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A Comprehensive Study on the Consequences of Gap-Graded Sands Considering the Loss of Fine Particles

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Journal of Earth Science 2024年第2期35卷 597-612页

作者： Weiping Liu Yu Gan yunwei Cui Faming huang Lina hu School of Civil Engineering and Architecture Nanchang UniversityNanchang330031China

Water and sand leakage disasters are likely to occur during construction in water-rich sand layer areas,resulting in ground *** stress-strain action characteristics of discontinuous graded sand under different internal erosion degrees,and the evolution mechanism of water and sand leakage disasters caused by the internal erosion need to be further ***,this paper takes the discontinuous graded sand in a water rich sand layer area in Nanchang City of China as the research *** the influence of different fine particle losses(0,10%,20%and 30%)under the internal erosion of sand,the salt solution method is used to realize the specified loss of fine particles in the internal *** stress-strain behavior after the loss of fine particles due to internal erosion is studied by triaxial shear ***,the physical model test and PFC-CFD method are both used to study the evolution rules of water and sand leakage disaster considered the influence of internal erosion *** show that:(1)under the same confining pressure,the peak failure strength of sand samples decreases along with the increase of fine particle loss.(2)In the water and sand leakage test of saturated sand,a natural filter channel is formed above the observed soil *** greater the loss of fine particles,the steeper and wider the collapse settlement area.(3)The relationship between the cumulative amount of water and sand leakage and time is *** total mass loss of sand increases along with the increase of internal erosion degree.(4)After the soil arch is formed around the damaged opening,the sand continues to converge above the soil arch under the action of water flow,resulting in the dense convergence of contact force chains.

关键词： sandy soil internal erosion stress and strain water and sand leakage PFC3D engineering geology

Diagnostic value of genetic mutation analysis and mutation profiling of cell-free DNA in intraocular fluid for vitreoretinal lymphoma

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Cancer Communications 2022年第11期42卷 1217-1221页

作者： Xiaoqing Chen yunwei hu Wenru Su Shizhao Yang Xiaoxiao Wang Ping Zhang Xiaoyu Hong Chuqiao Liang Zhuyun Qian Ziqiang Li Yong Tao huiqiang huang Dan Liang State Key Laboratory of Ophthalmology Zhongshan Ophthalmic CenterSun Yat-sen UniversityGuangdong Provincial Key Laboratory of Ophthalmology and Visual ScienceGuangdong Provincial Clinical Research Center for Ocular DiseasesGuangzhouGuangdongP.R.China Department of Medical Oncology Sun Yat-sen University Cancer CenterGuangzhouGuangdongP.R.China Department of Ophthalmology Beijing Chaoyang HospitalCapital Medical UniversityBeijingP.R.China Nanjing Geneseeq Technology Inc. NanjingJiangsuP.R.China Beijing GIANTMED Medical Diagnostics Lab BeijingP.R.China

Dear editor,Vitreoretinal lymphoma(VRL)is a rare intraocular malignant lymphoma affecting the vitreous and/or *** diagnosis is *** biopsies have high risks of irreversible visual impairment(even blind-ness),which are not used in clinics for patients with residual visual *** limited cellular yield from vit-reous biopsies and the cell lysis also contribute to the low detection rates of VRL using cytopathology[1].

关键词： lymphoma intraocular diagnosis

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急性黄斑神经视网膜病变1例

中华眼科杂志 2023年第11期59卷 937-939页

作者：汪月胡云薇殷小龙邓燕南昌大学第二附属医院眼科中心南昌330006

16岁女性患者在感染新型冠状病毒后发生双眼视力急剧下降伴眼前黑影5 d。进行眼部检查评估,相干光层析成像术的结构平面成像显示指向黄斑中心凹的低反射楔形病灶,B扫描图像可见视网膜外核层及光感受器层的局限性高反射条带,椭圆体带不... 详细信息

16岁女性患者在感染新型冠状病毒后发生双眼视力急剧下降伴眼前黑影5 d。进行眼部检查评估,相干光层析成像术的结构平面成像显示指向黄斑中心凹的低反射楔形病灶,B扫描图像可见视网膜外核层及光感受器层的局限性高反射条带,椭圆体带不连续。根据临床表现及检查结果,诊断为双眼急性黄斑神经视网膜病变。

关键词：白点综合征体层摄影术光学相干新型冠状病毒感染

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企业财务转型升级路径

中国冶金教育 2023年第6期 121-124页

作者：胡芸玮孙海涛青岛理工大学财务处山东青岛266520

中国经济已经由高速增长阶段转向高质量发展阶段,企业转型升级必然需要财务的转型升级,财务工作需要与企业的规模、管理模式与管理水平相匹配。通过组织方式变革、业财融合及信息共享平台建设构建企业财务转型路径,促进企业高质量发展。

关键词：财务转型财务共享中心业财融合

Climate Sensitivity and Feedbacks of BCC-CSM to Idealized CO2 Forcing from CMIP5 to CMIP6

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Journal of Meteorological Research 2020年第4期34卷 865-878页

作者： Xueli SHI Xiaolong CHEN yunwei DAI Guoquan hu National Climate Center China Meteorological AdministrationBeijing 100081 State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029 CAS Center for Excellence in Tibetan Plateau Earth Sciences Chinese Academy of Sciences(CAS)Beijing 100101 huafeng Meteorological Media Group China Meteorological AdministrationBeijing 100081

Climate sensitivity represents the response of climate system to doubled CO2 concentration relative to the preindustrial level, which is one of the sources of uncertainty in climate projections. It is unclear how the climate sensitivity and feedbacks will change as a model system is upgraded from the Coupled Model Intercomparison Project Phase 5(CMIP5) to CMIP6. In this paper, we address this issue by comparing two versions of the Beijing Climate Center Climate System Model(BCC-CSM) participating in CMIP6 and CMIP5, i.e., BCC-CSM2-MR and BCC-CSM1.1 m,which have the same horizontal resolution but different physical parameterizations. The results show that the equilibrium climate sensitivity(ECS) of BCC-CSM slightly increases from CMIP5(2.94 K) to CMIP6(3.04 K). The small changes in the ECS result from compensation between decreased effective radiative forcing(ERF) and the increased net feedback. In contrast, the transient climate response(TCR) evidently decreases from 2.19 to 1.40 K, nearly the lower bound of the CMIP6 multimodel spread. The low TCR in BCC-CSM2-MR is mainly caused by the small ERF overly even though the ocean heat uptake(Ohu) efficiency is substantially improved from that in BCC-CSM1.1 *** shortwave feedback(λSWCL) is found to be the major cause of the increased net feedback in BCC-CSM2-MR,mainly over the Southern Ocean. The strong positive λSWCL in BCC-CSM2-MR is coincidently related to the weakened sea ice-albedo feedback in the same region. This result is caused by reduced sea ice coverage simulated during the preindustrial cold season, which leads to reduced melting per 1-K global warming. As a result, in BCCCSM2-MR, reduced surface heat flux and strengthened static stability of the planetary boundary layer cause a decrease in low-level clouds and an increase in incident shortwave radiation. This study reveals the important compensation between λSWCL and sea ice-albedo feedback in the Southern Ocean.

关键词： Beijing Climate Center Climate System Model(BCC-CSM) climate sensitivity cloud feedback sea icealbedo feedback Coupled Model Intercomparison Project Phase 6(CMIP6)

Performance of K-ras mutation analysis plus endoscopic ultrasound- guided fine-needle aspiration for differentiating diagnosis of pancreatic solid mass： a meta-analysis

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Chinese Medical Journal 2014年第18期127卷 3296-3301页

作者： Xu Ying hu Duanmin Zhu Qi Sun yunwei Department of Gastroenterology Ruijin Hospital Shanghai Jiao TongUniversity School of Medicine Shanghai 200025 China Xinhua Hospital Shanghai Jiao Tong University School of MedicineShanghai 200092 China Department of Gastroente-rology Second Affiliated Hospital ofSoochow University Suzhou Jiangsu 215004 China

Background Difficulties persist in differentiating pancreatic ductal adenocarcinomas （PDAC） from pancreatic inflammatory masses （PIM）. Auxiliary diagnostic techniques which enhance the endoscopic ultrasound-guided fine-needle aspiration （EUS-FNA） diagnostic yield have been attempted, for example, K-ras mutation analysis. We aimed to evaluate the accuracy of K-ras mutation analysis combined with EUS-FNA for the differential diagnosis of PDAC and PIM by pooling data of existing trials. Methods We systematically searched the Medline, PubMed, Web of Science, Embase, and Cochrane Central Trials databases for relevant published studies. Meta-analysis was performed. Pooling was conducted in fixed-effect model or random-effect model. Results In total eight studies, with 696 cases of PDAC and 138 cases of PIM, met our inclusion criteria. The pooled sensitivity, specificity, positive likely ratio and negative likely ratio of K-ras mutation analysis combined with cytopathology for diagnosis of PDAC versus PIM were 90%, 95%, 13.45, and 0.13, respectively. Especially, among total 123 patients whose EUS-FNA results were inconclusive or negative, fifty-nine had K-ras mutations and were finally diagnosed with PDAC （48%, 59/123）. Publication bias was not present. Conclusions Combining K-ras mutation analysis with routine cytology moderately improves the ability of EUS-FNA to differentially diagnose between PDAC and PIM, especially for patients with suspected PDAC yet inconclusive EUS-FNA findings, and may prove to be a valuable supplemental method to EUS-FNA.

关键词： endoscopic ultrasonography diagnosis pancreatic ductal adenocarcinoma K-ras mutation analysis

Exploiting H-induced lattice expansion in β-palladium hydride for enhanced catalytic activities toward oxygen reduction reaction

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Journal of Materials Science & Technology 2022年第3期98卷 205-211页

作者： yunwei Liu Zelin Chen Chang Liu Jinfeng Zhang Wenbin hu Yida Deng Tianjin Key Laboratory of Composite and Functional Materials School of Materials Science and EngineeringTianjin UniversityTianjin 300372China State Key Laboratory of Marine Resource Utilization in South China Sea School of Materials Science and EngineeringHainan UniversityHaikou 570228China

We have developed an efficient strategy to synthesize an active and durable electrocatalyst of Pd hydride nanocubes(NCs).Instead of the traditional chemical method,the PdH_(0.43)NCs are firstly prepared via a hydrogen diffusion procedure,followed by hydrothermal synthesis of an amorphous CuO layer encapsulating the PdH_(0.43)NCs to prevent the hydrogen atoms from *** lattice expansion is demonstrated playing a pivotal role in the enhancement of their oxygen reduction reaction(ORR)activity and *** obtained PdH_(0.43)@CuO NCs catalysts exhibit an ORR mass activity of 0.18 A mg^(−1) at 0.90 V versus reversible hydrogen electrode in an alkaline medium,which is about five times higher than that of commercial Pt/*** durability tests show that there is only a 32 mV decay in halfwave potential even after 10,000 potential cycles,indicating the excellent stability of PdH_(0.43)@CuO *** functional theory(DFT)calculations also indicate that,compared to Pd,PdH_(0.43)has a lower limiting barrier to form OH−during the ORR *** present study illustrates the importance of lattice expansion caused by hydrogen and offers an available strategy to design highly efficient and durable Pdbased electrocatalysts for alkaline fuel cells.

关键词： Lattice expansion Pd hydride Amorphous CuO Elecrocatalysis Oxygen reduction reaction

配电网自动化终端自适应托管式调试系统设计与实践

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电工技术 2024年第13期 71-76,81页

作者：林运伟胡波叶剑辉王振华珠海许继芝电网自动化有限公司广东珠海519000

建立了一套基于最新计算机网络及软件技术,符合104标准通信规约,面向供电公司自动化和运检专业需求,并服务于配电自动化终端接入的自适应托管式终端联调系统。该系统将联调过程由联调系统与现场联调装置自动交互完成,既可保障联调工作... 详细信息

建立了一套基于最新计算机网络及软件技术,符合104标准通信规约,面向供电公司自动化和运检专业需求,并服务于配电自动化终端接入的自适应托管式终端联调系统。该系统将联调过程由联调系统与现场联调装置自动交互完成,既可保障联调工作标准化,又能缩短联调时间,节省各项成本。该系统的搭建,对于规范自动化终端接入联调以及联调工作的提质增效具有重要的实践意义。

关键词：配电自动化联调传动托管式调试联调任务单联调报告

收肌管阻滞联合腘动脉-膝关节囊后间隙阻滞或胫神经阻滞在全膝关节置换术中的应用

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临床麻醉学杂志 2021年第3期37卷 229-232页

作者：王春光刘蕊李艳军李永旺王旭伟胡蕴伟李艳青赵景河北省保定市第一中心医院麻醉科 071000 河北省保定市第一中心医院骨科 071000 河北省保定市第一中心医院手术室 071000 河北省保定市第一中心医院医学影像科 071000 承德医学院保定市妇幼保健院麻醉科

目的比较收肌管阻滞(ACB)联合腘动脉-膝关节囊后间隙阻滞(IPACK)或选择性胫神经阻滞(TNB)用于全膝关节置换术的镇痛效果及对运动功能的影响。方法选择2020年4—6月行全膝关节置换术老年患者60例,男28例,女32例,年龄65~84岁,ASAⅡ或Ⅲ级... 详细信息

目的比较收肌管阻滞(ACB)联合腘动脉-膝关节囊后间隙阻滞(IPACK)或选择性胫神经阻滞(TNB)用于全膝关节置换术的镇痛效果及对运动功能的影响。方法选择2020年4—6月行全膝关节置换术老年患者60例,男28例,女32例,年龄65~84岁,ASAⅡ或Ⅲ级。采用随机数字表法分为两组:IPACK组(I组)和TNB组(T组)。I组于术前采用含肾上腺素0.1 mg的0.25%罗哌卡因20 ml行IPACK,T组于术前采用含肾上腺素0.1 mg的0.25%罗哌卡因20 ml行TNB。I组与T组完成IPACK或TNB后行ACB,并留置神经周围导管,术后连接患者自控神经阻滞镇痛泵。术后VAS疼痛评分>4分时,患者按压镇痛泵,30 min未缓解,皮下注射羟考酮5 mg进行补救镇痛。记录术后4 h腓总神经运动阻滞情况及术前、术后24、48、72 h静息、运动时VAS疼痛评分。记录术后1~3 d患者主动屈膝最大角度及步行距离。记录术后72 h内患者补救镇痛及不良事件发生情况。结果与T组比较,I组腓总神经运动阻滞率明显降低(P<0.05);术后1、2 d步行距离明显增加(P<0.05)。两组不同时点静息、运动时VAS疼痛评分、补救镇痛率、术后3 d步行距离及术后1~3 d主动屈膝最大角度差异无统计学意义。结论ACB联合IPACK或TNB均可为全膝关节置换术患者提供有效地术后镇痛,但IPACK对运动功能影响小于TNB。

关键词：腘动脉-膝关节囊后间隙阻滞胫神经阻滞收肌管阻滞全膝关节置换术