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Recombinant human thrombopoietin in alleviating endothelial cell injury in sepsis

Journal of Intensive Medicine 2024年第3期4卷 384-392页

作者： yun Xie hui Lv Daonan Chen Peijie Huang Shaohong Wu Hongchao Shi Qi Zhao Ruilan Wang Department of Critical Care Medicine Shanghai General HospitalShanghai Jiao Tong University School of MedicineShanghaiChina

Background To evaluate the effect of recombinant human thrombopoietin(rhTPO)on clinical prognosis by exploring changes in endothelial cell injury markers and inflammatory factors in patients with sepsis after treatment with *** This retrospective observational study involved patients with sepsis(diagnosed according to Sepsis 3.0)admitted to Shanghai General Hospital intensive care unit from January 1,2019 to December 31,*** were divided into two groups(control and rhTPO)according to whether they received *** information,clinical data,prognosis,and survival status of the patients,as well as inflammatory factors and immune function indicators were *** main monitoring indicators were endothelial cell-specific molecule(ESM-1),human heparin-binding protein(HBP),and CD31;secondary monitoring indicators were interleukin(IL)-6,tumor necrosis factor(TNF)-α,extravascular lung water index,platelet,antithrombin III,fibrinogen,and international normalized *** used intraperitoneal injection of lipopolysaccharide(LPS)to establish a mouse model of *** were randomly divided into four groups:normal saline,LPS,LPS+rhTPO,and LPS+rhTPO+*** indicators in mice were measured by enzyme-linked immunosorbent *** A total of 84 patients were included in the *** 7 days of treatment,ESM-1 decreased more significantly in the rhTPO group than in the control group compared with day 1(median=38.6[interquartile range,IQR:7.2 to 67.8]pg/mL ***=23.0[IQR:−15.7 to 51.5]pg/mL,P=0.008).HBP and CD31 also decreased significantly in the rhTPO group compared with the control group(median=59.6[IQR:−1.9 to 91.9]pg/mL ***=2.4[IQR:−23.2 to 43.2]pg/mL;median=2.4[IQR:0.4 to 3.5]pg/mL ***=−0.6[IQR:−2.2 to 0.8]pg/mL,P<0.001).Inflammatory markers IL-6 and TNF-αdecreased more significantly in the rhTPO group than in the control group compared with day 1(median=46.0[IQR:15.8 to 99.1]pg/mL ***=31.2[IQR:19.7 to 171.0]

关键词： Thrombopoietin Sepsis Endothelial cells

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Long-term variation of Arctic Sudden Stratospheric Warmings(SSW) and potential causes

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Earth and Planetary Physics 2024年第5期8卷 742-752页

作者： QingRan Li ShaoDong Zhang KaiMing Huang ChunMing Huang yun gong WenTao Tang Zheng Ma School of Electronic Information Wuhan University Guizhou Normal University Key Laboratory of Geospace Environment and Geodesy Ministry of Education State Key Laboratory of Information Engineering in Surveying Mapping and Remote Sensing School of Electronic Information Engineering Jingchu University of Technology

Utilizing the European Centre for Medium-Range Weather Forecast(ECMWF) Reanalysis v5(ERA5), for the first time, we have confirmed close links among Sudden Stratospheric Warmings(SSWs) in the Northern Hemisphere(NH), the polar vortices, and stratospheric Planetary Waves(PWs) by analyzing and comparing their trends. Interestingly, within overall increasing trends, the duration and strength of SSWs exhibit increasing and decreasing trends before and after the winter of 2002, respectively. To reveal possible physical mechanisms driving these trends, we analyzed the long-term trends of the winter(from December to February) polar vortices and of stratospheric PWs with zonal wave number 1. Notably, our results show that in all three time periods(the entire period of 41winters, 1980 to 2020, and the two subperiods — 1980-2002 and 2002-2020) enhancing SSWs were always accompanied by weakening winter polar vortices and strengthening polar PWs like Stationary Planetary Waves(SPWs) and 16-day waves, and vice versa. This is the first proof, based on ERA5 long-term trend data, that weakening polar vortices and enhancing stratospheric PWs(especially SPWs) could cause an increase in SSWs.

关键词： sudden stratospheric warmings stationary planetary waves 16-day waves polar vortrices long-term trend correlation coefficient

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Overstory functional groups indicate the legacy of land use in a secondary tropical forest in southwestern China

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JOURNAL OF FORESTRY RESEARCH 2024年第1期35卷 1-15页

作者： Deng, yun Zhang, Wenfu Cao, Min Dong, Jinlong Chen, hui Deng, Xiaobao Liu, Jiajia Song, Xiaoyang Xia, Shangwen Sha, Liqing Yuan, Shengdong Lin, Luxiang Chinese Acad Sci CAS Key Lab Trop Forest Ecol Xishuangbanna Trop Bot Garden Mengla 666303 Peoples R China Chinese Acad Sci Ctr Plant Ecol Core Bot Gardens Mengla 666303 Peoples R China Chinese Acad Sci Natl Forest Ecosyst Res Stn Xishuangbanna Xishuangbanna Trop Bot Garden Mengla 666303 Peoples R China Univ Chinese Acad Sci Dept Life Sci Beijing 100049 Peoples R China Fudan Univ Dept Life Sci Shanghai 570228 Peoples R China

Anthropogenic disturbances are widespread in tropical forests and influence the species composition in the overstory. However, the impacts of historical disturbance on tropical forest overstory recovery are unclear due to a lack of disturbance data, and previous studies have focused on understory species. In this study, the purpose was to determine the influence of historical disturbance on the diversity, composition and regeneration of overstory species in present forests. In the 20-ha Xishuangbanna tropical seasonal rainforest dynamics plot in southwestern China, the historical disturbance boundaries were delineated based on panchromatic photographs from 1965. Factors that drove species clustering in the overstory layer (DBH >= 40 cm) were analyzed and the abundance, richness and composition of these species were compared among different tree groups based on multiple regression tree analysis. The coefficient of variation of the brightness value in historical panchromatic photographs from 1965 was the primary driver of species clustering in the overstory layer. The abundance and richness of overstory species throughout the regeneration process were similar, but species composition was always different. Although the proportion of large-seeded and vigorous-sprouting species showed no significant difference between disturbed and undisturbed forests in the treelet layer (DBH < 20 cm), the difference became significant when DBH increased. The findings highlight that historical disturbances have strong legacy effects on functional group composition in the overstory and the recovery of overstory species was multidimensional. Functional group composition can better indicate the dynamics of overstory species replacement during secondary succession.

关键词： Historical disturbance Legacy effects Secondary forests Overstory species Functional groups RAIN-FOREST MULTIVARIATE ANALYSES SEED SIZE VEGETATION TREES XISHUANGBANNA REGENERATION DISTURBANCE RECOVERY yunNAN

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A Retrospective Investigation of a Case of Dual Infection by Avian-Origin Influenza A(H10N5)and Seasonal Influenza A(H3N2)Viruses-Anhui Province,China,December 2023-January 2024

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China CDC weekly 2024年第25期6卷 605-613页

作者： Jun He Lei gong Xiaolong Chen Deman Cheng Sai Hou Mengyao Kong Xun Wei Junling Yu Qian Zhu Weiwei Li Wanhang Lu Yujie Feng Hongya Gui Weixi Fang Peng Wang Yidan Xia Yong Sun Wanrong Luo yun Yang Guowei Shen hui Wang Jiabing Wu Anhui Provincial Center for Disease Control and Prevention Hefei CityAnhui ProvinceChina School of Public Health Bengbu Medical UniversityBengbu CityAnhui ProvinceChina Public Health Research Institute of Anhui Province Hefei CityAnhui ProvinceChina School of Public Health Anhui Medical UniversityHefei CityAnhui ProvinceChina Xuancheng City Center for Disease Control and Prevention Xuancheng CityAnhui ProvinceChina Guangde City Center for Disease Control and Prevention Guangde CityAnhui ProvinceChina

Summary What is known about this topic?H10 avian influenza viruses circulate in wild birds and can reassort with other subtypes.H10N8 and H10N3 have previously caused sporadic human infections in *** is added by this report?This report documents the first human case of coinfection with avian-origin H10N5 and seasonal H3N2 influenza *** investigations identified H10N5 in environmental samples linked to the patient,but no transmission to close contacts *** are the implications for public health practice?Enhanced surveillance of avian influenza in live poultry markets and poultry populations is crucial for thoroughly characterizing the epidemiology,transmission,and pathogenesis of H10N5 *** assessments of outbreak control measures is essential to guide effective management.

关键词： poultry Anhui thoroughly

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The difference of the ionomer–catalyst interfaces for poly(aryl piperidinium)hydroxide exchange membrane fuel cells and proton exchange membrane fuel cells

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Nano Research 2024年第7期17卷 6102-6110页

作者： Xuerui Liu Xingdong Wang Chanyu Zhang yun Cai Bowen Chen Dongyue Xin Xiaoxiao Jin Wei Zhu Klaus Wippermann hui Li Ruiyu Li Zhongbin Zhuang Beijing Advanced Innovation Center for Soft Matter Science and Engineering Beijing University of Chemical TechnologyBeijing 100029China State Key Lab of Organic-Inorganic Composites Beijing University of Chemical TechnologyBeijing 100029China Research Institute of Petroleum Processing SINOPECBeijing 100083China DeepHytec Co. Ltd.Shenzhen 518118China Institute of Energy and Climate Research(IEK-14) Forschungszentrum Jülich GmbHJülich 52425Germany Beijing Key Laboratory of Energy Environmental Catalysis Beijing University of Chemical TechnologyBeijing 100029China

The microstructures of the ionomer–catalyst interfaces in the catalyst layers are important for the fuel cell performance because they determine the distribution of the active triple-phase ***,we investigate the ionomer–catalyst interactions in hydroxide exchange membrane fuel cells(HEMFCs)using poly(aryl piperidinium)and compare them with proton exchange membrane fuel cells(PEMFCs).It is found that different catalyst layer microstructures are between the two types of fuel *** ionomer/carbon(I/C)ratio does not have a remarkable impact on the HEMFC performance,while it has a strong impact on the PEMFC performance,indicating the weaker interaction between the HEMFC ionomer and *** dynamics simulations demonstrate that the HEMFC ionomer tends to distribute on the carbon support,unlike the PEMFC ionomer,which heavily covers the Pt *** results suggest that the poisoning effect of the ionomer on the catalyst is much weaker in HEMFCs,and the improved ionomer/catalyst interaction is beneficial for the HEMFC performances.

关键词： hydroxide exchange membrane fuel cells catalysts ionomer oxygen reduction reaction interfaces

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Vertical two-dimensional WS_(2)flakes grown on flexible CNT film for excellent electrochemical performance

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Rare Metals 2024年第1期43卷 164-174页

作者： Qian gong Jing-yun Zou Ming Ren Si-Qi Zhu Yu-Rong Zhou Li-Ming Zhao Jian Chen Yu-Long Wu Jiang-Tao Di Li-Xing Kang Qing-Wen Li School of Nano-Tech and Nano-Bionics University of Science and Technology of ChinaHefei 230026China Key Laboratory of Multifunctional Nanomaterials and Smart Systems Division of Advanced MaterialsSuzhou Institute of Nano-Tech and Nano-BionicsChinese Academy of SciencesSuzhou 215123China Jiangsu Key Laboratory of Micro and Nano Heat Fluid Flow Technology and Energy Application School of Physical Science and TechnologySuzhou University of Science and TechnologySuzhou 215009China

Soft electrochemical actuators that can generate mechanical motions in response to electrical stimuli can be used as artificial muscles in microscale *** electrode materials are the key component of the electrochemical actuator because they limit the ion diffusion and accumulation processes and thus affect the deformation in fast response-time and potential engineering ***-dimensional materials,such as one-dimensional(1D)CNT and two-dimensional(2D)vertically stood WS_(2),are great electrode due to their good electrochemical stability and high surface-to-volume ratios,but show limited performances when being used on their own in the actuators because of low reconstruction or low conductivity.A combination of 1D CNT and 2D WS_(2)could form a heterojunction with both high electrochemical activity and great mechanical ***,by depositing highly disordered graphene nanosheets(HDGNs)on CNT films and then WS_(2)on the formed low-dimensional nanocarbon film,a hybrid WS_(2)/HDGN/CNT film was synthesized through a multistep CVD *** grown WS_(2)nanosheets were achieved by taking advantage of HDGNs which limits CNTs ***,the volume expansion caused by the transition from WO_(3)to WS-2can force the vertical growth of WS_(2).This hybrid film shows excellent electrochemical properties,such as high specific capacitance and high rate *** actuators based on the WS_(2)/HDGN/CNT films show good actuating performance,including stability and reconfigurability.

关键词： CNT Graphene Vertically growth WS_(2) Electrochemical actuators

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现代北太平洋中层水研究进展综述

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地球科学 2024年第8期49卷 2914-2924页

作者：刘辉宫勋中国地质大学广州南沙地大滨海研究院广东广州511462 中国地质大学生物地质与环境地质国家重点实验室湖北武汉430074 齐鲁工业大学(山东省科学院) 山东省计算中心(国家超级计算济南中心)算力互联网与信息安全教育部重点实验室山东济南250014

北太平洋中层水是北太平洋最大的原生水体,是目前发现的北太平洋表层与底层水发生交换的唯一通道,因此认识北太平洋中层水生成和传输过程是理解北太平洋垂向水交换及其环流结构的必要一环.同时,北太平洋中层水的水体特征和环流结构在“... 详细信息

北太平洋中层水是北太平洋最大的原生水体,是目前发现的北太平洋表层与底层水发生交换的唯一通道,因此认识北太平洋中层水生成和传输过程是理解北太平洋垂向水交换及其环流结构的必要一环.同时,北太平洋中层水的水体特征和环流结构在“海—气—冰”耦合系统内显著影响全球碳循环系统和海洋生态系统,进而可能改变全球气候变暖进程.围绕北太平洋中层水的物理海洋学研究主要从20世纪70年代开始,已有研究多依赖走航断面和站点数据,少部分结合数值模拟方法.本文对已有的北太平洋中层水研究工作进行了综述,进而提出继续深化对北太平洋中层水的研究包括如下几个方面:北太平洋中层环流系统趋势和“季节性—年际—年代际”振荡的特征识别;北太平洋中层环流系统对大气环流和上层海洋过程的响应机制研究;北太平洋中层环流系统稳定性及对气候变暖的反馈机制研究.

关键词：北太平洋中层水中层环流垂向水交换海洋地质

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Tuning interaction strength between CeO_(2) and iridium to promote CO oxidation over Ir/TiO_(2)

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Journal of Rare Earths 2024年第4期42卷 651-659页

作者： Lu Dai Binghua Li Yuhan Peng Xianwei Hao Runquan Xuan Hua Huang Yiming Bi Liping Xu Yanhui Zhang yun Guo Fangqi Du Li Wang hui Wang Technology Center China Tobacco Zhejiang Industrial Co.Ltd.Hangzhou310024China Research Institute of Industrial Catalysis East China University of Science and TechnologyShanghai200237China

The interaction between support and noble metal plays a crucial role in heterogeneous catalysis ***,how to tune metal support interactions to optimize the activity still needs further ***_(2) was introduced to promote CO oxidation ove r Ir/TiO_(2) by adjusting the interaction strength between iridium(Ir)and CeO_(2).The strong interaction between Ir and CeO_(2) blocks CO adsorption and causes low CO oxidation ***,introducing CeO_(2) on Ir/TiO_(2) produces localized interaction between Ir and CeO_(2),which can tune the surface electronic state of Ir,so a"volcano curve"relationship between CO oxidation activity and electronic state is *** amount of CeO_(2) on Ir/TiO_(2)(Ir/Ce_(0.2)Ti)leads to CO complete oxidization at 22℃,and a new pathway for CO oxidation was *** study demonstrates that the utilization of tuning interaction strength between active metal and support is a potential method to increase the catalytic activity.

关键词： CO oxidation CeO_(2) Localized interaction Interaction strength Supported Ir catalysts Rareearths

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科学把握和全面发展邓小平的社会主义本质论

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马克思主义研究 2024年第7期 115-127,156页

作者：龚云中国社会科学院金融研究所党委北京100710 中国社会科学院习近平新时代中国特色社会主义思想研究中心北京100710 中国社会科学院大学马克思主义学院北京100710

邓小平的社会主义本质论具有重大的理论意义和深远的历史意义,需要科学把握和全面发展。邓小平的社会主义本质论,把“解放生产力,发展生产力”作为社会主义的首要本质,把“消灭剥削,消除两极分化”作为社会主义的先进本质,把“最终实现... 详细信息

邓小平的社会主义本质论具有重大的理论意义和深远的历史意义,需要科学把握和全面发展。邓小平的社会主义本质论,把“解放生产力,发展生产力”作为社会主义的首要本质,把“消灭剥削,消除两极分化”作为社会主义的先进本质,把“最终实现共同富裕”作为社会主义的终极本质,环环相扣,层层递进,构成了一个逻辑严密的整体判断,从最深层次回答了什么是社会主义这个根源性问题,是中国共产党探索社会主义的原创性理论成果,发展了科学社会主义基本原理,奠定了邓小平理论的科学基石,推动了世界社会主义发展。党的十八大以来,习近平立足中国特色社会主义新时代,总结世界社会主义500多年历史经验,创造性提出中国共产党领导是中国特色社会主义最本质的特征等重大观点,始终坚持解放和发展生产力,旗帜鲜明反对两极分化,稳步推进全体人民共同富裕,全面坚持和发展了邓小平的社会主义本质论,标志对社会主义的认识、对中国特色社会主义的把握达到了一个前所未有的新高度。

关键词：邓小平习近平社会主义本质

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Demonstration of controlled high-dimensional quantum teleportation

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Science China(Physics,Mechanics & Astronomy) 2024年第3期67卷 1-6页

作者： Min-Yu Lv Xiao-Min Hu Neng-Fei gong Tie-Jun Wang Yu Guo Bi-Heng Liu yun-Feng Huang Chuan-Feng Li Guang-Can Guo CAS Key Laboratory of Quantum Information University of Science and Technology of ChinaHefei 230026China CAS Centerfor Excellence in Quantum Information and Quantum Physics University of Science and Technology of ChinaHefei230026China Hefei National Laboratory University of Science and Technology of ChinaHefei 230088China State Key Laboratory of Information Photonics and Optical Communications School of ScienceBeijing University of Posts and TelecommunicationsBeijing 100876China

Controlled quantum teleportation(CQT), which is regarded as the prelude and backbone for a genuine quantum internet, reveals the cooperation, supervision, and control relationship among the sender, receiver, and controller in the quantum network within the simplest unit. Compared with low-dimensional counterparts, high-dimensional CQT can exhibit larger information transmission capacity and higher superiority of the controller's authority. In this article, we report a proof-of-principle experimental realization of three-dimensional(3D) CQT with a fidelity of 97.4% ± 0.2%. To reduce the complexity of the circuit, we simulate a standard 4-qutrit CQT protocol in a 9×9-dimensional two-photon system with high-quality operations. The corresponding control powers are 48.1% ± 0.2% for teleporting a qutrit and 52.8% ± 0.3% for teleporting a qubit in the experiment, which are both higher than the theoretical value of control power in 2-dimensional CQT protocol(33%). The results fully demonstrate the advantages of high-dimensional multi-partite entangled networks and provide new avenues for constructing complex quantum networks.

关键词： high dimension quantum information quantum teleportation quantum nonlocality

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