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Tomography of the dynamic stress coefficient for stress wave prediction in sedimentary rock layer under the mining additional stress

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International Journal of Mining Science and Technology 2021年第4期31卷 653-663页

作者： Wenlong Shen Guocang Shi yungang wang Jianbiao Bai Ruifeng Zhang Xiangyu wang Henan Key Laboratory for Green and Efficient Mining&Comprehensive Utilization of Mineral Resources School of Energy Science and EngineeringHenan Polytechnic UniversityJiaozuo 454000China Key Laboratory of Deep Coal Resource Mining Ministry of Education State Key Laboratory of Coal Resources and Safe MiningChina University of Mining and TechnologyXuzhou 221116China Collaborative Innovation Center of Coal Work Safety and Clean High Efficiency Utilization Jiaozuo 454000China

In this study,the tomography of dynamic stress coefficient(TDSC)was established based on a mechanical model of stress wave propagation in bedding planes and a mathematical model of the stress wave attenuation in rock *** reliability of the TDSC was verified by a linear bedding plane model and field ***,the TDSC in the dynamic stress propagation of bedding planes increases with the following conditions:(1)the increase of the normal stiffness of the bedding plane,(2)the increase of the incident angle of the stress wave,(3)the decrease of the incident frequency of the stress wave,or(4)the growth of three ratios(the ratios of rock densities,elastic moduli,and the Poisson’s ratios)of rocks on either side of bedding *** additional stress weakens TDSC linearly and slowly during the stress wave propagation in bedding planes,and the weakening effect increases with the growth of the three ***,the TDSC decreases exponentially in the rock mass as propagation distance *** a field case,the TDSC decreases significantly as vertical and horizontal distances increase and its wave range increases as vertical distance increases in the sedimentary rock layers.

关键词： Tomography of the dynamic stress coefficient Stress wave attenuation Mining additional stress Sedimentary rock layer

Using the GPS observations to reconstruct the ionosphere three-dimensionally with an ionospheric data assimilation and analysis system(IDAAS)

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Science China(Technological Sciences) 2014年第11期57卷 2210-2219页

作者： YU Tao MAO Tian wang yungang ZENG ZhongCao wang JingSong FANG HanXian National Center for Space Weather China Meteorological Administration Institute of Geophysics and Geomatics China University of Geosciences College of Meteorological PLA University of Science & Technology

Using an international reference ionosphere(IRI)model as a background ionosphere and applying the Kalman filter to update the state with observations,we develop an ionosphere data assimilation analysis system(IDAAS)to reconstruct a three-dimensional(3D)ionosphere with the GPS slant TEC and ionosonde data over east-south *** preliminary results with the GPS data collected over east-south Asia on 30 June 2005 showed that inversed slant TEC has very good correlation with the observations both for the GPS sites being and not being involved in *** inversed NmF2 and vertical TEC both demonstrate great improvement of agreement with those observed from ionosondes and TOPEX satellite independently.

关键词： ionosphere data assimilation GPS TEC

Study of the ionospheric anomaly before the Wenchuan earthquake

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Chinese Science Bulletin 2009年第4期54卷 1080-1086页

作者： YU Tao MAO Tian wang yungang wang JingSong Nation Center for Space Weather China Meteroligical Administration Beijing 100081 China

The behavior of the ionosphere before the Wenchuan earthquake is analyzed with the global TEC and ionospheric foF2 observed at Xiamen. It can be found from TEC maps that in the afternoon (16―18LT) on May 9, 2008, 3 days before the earthquake, there is an enhancement of TEC with an amplitude of 10―15 TECU appearing in the east-south direction of Wenchuan, and another enhancement appears at the conjugate region of the Southern Hemisphere with an amplitude of 10 TECU, but no obvious in-crement or decrement can be seen in other regions on global scale. It can also be found that on May 6 (6 days before the great earthquake), there is a decrement of TEC with small amplitude of 4TECU and larger area with 80° along the longitude in southern China, and there is no synchronous decrement observed at the conjugate region of the Southern Hemisphere. There are also many anomalies ob-served by ionosondes across China. The result shows that foF2 and TEC abnormally increased, which is different from pervious results that ionospheric parameters decreased prior to earthquakes. Pre-liminary results suggest that the enhancement on May 9 maybe has a close relationship with the pos-sible enhancement of ionospheric electric fields, and it may be an ionospheric precursor of earth-quakes. Whereas the decrement on May 6 may be attributed to the geomagnetic disturbance appearing on May 5.

关键词：电离层异常地震前汶川电离层参数地球电离层地磁场扰动华南地区 TEC

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Exosomes released by granulocytic myeloid-derived suppressor cells attenuate DSS-induced colitis in mice

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Exosomes released by granulocytic myeloid-derived suppressor...

第十届全国免疫学学术大会

作者： yungang wang Shengjun wang

Myeloid-derived suppressor cells(MDSC)have been described in inflammatory bowel disease(IBD),but their role in the disease remains *** this study,we sought to define the role of granulocytic MDSC-derived exosomes(G-MDSC exo)in dextran sulphate sodium(DSS)-induced murine colitis.G-MDSC exo-treated mice showed greater resistance to DSS-induced colitis,as reflected by slower disease activity index,decreased inflammatory cell infiltration,and less colon tissue ***,there are a decrease in the number of Th1 cells and an increase in the number of Tregs in mesenteric lymph nodes from G-MDSC exo-treated colitis ***,lower serum levels of interferon(IFN)-g and tumor necrosis factor(TNF)-αwere detected in G-MDSC exo-treated colitis ***,inhibition of arginase(Arg)-1 activity in G-MDSC exo partially abrogated the spontaneous improvement of *** addition,GMDSC exo could suppress CD4+T cell proliferation and IFN-g secretion in vitro and inhibit the delayed-type hypersensitivity(DTH)response,and these abilities were associated with Arg-1 ***,G-MDSC exo promoted Treg expansion in *** conclusion,G-MDSC exo can attenuate DSS-induced colitis and inflammation,suggesting that they could be a potential therapy for IBD.

关键词： Inflammatory bowel disease Exosomes Myeloid-derived suppressor cells Inflammation

Translation and dissemination strategy of "The Guanzhong School" under the background of "Belt and Road"

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Translation and dissemination strategy of "The Guanzhong Sch...

2019 3rd International Workshop on Arts,Culture,Literature and Language(IWACLL 2019)

作者： wang Cong wang yungang Zhang Jiang Xi'an Fanyi University

The Guanzhong School was founded by Zhang Zai in the Northern Song Dynasty, and it was still popular in the Ming and Qing Dynasties. In the long-term transmission process, the academic views of The Guanzhong School scholars have changed frequently, but their academic spirit generally has its consistent characteristics before and after. Therefore, under the background of "Belt and Road" at the present stage, the author analyzes the translation and dissemination of The Guanzhong School and draws relevant strategies. Studies have shown that The Guanzhong School, as an independent school in the late feudal society of China, not only made outstanding contributions to the theoretical thinking of the Chinese nation in academic thinking, but also formed its own distinctive features in the academic spirit. In addition, in order to build a harmonious society and promote the all-round development of people and society, it is necessary to inherit the excellent spiritual tradition of The Guanzhong School, overcome its limitations and deficiencies, and in the combination with the spirit of the times, transform and renew it and carry it forward. It is also certain that under the new historical conditions, the excellent spirit of The Guanzhong School will be revived and splendid.

关键词： "Belt and Road" "The Guanzhong School" translation and dissemination

IL-17 regulates the antitumor immune response by inhibiting apoptosis of MDSCs in Lewis lung carcinoma bearing mice

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IL-17 regulates the antitumor immune response by inhibiting ...

第十一届全国免疫学学术大会

作者： Juan wang yungang wang Shengjun wang Jiangsu University

Background: Myeloid-derived suppressor cells(MDSCs) weaken the antitumor immune response through the inhibition of effective T cell activity and the production of immunosuppressive factors in pathological sites. It is well established that interleukin-17(IL-17) has a remarkable influence on the promotion of inflammation and tumor formation, and IL-17 has been implicated in the enhancement of immunosuppression of MDSCs, which consequently promotes tumor progression. A detailed study of this relationship remains elusive. The aim of this research was to explore the close effect of IL-17 to MDSCs, and the association with tumor caused by this close ***: Apoptosis of MDSCs was detected by Annexin V/PI assay kit and western blot(WB). The block of ERK1/2 used U0126 which is the inhibitor of ERK1/2. The roles of IL-17 and MDSCs in the tumor were examined by flow cytometry(FCM) and immunofluorescence(IF). Magnetic cell sorting(MACS) was used to isolate MDSCs from spleen in mice. Quantitative real-time PCR(q RT-PCR) was used to confirm the level of i NOS and ***: The apoptosis of MDSCs decreased and ERK1/2 was upregulated with IL-17 treatment in vivo and vitro. After blocking the ERK1/2 of MDSCs, the effect of IL-17 was also blocked in vivo and in vitro. Additionally, IL-17 promotes the development of Lewis lung carcinoma and the percentage of MDSCs was upregulated during this period. In Lewis lung carcinoma models, the level of i NOS and activity of ARG-1 were upregulated with IL-17 treatment confirmed that IL-17 can enhance the suppressive activity of MDSCs. Upon blocking the ERK1/2 of MDSCs in mice, the percentage of Th1 and Tc1 upregulated in different sites discovered that the weakened immune response of tumor mice can restorepartly. Conclusions: IL-17 inhibits apoptosis of MDSCs through ERK1/2. IL-17 promotes tumor growth by inhibiting MDSCs apoposis and enhancing suppressive activity of MDSCs by ERK1/2.

关键词： myeloid-derived suppressor cells interleukin-17 apoptosis tumor immunology

Genetic Diversity Analysis of Wild Tea Plants in Yunnan Province Using EST-SSR Markers

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Agricultural Biotechnology 2015年第1期4卷 9-15页

作者： Meng ZHOU Youyong LI Xuemei SUN Jiajin wang Jin XIE Hao CHENG yungang wang Benying LIU Tea Research Institute Yunnan Academy of Agricultural Sciences Yunnan Technology Engineering Research Center of Tea Germplasm Innovation and Supporting Cultivation Tea Research Institute Chinese Academy of Agricultural Science

In this study, 27 pairs of EST-SSR primers were employed to analyze the genetic diversity and genetic relationship of 100 wild tea plant germplasm re- sources and 22 cultivars, according to the results, a total of 88 polymorphic bands were amplified with 27 pairs of primers; the variation of effective alleles accounted for 69.01% ; a total of 183 genotypes were detected, with a variation range of 4 -11 ; averagely 6.78 genotypes were amplified with each primer pair; Shannon index （I） of 27 primer pairs ranged from 0.32 to I. 35, with an average of 0.88 ; the observed heterozygosity （0.52） was basically consistent with the expected het- erozygosity （0.52） ; the average polymorphism heterozygosity was 0.48, which was very close to 0.50 ; the average Nei＇s index was 0.51, which was higher than 0. 50 ; the average polymorphism information content （PIC） was 0.52, which was higher than 0.50, indicating high genetic diversity among wild tea germplasm resources in Yuunan Province. According to the clustering results, based on geographical origins and genetic backgrounds, 122 materials were clustered into 14 categories. Dendrogram based on Nei＇s genetic distance revealed complex genetic relationships among wild tea germplasm resources in Yunnan Province. This study provided certain reference for subsequent preservation, development and research of wild tea germplasm resources in China.

关键词： Tea plant[ Camellia sinensis (L.) O. Kuntze] EST-SSR Genetic diversity Genetic relationship

A Study of Thermosphere and Mesosphere Wind observed by Fabry-Perot over middle China

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A Study of Thermosphere and Mesosphere Wind observed by Fabr...

2014年中国地球科学联合学术年会——专题29：空间天气与人类活动

作者： Tao Yu Cong Huang Guangxin Zhao Tian Mao yungang wang National Center for Space Weather China Meteorological Administration

A Fabry-Perot interferometer(FPI) system was deployed in Kelan(111.6E, 38.7N), center China in November 2011, which observed the airglows at wavelengths of 892.0 nm, 557.7 nm and 630.0 nm from OH and OI emissions in the upper atmosphere, to derive the wind and temperature at heights around 87 km, 97 km and 250 km, respectively. Since late 2011, except under bad weather conditions or instrument or electric power failure, over 500 nights are suitable to observe the nightglow, and a series of more than 4500 measurements at each height are validated according to manufacture data quality criteria. By using of these data from late 2011 to 2013, the morphology of wind in the mesosphere and thermosphere is investigated in this study. Preliminary results are as follow:(1) at heights of 87 km and 97 km, meridional and zonal winds derived through 892.0 nm and 557.7 nm airglows usually range from-50 m/s to 50 m/s with typical random errors about 60 m/s at 87 km and 2 m/s at 97 km, it suggests an obvious semi-diurnal nighttime variations from April to October but no visible semi-diurnal variation in the rest month. The monthly mean winds are in good agreement with that of HWM93 results(2) At height of 250 km, meridional and zonal winds derived through 630.0 nm nightglow range from 80 m/s to-110 m/s with typical random errors about 80 m/s, and they are also good consistent with HWM93 results.(3) At the heights of 87 km and 97 km, meridional winds have a visible annual variation at 12- 17 UT and with a little semi-annual variation in the rest time, but the zonal winds have a semi-annual variation all the night time, as for the height of 250 km, seasonal dependence of the winds is generally annual, but there are isolated cases in which a semiannual variation is observed.(4) The horizontal winds at 250 km have an evident response to two the storms happened at July 2012, which seem to be an enhancement of velocity in the southwestward wind. But no obvious storm effects can be found d

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盾构隧道施工轴线纠偏计算方法

城市轨道交通研究 2017年第1期20卷 75-78页

作者：王运钢徐岩军中铁一局集团有限公司西安工程师710054 中铁一局集团城市轨道交通工程有限公司西安710054

地铁隧道采用盾构法施工时,受到各种因素的影响,盾构机及隧道衬砌环的轴线会偏离设计轴线。此偏差甚至会超出允许范围,从而引起隧道施工以及运行的安全隐患。针对此问题,总结了产生轴线偏差的各个影响因子,并提出了一种有效的纠偏方法... 详细信息

地铁隧道采用盾构法施工时,受到各种因素的影响,盾构机及隧道衬砌环的轴线会偏离设计轴线。此偏差甚至会超出允许范围,从而引起隧道施工以及运行的安全隐患。针对此问题,总结了产生轴线偏差的各个影响因子,并提出了一种有效的纠偏方法。阐述了该纠偏技术的原理和实施方法。

关键词：地铁盾构隧道轴线偏差纠偏方法