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The Toxic Effects of Strong Chlorin Disinfectant on Mangroves and Emission Thresholds

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Open Journal of Ecology 2024年第2期14卷 114-124页

作者： yunan yang Nan Zhou Xinyu Liu School of Space and Environment Beihang University Beijing China

In this study, based on the simulated discharge results of chemical disinfectants, hypocotyl germination concentration gradient pre-test and concentration gradient determination experiment were set up respectively. Laboratory cultivation was conducted to compare and analyze the root germination and germination indexes, three mangrove hypocotyls of Kandelia candel (Linn.) Druce, Ceriopstagal C.B. Rob. and Bruguiera sexangula var. Rhynchopetalas’ efficiency of cumulative root germination, cumulative germination and the cumulative expansion of the second pair of leaves, one-way analysis of variance was used to obtain the tolerance threshold of three mangrove hypocotyls to strong chlorin disinfectant. The study determined that the by-products of strong chlorin disinfectant, the toxic threshold concentrations of Kandelia candel (Linn.) Druce, Ceriopstagal C.B. Rob. and Bruguiera sexangula var. rhynchopetala are close to 0.55 mg/L, 0.55 mg/L and 0.25 mg/L, respectively. This concentration range is lower than the average concentration of 1.183 mg/L of active chlorine emitted from strong chlorine concentrate during pond clearing in high-level shrimp ponds, indicating that transient emissions of strong chlorine concentrate during pond clearing can have a toxic effect on mangrove plants. The strength of tolerance of the embryonic axes of the three mangrove species to effective chlorine contamination was, Ceriopstagal C.B. Rob. stronger than Bruguiera sexangula var. rhynchopetala, and Kandelia candel (Linn.) Druce is the weakest.

关键词： Strong Chlorin Toxicity Threshold Germination of Mangrove Hypocotyls One-Way Analysis of Variance

Review on Possible Factors for Outbreak of Wood Boring Isopod, Sphaeroma spp. Which Causes Destructive Impact on Mangrove Forest in China

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Open Journal of Ecology 2022年第3期12卷 211-235页

作者： Myat Thiri yunan yang School of Space and Environment Beihang University Beijing China Biotechnology Research Department Ministry of Education Naypyidaw Myanmar

The tropical and subtropical mangrove biomes form the foundation of a highly productive and biologically rich ecosystem providing essential goods and services to human beings. Despite its values, the stability and survival of mangroves are consistently threatened by anthropogenic activities and their associated degradation, resulting in their disappearance. After realizing their ecological importance, in recent years, rehabilitation and restoration programs for mangrove forests have been launched globally. Unfortunately, most mangrove restoration efforts yielded negative results and failed to re-establish mangrove forests because of technical and social failures. Besides, the continued outbreak of wood borer, Sphaeroma spp., in mangrove forests has become one of the destructive causes of natural and restored mangrove forests in some nations including China. However, few studies on the biology of Sphaeroma spp. found in Chinese mangrove ecosystem have been done, and little is known concerning the factors affecting their outbreak in China. In this review, we discussed the possible factors that affect the rapid growth and recruitment of Sphaeroma spp. in the mangrove ecosystem by examining the information of the wood borer Sphaeroma spp. from the scattered pieces of literature with great regard. We discussed the relationship between the recruitment of Sphaeroma spp. and the tide and flow of water, food availability from the surrounding water and water quality including salinity, temperature, and the pollution of water. In addition to these factors, the reduced biodiversity of restored mangrove forest could be one of the main reasons for the outbreak of isopod. We also discussed the destructive impact of the isopod’s outbreak and the possible ways to control their outbreak in mangrove forest.

关键词： Isopod’s Outbreak Sphaeroma Species Destructive Impact Mangrove Forest Restoration

Bio-soft matter derived from traditional Chinese medicine:Characterizations of hierarchical structure,assembly mechanism,and beyond

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Journal of Pharmaceutical Analysis 2024年第6期14卷 823-839页

作者： Guiya yang Yue Liu Yuying Hu Yue Yuan yunan Qin Quan Li Shuangcheng Ma School of Traditional Chinese Medicine Beijing University of Chinese MedicineBeijing102488China Institute for Control of Chinese Traditional Medicine and Ethnic Medicine National Institutes for Food and Drug ControlBeijing100050China Tianjin Key Laboratory of Therapeutic Substance of Traditional Chinese Medicine School of Chinese Materia MedicaTianjin University of Traditional Chinese MedicineTianjin301617China Collaborative Innovation Center for Advanced Organic Chemical Materials Co-constructed by the Province and Ministry Ministry-of-Education Key Laboratory for the Synthesis and Application of Organic Functional MoleculesCollege of Chemistry and Chemical EngineeringHubei UniversityWuhan430062China

Structural and functional explorations on bio-soft matter such as micelles,vesicles,nanoparticles,aggregates or polymers derived from traditional Chinese medicine(TCM)has emerged as a new topic in the field of *** discovery of such cross-scaled bio-soft matter may provide a unique perspective for unraveling the new effective material basis of TCM as well as developing innovative medicine and *** the rapid rise of TCM-derived bio-soft matter,their hierarchical structure and assembly mechanism must be unambiguously probed for a further in-depth understanding of their pharmacological *** this review,the current emerged TCM-derived bio-soft matter assembled from either small molecules or macromolecules is introduced,and particularly the unambiguous elucidation of their hierarchical structure and assembly mechanism with combined electron microscopic and spectroscopic techniques is *** pros and cons of each technique are also *** future challenges and perspective of TCM-derived bio-soft matter are outlined,particularly the requirement for their precise in situ structural determination is highlighted.

关键词： Electron microscopy Spectroscopy Traditional Chinese medicine Bio-soft matter Structural characterization

The role of m^(6)A RNA methylation in autoimmune diseases: Novel therapeutic opportunities

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Genes & Diseases 2024年第1期11卷 252-267页

作者： yunan Shan Wei Chen Yanbin Li The First Clinical Medical College Shandong University of Traditional Chinese MedicineJinanShandong 250013China Department of Neurology The First Affiliated Hospital of Shandong First Medical University&Shandong Provincial Qjanfoshan HospitalShandong Institute of NeuroimmunologyShandong Key Laboratory of Rheumatic Disease and Translational MedicineJinanShandong 250013China Department of Gastroenterology Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai 200233China

N6-methyladenosine m^(6)A modifications,as one of the most common forms of in-ternal RNA chemical modifications in eukaryotic cells,have gained increasing attention in recent *** m^(6)A RNA modifications exert various crucial roles in various biological pro-cesses,such as embryonic development,neurogenesis,circadian rhythms,and *** advances have highlighted that m^(6)A RNA modification plays an important role in im-mune response,especially in the initiation and progression of autoimmune *** this re-view,we summarized the regulatory mechanisms of m^(6)A methylation and its biological functions in the immune system and mainly focused on recent progress in research on the po-tential role of m^(6)A RNA methylation in the pathogenesis of autoimmune diseases,thus providing possible biomarkers and potential targets for the prevention and treatment of auto-immunediseases.

关键词： Adaptive immunity Autoimmune diseases Innate immunity Immune response m^(6)A RNA methylation

Risk Assessment of Multi-Hazards in Hangzhou: A Socioeconomic and Risk Mapping Approach Using the CatBoost-SHAP Model

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INTERNATIONAL JOURNAL OF DISASTER RISK SCIENCE 2024年第4期15卷 640-656页

作者： Yu, Bofan Yan, Jiaxing Li, yunan Xing, Huaixue China Univ Geosci Wuhan Inst Geol Survey Wuhan 430074 Peoples R China China Geol Survey Nanjing Ctr Nanjing 210016 Peoples R China

As the global push for sustainable urban development progresses, this study, set against the backdrop of Hangzhou City, one of China's megacities, addressed the conflict between urban expansion and the occurrence of urban geological hazards. Focusing on the predominant geological hazards troubling Hangzhou-urban road collapse, land subsidence, and karst collapse-we introduced a Categorical Boosting-SHapley Additive exPlanations (CatBoost-SHAP) model. This model not only demonstrates strong performance in predicting the selected typical urban hazards, with area under the curve (AUC) values reaching 0.92, 0.92, and 0.94, respectively, but also, through the incorporation of the explainable model SHAP, visually presents the prediction process, the interrelations between evaluation factors, and the weight of each factor. Additionally, the study undertook a multi-hazard evaluation, producing a susceptibility zoning map for multiple hazards, while performing tailored analysis by integrating economic and population density factors of Hangzhou. This research enables urban decision makers to transcend the "black box" limitations of machine learning, facilitating informed decision making through strategic resource allocation and scheduling based on economic and demographic factors of the study area. This approach holds the potential to offer valuable insights for the sustainable development of cities worldwide.

关键词： Hangzhou city Multi-hazard risk assessment Machine learning Machine learning interpretability Socioeconomic analysis Urban sustainability development SUSTAINABLE URBAN-DEVELOPMENT SOCIAL VULNERABILITY SUBSIDENCE CHINA

Large eddy simulation study on drag reduction performance of array-based plasma synthetic jet actuators

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Chinese Journal of Aeronautics 2024年第10期37卷 118-135页

作者： yunan WANG Zhenbing LUO Wei XIE Yan ZHOU Qiang LIU Wenqiang PENG Yinxin ZHU College of Aerospace Science and Engineering National University of Defense TechnologyChangsha 410073China

Large Eddy Simulation(LES)is first used to investigate the drag reduction effect of an array-based configuration of Plasma Synthetic Jet Actuators(PSJAs)on a hemisphere in supersonic inflow,and analyze the effect of energy allocation and array angle on the drag reduction performance of opposing Plasma Synthetic Jet(PSJ)in this *** simulation results have been compared with experimental data,confirming the validity of the simulation *** results show that different energy allocations have a significant effect on the drag of the ***,the effect of the change in array angle on the drag of the hemisphere is not as noticeable as the effect caused by energy *** regions between the two PSJAs occur,which undermine the effectiveness of drag *** Turbulent Kinetic Energy(TKE)regions primarily concentrate on the core region of the jet and downstream of the bow *** influence of the array angle on TKE is most evident in the downstream region of the exits of the PSJs on both *** evolution of the coherent structures reveals that as the PSJ intensity decreases,the largescale vortices progressively break up into smaller-scale vortices,and energy is also transferred from large-scale structures to small-scale structures.

关键词： Plasma synthetic jet Shock wave Large eddy simulation Drag reduction Flow control

Constructing thermoresponsive PNIPAM-based microcarriers for cell culture and enzyme-free cell harvesting

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Chinese Chemical Letters 2024年第7期35卷 412-416页

作者： yunan Yuan Zhimin Luo Jie Chen Chaoliang He Kai Hao Huayu Tian CAS Key Laboratory of Polymer Ecomaterials Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun 130022China School of Applied Chemistry and Engineering University of Science and Technology of ChinaHefei 230026China College of Chemistry and Chemical Engineering Xiamen UniversityXiamen 361005China Jilin Biomedical Polymers Engineering Laboratory Changchun 130022China Innovation Laboratory for Sciences and Technologies of Energy Materials of Fujian Province(IKKEM) Xiamen 361005China

The development of large-scale cell cultivation and non-invasive cell harvesting is highly desired in various fields,including biological regeneration and pharmaceutical *** using traditional microcarriers for cell culture,trypsinization is often necessary during cell collection,leading to partial cells *** this work,we developed a thermoresponsive glass microcarrier modified with poly(γ-propargyl-L-glutamate)(PPLG)and poly(N-isopropylacrylamide)(PNIPAM).We utilized these microcarriers for three-dimensional cell culture and enzyme-free cell harvesting,and the results indicated that the prepared microcarriers exhibited excellent non-invasive cell culture performance.

关键词： Microcarrier Temperature-responese PNIPAM Polymers Cell culture

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循环经济理念下应急管理人力资源配置研究

前沿 2010年第17期 174-177页

作者：杨渝南四川循环经济研究中心西南科技大学经济与管理学院四川绵阳621010

在突发公共事件的发生高频率和广泛影响的前提下,应急管理成为目前公共管理的热点问题。仅依靠政府的力量很难以形成快速、高效、协调的应急管理机制。本文以国家发展循环经济为契机,从组织属性和环境研究的角度,提出对应急管理人力资... 详细信息

在突发公共事件的发生高频率和广泛影响的前提下,应急管理成为目前公共管理的热点问题。仅依靠政府的力量很难以形成快速、高效、协调的应急管理机制。本文以国家发展循环经济为契机,从组织属性和环境研究的角度,提出对应急管理人力资源进行战略配置的若干建议。

关键词：循环经济应急管理人力资源配置

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三角波作用下峰前峰后砂岩力学响应试验研究

华中科技大学学报（自然科学版） 2018年第9期46卷 119-126页

作者：刘杰付玲莉杨渝南王飞三峡大学三峡库区地质灾害教育部重点实验室湖北宜昌443002 三峡大学土木与建筑学院湖北宜昌443002

对同一砂岩,在相同围压、荷载峰值及应力水平、不同位移速率控制条件下,进行了三角波峰前峰后加卸载实验,选取峰前峰后45 MPa应力区间两个循环加载段进行对比分析,得出表观弹性模量与轴向变形存在线性关系;推导得出三角波位移/围压控制... 详细信息

对同一砂岩,在相同围压、荷载峰值及应力水平、不同位移速率控制条件下,进行了三角波峰前峰后加卸载实验,选取峰前峰后45 MPa应力区间两个循环加载段进行对比分析,得出表观弹性模量与轴向变形存在线性关系;推导得出三角波位移/围压控制荷载作用下的加载速率预测公式与i时刻的能量预测公式,峰前峰后加载速率与能量的预测计算结果与实测结果较为相符,验证了该线性关系的工程及理论推导应用价值;定义了力加载的加速度和位移速度的放大倍数分别为K和V,得出位移速率的增加对力加载的加速度的增加具有线性增速效应,其中K/V峰前最大可达28倍,K/V峰后最大可达22倍,在工程实践中依此规律,由易测的位移速率预测力加载的加速度;加载段峰前增速效应比峰后大,卸载段峰前与峰后的增速效应相近;在相同的加载条件下峰后的滞后时间比峰前长;峰后加载全过程岩样所吸收的能量要大于峰前加载全过程岩样所吸收的能量,峰后岩石吸收峰值能量约是峰前的1.5倍,峰后岩石加卸载循环后内能约是峰前的2倍.

关键词：砂岩力学峰前峰后循环加载三角波表观弹性模量能量发育滞回圈