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抗苗勒氏管激素在妇产科领域的研究进展

生殖与避孕 2014年第8期34卷 668-671页

作者：米东张云山天津市中心妇产科医院天津300100

抗苗勒氏管激素(AMH)属于转化生长因子β超家族,在调节生殖细胞发育和分化中发挥重要作用,本文阐述了AMH与卵巢功能、多囊卵巢综合征(PCOS)、辅助生殖以及肿瘤的关系。研究显示血清AMH水平可以准确反映卵巢储备能力,在辅助生殖中具有重... 详细信息

抗苗勒氏管激素(AMH)属于转化生长因子β超家族,在调节生殖细胞发育和分化中发挥重要作用,本文阐述了AMH与卵巢功能、多囊卵巢综合征(PCOS)、辅助生殖以及肿瘤的关系。研究显示血清AMH水平可以准确反映卵巢储备能力,在辅助生殖中具有重要应用价值,AMH还可以作为诊断多PCOS的指标。近年来越来越多的研究表明血清AMH升高是卵巢癌等肿瘤的标志物,且AMH对卵巢癌等肿瘤的生长、迁移和侵袭有抑制作用,可能成为肿瘤治疗的新药物。AMH在妇产科领域具有广阔的的应用前景。

关键词：抗苗勒氏管激素(AMH) 卵巢功能多囊卵巢综合征(PCOS) 辅助生殖肿瘤

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胚胎反复植入失败的母体因素及应对策略

生殖与避孕 2014年第2期34卷 143-148,166页

作者：张伟伟张云山天津医科大学天津300070 天津市中心妇产科医院生殖医学中心天津300100

胚胎反复植入失败(repeated implantation failure,RIF)是在经过多次IVF-ET后,移植的胚胎没有着床。胚胎植入失败与母体或胚胎因素有关,其中母体因素包括宫腔病理学、血栓形成倾向和免疫因素等。近年来许多方法用于改善和治疗引起RIF的... 详细信息

胚胎反复植入失败(repeated implantation failure,RIF)是在经过多次IVF-ET后,移植的胚胎没有着床。胚胎植入失败与母体或胚胎因素有关,其中母体因素包括宫腔病理学、血栓形成倾向和免疫因素等。近年来许多方法用于改善和治疗引起RIF的母体因素,如宫腔内灌注β-hCG、阴道用西地那非和静脉输注英脱利匹特注射液等。临床医生应积极探寻导致RIF的病因,并采取积极有效的措施改善RIF患者的妊娠结局。

关键词：反复植入失败(RIF) 母体因素应对策略

Graphene Aerogel Composites with Self‑Organized Nanowires‑Packed Honeycomb Structure for Highly Efficient Electromagnetic Wave Absorption

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Nano-Micro Letters 2025年第2期17卷 533-547页

作者： Xiao You Huiying Ouyang Ruixiang Deng Qiuqi zhang Zhenzhong Xing Xiaowu Chen Qingliang shan Jinshan Yang Shaoming Dong State Key Laboratory of High Performance Ceramics and Superfine Microstructure Shanghai Institute of CeramicsChinese Academy of SciencesShanghai 200050People’s Republic of China Key Laboratory of Inorganic Coating Materials CAS Shanghai Institute of CeramicsChinese Academy of SciencesShanghai 200050People’s Republic of China Structural Ceramics and Composites Engineering Research Center Shanghai Institute of CeramicsChinese Academy of SciencesShanghai 200050People’s Republic of China Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijing 100049People’s Republic of China School of Physical Science and Technology ShanghaiTech UniversityShanghai 201210People’s Republic of China School of Materials Science and Engineering Zhejiang Sci-Tech UniversityHangzhou 310018People’s Republic of China University of Chinese Academy of Sciences Beijing 100039People’s Republic of China

With vigorous developments in nanotechnology,the elaborate regulation of microstructure shows attractive potential in the design of electromagnetic wave ***,a hierarchical porous structure and composite heterogeneous interface are constructed successfully to optimize the electromagnetic loss *** macro–micro-synergistic graphene aerogel formed by the ice template‑assisted 3D printing strategy is cut by silicon carbide nanowires(SiC_(nws))grown in situ,while boron nitride(BN)interfacial structure is introduced on graphene *** unique composite structure forces multiple scattering of incident EMWs,ensuring the combined effects of interfacial polarization,conduction networks,and magnetic-dielectric ***,the as-prepared composites present a minimum reflection loss value of−37.8 dB and a wide effective absorption bandwidth(EAB)of 9.2 GHz(from 8.8 to 18.0 GHz)at 2.5 ***,relying on the intrinsic high-temperature resistance of SiC_(nws) and BN,the EAB also remains above 5.0 GHz after annealing in air environment at 600℃ for 10 h.

关键词： Hierarchical porous structure Interface High-temperature resistance Graphene aerogel composites Electromagnetic wave absorption

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代谢组学在胚胎评估中的应用前景

生殖与避孕 2014年第9期34卷 753-758页

作者：平雅琼张云山天津市中心妇产科医院天津300100

胚胎发育能力的评估在人类辅助生殖技术中起很重要的作用。代谢物组学作为一种非侵入性检测手段可以客观地评价胚胎质量,有良好的重复性;可通过碳水化合物、氨基酸等代谢物评估胚胎及卵母细胞的发育潜能,从而使代谢组学在辅助生殖领域... 详细信息

胚胎发育能力的评估在人类辅助生殖技术中起很重要的作用。代谢物组学作为一种非侵入性检测手段可以客观地评价胚胎质量,有良好的重复性;可通过碳水化合物、氨基酸等代谢物评估胚胎及卵母细胞的发育潜能,从而使代谢组学在辅助生殖领域有广阔的应用前景。

关键词：代谢物组学胚胎卵母细胞

Advances in Graphene‑Based Electrode for Triboelectric Nanogenerator

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Nano-Micro Letters 2025年第1期17卷 378-403页

作者： Bin Xie Yuanhui Guo yun Chen Hao zhang Jiawei Xiao Maoxiang Hou Huilong Liu Li Ma Xin Chen Chingping Wong State Key Laboratory of Precision Electronic Manufacturing Technology and Equipment Guangdong University of TechnologyGuangzhou 510006People’s Republic of China School of Electromechanical Engineering Guangdong University of TechnologyGuangzhou 510006People’s Republic of China School of Materials Science and Engineering Georgia Institute of TechnologyAtlantaGA 30332USA

With the continuous development of wearable electronics,wireless sensor networks and other micro-electronic devices,there is an increasingly urgent need for miniature,flexible and efficient nanopower generation *** nanogenerator(TENG)technology can convert small mechanical energy into electricity,which is expected to address this *** the core component of TENG,the choice of electrode materials significantly affects its *** metal electrode materials often suffer from problems such as durability,which limits the further application of ***,as a novel electrode material,shows excellent prospects for application in TENG owing to its unique structure and excellent electrical *** review systematically summarizes the recent research progress and application prospects of TENGs based on graphene *** precision processing methods of graphene electrodes are introduced,and the applications of graphene electrode-based TENGs in various scenarios as well as the enhancement of graphene electrodes for TENG performance are *** addition,the future development of graphene electrode-based TENGs is also prospectively discussed,aiming to promote the continuous advancement of graphene electrode-based TENGs.

关键词： Triboelectric nanogenerator Precision processing Graphene electrode Self-powered sensor

潮差环境下砂浆氯离子侵蚀对流区厚度的随机性

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港工技术 2016年第5期53卷 1-4页

作者：黄俊张昀张杉庄华夏周巧萍同济大学土木工程学院上海200092 浙江工业大学建筑工程学院浙江杭州310014

通过自然海洋潮差环境下砂浆氯离子侵蚀的现场试验,根据测试得到的砂浆中的自由氯离子浓度分布情况,分析了砂浆中氯离子侵蚀对流区厚度的随机性。结果表明,在自然潮差环境下,砂浆均出现了氯离子侵蚀的对流区;砂浆中氯离子侵蚀对流区厚... 详细信息

通过自然海洋潮差环境下砂浆氯离子侵蚀的现场试验,根据测试得到的砂浆中的自由氯离子浓度分布情况,分析了砂浆中氯离子侵蚀对流区厚度的随机性。结果表明,在自然潮差环境下,砂浆均出现了氯离子侵蚀的对流区;砂浆中氯离子侵蚀对流区厚度均值为4~6 mm;可用正态分布描述砂浆的氯离子侵蚀对流区厚度的随机性;暴露时间、掺合料及水灰比等对其随机特性的影响不明显。

关键词：潮差环境砂浆氯离子对流区随机性

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参数激励下圆柱壳的混沌运动

武汉理工大学学报 2010年第9期32卷 233-236页

作者：王建军韩志军崔艳路国运张善元太原理工大学应用力学与生物医学工程研究所太原030024

考虑有限变形,研究了一端固定一端夹支的弹性圆柱壳在轴向参数激励作用下的混沌运动。不计转动惯性和横向剪切变形,通过Hamilton变分原理导出了圆柱壳轴对称变形的动力控制方程。采用Galerkin原理将其转化为二阶三次非线性微分动力系统... 详细信息

考虑有限变形,研究了一端固定一端夹支的弹性圆柱壳在轴向参数激励作用下的混沌运动。不计转动惯性和横向剪切变形,通过Hamilton变分原理导出了圆柱壳轴对称变形的动力控制方程。采用Galerkin原理将其转化为二阶三次非线性微分动力系统。用Runge-Kutta法对其进行数值计算,通过分岔图、位移时程曲线、相平面图和Poincaré映射描述了系统的运动行为。研究表明:外部激励和外部常载荷对微分动力系统的形式有着明显的影响;随着外部激励的变化,系统会出现定常运动和混沌运动;在外部激励连续取值的某一范围内,系统都会出现混沌运动即会出现混沌层现象。

关键词：圆柱壳参数激励混沌

基于OPC UA技术的Labview与PLC通信

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计算机系统应用 2017年第2期26卷 231-234页

作者：邱云季振山张祖超王勇许张后中国科学院合肥物质科学研究院合肥230031 中国科学技术大学合肥230022

本文提出了在系统中基于OPC UA技术的上位机Labview与下位机PLC-300的通信实现.该通信是在两台PC机间实现的数据交互.一台PC充当客户机,另一台充当服务机,服务器与PLC-300相连.客户机通过UA与服务器连接,进而实现客户机上的Labview与服... 详细信息

本文提出了在系统中基于OPC UA技术的上位机Labview与下位机PLC-300的通信实现.该通信是在两台PC机间实现的数据交互.一台PC充当客户机,另一台充当服务机,服务器与PLC-300相连.客户机通过UA与服务器连接,进而实现客户机上的Labview与服务器相连的PLC进行通信.介绍了在Labview中如何创建可以与UA Server进行安全连接的UA Client,最终实现Labview与PLC的安全通信.在Labview中可以实时显示PLC中的数据变化,并把采集到的数据以文本文件的形式保存起来,供后续观察回放.通过实验验证了该方法的可行性,该系统具有开发周期短,灵活性强,系统稳定的优势.充分验证了利用此方法实现数据通信的可行性.

关键词： OPCUA Labview PLC-300 数据通信

Association of Lysosome Associated Protein Transmembrane 4 Beta Gene Polymorphism with the Risk of Pancreatic Cancer

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Chinese Journal of Cancer Research 2010年第4期22卷 291-295页

作者： shan Wang Qing-yun zhang Key Laboratory of Carcinogenesis and Translational Research（Ministry of Education） Clinical Laboratory Peking University Cancer Hospital ＆ Institute Beijing 100142 China

Objective： Lysosome associated protein transmembrane 4 beta （LAPTM4B） was originally identified as a gene in human hepatocellular carcinoma （HCC）. It was successfully cloned by fluorescence differential display, rapid amplification of cDNA ends （RACE） and reverse transcription polymerase chain reaction （RT-PCR）. Previous study showed that the novel gene played an important role in the occurrence, development, migration and prognosis of tumors. Pancreatic cancer is an aggressive malignancy with the majority of patients dying within one year after diagnosis. This study tries to find out the relationship between lysosome associated protein transmembrane 4 beta gene polymorphism and the susceptibility of pancreatic cancer. Methods： A case-control study was conducted in China, including 58 pancreatic cancer cases and 156 healthy controls. Human genomic DNA was used as the template, polymerase chain reaction （PCR） was used to detect the distribution of LAPTM4B genotype. Analyses Odds ratio （OR） and corresponding 95% confidence interval （95%CI） with logistic regression were performed. Results： Two alleles of LAPTM4B generated three kinds of genotypes in population, ＊1/1, ＊1/2, and ＊2/2. The genotype frequency of ＊1/1, ＊1/2 and ＊2/2 in the pancreatic cancer group were 41.4%, 44.8% and 13.8% respectively, which were not significantly different from those of healthy group （47.4%, 42.9%, 9.6%）（P=0.773, P=0.291）. Also the ＊2 allele frequency of LAPTM4B among pancreatic cancer had no significantly difference with the controls （P=0.354）. When compared to the ＊1 allele, the people with ＊2 allele had no increased risk of pancreatic cancer. Conclusion： The gene polymorphism of LAPTM4B may not influence the susceptibility of pancreatic cancer.

关键词： Polymorphism Lysosome associated protein transmembrane 4 beta Pancreatic cancer Susceptibility