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The Consistency of LSE Estimators in Partial Linear Regression Models under Mixing Random Errors

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Acta Mathematica Sinica,English Series 2024年第5期40卷 1244-1272页

作者： yun bao YAO Yu Tan LÜ Chao LU Wei WANG Xue Jun WANG School of Mathematical Sciences Anhui UniversityHefei 230601P.R.China School of Big Data and Artificial Intelligence Chizhou UniversityChizhou 247000P.R.China School of Big Data and Statistics Anhui UniversityHefei 230601P.R.China

In this paper,we consider the partial linear regression model y_(i)=x_(i)β^(*)+g(ti)+ε_(i),i=1,2,...,n,where(x_(i),ti)are known fixed design points,g(·)is an unknown function,andβ^(*)is an unknown parameter to be estimated,random errorsε_(i)are(α,β)-mix_(i)ng random *** p-th(p>1)mean consistency,strong consistency and complete consistency for least squares estimators ofβ^(*)and g(·)are investigated under some mild *** addition,a numerical simulation is carried out to study the finite sample performance of the theoretical ***,a real data analysis is provided to further verify the effect of the model.

关键词： (α,β)-mixing random variables partial linear regression model least squares estimator consistency

Effects of rare earth elements on inclusions, microstructure and impact toughness of spring steel

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Journal of Iron and Steel Research(International) 2024年第4期31卷 933-944页

作者： Chun-lei Hao Chao-yun Yang Peng Liu Yi-kun Luan bao-guang Sang Shenyang National Laboratory for Materials Science Institute of Metal ResearchChinese Academy of SciencesShenyang 110016LiaoningChina School of Mechanical Engineering and Automation Dalian Polytechnic UniversityDalian 116034LiaoningChina

Spring steel is an indispensable basic part manufacturing material in mechanical equipment,which is widely used in transportation tools such as automobiles,railways,construction machinery and other *** effects of rare earth(RE)on inclusions,microstructure,carbides and impact toughness of 50CrV spring steel were studied by means of optical microscope,scanning electron microscope,transmission electron microscope and impact *** results show that the addition of rare earth can modify the main MnS and Al_(2)O_(3) inclusions in steel to form spherical or near-spherical rare earth inclusions,and the size of inclusions is significantly *** the quenched structure,the size of martensite slab becomes smaller and the structure is *** tempering,the carbide changes from sheet to ellipse,which makes it easier for spring steel to form stress concentration cracks under *** becomes finer and more dispersed,which leads to better pinning of grain boundaries and smaller grain *** impact toughness of 50CrV-RE spring steel increased from 21 to 41 J by 95%due to the improvement of inclusions,microstructure and carbides by rare *** is possible to improve the strength and toughness of spring steel for the improvement of railway running speed and the development of vehicle lightweight in China.

关键词： Rare earth-Spring steel Inclusion Microstructure Impact toughness

UV-Based Advanced Oxidation Processes for Antibiotic Resistance Control: Efficiency, Influencing Factors, and Energy Consumption

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Engineering 2024年第6期37卷 27-39页

作者： Jiarui Han Wanxin Li yun Yang Xuanwei zha.g Siyu bao Xiangru zha.g Tong zha.g Kenneth Mei Yee Leung Department of Civil and Environment Engineering The Hong Kong University of Science and TechnologyHong Kong 999077China Department of Civil Engineering The University of Hong KongHong Kong 999077China State Key Laboratory of Marine Pollution and Department of Chemistry City University of Hong KongHong Kong 999077China

Antibiotic resistant bacteria(ARB)with antibiotic resistance genes(ARGs)can reduce or eliminate the effectiveness of antibiotics and thus threaten human *** United Nations Environment Programme considers antibiotic resistance the first of six emerging issues of *** oxidation processes(AOPs)that combine ultraviolet(UV)irradiation and chemical oxidation(primarily chlorine,hydrogen peroxide,and persulfate)have attracted increasing interest as advanced water and wastewater treatment *** integrated technologies have been reported to significantly elevate the efficiencies of ARB inactivation and ARG degradation compared with direct UV irradiation or chemical oxidation alone due to the generation of multiple reactive *** this study,the performance and underlying mechanisms of UV/chlorine,UV/hydrogen peroxide,and UV/persulfate processes for controlling ARB and ARGs were reviewed based on recent *** affecting the process-specific efficiency in controlling ARB and ARGs were discussed,including biotic factors,oxidant dose,UV fluence,pH,and water matrix *** addition,the cost-effectiveness of the UV-based AOPs was evaluated using the concept of electrical energy per *** UV/chlorine process exhibited a higher efficiency with lower energy consumption than other UV-based AOPs in the wastewater matrix,indicating its potential for ARB inactivation and ARG degradation in wastewater *** studies are required to address the trade-off between toxic byproduct formation and the energy efficiency of the UV/chlorine process in real wastewater to facilitate its optimization and application in the control of ARB and ARGs.

关键词： Advanced oxidation processes Ultraviolet/chlorine Ultraviolet/hydrogen peroxide Ultraviolet/persulfate Antibiotic resistant bacteria Antibiotic resistance genes

Elimination of cracks in stainless steel casings via 3D printed sand molds with an internal topology structure

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China Foundry 2024年第4期21卷 319-326页

作者： Jun-hang Xu bao-zhi Li zha.-wei Song yun-bao Gao Jing-ming Li Yu Wang Qiu-lin Wen Heng Cao Zeng-rui Wang National Key Laboratory of Advanced Casting Technologies Shenyang 110022China Shenyang Research Institute of Foundry Co. Ltd.CAMShenyang 110022China

The important supporting component in a gas turbine is the casing,which has the characteristics of large size,complex structure,and thin *** the context of existing 3DP sand casting processes,casting crack defects are prone to *** leads to an increase in the scrap rate of casings,causing significant resource ***,the presence of cracks poses a significant safety hazard after the casings are put into *** generation of different types of crack defects in stainless steel casings is closely related to casting stress and the high-temperature concession of the sand ***,the types and causes of cracks in stainless steel casing products,based on their structural characteristics,were systematically *** sand molds with different internal topology designs were printed using the 3DP technology to investigate the impact of sand mold structures on high-temperature *** optimal sand mold structure was used to cast casings,and the crack suppression effect was verified by analyzing its eddy current testing *** experimental results indicate that the skeleton structure has an excellent effect on suppressing cracks in the *** research holds important theoretical and engineering significance in improving the quality of casing castings and reducing production costs.

关键词： gas turbine casing crack defects 3D printed sand mold topological structure high-temperature concession

Artemordins A-S, Cadinane-Type Sesquiterpenoid Dimers from Artemisia ordosica and Their Antihepatoma Activities

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Chinese Journal of Chemistry 2024年第13期42卷 1493-1508页

作者： Yuan Wang Tian-Ze Li yun-bao Ma Chang-An Geng Yong-Cui Wang Ji-Jun Chen State Key Laboratory of Phytochemistry and Plant Resources in West China Kunming Institute of BotanyChinese Academy of SciencesKunmingYunnan 650201China University of Chinese Academy of Sciences Beijing 100049China

Nineteen new cadinane-involving sesquiterpenoid dimers,artemordins A-S(1-—19),together with 13 known SDs(20-32)were isolated from Artemisia *** structures and absolute configurations were established by comprehensive spectral analyses,X-ray single crystal diffraction,theoretical ECD,and NMR ***,artemordins A-F(1—6)were the first examples of two cadinane units constructed by unprecedented C-3−C-15′or C-3−C-13′single bond with an oxido-rearranged 6/5/6/6 fused ring system;artemordins G-K(7-11)were biogenetically connected by[4+2]cycloaddition reaction and artemordins G-J(7-10)possessed a novel 5/6/6/6/6/6/5-heptacyclic fused ring *** L-S(12-19)were formed by esterification,which involved three different types of *** assay suggested that the most active compounds,artemordins B and H(2 and 8),exhibited inhibitory activities on three hepatoma cell lines with IC50 values of 26.9 and 25.1μmol/L(HepG2),29.5 and 18.3μmol/L(Huh7),19.7 and 15.7μmol/L(SK-Hep-1).

关键词： Artemisia ordosica Artemordins A-s Cadinane-type sesquiterpenoid dimers Antihepatoma activities Terpenoids Natural products Cytotoxicity

Design and fabrication of lightweight AlCrFeNiTi_(x) compositionally complex alloys with exceptional specific strength

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Rare Metals 2024年第7期43卷 3314-3328页

作者： Jun-Zhi Li Wei-Zong bao Jie Chen Bo-Hua Yu Kun Zuo Tian Gao Ze-yun Cai Guo-Qiang Xie School of Materials Science and Engineering Harbin Institute of Technology(Shenzhen)Shenzhen 518055China State Key Laboratory of Advanced Welding and Joining Harbin Institute of TechnologyHarbin 150001China

This study focuses on compositionally complex alloys(CCAs),aiming to achieve a balance between high strength and low density for new energy and aerospace *** composition of AlCrFeNiTi_(x) CCAs is strategically guided by employing density functional theory and the theoretical design of thermodynamic *** CCAs,particularly AlCrFeNiTi_(0.25) alloy,demonstrate remarkable specific yield strength(1640.8 MPa) and 22.7% maximum *** incorporation of Ti facilitates the formation of lightweight and high-strength L2_(1)phase,contributing to the overall high specific *** effects of grain boundary strengthening,solid solution strengthening,Orowan strengthening and Peierls flow stress further enhance *** exploration of micros tructural changes during fracture reveals the role of ordered phases in suppressing crack propagation and absorbing energy within disordered phases,thereby improving the toughness and fracture resistance of *** methods and discoveries establish a robust foundation for advancing the development of novel lightweight CCAs.

关键词： Lightweight Compositionally complex alloys Specific yield strength

Long Non-coding RNA PCED1B Antisense RNA 1 Promotes Cell Proliferation and Invasion in Hepatocellular Carcinoma by Regulating the MicroRNA-34a/CD44 Axis

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Current Medical Science 2024年第3期44卷 503-511页

作者： Jian-gang BI Qi LI Yu-sheng GUO Li-ping LIU Shi-yun bao Ping XU Department of Hepatobiliary and Pancreatic Surgery Shenzhen People's HospitalThe Second Clinical Medical CollegeJinan UniversityThe First Affiliated HospitalSouthern University of Science and TechnologyShenzhen 518020China Department of Endocrinology Shenzhen People's HospitalThe Second Clinical Medical CollegeJinan UniversityThe First Affiliated HospitalSouthern University of Science and TechnologyShenzhen 518020China

Objective This study aimed to examine the role of long non-coding RNA PCED1B antisense RNA 1(PCED1B-AS1)in the development of hepatocellular carcinoma(HCC).Methods A total of 62 pairs of HCC tissues and adjacent non-tumor tissues were obtained from 62 HCC *** interactions of PCED1B-AS1 and microRNA-34a(miR-34a)were detected by dual luciferase activity assay and RNA pull-down *** RNA expression levels of PCED1B-AS1,miR-34a and CD44 were detected by RT-qPCR,and the protein expression level of CD44 was determined by Western *** cell proliferation was detected by cell proliferation assay,and the cell invasion and migration by transwell invasion *** HCC tumor growth after PCED1B-AS1 was downregulated was determined by in vivo animal *** PCED1B-AS1 was highly expressed in HCC tissues,which was associated with poor survival of HCC ***,PCED1B-AS1 interacted with miR-34a in HCC cells,but they did not regulate the expression of each ***,PCED1B-AS1 increased the expression level of CD44,which was targeted by *** cell proliferation and invasion assay revealed that miR-34a inhibited the proliferation and invasion of HCC in vitro,while CD44 exhibited the opposite ***,PCED1B-AS1 suppressed the role of ***,the knockdown of PCED1B-AS1 repressed the HCC tumor growth in nude mice in *** PCED1B-AS1 may play an oncogenic role by regulating the miR-34a/CD44 axis in HCC.

关键词： long non-coding RNA PCED1B antisense RNA 1(PCED1B-AS1) hepatocellular carcinoma microRNA-34a(miR-34a) CD44 proliferation invasion

The technology of radio frequency fingerprint identification based on deep learning for 5G application

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Security and Safety

Security and Safety 2024年第1期 47-67页

作者： yun Lin Hanhong Wang Haoran zha College of Information and Communication Engineering Harbin Engineering University

User Equipment(UE) authentication holds paramount importance in upholding the security of wireless networks. A nascent technology, Radio Frequency Fingerprint Identification(RFFI), is gaining prominence as a means to bolster network security *** expedite the integration of RFFI within fifth-generation(5G) networks, this research undertakes the creation of a comprehensive link-level simulation platform tailored for 5G scenarios. The devised platform emulates various device impairments, including an oscillator, IQ modulator, and power amplifier(PA) nonlinearities, alongside simulating channel distortions. Consequent to this, a plausibility analysis is executed, intertwining transmitter device impairments with 3rd Generation Partnership Project(3GPP) new radio(NR) protocols. Subsequently, an exhaustive exploration is conducted to assess the impact of transmitter impairments, deep neural networks(DNNs), and channel effects on RF fingerprinting performance. Notably, under a signal-to-noise ratio(SNR) of 15 d B, the deep learning approach demonstrates the capability to accurately classify 100 UEs with a commendable 91% accuracy rate. Through a multifaceted evaluation, it is ascertained that the Attention-based network architecture emerges as the optimal choice for the RFFI task, serving as the new benchmark model for RFFI applications.

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Myricetin induces M2 macrophage polarization to alleviate renal tubulointerstitial fibrosis in diabetic nephropathy via PI3K/Akt pathway

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World Journal of Diabetes 2024年第1期15卷 105-125页

作者： Wei-Long Xu Pei-Pei Zhou Xu Yu Ting Tian Jin-Jing bao Chang-Rong Ni Min zha.Xiao Wu Jiang-Yi Yu Department of Endocrinology Jiangsu Province Hospital of Chinese MedicineThe Affiliated Hospital of Nanjing University of Chinese MedicineNanjing 210000Jiangsu ProvinceChina Department of Pharmacy Jiangsu Province Hospital of Chinese MedicineThe Affiliated Hospital of Nanjing University of Chinese MedicineNanjing 210000Jiangsu ProvinceChina Department of Pneumology Jiangsu Province Hospital of Chinese MedicineThe Affiliated Hospital of Nanjing University of Chinese MedicineNanjing 210000Jiangsu ProvinceChina

BACKGROUND Development of end-stage renal disease is predominantly attributed to diabetic nephropathy(DN).Previous studies have indicated that myricetin possesses the potential to mitigate the pathological alterations observed in renal ***-theless,the precise molecular mechanism through which myricetin influences the progression of DN remains *** To investigate the effects of myricetin on DN and explore its potential therapeutic *** Db/db mice were administered myricetin intragastrically on a daily basis at doses of 50 mg/kg or 100 mg/kg for a duration of 12 ***,blood and urine indexes were assessed,along with examination of renal tissue *** morphology and fibrosis were evaluated using various staining techniques including hematoxylin and eosin,periodic acid–Schiff,Masson’s trichrome,and ***,high-glucose culturing was conducted on the RAW 264.7 cell line,treated with 25 mM myricetin or co-administered with the PI3K/Akt inhibitor LY294002 for a period of 24 *** both in vivo and in vitro settings,quantification of inflammation factor levels was conducted using western blotting,real-time qPCR and *** In db/db mice,administration of myricetin led to a mitigating effect on DN-induced renal dysfunction and ***,we observed a significant reduction in expressions of the kidney injury markers kidney injury molecule-1 and neutrophil gelatinase associated lipocalin,along with a decrease in expressions of inflammatory cytokine-related ***,myricetin treatment effectively inhibited the up-regulation of tumor necrosis factor-alpha,interleukin-6,and interluekin-1βinduced by high glucose in RAW 264.7 ***,myricetin modulated the M1-type polarization of the RAW 264.7 *** docking and bioinformatic analyses revealed Akt as the target of *** protective effect of myricetin was nullified upon blocking the polarization of RAW 264.7 via inh

关键词： Myricetin Diabetic nephropathy PI3K/Akt pathway Renal tubulointerstitial fibrosis Macrophage Polarization