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International Journal of Mining Science and Technology 2023年第6期33卷 747-760页

作者： Qijian Chen Youliang Chen Peng Xiao Xi Du yungui pan Rafig Azzam Department of Civil Engineering School of Environment and ArchitectureUniversity of Shanghai for Science and TechnologyShanghai 200093China Department of Engineering Geology and Hydrogeology RWTH Aachen UniversityAachen 52064Germany School of Civil and Environmental Engineering University of New South WalesSydney 2052Australia

Aiming at the problem of temperature-mechanics-chemical(T-M-C)action encountered by rocks in underground engineering,sandstone was selected as the sample for acid corrosion treatment at pH 1,3,5 and 7,the acid corrosion treated samples were then subjected to high-temperature experiments at 25,300,600,and 900℃,and triaxial compression experiments were conducted in the laboratory.The experimental results show that the superposition of chemical damage and thermal damage has a significant impact on the quality,wave velocity,porosity and compression failure characteristics of the rock.Based on the Lemaitre strain equivalent hypothesis theory,the damage degree of rock material was described by introducing damage variables,and the spatial mobilized plane(SMP)criterion was adopted.The damage constitutive model can well reflect the stress-strain characteristics of the rock triaxial compression process,which verified the rationality and reliability of the model parameters.The experiment and constitutive model analyzed the change law of mechanical properties of rock after chemical corrosion and high temperature thermal damage,which had certain practical significance for rock engineering construction.

关键词： Acid corrosion High temperature Mechanical properties Damage variable SMP criterion Constitutive model

ACSL5,a prognostic factor in acute myeloid leukemia,modulates the activity of Wnt/β-catenin signaling by palmitoylation modification

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Frontiers of Medicine 2023年第4期17卷 685-698页

作者： Wenle Ye Jinghan Wang Jiansong Huang Xiao He Zhixin Ma Xia Li Xin Huang Fenglin Li Shujuan Huang Jiajia pan Jingrui Jin Qing Ling yungui Wang Yongping Yu Jie Sun Jie Jin Department of Hematology The First Affiliated HospitalZhejiang University College of MedicineHangzhou 310003China Key Laboratory of Hematopoietic Malignancies Diagnosis and TreatmentHangzhou 310009China Research Centre Centre hospitalier de l’Universitéde Montréal(CRCHUM)MontrealQuebec H2L 4M1Canada Women’s Hospital School of MedicineZhejiang UniversityHangzhou 310006China Zhejiang Province Key Laboratory of Anti-Cancer Drug Research College of Pharmaceutical SciencesZhejiang UniversityHangzhou 310058China Cancer Center Zhejiang UniversityHangzhou 310058China

Acyl-CoA synthetase long chain family member 5(ACSL5),is a member of the acyl-CoA synthetases(ACSs)family that activates long chain fatty acids by catalyzing the synthesis of fatty acyl-CoAs.The dysregulation of ACSL5 has been reported in some cancers,such as glioma and colon cancers.However,little is known about the role of ACSL5 in acute myeloid leukemia(AML).We found that the expression of ACSL5 was higher in bone marrow cells from AML patients compared with that from healthy donors.ACSL5 level could serve as an independent prognostic predictor of the overall survival of AML patients.In AML cells,the ACSL5 knockdown inhibited cell growth both in vitro and in vivo.Mechanistically,the knockdown of ACSL5 suppressed the activation of the Wnt/β-catenin pathway by suppressing the palmitoylation modification of Wnt3a.Additionally,triacsin c,a pan-ACS family inhibitor,inhibited cell growth and robustly induced cell apoptosis when combined with ABT-199,the FDA approved BCL-2 inhibitor for AML therapy.Our results indicate that ACSL5 is a potential prognosis marker for AML and a promising pharmacological target for the treatment of molecularly stratified AML.

关键词： acute myeloid leukemia acyl-CoA synthetase long chain family member 5 Wnt3a palmitoylation ABT-199

Substantial transition to clean household energy mix in rural China

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National Science Review 2022年第7期9卷 137-151页

作者： Guofeng Shen Rui Xiong Yanlin Tian Zhihan Luo Bahabaike Jiangtulu Wenjun Meng Wei Du Jing Meng Yuanchen Chen Bing Xue Bin Wang Yonghong Duan Jia Duo Fenggui Fan Lei Huang Tianzhen Ju Fenggui Liu Shunxin Li Xianli Liu yungui Li Mu Wang Ying Nan Bo pan Yanfang pan Lizhi Wang Eddy Zeng Chao Zhan Yilin Chen Huizhong Shen Hefa Cheng Shu Tao Xinjiang Key Laboratory of Environmental Pollution and Bioremediation Xinjiang Institute of Ecology and Geography Chinese Academy of Sciences National Engineering Technology Research Center for Desert-Oasis Ecological Construction Xinjiang Institute of Ecology and Geography Chinese Academy of Sciences University of Chinese Academy of Sciences School of Geography and Tourism Anhui University School of Environment Nanjing University College of Geography and Environmental Science Northwest Normal University College of Geographical Science Qinghai Normal University Academy of Plateau Science and Sustainability College of Chemistry Chemical Engineering and Environment Minnan Normal University School of Environmental Science and Engineering Hubei Polytechnic University College of Urban and Environmental Sciences Peking University Department of Environmental Engineering Southwest University of Science and Technology College of Food Science Tibet Agricultural and Animal Husbandry University College of Geography and Ocean Sciences Yanbian University Faculty of Environmental Science and Engineering Kunming University of Science and Technology College of Geography and Environmental Science Henan University College of Ecology and Environment Hainan University School of Environment Jinan University Institute of Coastal Research Ludong University College of Environmental Science and Technology Southern University of Science and Technology Collaborative Innovation Center of Atmospheric Environment and Equipment Technology Jiangsu Key Laboratory of Atmospheric Environment Monitoring and Pollution Control (AEMPC)Nanjing University of Information Science and Technology Institute of Reproductive and Child Health Peking University Laboratory of Geographic Information Science School of Geographic Sciences East China Normal University The Bartlett School of Sustainable Construction University College London College of Environment Zhejiang University of Technology Institute of Applied Ecology Chinese Academy of Sciences

The household energy mix has significant impacts on human health and climate,as it contributes greatly to many health-and climate-relevant air pollutants.Compared to the well-established urban energy statistical system,the rural hous ehold energy statistical system is incomplete and is often associated with high biases.Via a nationwide investigation,this study reve aled high contributions to energy supply from coal and biomass fuels in the rural household energy sector,while electricity comprised ～20%.Stacking(the use of multiple sources of energy) is significant,and the average number of energy types was 2.8 per household.Compared to 2012,the consumption of biomass and coals in 2017 decreased by 45% and 12%,respectively,while the gas consumption amount increased by 204%.Increased gas and decreased coal consumptions were mainly in cooking,while decreased biomass was in both cooking(41%) and heating(59%).The time-sharing fraction of electricity and gases(E&G) for daily cooking grew,reaching 69% in 2017,but for space heating,traditional solid fuels were still dominant,with the national average shared fraction of E&G being only 20%.The non-uniform spatial distribution and the non-linear increase in the fraction of E&G indicated challenges to achieving universal access to modern cooking energy by 2030,particularly in less-developed rural and mountainous areas.In some non-typical heating zones,the increased share of E&G for heating was significant and largely driven by income growth,but in typical heating zones,the time-sharing fraction was <5 % and was not significantly increased,except in areas with policy intervention.The intervention policy not only led to dramatic increases in the clean energy fraction for heating but also accelerated the clean cooking transition.Higher income,higher education,younger age,less energy/stove stacking and smaller family size positively impacted the clean energy transition.

关键词： household energy mix energy transition clean heating modern energy sustainable development

The Influence of Islam over the Foreign Policies of Contemporary Islamic Countries

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Asian Journal of Middle Eastern and Islamic Studies 2011年第3期5卷 1-16页

作者： WU yungui Institute for Studies of World Regions Chinese Academy of Social Sciences

Islam is regarded as one of the three major monotheistic religions of the world.It is generally accepted that the so-called“Islamic Countries”usually refer to those countries where Muslims account for a majority of the overall population and Islam exerts a historically profound influence.This article starts its analysis from three aspects:the close connection between Islam and the regimes of states,the dual influence of pan-Islam and Islamic Fundamentalism,and the actual interventions of radical religious organizations.Then the author explores the far-reaching influence of Islam over foreign policies of contemporary Islamic countries.

关键词： Foreign Policies Islam Islamic Countries

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伊斯兰教对当代伊斯兰国家外交政策的影响

世界宗教文化 2010年第3期 1-5页

作者：吴云贵中国社会科学院世界宗教研究所

伊斯兰教是世界三大宗教之一。通常认为,以穆斯林人口为居民主体的国家或历史上受伊斯兰教影响较深的国家即为伊斯兰国家。本文从伊斯兰教与国家政权之间的紧密联系、泛伊斯兰主义与原教旨主义的双重影响以及激进宗教组织的现实干预等... 详细信息

伊斯兰教是世界三大宗教之一。通常认为,以穆斯林人口为居民主体的国家或历史上受伊斯兰教影响较深的国家即为伊斯兰国家。本文从伊斯兰教与国家政权之间的紧密联系、泛伊斯兰主义与原教旨主义的双重影响以及激进宗教组织的现实干预等三个方面切入,深入分析了伊斯兰教对当代伊斯兰国家外交政策的深远影响。

关键词：伊斯兰教伊斯兰国家外交政策

喀斯特山区不同生态条件和栽培密度对杂交水稻产量和品质的影响

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作物研究 2022年第4期36卷 292-299页

作者：冯云贵张建冲覃检潘胜才陈余波秦建权贵州大学农学院贵州贵阳550025

为探索喀斯特山区不同生态条件下杂交水稻高产优质栽培技术,在贵州省贵阳市乌当区新堡乡大寨村和凯里市麻江县杏山镇滥坝村,以不同穗型杂交水稻品种Ⅱ优838(V1)、准两优527(V2)、Y两优900(V3)为材料,设置D1(20 cm×20 cm)、D2(20 cm×30... 详细信息

为探索喀斯特山区不同生态条件下杂交水稻高产优质栽培技术,在贵州省贵阳市乌当区新堡乡大寨村和凯里市麻江县杏山镇滥坝村,以不同穗型杂交水稻品种Ⅱ优838(V1)、准两优527(V2)、Y两优900(V3)为材料,设置D1(20 cm×20 cm)、D2(20 cm×30 cm)2种栽培密度处理,研究生态条件和种植密度对杂交水稻产量和品质的影响。结果表明,3个供试品种的产量均为滥坝村显著高于大寨村(V1品种的D1处理除外),主要原因为每穗粒数和结实率协同增加。糙米率、精米率、长宽比、垩白粒率、垩白度、蛋白质含量均为滥坝村显著高于大寨村,而粒长、粒宽、糊化温度、胶稠度、直链淀粉含量的表现则相反。与D2处理相比,大寨村3个品种D1处理的产量分别显著提高31.59%、8.81%、14.64%,滥坝村则分别显著降低7.96%、19.71%、27.49%,其主要原因是增密种植对2个地区水稻单位面积穗数和每穗粒数影响不同。品质分析结果显示,垩白粒率、垩白度、糊化温度随密度增加而提高,胶稠度和蛋白质含量随密度增加显著降低。综合分析,在低温寡照的大寨村宜密植,通过扩大水稻群体和稳定产量构成因素实现增产,但会增加垩白粒率和垩白度,导致品质下降;在高温高湿的滥坝村则宜稀植,充分发挥个体的生长优势,通过“小群体,壮个体”的途径实现增产和增质的目的,尤其是大穗型水稻品种。

关键词：杂交水稻栽培喀斯特山区生态条件密度产量品质

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医学本科生创新能力培养研究与实践

中华医学教育探索杂志 2016年第5期15卷 520-523页

作者：欧阳琳王云贵黄建军孙鹏潘征柏杨第三军医大学教务处重庆400038 第三军医大学校办重庆400038 第三军医大学训练部重庆400038

通过分析创新能力培养的内涵及现状，列举当前医学生创新能力培养存在的主要问题。以医学本科教育为出发点；从树立创新教育理念，推动“三减、三基、三讲”的教学内容创新，推进以创新为核心的教学方法改革，构建“科教一体”新型师资... 详细信息

通过分析创新能力培养的内涵及现状，列举当前医学生创新能力培养存在的主要问题。以医学本科教育为出发点；从树立创新教育理念，推动“三减、三基、三讲”的教学内容创新，推进以创新为核心的教学方法改革，构建“科教一体”新型师资队伍，完善创新训练体系，加快建设综合化考试体系，建立健全创新教育体制、机制等方面；总结加强医学本科生创新能力培养的经验和做法。

关键词：医学生本科教育创新能力人才培养

云桂客专27.5kV电压互感器高压熔断器频繁熔断原因分析

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电工技术 2022年第2期 57-58,60页

作者：张云峰潘玉忠中国铁路昆明局集团有限公司昆明供电段云南昆明650000

在云桂客专供电系统中,电压互感器经隔离开关、高压熔断器接到27.5 kV母线,供牵引变电所测量及保护使用。当电压互感器故障时,高压熔断器熔断,切除故障电压互感器,保护设备安全。引起高压熔断器熔断的原因多样,主要从设备运行环境、设... 详细信息

在云桂客专供电系统中,电压互感器经隔离开关、高压熔断器接到27.5 kV母线,供牵引变电所测量及保护使用。当电压互感器故障时,高压熔断器熔断,切除故障电压互感器,保护设备安全。引起高压熔断器熔断的原因多样,主要从设备运行环境、设备电气回路电流检测、安装工艺几个方面分析原因,找出高压熔断器熔断的问题根源,制定合理有效的解决方法。

关键词：电气化铁路电压互感器高压熔断器熔断分析

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中国湖泊矿化度的空间分布

海洋与湖沼 2001年第2期32卷 185-191页

作者：潘红玺王苏民中国科学院南京地理与湖泊研究所湖泊沉积与环境开放实验室南京210008

1993年以来 ,对东部平原、云贵高原、蒙新高原等地区主要湖泊采取水样 ,进行了湖水矿化度分析 ,分析方法为容量分析法和火焰分光光度法。结果表明 ,中国湖泊矿化度的空间分布特点 ,大致依纬度及高度可分为青藏高原高矿化湖区、内陆高矿... 详细信息

1993年以来 ,对东部平原、云贵高原、蒙新高原等地区主要湖泊采取水样 ,进行了湖水矿化度分析 ,分析方法为容量分析法和火焰分光光度法。结果表明 ,中国湖泊矿化度的空间分布特点 ,大致依纬度及高度可分为青藏高原高矿化湖区、内陆高矿化湖区、东部低矿化湖区。从东向西存在矿化度逐渐增大的趋势 ,这种明显的区域分异既与自然环境的特点密切相关。

关键词：中国湖泊矿化度空间分布容量分析法分光光度法

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云桂铁路六郎隧道施工通风技术

价值工程 2015年第20期34卷 122-127页

作者：潘红卫中铁十七局集团第四工程有限公司重庆401121

在长大隧道的施工中,施工通风技术对施工的影响很大,针对隧道的具体情况采用不同的施工通风方案是保证隧道通风效果的先决条件,云桂铁路六郎隧道施工通风技术针对六郎隧道三个工区的不同特点,制定了压入式通风、巷道通风及相结合的通风... 详细信息

在长大隧道的施工中,施工通风技术对施工的影响很大,针对隧道的具体情况采用不同的施工通风方案是保证隧道通风效果的先决条件,云桂铁路六郎隧道施工通风技术针对六郎隧道三个工区的不同特点,制定了压入式通风、巷道通风及相结合的通风方式,并在实际应用中取得了良好的通风效果,为同类型的长大隧道通风提供一定的借鉴。

关键词：通风阶段巷道风量计算