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World Journal of Gastrointestinal Oncology 2024年第1期16卷 214-233页

作者： Mao-Xiu Yuan Qi-Gui cai Zhen-Yang Zhang Jian-Zhong Zhou cai-yun Lan Jiang-Bo Lin The Graduate School Fujian Medical UniversityFuzhou 350000Fujian ProvinceChina Department of Thoracic Surgery Affiliated Hospital of Jinggangshan UniversityJi’an 343000Jiangxi ProvinceChina Department of Thoracic Surgery Fujian Medical University Union HospitalFuzhou 350000Fujian ProvinceChina

BACKGROUND The effectiveness of neoadjuvant therapy in esophageal cancer(EC)treatment is still a subject of *** To compare the clinical efficacy and toxic side effects between neoadjuvant chemoradiotherapy(nCRT)and neoadjuvant chemotherapy(nCT)for locally advanced EC(LAEC).METHODS A comprehensive search was conducted using multiple databases,including PubMed,EMBASE,MEDLINE,Science Direct,The Cochrane Library,China National Knowledge Infrastructure,Wanfang Database,Chinese Science and Technology Journal Database,and Chinese Biomedical Literature Database *** up to December 2022 comparing nCRT and nCT in patients with EC were *** The analysis revealed significant differences between nCRT and nCT in terms of disease-free *** results indicated that nCRT provided better outcomes in terms of the 3-year overall survival rate(OSR)[odds ratio(OR)=0.95],complete response rate(OR=3.15),and R0 clearance rate(CR)(OR=2.25).However,nCT demonstrated a better 5-year OSR(OR=1.02)than ***,when compared to nCRT,nCT showed reduced risks of cardiac complications(OR=1.15)and pulmonary complications(OR=1.30).CONCLUSION Overall,both nCRT and nCT were effective in terms of survival outcomes for ***,nCT exhibited better performance in terms of postoperative complications.

关键词： Esophageal cancer Neoadjuvant chemoradiotherapy Radical resection for esophageal cancer Neoadjuvant chemotherapy Meta-analysis

High-resolution neutronics model for ^(238)Pu production in high-flux reactors

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Nuclear Science and Techniques 2024年第5期35卷 226-236页

作者： Qing-Quan Pan Qing-Fei Zhao Lian-Jie Wang Bang-Yang Xia yun cai Jin-Biao Xiong Xiao-Jing Liu School of Nuclear Science and Engineering Shanghai Jiao Tong UniversityShanghai 200240China Science and Technology on Reactor System Design Technology Laboratory Nuclear Power Institute of ChinaChengdu 610200China

We proposed and compared three methods(filter burnup,single energy burnup,and burnup extremum analysis)to build a high-resolution neutronics model for 238Pu production in high-flux *** filter burnup and single energy burnup methods have no theoretical approximation and can achieve a spectrum resolution of up to~1 eV,thereby constructing the importance curve and yield curve of the full energy *** burnup extreme analysis method combines the importance and yield curves to consider the influence of irradiation time on production efficiency,thereby constructing extreme *** three curves,which quantify the transmutation rate of the nuclei in each energy region,are of physical significance because they have similar distributions.A high-resolution neutronics model for ^(238)Pu production was established based on these three curves,and its universality and feasibility were *** neutronics model can guide the neutron spectrum optimization and improve the yield of ^(238)Pu by up to 18.81%.The neutronics model revealed the law of nuclei transmutation in all energy regions with high spectrum resolution,thus providing theoretical support for high-flux reactor design and irradiation production of ^(238)Pu.

关键词： ^(238)Pu Neutronics model High-flux reactor Spectrum resolution Spectrum optimization

Design and fabrication of lightweight AlCrFeNiTix compositionally complex alloys with exceptional specific strength

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Rare Metals 2024年第7期43卷 3314-3328页

作者： Jun-Zhi Li Wei-Zong Bao Jie Chen Bo-Hua Yu Kun Zuo Tian Gao Ze-yun cai Guo-Qiang Xie School of Materials Science and Engineering Harbin Institute of Technology (Shenzhen) State Key Laboratory of Advanced Welding and Joining Harbin Institute of Technology

This study focuses on compositionally complex alloys（CCAs）,aiming to achieve a balance between high strength and low density for new energy and aerospace *** composition of AlCrFeNiTixCCAs is strategically guided by employing density functional theory and the theoretical design of thermodynamic *** CCAs,particularly AlCrFeNiTi0.25alloy,demonstrate remarkable specific yield strength（1640.8 MPa） and 22.7% maximum *** incorporation of Ti facilitates the formation of lightweight and high-strength L21phase,contributing to the overall high specific *** effects of grain boundary strengthening,solid solution strengthening,Orowan strengthening and Peierls flow stress further enhance *** exploration of micros tructural changes during fracture reveals the role of ordered phases in suppressing crack propagation and absorbing energy within disordered phases,thereby improving the toughness and fracture resistance of *** methods and discoveries establish a robust foundation for advancing the development of novel lightweight CCAs.

关键词： Lightweight Compositionally complex alloys Specific yield strength

Diagnostic performance of dynamic contrast-enhanced magnetic resonance imaging parameters and serum tumor markers in rectal carcinoma prognosis

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World Journal of Gastrointestinal Oncology 2024年第5期16卷 1796-1807页

作者： Ren-Qi Mu Jun-Wei Lv cai-yun Ma Xiao-Hui Ma Dong Xing Hou-Sheng Ma Department of Radiology Yantai Mountain HospitalYantai 264001Shandong ProvinceChina Department of Radiology Yantai Yuhuangding HospitalYantai 264000Shandong ProvinceChina Department of Gynaecology Yantai Yuhuangding HospitalYantai 264000Shandong ProvinceChina The First Clinical Medical College Xinjiang Medical UniversityUrumqi 830011Xinjiang Uygur Autonomous RegionChina

BACKGROUND Rectal carcinoma(RC),one of the most common malignancies globally,presents an increasing incidence and mortality year by year,especially among young people,which seriously affects the prognosis and quality of life of *** present,dynamic contrast-enhanced magnetic resonance imaging(DCE-MRI)parameters and serum carbohydrate antigen 19-9(CA19-9)and CA125 Levels have been used in clinical practice to evaluate the T stage and differentiation of ***,the accuracy of these evaluation modalities still needs further *** study explores the application and value of these methods in evaluating the T stage and differentiation degree of *** To analyze the diagnostic performance of DCE-MRI parameters combined with serum tumor markers(TMs)in assessing pathological processes and prognosis of RC *** A retrospective analysis was performed on 104 RC patients treated at Yantai Yuhuangding Hospital from May 2018 to January *** were categorized into stages T1,T2,T3,and T4,depending on their T stage and differentiation *** addition,they were assigned to low(L group)and moderate-high differentiation(M+H group)groups based on their differentiation *** levels of DCE-MRI parameters and serum CA19-9 and CA125 in different groups of patients were *** addition,the value of DCE-MRI parameters[volume transfer constant(Ktrans),rate constant(Kep),and extravascular extracellular volume fraction(Ve)in assessing the differentiation and T staging of RC patients was ***,the usefulness of DCE-MRI parameters combined with serum CA19-9 and CA125 Levels in the evaluation of RC differentiation and T staging was *** Ktrans,Ve,CA19-9 and CA125 were higher in the high-stage group and L group than in the low-stage group and M+H Group,respectively(P<0.05).The areas under the curve(AUCs)of the Ktran and Ve parameters were 0.638 and 0.694 in the diagnosis of high and low stages,respectively,and 0.672 and 0

关键词： Rectal carcinoma Volume transfer constant Rate constant Extravascular extracellular volume fraction Serum carbohydrate antigen 19-9 Serum carbohydrate antigen 125

The difference of the ionomer–catalyst interfaces for poly(aryl piperidinium)hydroxide exchange membrane fuel cells and proton exchange membrane fuel cells

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Nano Research 2024年第7期17卷 6102-6110页

作者： Xuerui Liu Xingdong Wang Chanyu Zhang yun cai Bowen Chen Dongyue Xin Xiaoxiao Jin Wei Zhu Klaus Wippermann Hui Li Ruiyu Li Zhongbin Zhuang Beijing Advanced Innovation Center for Soft Matter Science and Engineering Beijing University of Chemical TechnologyBeijing 100029China State Key Lab of Organic-Inorganic Composites Beijing University of Chemical TechnologyBeijing 100029China Research Institute of Petroleum Processing SINOPECBeijing 100083China DeepHytec Co. Ltd.Shenzhen 518118China Institute of Energy and Climate Research(IEK-14) Forschungszentrum Jülich GmbHJülich 52425Germany Beijing Key Laboratory of Energy Environmental Catalysis Beijing University of Chemical TechnologyBeijing 100029China

The microstructures of the ionomer–catalyst interfaces in the catalyst layers are important for the fuel cell performance because they determine the distribution of the active triple-phase ***,we investigate the ionomer–catalyst interactions in hydroxide exchange membrane fuel cells(HEMFCs)using poly(aryl piperidinium)and compare them with proton exchange membrane fuel cells(PEMFCs).It is found that different catalyst layer microstructures are between the two types of fuel *** ionomer/carbon(I/C)ratio does not have a remarkable impact on the HEMFC performance,while it has a strong impact on the PEMFC performance,indicating the weaker interaction between the HEMFC ionomer and *** dynamics simulations demonstrate that the HEMFC ionomer tends to distribute on the carbon support,unlike the PEMFC ionomer,which heavily covers the Pt *** results suggest that the poisoning effect of the ionomer on the catalyst is much weaker in HEMFCs,and the improved ionomer/catalyst interaction is beneficial for the HEMFC performances.

关键词： hydroxide exchange membrane fuel cells catalysts ionomer oxygen reduction reaction interfaces

残障服务的供需困境及其破解策略——基于制度逻辑的视角

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吉林大学社会科学学报 2024年第3期64卷 101-115,237页

作者：亓彩云山东大学哲学与社会发展学院济南250100

我国“完善残疾人关爱服务体系”的工作成果显著,但始终未达到供需匹配的理想状态。既有研究多关注于资源环境和技术环境以及单一规制性要素的不足,忽视了复杂制度系统中不同制度要素及其结合的力量。基于实地调研,文章以新制度主义的... 详细信息

我国“完善残疾人关爱服务体系”的工作成果显著,但始终未达到供需匹配的理想状态。既有研究多关注于资源环境和技术环境以及单一规制性要素的不足,忽视了复杂制度系统中不同制度要素及其结合的力量。基于实地调研,文章以新制度主义的相关理论为切入点,从制度要素冲突与行动脱耦两方面对残障服务供需困境产生的原因进行深入研究。研究发现,规制性制度要素、规范性制度要素与文化-认知性制度要素的一致性是保证残障服务场域有效运转的前提。实践中,政府强有力的规制性要素提供了充分的合法性支持并统领着制度运行,但规范性要素内部行政逻辑、市场逻辑和助残社会规范的矛盾,文化-认知性要素内部消极残障观和积极残障观的矛盾以及两者与规制性要素的冲突,构成了残障服务供需困境的内在基础。面对要素内部及要素间的冲突,行动者采取脱耦行动策略,导致服务供需的矛盾。残障服务供需困境的破解策略包括:形成助残社会规范,建立积极的残障认知,改革规制性运作逻辑,以实现要素内部统一与要素间的耦合。

关键词：残障服务供需困境制度要素冲突行动脱耦

关于20世纪80年代中国马克思主义史学理论重建的反思

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湖北大学学报（哲学社会科学版） 2024年第2期51卷 57-67页

作者：董彩云山东大学儒学高等研究院山东济南250100

20世纪80年代围绕中国马克思主义史学理论重建的讨论是史学界的一次重要学术争鸣。这场讨论是在改革开放新的历史背景下,史学界为厘清中国马克思主义史学理论资源和实践上的得失、确立新的历史时期马克思主义对中国史学发展的指导进行... 详细信息

20世纪80年代围绕中国马克思主义史学理论重建的讨论是史学界的一次重要学术争鸣。这场讨论是在改革开放新的历史背景下,史学界为厘清中国马克思主义史学理论资源和实践上的得失、确立新的历史时期马克思主义对中国史学发展的指导进行的努力,对改革开放以后中国史学发展具有重要影响。站在今天的角度反思,这场学术争鸣在当时有其不可或缺的创获,譬如历史发展动力和历史创造者问题的讨论挑战了阶级斗争史观的唯一性,史学的社会功能和学术价值得到更全面理性的认识等。但讨论对唯物史观所做的正本清源工作不够彻底,意识形态因素与思想解放程度对史学方法探讨有所制约等时代局限,表明中国马克思主义史学理论重建工作尚未完成。从20世纪中国马克思主义史学发展历程来看,80年代中国马克思主义史学反思、打击了极端意识形态化,推动了新时期马克思主义史学重获新生、恢复学术活力,其历史价值不容抹杀,但对此前唯物史观与中国实际相结合的历史遗产未能较好吸收。未来中国化的马克思主义历史学研究的确立,要坚持把马克思主义基本原理同中国具体实际相结合,同中华优秀传统文化相结合,构建基于中国本土经验的历史理论体系。

关键词：马克思主义史学 20世纪80年代史学马克思主义史学理论唯物史观

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树突状细胞在多发性硬化免疫治疗中的应用

中国现代神经疾病杂志 2024年第5期24卷 320-330页

作者：刘彩云金涛吉林大学第一医院神经内科与神经科学中心长春130021

树突状细胞是机体功能最强的专职抗原呈递细胞,基于其亚型和环境信号在诱导炎症或耐受性免疫反应中起关键作用。树突状细胞对于多发性硬化的发生和疾病进展至关重要。在多发性硬化动物模型和早期临床试验中,诱导耐受性树突状细胞具有强... 详细信息

树突状细胞是机体功能最强的专职抗原呈递细胞,基于其亚型和环境信号在诱导炎症或耐受性免疫反应中起关键作用。树突状细胞对于多发性硬化的发生和疾病进展至关重要。在多发性硬化动物模型和早期临床试验中,诱导耐受性树突状细胞具有强大的治疗潜力。与体外诱导耐受性树突状细胞相比,特异性靶向其表面受体的体内诱导策略表现出更大的前景和优势。本文总结树突状细胞在调节免疫耐受和多发性硬化发生和进展中的作用,并对有潜力作为靶点的树突状细胞表面特异性受体进行梳理,以为耐受性免疫治疗多发性硬化提供新的靶点和策略。

关键词：树突状细胞(非MeSH词) 多发性硬化免疫疗法综述

我国研究型高校如何高质量开展有组织科研——以华中科技大学为例

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研究与发展管理 2024年第3期36卷 175-180页

作者：龙志刘采云华中科技大学科学技术发展院武汉430074

高校有组织科研,是对国家战略导向与市场需求的有机整合,是新战略机遇时期对高校科研模式提出的新要求。本文分析了研究型高校有组织科研的现状,并以华中科技大学为例,论述了学校在有组织科研方面采取的实践举措及积极成效。面对当前全... 详细信息

高校有组织科研,是对国家战略导向与市场需求的有机整合,是新战略机遇时期对高校科研模式提出的新要求。本文分析了研究型高校有组织科研的现状,并以华中科技大学为例,论述了学校在有组织科研方面采取的实践举措及积极成效。面对当前全球科技领域的战略博弈,我国研究型高校要围绕国家战略需求,进一步发挥科研优势,持续提升有组织科研的战略能力。

关键词：有组织科研战略导向研究型大学

论历史长篇小说《占布拉道尔吉》的非虚构写作

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内蒙古民族大学学报（哲学社会科学蒙古文版） 2024年第1期 52-60页

作者：彩云不详