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Impacts of the annual cycle of background SST in the tropical Pacific on the phase and amplitude of ENSO

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Atmospheric and Oceanic Science Letters 2025年第1期18卷 12-17页

作者： song Jiang Congwen Zhu ning Jiang State Key Laboratory of Severe Weather(LASW) Chinese Academy of Meteorological SciencesBeijingChina College of Earth and Planetary Sciences University of Chinese Academy of SciencesBeijingChina

The dominant annual cycle of sea surface temperature(SST)in the tropical Pacific exhibits an antisymmetric mode,which explains 83.4%total variance,and serves as a background of El Niño-Southern Oscillation(ENSO).However,there is no consensus yet on its anomalous impacts on the phase and amplitude of *** on data during 1982-2022,results show that anomalies of the antisymmetric mode can affect the evolution of ENSO on the interannual scale via Bjerknes feedback,in which the positive(negative)phase of the antisymmetric mode can strengthen El Niño(La Niña)in boreal winter via an earlier(delayed)seasonal cycle transition and larger(smaller)annual *** magnitude of the SST anomalies in the equatorial eastern Pacific can reach more than±0.3◦C,regulated by the changes in the antisymmetric mode based on random sensitivity *** reveal the spatial pattern of the annual cycle associated with the seasonal phase-locking of ENSO evolution and provide new insight into the impact of the annual cycle of background SST on ENSO,which possibly carries important implications for forecasting ENSO.

关键词： Annual cycle SST anomaly Antisymmetric mode ENSO

The pivotal role of microglia in injury and the prognosis of subarachnoid hemorrhage

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Neural Regeneration Research 2025年第7期20卷 1829-1848页

作者： Wenjing ning Shi Lv Qian Wang Yuzhen Xu Department of Rehabilitation The Second Affiliated Hospital of Shandong First Medical UniversityTaianShandong ProvinceChina Department of Central Laboratory The Affiliated Taian City Central Hospital of Qingdao UniversityTaianShandong ProvinceChina

Subarachnoid hemorrhage leads to a series of pathological changes,including vascular spasm,cellular apoptosis,blood–brain barrier damage,cerebral edema,and white matter ***,which are the key immune cells in the central nervous system,maintain homeostasis in the neural environment,support neurons,mediate apoptosis,participate in immune regulation,and have neuroprotective *** evidence has shown that microglia play a pivotal role in the pathogenesis of subarachnoid hemorrhage and affect the process of injury and the prognosis of subarachnoid ***,microglia play certain neuroprotective roles in the recovery phase of subarachnoid *** approaches aimed at modulating microglia function are believed to attenuate subarachnoid hemorrhage *** provides new targets and ideas for the treatment of subarachnoid ***,an in-depth and comprehensive summary of the role of microglia after subarachnoid hemorrhage is still *** review describes the activation of microglia after subarachnoid hemorrhage and their roles in the pathological processes of vasospasm,neuroinflammation,neuronal apoptosis,blood–brain barrier disruption,cerebral edema,and cerebral white matter *** also discusses the neuroprotective roles of microglia during recovery from subarachnoid hemorrhage and therapeutic advances aimed at modulating microglial function after subarachnoid ***,microglia in subarachnoid hemorrhage are targeted with TLR inhibitors,nuclear factor-κB and STAT3 pathway inhibitors,glycine/tyrosine kinases,NLRP3 signaling pathway inhibitors,Gasdermin D inhibitors,vincristine receptorαreceptor agonists,ferroptosis inhibitors,genetic modification techniques,stem cell therapies,and traditional Chinese ***,most of these are still being evaluated at the laboratory *** clinical studies and data on subarachnoid hemorrhage are required to improve the treatment of subarachnoid hemor

关键词： apoptosis blood–brain barrier brain edema microglia neuroinflammation neuron neuroprotection subarachnoid hemorrhage vasoconstriction white matter injury

Interconnections between diabetic corneal neuropathy and diabetic retinopathy:diagnostic and therapeutic implications

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Neural Regeneration Research 2025年第8期20卷 2169-2180页

作者： Mingyi Yu Faith Teo En ning Chang Liu Yu-Chi Liu Tissue Engineering and Stem Cell Group Singapore Eye Research InstituteSingapore Yong Loo Lin School of Medicine National University of SingaporeSingapore Department of Cornea and External Eye Disease Singapore National Eye CenterSingapore Ophthalmology and Visual Sciences Academic Clinical Program Duke-NUS Medical SchoolSingapore

Diabetic corneal neuropathy and diabetic retinopathy are ocular complications occurring in the context of diabetes *** corneal neuropathy refers to the progressive damage of corneal *** retinopathy has traditionally been considered as damage to the retinal ***,growing evidence suggests that diabetic retinopathy is a complex neurovascular disorder resulting from dysfunction of the neurovascular unit,which includes both the retinal vascular structures and neural *** retinopathy is one of the leading causes of blindness and is frequently screened for as part of diabetic ocular ***,diabetic corneal neuropathy is commonly overlooked and underdiagnosed,leading to severe ocular surface *** studies have found that these two conditions tend to occur together,and they share similarities in their pathogenesis pathways,being triggered by a status of chronic *** review aims to discuss the interconnection between diabetic corneal neuropathy and diabetic retinopathy,whether diabetic corneal neuropathy precedes diabetic retinopathy,as well as the relation between the stage of diabetic retinopathy and the severity of corneal *** also endeavor to explore the relevance of a corneal screening in diabetic eyes and the possibility of using corneal nerve measurements to monitor the progression of diabetic retinopathy.

关键词： cornea corneal nerves diabetes diabetic corneal neuropathy diabetic retinopathy retina

Stability of twins in Mg alloys-A short review

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Journal of Magnesium and Alloys 2020年第1期8卷 66-77页

作者： Tingting Liu Qingshan Yang ning Guo yun Lu Bo song School of Materials and Energy Southwest UniversityChongqing 400715China School of Metallurgy and Materials Engineering Chongqing University of Science and TechnologyChongqing 401331China Graduate School of Science and Engineering Chiba UniversityChiba 263-8522Japan

In this article,the stability of twins,especially{10–12}twins,in Mg alloys was critically *** the last decade,pre-twinning is considered to be an effective method for adjusting the microstructure and properties of wrought Mg ***,formation of twin-texture can remarkably improve formability of rolled Mg ***,the stability of{10–12}twins determines the effect of this *** work revealed that initial{10–12}twins may either grow or shrink under further deformation,and may be removed by static recrystallization under thermal *** is considered that improving the stability of twin structure could enhance the contribution of twin-texture on subsequent plastic *** on this background,stress stability and thermal stability of{10–12}twin structure were summarized and reviewed in this ***,a few critical scientific problems in this research field were pointed out.©2020 Published by Elsevier *** behalf of Chongqing University.

关键词： Mg alloys Twin structure Stability Texture Recrystallization

Ultraviolet Nonlinear Optical Crystals inπ-Conjugated System

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Chinese Journal of Structural Chemistry 2020年第12期39卷 2148-2156,2055页

作者： song yun-Xia LUO Min YE ning School of Electronic Electrical Engineering and PhysicsFujian University of TechnologyFuzhou 350108China Key Laboratory of Optoelectronic Materials Chemistry and Physics Fujian Institute of Research on the Structure of MatterChinese Academy of SciencesFuzhou 350002China

UV nonlinear optical(NLO)crystals are essential materials for UV solid state laser *** date,frequency conversion in UV region is mainly dependent on borates with planar BO3 or B3O6 *** the practical applications require more and more high comprehensive properties of crystals,it is urgent to develop new UV NLO ***,it is more and more difficult to find new borate NLO crystals because borate NLO crystals have been studied for several ***,it is important to search new systems for the exploration of UV NLO *** on the relationship between the microstructure and properties of the groups,we proposed that inorganic(CO3)2-and(NO3)-groups can be as new NLO active units for UV NLO crystals because they haveπ-conjugated ***,our group have performed related work in carbonate and nitrate systems in recent years,which resulted in finding some excellent carbonates and nitrates NLO *** addition,we have recently expanded the research field from inorganic to organicπ-conjugated systems,such as *** mini review will introduce the research results of our team in the field of UV NLO crystals including carbonates,nitrates and cyanurates in recent years.

关键词： carbonates nitrates hydro-isocyanurate UV nonlinear optical crystal

Effect of austenitizing temperature on microstructure in 16Mn steel treated by cerium

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International Journal of Minerals,Metallurgy and Materials 2011年第6期18卷 652-658页

作者： Bin Wen Bo song ning Pan Qing-yun Hu Jing-hong Mao State Key Lab of Advanced Metallurgy University of Science and Technology Beijing Beijing 100083 China School of Metallurgical and Ecological Engineering University of Science and Technology Beijing Beijing 100083 China School of Materials Science and Engineering University of Science and Technology Beijing Beijing 100083 China

The change of inclusions and microstructure of 16Mn steel treated by Ce were observed,and the effect of austenitizing temperature on the microstructure was also *** results show that the inclusions are transformed from Si-Mn-Al composite oxide and MnS into AlCeO3,Ce2O2S,and MnS composite inclusions after being treated by *** of intragranular ferrites are formed in 16Mn steel containing～0.017wt% Ce.A large amount of intragranular acicular ferrites are formed after being austenitized for 20min at 1473 *** prior austenite grain size fit for the formation of intragranular acicular ferrites is about 120μm.

关键词： steel metallurgy inclusions ferrite austenite grain size

Effect of Gd on microstructure and refinement performance of Al-5Ti-B alloy

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China Foundry 2021年第3期18卷 223-228页

作者： Dong-song Yin ning Zhang Ke-ju Chen yun-long Zhang School of Materials Science and Engineering Heilongjiang University of Science and TechnologyHaerbin 150022China School of Materials Science and Engineering Jiamusi UniversityJiamusi 154007China

Al-5Ti-B and Al-5Ti-B-Gd master alloy refiners were fabricated by fluorine salt casting *** microstructure and phase constitution of the master alloys were investigated by scanning electron microscopy (SEM),transmission electron microscopy (TEM) and X-ray diffraction (XRD).The results show that Al-Ti-B alloy refiner consists of Al_(3)Ti phase and TiB2 *** Gd is introduced into the intermediate alloy,Ti_(2)Al_(20)Gd phase appears in the alloy,the size of Al_(3)Ti is significantly reduced,and Ti-Al-Gd phase is found in the edge of Al_(3)Ti *** the same time,some independent Ti-Al-Gd phases appear in local areas,which are Ti_(2)Al_(20)Gd phase determined by micro-area electron diffraction *** and calculation results of the high-resolution images of the Ti_(2)Al_(20)Gd/Al structure show that there is no other compound at the junction between the Ti_(2)Al_(20)Gd phase and Al,and Ti_(2)Al_(20)Gd phase has a great difference in atomic space with the α-Al,which cannot be directly used as heterogeneous ***,after being decomposed in the aluminum melt,the Ti_(2)Al_(20)Gd phase can promote the refinement effect of the *** the Al-Ti-B-Gd master alloy,there are many dispersed Al_(3)Ti particles with a size of less than 1 μm,which can promote the Al-5Ti-B refining effect.

关键词： Al-5Ti-B alloy refiner Al_(3)Ti rare earth Gd Ti_(2)Al_(20)Gd

Peripheral mitochondrial DNA as a neuroinflammatory biomarker for major depressive disorder

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Neural Regeneration Research 2025年第6期20卷 1541-1554页

作者： Jinmei Ye Cong Duan Jiaxin Han Jinrong Chen ning Sun Yuan Li Tifei Yuan Daihui Peng Division of Mood Disorder Shanghai Mental Health CenterShanghai Jiao Tong University School of MedicineShanghaiChina Department of Psychiatry First Hospital of Shanxi Medical UniversityTaiyuanShanxi ProvinceChina Shanghai Key Laboratory of Psychotic Disorders Brain Health InstituteNational Center for Mental DisordersShanghai Mental Health CenterShanghai Jiao Tong University School of MedicineShanghaiChina Co-Innovation Center of Neuroregeneration Nantong UniversityNantongJiangsu ProvinceChina

In the pathogenesis of major depressive disorder, chronic stress-related neuroinflammation hinders favorable prognosis and antidepressant response. Mitochondrial DNA may be an inflammatory trigger, after its release from stress-induced dysfunctional central nervous system mitochondria into peripheral circulation. This evidence supports the potential use of peripheral mitochondrial DNA as a neuroinflammatory biomarker for the diagnosis and treatment of major depressive disorder. Herein, we critically review the neuroinflammation theory in major depressive disorder, providing compelling evidence that mitochondrial DNA release acts as a critical biological substrate, and that it constitutes the neuroinflammatory disease pathway. After its release, mitochondrial DNA can be carried in the exosomes and transported to extracellular spaces in the central nervous system and peripheral circulation. Detectable exosomes render encaged mitochondrial DNA relatively stable. This mitochondrial DNA in peripheral circulation can thus be directly detected in clinical practice. These characteristics illustrate the potential for mitochondrial DNA to serve as an innovative clinical biomarker and molecular treatment target for major depressive disorder. This review also highlights the future potential value of clinical applications combining mitochondrial DNA with a panel of other biomarkers, to improve diagnostic precision in major depressive disorder.

关键词： biomarker cytokine exosomes inflammasome major depressive disorder microglia mitochondrial DNA mitochondrial dysfunction neuroinflammation Toll-like receptor

KINETICS OF INTERACTION BETWEEN Cu_2S AND Cu_2O IN SOLID STATE UNDER NONISOTHERMAL CONDITION

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中国有色金属学会会刊：英文版 1997年第1期7卷 39-42,51页

作者： song, ning Liu, Chunpeng Kunming Univ of Science & Technology Kunming China

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关键词： kinetics of interaction nonisothermal process Cu 2S Cu 2O