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High-yield and High-efficiency Standardized Cultivation Technique for Wheat Interplanting with Peanuts

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Asian Agricultural Research 2019年第11期11卷 70-72,80页

作者： Yaping zheng Zulin zheng Lili WANG Chunxiao WANG Zeqi LU Wei jiang Hongwei ZANG Hao FENG Yongmei zheng Caibin WANG Shandong Peanut Research Institute Qingdao 266100China Weifang Food and Drug Inspection and Testing Center Weifang 261100China Wendeng District Agricultural Technology Extension Station of Weihai City Weihai 264404China Yantai Academy of Agricultural Sciences Yantai 265500China

Through wheat interplanting with peanuts,it is able to make full use of the light and heat resources in the growing season to achieve high yield of both wheat and peanuts in two seasons of one *** interplanting with peanuts is one of the main cultivation methods of wheat and oil crop double cropping system,and has very broad development prospects in the Huang-Huai-Hai *** paper summarized high-yield the high-efficiency and standardized cultivation techniques for wheat interplanting with peanuts,including crop rotation,proper deep ploughing,balanced fertilization,rational matching of fine varieties,interplanting at suitable time,sowing according to certain specification,and enhancing the field *** can be used as reference for high-yield and high-efficiency standardized cultivation technique for wheat interplanting with peanuts.

关键词： Peanut Wheat interplanting High yield cultivation

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问题图式获得理论及其在教学中的应用

南京师大学报（社会科学版） 2006年第4期 111-115页

作者：邓铸姜子云南京师范大学教育科学学院江苏南京210097

问题图式是能在问题解决过程中起核心作用的大的知识单元,它使我们对问题解决表征机制的认识更为深刻。在阐述问题图式获得机制方面,研究者提出了结构映射理论和语用图式理论,同时发现类比问题解决和样例学习是获得问题图式的两条有效... 详细信息

问题图式是能在问题解决过程中起核心作用的大的知识单元,它使我们对问题解决表征机制的认识更为深刻。在阐述问题图式获得机制方面,研究者提出了结构映射理论和语用图式理论,同时发现类比问题解决和样例学习是获得问题图式的两条有效途径。因此,要想在教学中有效地促进学生问题图式的获得,就要增加学生类比问题解决和样例学习的机会,比如提倡图式图教学;在样例教学初期,给予学生适当的线索提示;迁移教学中增加源问题类比物的数量等。

关键词：问题图式结构映射理论语用图式理论样例学习

The Application of Quantum Dots Double-Labeling Immunofluorescence Technology in Detection of PR and CD146 in Paraffin-Embedded Tissue Sections of Endometrioid Adenocarcinoma

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Yangtze Medicine 2017年第1期1卷 1-7页

作者： Jianping zheng Qing Huang Lei Zhang Yong Chen Jinpeng jiang Cunjian Yi Department of Obstetrics and Gynecology The First Affiliated Hospital of Yangtze University Jinzhou China

Objective: The aim was to detect the expression of PR and CD146 in paraf-fin-embedded tissue sections of endometrioid adenocarcinoma by using QDs double-labeling immunofluorescence, and evaluate the applied value of QDs double-labeling immunofluorescence in endometrioid adenocarcinoma. Methods: To detect the expression of PR and CD146 on 140 cases of paraffin-embedded tissue sections of endometrioid adenocarcinoma by using QDS double-labeling immunofluorescence. Results: The co-expression of PR and CD146 in the endometrioid adenocarcinoma can be detected by QDs double-labeling immunofluorescence, and there was no correlation between them (P > 0.05). Conclusion: QDs double-labeling immunofluorescence can detect the localization and co-expression of PR and CD146 in the endometrioid adenocarcinoma.

关键词： Endometrioid Adenocarcinoma PR CD146 QDs Double-Labeling Immunofluorescence

SEQUENCE　BOUNDRIES　OF　THE　PALEOGENE　IN　THE　SHOAL　AREA　OF　JIYANG　DEPRESSION

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Scientia Geologica Sinica 1995年第4期 475-480页

作者： Qian zheng jiang Zaixing Li Chun and Cao Yingchang (University of Petroleum, Dongying 257062)

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ＳＥＱＵＥＮＣＥＢＯＵＮＤＡＲＩＥＳＯＦＴＨＥＰＡＬＥＯＧＥＮＥＩＮＴＨＥＳＨＯＡＬＡＲＥＡＯＦＪＩＹＡＮＧＤＥＰＲＥＳＳＩＯＮ￥ＱｉａｎＺｈｅｎｇ；ＪｉａｎｇＺａｉｘｉｎｇ；ＬｉＣｈｕｎａｎｄＣａｏＹｉｎｇｃｈａｎｇ（ＵｎｉｖｅｒｓｉｔｙｏｆＰｅｔ...

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Antiangiogenic therapy with bevacizumab in recurrent malignant gliomas： analysis of the response and core pathway aberrations

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Chinese Medical Journal 2009年第11期122卷 1250-1254页

作者： ZHANG Wei QIU Xiao-guang CHEN Bao-shi LI Shou-wei CUI yun REN Huan jiang Tao Department of Neurosurgery Beijing Tiantan Hospital Capital Medical University Beijing 100050 China Department of Radiotherapy Beijing Tiantan Hospital Capital Medical University Beijing 100050 China Department of Neuropathology Beijing Neurosurgical Institute Beijing 100050 China Department of Immunology College of Basic Medical Science Harbin Medical University Harbin 150086 China

Background Bevacizumab, a humanized monoclonal antibody against vascular endothelial growth factor, has shown promising activity in recurrent malignant gliomas. We reported the treatment response for the combination of bevacizumab and chemotherapy in a series of six patients with recurrent malignant glioma and investigated the molecular alterations in cancer pathways using the surgical biopsies from these patients. Methods Standard therapy with primary resection followed by adjuvant chemoradiotherapy had failed in all patients. Bevacizumab was administered at a dose of 10 mg/kg every 2 weeks. Concomitantly, four patients received temozolomide （50 mg·m^-2·d^-1）, one patient irinotecan （125 mg/m^2 every 2 weeks） and one patient topotecan （1.2 mg·m^-2·d^-1）. Response to therapy was mainly determined by magnetic resonance imaging. The expression of Ras, phosphorylated mitogen activated protein kinase （p-MAPK）, phosphorylated AKT （p-AKT）, phosphorylated mammalian target of rapamycin （p-mTOR） and phosphorylated signal transducer and activator of transcription 3 （p-STAT3） were semiquantitatively assessed by immunohistochemistry using surgical biopsies before the initial treatment. Results Five of the six patients had a radiographic response. Three were complete response, and two were partial response. Only one patient had progressive disease. The 6-month progession-free survival （PFS） was 33% and the median PFS was 15 weeks, with a range of 6 to more than 60 weeks. Of the three core pathways analyzed in this study, the Ras/MAPK and phosphatidylinositol-3-kinase （PI3K）/AKT/mTOR pathways were more likely to be associated with the treatment response to bevacizumab. In two younger patients （ages 〈50） with complete response, simultaneous overexpression of p-MAPK, p-AKT and p-mTOR might be the crucial feature. Conclusions Bevacizumab in combination with chemotherapeutic agents may be an effective strategy for patients with recurrent malignant glioma. Activated MAPK and AKT might

关键词： glioma molecularly targeted therapy bevacizumab antiangiogenic therapy

Fixed-point Monitoring of Vaccine Immune Effects on Severe Animal Diseases in Livestock and Poultry Breeding Fields

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Animal Husbandry and Feed Science 2014年第5期6卷 245-248,253页

作者： Zhang Sihua Ruan zheng Yin Weili Wan yun Zhou Hui Gong Shiyu Wuhan Center for Severe Animal Diseases Control and Prevention Yantai Entry-Exit Inspection and Quarantine Bureau State Key Laboratory of Agricultural Microbiology Huazhong Agricultural University

In order to reveal the immune antibody levels and immune effect of livestock and poultry in the locality,we performed antibody surveillance on severe animal diseases in 17 livestock and poultry fields in six administrative districts of Wuhan City. The results showed that the vaccines had a good protective efficacy on highly pathogenic avian influenza( HPAI) and Newcastle disease( ND) in Wuhan City. The whole antibody levels kept above the ministerial standard( > 70%).However,the vaccine immunity of porcine reproductive and respiratory syndrome( PRRS),swine fever( SF) and foot and mouth disease( FMD) was still poorly protective. The data indicated that the vaccines are protecting the severe animal diseases well,but there are still some potential security holes in some administrative districts.

关键词： Livestock and poultry field Mandatory vaccination Severe animal diseases Antibody surveillance Immunity

Stress Relaxation in Nanostructured Copper:Experiments and Simulations

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Stress Relaxation in Nanostructured Copper:Experiments and S...

第十八届全国疲劳与断裂学术会议

作者： Xu-Sheng Yang yun-jiang Wang Tong-Yi Zhang Department of Mechanical and Aerospace Engineering The Hong Kong University of Science and Technology State Key Laboratory of Nonlinear Mechanics Institute of MechanicsChinese Academy of Sciences Shanghai University Materials Genome Institute and Shanghai Materials Genome Institute Shanghai University

In the present work,stress relaxation tests,high-resolution transmission electron microscopy（HRTEM） and molecular dynamics（MD） simulations were conducted on coarse-grained（cg）,nanograined（ng） and nanotwinned（nt） copper at temperatures ranging from room temperature to 75 ℃.The comprehensive investigations provide sufficient information for the building-up of a formula to describe the time,stress and temperature-dependent deformation and clarify the relationship among the strain rate sensitivity parameter,stress exponent and activation *** experimental and simulation results also suggest that under high stress level,dislocation-mediated plastic deformation is predominant in all cg,ng and nt *** low stress level,the grain boundary（GB） diffusion-associated deformation is dominant in the ng and cg specimens,whereas twin boundary（TB） migration,i.e.,twinning and detwinning with parallel partial dislocations,governs the time,stress and temperature-dependent deformation in the nt specimens.

关键词： Stress Relaxation Nanotwin Copper HRTEM Atomistic Simulations

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趋新求变与学科融合:论丁骕的西南民族研究

广西民族大学学报（哲学社会科学版） 2019年第4期41卷 73-81页

作者：蒋正虎云南民族大学人文学院

从20世纪30年代中期到40年代,丁骕试图以人种学和历史记载为核心,建立贯通性的西南民族起源及其流变体系。丁骕的西南民族研究,以求新和学科融合为主要特点。求新方面,丁骕在民族研究过程中始终保持求新求变的态度,不囿于成见,敢否定自... 详细信息

从20世纪30年代中期到40年代,丁骕试图以人种学和历史记载为核心,建立贯通性的西南民族起源及其流变体系。丁骕的西南民族研究,以求新和学科融合为主要特点。求新方面,丁骕在民族研究过程中始终保持求新求变的态度,不囿于成见,敢否定自我。学科融合方面,丁骕以人种地理学为起点,以历史记载为主干,先后融合历史学、人类学、语言学、地理学等学科的理论与方法,系统阐述西南或云南民族的源流,促进了当时西南民族研究甚至整个边疆研究的开展,深化了当时国人对西南少数民族、对于整个中华民族的认知。对今天的学术研究,也提供了有益的启示。

关键词：丁骕西南民族研究人种地理学学科融合

Anti-inflammatory properties of lipoxin A4 protect against diabetes mellitus complicated by focal cerebral ischemia/reperfusion injury

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Neural Regeneration Research 2016年第4期11卷 636-640页

作者： jiang-quan Han Cheng-ling Liu zheng-yuan Wang Ling Liu Ling Cheng Ya-dan Fan Department of Neurology Fifth Affiliated Hospital of Zunyi Medical College

Lipoxin A4 can alleviate cerebral ischemia/reperfusion injury by reducing the inflammatory reaction,but it is currently unclear whether it has a protective effect on diabetes mellitus complicated by focal cerebral ischemia/reperfusion *** this study,we established rat models of diabetes mellitus using an intraperitoneal injection of *** then induced focal cerebral ischemia/reperfusion injury by occlusion of the middle cerebral artery for 2 hours and reperfusion for 24 *** administration of lipoxin A4 via the lateral ventricle,infarction volume was reduced,the expression levels of pro-inflammatory factors tumor necrosis factor alpha and nuclear factor-kappa B in the cerebral cortex were decreased,and neurological functioning was *** findings suggest that lipoxin A4 has strong neuroprotective effects in diabetes mellitus complicated by focal cerebral ischemia/reperfusion injury and that the underlying mechanism is related to the anti-inflammatory action of lipoxin A4.

关键词： nerve regeneration inflammatory response tumor necrosis factor alpha nuclear factor-kappa B neural regeneration