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What Controls the Distribution of Ore Veins in Quartz Vein-type Tungsten Deposits: Constrains from Fan-shaped Mineralization in SE China

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Journal of Earth Science 2024年

作者： Gui-Cong Fang Deng-Hong Wang fu-Qiang Yang Zhan-Xu Ni chang-Shuai Huang Ping Wang Meng Feng Zuo-Hai Feng Guangxi Key Laboratory of Hidden Metallic Ore Deposits Exploration， College of Earth Science， Guilin University of Technology Collaborative Innovation Center for Exploration of Nonferrous Metal Deposits and Efficient Utilization of Resources By the Province and Ministry，Guilin University of Technology Institute of Mineral Resources， Chinese Academy of Geological Sciences Guangxi Zhuang Autonomous Region Institute of Geophysical Exploration Geological Team No.271 of Guangxi Zhuang Autonomous Region China Nonferrous Metal Guilin Research Institute of Geology for Mineral Resources Co.， Ltd Guangdong Geologic Survey Institute

Quartz vein-type tungsten deposits are a common W deposit type. Their ore vein distribution was previously considered to be controlled by regional horizontal tectonic stress. In this paper， 14 tungsten deposits with fan-shaped mineralization in SE China are summarized， and the relations between their ore veins and granite and the ore-forming structural stress field are analyzed. These deposits have a post-magmatic hydrothermal genesis and involve the formation of two sets of veins with similar strike and opposite dips at the top of the ore-causative granite bodies， forming a vertical fan-shaped profile. Their ore veins were coeval with the underlying granite bodies， and generally extend along the long axis of the granite. In such fan-shaped ore formation， the stress is highly focused at the top of the granite and gradually weakens outward. The maximum principal stress (σ1) is perpendicular to the granite contact surface， and radiates outward from the pluton. Meanwhile， the minimum principal stress (σ3) forms an arc-shaped band parallel to the contact surface. Our findings， together with published numerical modeling indicate that the emplacement dynamics of granitic magma (rather than regional horizontal tectonic stress) are essential controls on the distribution of ore veins in quartz vein-type tungsten deposits.

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International standard of Traditional Chinese Medicine Techniques: Traditional Chinese Medicine guidelines for acute primary headache(2022)

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Journal of Traditional Chinese Medicine 2024年第4期44卷 839-850页

作者： YAO Yuning CAO Kegang ZHANG Genming LIU Jianping CHEN Wei CAO Junling YANG Wenming YAN Yongmei GENG chang JU Yi ZHAO Dexi QU Miao LI Xiaoli SUN Li HAN Zhenyun HE Liyun CUI Fangyuan fu Caihong ZHOU Bo LIAO Shuqin Department of Neurology Dongzhimen Hospital of Beijing University of Chinese MedicineBeijing 100007China Centre for Evidence-Based Chinese Medicine Beijing University of Chinese MedicineBeijing 100029Chin Encephalopathy center First Affiliated Hospital of Anhui University of Chinese MedicineHefei 230031China Department of Neurology Affiliated Hospital of Shaanxi University of Chinese MedicineXi'an 710077China Department of Neurology Beijing Changping District Hospital of Traditional Chinese MedicineBeijing 102299China Neurology center Beijing Tiantan HospitalCapital Medical UniversityBeijing 100050China Department of Neurology Affiliated Hospital of Changchun University of Chinese MedicineChangchun 130021China Department of Neurology Xuanwu HospitalCapital Medical UniversityBeijing 100053Chin Department of Neurology Beijing University of Chinese Medicine Third Affiliated HospitalBeijing 100029China Department of Geriatrics Jilin Academy of Traditional Chinese MedicineChangchun 130012China Department of Neurology Shenzhen Hospital of Beijing University of Chinese MedicineShenzhen 518172China Institute of Basic Research in Clinical Medicine China Academy Of Chinese Medical SciencesBeijing 100700Chin Department of Rehabilitation Shunyi HospitalBeijing Traditional Chinese Medicine HospitalBeijng 101300China Department of Neurology Xiyuan Hospital of China Academy of Chinese Medical SciencesBeijing 100091China

OBJECTIVE:To summarize the evidence from Traditional Chinese Medicine(TCM)practice in the treatment of acute primary headache and provide clinical practice ***:The guidelines were developed in accordance with the World Health Organization guideline development *** the establishment of steering committee,panel and the registration and protocol formulation,the evidence on TCM for acute primary headache from published guidelines,clinical evidence,and expert experience and consensus were *** grading of recommendations assessment,development and evaluation method was used to grade the evidence and make the ***:Based on the available evidence,the guidelines recommended three TCM herbal decoctions,six Chinese patent medicines,and two kinds of external application of Chinese herbal *** recommendations based on the expert experience and consensus were also included in the ***:TCM diagnosis and treatment of decoction,Chinese patent medicine and external application for treating acute primary headache were *** hope these guidelines will be helpful in standardize the TCM acute treatment of primary headache.

关键词： medicine,Chinese traditional acute primary headache practice guideline

透射式GaAs光电阴极性能提高以及结构优化

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物理学报 2024年第3期73卷 266-272页

作者：吕行富容国常本康郭欣王芝南京理工大学电子工程与光电技术学院南京210094 昆明物理研究所昆明650221 西安应用光学研究所西安710065

为了提高透射式GaAs光电阴极性能,将国内与美国ITT公司的透射式GaAs光电阴极量子效率曲线进行对比,可知我国透射式光电阴极积分灵敏度已经达到2130μA/lm,美国ITT达到了2330μA/lm.利用修正后的量子效率、光学性能以及积分灵敏度的理论... 详细信息

为了提高透射式GaAs光电阴极性能,将国内与美国ITT公司的透射式GaAs光电阴极量子效率曲线进行对比,可知我国透射式光电阴极积分灵敏度已经达到2130μA/lm,美国ITT达到了2330μA/lm.利用修正后的量子效率、光学性能以及积分灵敏度的理论模型,分别对两者进行光学结构拟合.结果表明,国内光电阴极在窗口层和发射层的厚度、电子扩散长度以及后界面复合速率等方面均与ITT有一定差距.为了缩短两者的差距,优化阴极结构参数,具体研究了电子扩散长度和发射层厚度对量子效率的影响,结果表明如果均匀掺杂透射式GaAs光电阴极发射层厚度为1.3μm、电子扩散长度为7μm,则积分灵敏度可以达到2800μA/lm以上.

关键词： Ga As光电阴极透射式结构优化光学性能光电发射性能

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Single-cell immune landscape of measurable residual disease in acute myeloid leukemia

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Science China Life Sciences 2024年

作者： Xiaodong Mo Weilong Zhang Guomei fu Yingjun chang Xiaohui Zhang Lanping Xu Yu Wang Chenhua Yan Mengzhu Shen Qiuxia Wei changjian Yan Xiaojun Huang Peking University People's Hospital Peking University Institute of Hematology National Clinical Research Center for Hematologic Disease Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation Department of Hematology Lymphoma Research Center Peking University Third Hospital Peking-Tsinghua Center for Life Sciences Academy for Advanced Interdisciplinary Studies Peking University Research Unit of Key Technique for Diagnosis and Treatments of Hematologic Malignancies Chinese Academy of Medical Sciences

Measurable residual disease(MRD) is a powerful prognostic factor of relapse in acute myeloid leukemia(AML). We applied the single-cell RNA sequencing to bone marrow(BM) samples from patients with(n=20) and without(n=12) MRD after allogeneic hematopoietic stem cell transplantation. A comprehensive immune landscape with 184,231 cells was created. Compared with CD8+T cells enriched in the MRDnegative group(MRD-＿CD8), those enriched in the MRD-positive group(MRD+＿CD8) showed lower expression levels of cytotoxicity-related genes. Three monocyte clusters(i.e., MRD+＿M) and three B-cell clusters(i.e., MRD+＿B) were enriched in the MRD-positive group. Conversion from an MRD-positive state to an MRD-negative state was accompanied by an increase in MRD-＿CD8 clusters and vice versa. MRDenriched cell clusters employed the macrophage migration inhibitory factor pathway to regulate MRD-＿CD8 clusters. These findings revealed the characteristics of the immune cell landscape in MRD positivity, which will allow for a better understanding of the immune mechanisms for MRD conversion.

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赋存环境对含甲烷水合物沉积物力学特性的影响

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岩土力学 2024年第7期45卷 1987-1999页

作者：冯帅陈盼周家作韦昌富中国科学院武汉岩土力学研究所岩土力学与工程国家重点实验室湖北武汉430071 中国科学院大学北京100049 中国地质大学海洋学院湖北武汉430074

海域水合物沉积物储层的强度与刚度特性对水合物的安全高效钻采有重要意义。为研究赋存环境变化对泥质水合物沉积物抗剪强度特性的影响,基于改进的水合物三轴剪切仪开展了一系列饱水与饱气及地应力条件变化下甲烷水合物沉积物的排水剪... 详细信息

海域水合物沉积物储层的强度与刚度特性对水合物的安全高效钻采有重要意义。为研究赋存环境变化对泥质水合物沉积物抗剪强度特性的影响,基于改进的水合物三轴剪切仪开展了一系列饱水与饱气及地应力条件变化下甲烷水合物沉积物的排水剪切试验。试验结果表明,赋存环境变化对泥质水合物的抗剪强度与刚度产生显著影响。饱水条件下相同水合物饱和度沉积物抗剪强度显著降低,抗剪强度最大降低率达52.0%。赋存环境变化对内摩擦角影响有限,对黏聚力影响显著。与饱气条件下的结果相比,饱水条件下有效黏聚力最大降低率达68.1%,进一步确定了有效黏聚力随水合物饱和度演化的指数方程。水饱和下水合物沉积物的变形模量显著降低,变形模量E_(50)的最大降低比达72.7%;水饱和条件下,变形模量随水合物饱和度的增大呈线性增长。基于气饱和与水饱和条件下水合物沉积物骨架的受力分析,初步揭示了两种赋存环境下水合物沉积物力学特性的演化机制。研究成果可为天然气水合物赋存机制揭示及储层稳定性评价提供基础数据与方法支持。

关键词：甲烷水合物泥质粉砂水饱和抗剪强度变形模量

基于SWMM的车库顶板虹吸排水收集系统排水性能模拟

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水电能源科学 2024年第3期42卷 128-132页

作者：宋长甫中铁二十局集团房地产开发有限公司重庆401336

为探究车库顶板虹吸排水收集系统的排水性能,以重庆市某住宅小区车库顶板虹吸排水项目为例,提出了一种基于暴雨洪水管理模型(SWMM)的车库顶板虹吸排水模拟方法,结合径流系数法和现场实测数据对模型的可靠性和准确性进行了验证,并模拟分... 详细信息

为探究车库顶板虹吸排水收集系统的排水性能,以重庆市某住宅小区车库顶板虹吸排水项目为例,提出了一种基于暴雨洪水管理模型(SWMM)的车库顶板虹吸排水模拟方法,结合径流系数法和现场实测数据对模型的可靠性和准确性进行了验证,并模拟分析了研究区的虹吸排水收集系统在不同设计重现期下的下渗与排水过程。结果表明,模型可较好地反映研究区虹吸系统的水力特性与排水能力,且在5年一遇设计重现期下虹吸排水管可较好地实现虹吸状态的启动,并有效排除车库顶板排水层内的滞水而未产生明显积水现象。但其排水槽尺寸设计存在充满度过低的问题,而采用逐渐增大排水槽尺寸的优化设计可显著增加充满度,提升排水利用率。

关键词：虹吸排水车库顶板数值模拟 SWMM 排水槽尺寸

Prospect of ultrahigh-resolution fast neutron absorption spectroscopy based on a laser plasma electron accelerator

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High Power Laser Science and Engineering 2024年第1期12卷 108-115页

作者： Wen-Zhao Wang Jie Feng Xiao-Peng Zhang Yao-Jun Li Wei-Jun Zhou Wen-Chao Yan Guo-Qiang Zhang chang-Bo fu Li-Ming Chen Key Laboratory of Laser Plasma(MoE) School of Physics and AstronomyShanghai Jiao Tong UniversityShanghaiChina IFSA Collaborative Innovation Center Shanghai Jiao Tong UniversityShanghaiChina Institute of High Energy Physics Chinese Academy of SciencesBeijingChina Shanghai Advanced Research Institute Chinese Academy of SciencesShanghaiChina Key Laboratory of Nuclear Physics and Ion-beam Application(MoE) Institute of Modern PhysicsFudan UniversityShanghaiChina

Fast neutron absorption spectroscopy is widely used in the study of nuclear structure and element analysis. However,due to the traditional neutron source pulse duration being of the order of nanoseconds, it is difficult to obtain a high-resolution absorption spectrum. Thus, we present a method of ultrahigh energy-resolution absorption spectroscopy via a high repetition rate, picosecond duration pulsed neutron source driven by a terawatt laser. The technology of single neutron count is used, which results in easily distinguishing the width of approximately 20 keV at 2 MeV and an asymmetric shape of the neutron absorption peak. The absorption spectroscopy based on a laser neutron source has one order of magnitude higher energy-resolution power than the state-of-the-art traditional neutron sources, which could be of benefit for precisely measuring nuclear structure data.

关键词： fast neutron absorption spectroscopy laser plasma accelerator photo-nuclear neutrons single neutron count

Intergeneric chromosome-specific painting reveals differential chromosomal transmission from Tripidium arundinaceum in sugarcane progeny

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Journal of Integrative Agriculture 2024年第11期23卷 3751-3762页

作者： Fan Yu Zehuai Yu Jin Chai Xikai Yu Chen fu Xinwang Zhao Hailong chang Jiawei Lei Baoshan Chen Wei Yao Muqing Zhang Jiayun Wu Qinnan Wang Zuhu Deng State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources/Guangxi Key Laboratory for Sugarcane Biology College of Agriculture Guangxi University National Engineering Research Center for Sugarcane Fujian Agriculture and Forestry University Institute of Nanfan & Seed Industry Guangdong Academy of Sciences Key Laboratory of Sugarcane Biology and Genetic Breeding Ministry of Agriculture and Rural Affairs/Fujian Agriculture and Forestry University

Sugarcane has recently attracted increasing attention for its potential as a source of sugar and bioethanol, so increasing its yield is essential to ensure the sugar security and bioenergy production. Intergeneric hybridization is a highly efficient method to produce new genetic variants of crop plants, particularly those species with high ploidy such as sugarcane(Saccharum spp.). Tripidium arundinaceum exhibits many desirable agronomic traits, and has been widely studied to produce hybrids with improved stress tolerance and other characteristics in sugarcane breeding. However, the genetic relationship between T. arundinaceum and Saccharum species, and the individual T. arundinaceum chromosomal compositions in sugarcane hybrids are still elusive. Here we used whole-genome single-nucleotide polymorphisms(SNPs) to ascertain the phylogenetic relationships between these species and found that T. arundinaceum is more closely related to Saccharum than Sorghum, in contrast to the previous narrow genetic analyses using chloroplast DNA. Additionally, oligonucleotide(oligo)-based chromosome-specific painting derived from Saccharum officinarum was able to distinctly identify the chromosomes of T. arundinaceum. We developed the oligo-genomic in situ hybridization(GISH) system for the first time, to unveil the novel chromosome translocations and the transmission of individual T. arundinaceum chromosomes in sugarcane progeny. Notably,we discovered that the chromosomal transmission of T. arundinaceum exhibited several different inheritance modes,including n, 2n, and over 2n in the BC1 progenies. Such inheritance patterns may have resulted from first division restitution(FDR) or FDR+nondisjunction of a chromosome with the sister chromatids in the second meiosis division/second division restitution(FDR+NSC/SDR) model during meiosis. These results will be of substantial benefit for the further selection of T. arundinaceum chromosomes for sugarcane genetic improvement.

关键词： sugarcane Tripidium arundinaceum chromosome painting Oligo-FISH chromosomal transmission

Hepatic TRPC3 loss contributes to chronic alcohol consumption-induced hepatic steatosis and liver injury in mice

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Life Metabolism 2024年第1期3卷 51-66页

作者： Qinchao Ding Rui Guo Liuyi Hao Qing Song Ai fu Shanglei Lai Tiantian Xu Hui Zhuge Kaixin chang Yanli Chen Haibin Wei Daxi Ren Zhaoli Sun Zhenyuan Song Xiaobing Dou Songtao Li School of Public Health Zhejiang Chinese Medical UniversityHangzhouZhejiang 310053China College of Animal Science Zhejiang UniversityHangzhouZhejiang 310058China Department of Kinesiology and Nutrition University of Illinois at ChicagoChicagoIL 60612United States School of Life Science Zhejiang Chinese Medical UniversityHangzhouZhejiang 310053China Department of Surgery Johns Hopkins University School of MedicineBaltimoreMD 21205United States

Emerging evidence discloses the involvement of calcium channel protein in the pathological process of liver *** receptor potential cation channel subfamily C member 3(TRPC3),a ubiquitously expressed non-selective cation channel protein,controls proliferation,inflammation,and immune response via operating calcium influx in various ***,our understanding on the biofunction of hepatic TRPC3 is still *** present study aims to clarify the role and potential mechanism(s)of TRPC3 in alcohol-associated liver disease(ALD).We recently found that TRPC3 expression plays an important role in the disease process of *** exposure led to a significant reduction of hepatic TRPC3 in patients with alcohol-related hepatitis(AH)and ALD ***(N-acetylcysteine and mitoquinone)intervention improved alcohol-induced suppression of TRPC3 via a miR-339-5p-involved ***3 loss robustly aggravated the alcohol-induced hepatic steatosis and liver injury in mouse liver;this was associated with the suppression of Ca^(2+)/calmodulin-dependent protein kinase kinase 2(CAMKK2)/AMP-activated protein kinase(AMPK)and dysregulation of genes related to lipid ***3 loss also enhanced hepatic inflammation and early fibrosis-like change in *** hepatic TRPC3 effectively reversed chronic alcohol-induced detrimental alterations in ALD ***,chronic alcohol exposure-induced TRPC3 reduction contributes to the pathological development of ALD via suppression of the CAMKK2/AMPK *** stress-stimulated miR-339-5p upregulation contributes to alcohol-reduced ***3 is the requisite and a potential target to defend alcohol consumption-caused ALD.

关键词： TRPC3 alcohol-associated liver disease miR-339-5p hepatic steatosis liver injury CAMKK2/AMPK