strain has a higher frequency of degeneration than the SCRaMbLEd strain. These findings enrich our understanding of genetic mechanism of rapamycin resistance in yeast, and provide valuable insights into yeast genome architecture and function.

关键词： SCRaMbLE loss of heterozygosity(LOH) rapid adaptive evolution aneuploidy structural variation synthetic yeast genome

Middle Pleistocene mammalian fauna of Shanyangzhai cave in Qinhuangdao area, China and its zoogeographical significance

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Chinese Science Bulletin 2010年第21期55卷 72-76页

作者： ZHANG yunxiang li YongXiang WANG Wei GONG HuJun State Key Laboratory of Continental Dynamics Department of Geology Northwest University Xi'an 710069 China

The mammalian fauna with clear characteristics of transitional region has been found in the Shanyangzhai cave of the Qin-huangdao area where the three Chinese zoogeographical regions (the Northeast region, the North region and the Mengxin region) join. Abundant fossils mainly are small mammals. The fauna includes typical species derived from three zoogeographical regions and can be compared with the middle Pleistocene faunas found in both the Zhoukoudian (the North region) and the Jinniushan (the Northeast region) faunas. Of 53 kinds of mammals identified at the site, 38 kinds can be seen on the list of the middle Pleis-tocene Zhoukoudian and the Jinniushan faunas, of which 29 kinds are the same as those in the Zhoukoudian fauna and 25 are in the Jinniushan fauna, 7 in the Salawusu fauna and account for 76%, 66% and 18% of the total, respectively. It is suggested based on the consistence of the constitution of the fauna and its recent zoogeographic division that the three regions in north China could be initially formed during the middle Pleistocene.

关键词：哺乳动物群秦皇岛地区中更新世中国洞穴地理学小型哺乳动物东北地区

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Perfluoropentane-based oxygen-loaded nanodroplets reduce microglial activation through metabolic reprogramming

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Neural Regeneration Research 2025年第4期20卷 1178-1191页

作者： Wanxian Luo Chuanhui Xu linxi li yunxiang Ji Yezhong Wang Yingjia li Yongyi Ye Department of Medicine Ultrasonics Nanfang HospitalSouthern Medical UniversityGuangzhouGuangdong ProvinceChina Institute of Neuroscience Department of NeurosurgeryThe Second Affiliated Hospital of Guangzhou Medical UniversityGuangzhouGuangdong ProvinceChina

Microglia,the primary immune cells within the brain,have gained recognition as a promising therapeutic target for managing neurodegenerative diseases within the central nervous system,including Parkinson’s *** perfluorocarbon droplets have been reported to not only possess a high oxygen-carrying capacity,but also exhibit remarkable anti-inflammatory ***,the role of perfluoropentane in microglia-mediated central inflammatory reactions remains poorly *** this study,we developed perfluoropentane-based oxygen-loaded nanodroplets(PFP-OLNDs)and found that pretreatment with these droplets suppressed the lipopolysaccharide-induced activation of M1-type microglia in vitro and in vivo,and suppressed microglial activation in a mouse model of Parkinson’s *** suppression led to a reduction in the inflammatory response,oxidative stress,and cell migration capacity in ***,the neurotoxic effects were mitigated,which alleviated neuronal ***,ultrahigh-performance liquid chromatography–tandem mass spectrometry showed that the anti-inflammatory effects of PFP-OLNDs mainly resulted from the modulation of microglial metabolic *** further showed that PFP-OLNDs regulated microglial metabolic reprogramming through the AKT-mTOR-HIF-1α***,our findings suggest that the novel PFP-OLNDs constructed in this study alleviate microglia-mediated central inflammatory reactions through metabolic reprogramming.

关键词： metabolic reprogramming microglia microglial migration nanotherapy neurodegenerative diseases neuroinflammation oxygen-loaded nanodroplets Parkinson’s disease perfluoropentane ultra-performance liquid chromatography–mass spectrometry

Epoxidation of olefins with hydrogen peroxide catalyzed by a reusable lacunary-type phosphotungstate catalyst

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Science China Chemistry 2011年第5期54卷 769-773页

作者： HUA li,QIAO yunxiang,li Huan,FENG Bo,PAN ZhenYan,YU YinYin,ZHU WenWen & HOU ZhenShan Key Laboratory for Advanced Materials Research Institute of Industrial Catalysis,East China University of Science and Technology,Shanghai 200237,China Key Laboratory for Advanced Materials Research Institute of Industrial Catalysis East China University of Science and Technology Shanghai China

Olefins and allylic alcohols have been epoxidized with commercially available hydrogen peroxide (30% H2O2) using a phase transfer catalyst,composed of cetyltrimethylammonium cations and a lacunary-type phosphotungstate anion [PW11O39]7-or the complete Keggin-type heteropolyanion [PW12O40]3-,under two-phase conditions using ethyl acetate as the solvent. It was found that the lacunary-type catalyst showed higher activity and better recyclability than the complete Keggin-type catalyst under the same reaction conditions. 31P NMR spectroscopy and solubility measurements for the two catalysts revealed that the [PW11O39]7-anion had a much faster degradation rate than the [PW12O40]3-anion in an excess of H2O2,which resulted in the formation of more catalytically active species. As a result,the lacunary-type phosphotungstate anion-based catalyst gave a better catalytic performance than the complete Keggin-type anion in ethyl acetate.

关键词： heteropolyphosphotungstate lacunary epoxidation degradation rate