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Duality theorem for weak L-R smash products

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Applied Mathematics(A Journal of Chinese Universities) 2010年第4期25卷 481-488页

作者： ZHOU Xiao-yan LI Qiang ZHANG liang-yun Department of Mathematics, Nanjing Agricultural University, Nanjing 210095, China Department of Mathematics Nanjing Agricultural University Nanjing China

This paper gives a duality theorem for weak L-R smash products, which extends the duality theorem for weak smash products given by Nikshych.

关键词： Weak Hopf algebras weak L-R smash products duality theorem.

Extracellular vesicles in neurodegenerative diseases: Insights and new perspectives

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Genes & Diseases 2021年第2期8卷 124-132页

作者： Qian Yuan Xiao-dong Li Si-miao Zhang Hong-wei Wang yun-liang Wang Department of Neurology The Second Affiliated Hospital of Zhengzhou UniversityZhengzhouHenan Province450014PR China Department of Neurology Zhengzhou Central HospitalZhengzhouHenan Province450014PR China Department of Medicine The University of ChicagoIL60637USA Department of Neurology The 960th Hospital of Chinese PLAZiboShandong Province255300PR China

Extracellular vesicles(EVs)are vesicle-like substances released by eukaryotic *** on their origin and size,EVs are mainly divided into exosomes,microvesicles and apoptotic bodies,and they are secreted by eukaryotic cells under physiological and pathological *** are enriched with nucleic acids,proteins and other *** can regulate the function of adjacent and distant cells,and they are even involved in the pathogenesis of *** contain proteins associated with the pathogenesis of neurodegenerative diseases(NDs),such as the a-synuclein(a-syn)and tau proteins,which suggest potential roles for EVs as biomarkers and carriers of drugs and other therapeutic molecules that can cross the bloodebrain barrier to treat *** this review,we summarized the function of EVs in the pathogenesis of different NDs and related advances in EVs as diagnostic biomarkers and treatments for diseases.

关键词： Biomarker Exosomes Extracellular vesicles Neurodegenerative diseases

Block copolymer assisted topochemical polymerization:A facile and efficient route to robust polymeric nanoporous membranes decorated with versatile amino acids

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Chinese Chemical Letters 2020年第3期31卷 885-889页

作者： yun liang Wanyue Ouyang Peng Wang Wanlin Zhang Shiqiang Wang Li Tian Yong Ju Guangtao Li Key Lab of Organic Optoelectronics and Molecular Engineering Department of ChemistryTsinghua UniversityBeijing 100084China

Based on block copolymer assisted topochemical polymerization,a new strategy for facilely producing robust nanoporous membranes with controlled incorporation of functional groups onto nanopores is *** exemplified by preparing nanoporous polypyrrole decorated with amino acids,this strategy exhibits a high degree of freedom for tailoring the surface functionality in the created pores.

关键词： Block copolymer Supramolecular ensemble Topochemical polymerization Nanoporous membranes Pore functionalization

Effects of casein glycomacropeptide on the early development of primary colorectal cancer in rats

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Food Science and Human Wellness 2013年第3期2卷 113-118页

作者： Qingsen Chen yun liang Chenchen Zhu Yali Yan Guangchang Pang Tianjin Key Laboratory of Food Biotechnology College of Biotechnology and Food ScienceTianjin University of CommerceTianjin 300134China

In this paper,we utilized dimethylhydrazine(DMH)-induced colorectal cancer(CC)model rats to explore the effects of casein glycomacropeptide(CGMP)on colorectal *** with CC were orally administrated with 10,50,or 100 mg/kg bw d CGMP,or the same volume of phosphatebuffered saline for 15 *** total numbers of aberrant crypt foci(ACF)and crypts per focus in colon were scored using a light microscope at low magnification after the colon was stained with methylene blue *** methylation level of DNA extracted from colon was detected using methylation-specific *** expression of p16 and mucin 2(MUC2)proteins were measured by *** results showed that although ACF were found in rats treated with CGMP,their number was significantly decreased compared to that of model *** addition,methylation and expression levels of p16 and MUC2 were also inhibited by CGMP,which were more obvious in rats treated with 50 mg/kg bw d *** conclusion,CGMP has potential application as nutritional therapy for preventing colorectal cancer.©2013 Beijing Academy of Food *** and hosting by Elsevier *** rights reserved.

关键词： Casein glycomacropeptide Colorectal cancer DNA methylation p16 Mucin 2

2D-ball simulations on stiffness influences for coal bump

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Journal of Coal Science & Engineering(China) 2009年第2期15卷 161-165页

作者： TAN yun-liang SUN Chun-jiang ZHANG Zhen-yu Key Lab of Mine Disaster Prevention and Control Shandong University of Science and Technology Qingdao 266510 China Xinwen Mining Cooperation Ltd. Tai＇an 271000 China

Coal bump is a dynamic process,thus it is necessary to reveal the process validly.2D-ball code is an efficient approach developed by the authors based on the basicDEM rationale proposed by *** simulations show that the coal bump experiencesa process of energy accumulation,sudden release of energy and energy *** stiffness of coal particles has a great influence on the coal bump morphosisand particle ***,the larger the stiffness of particles,the longer the shootingoff period and the larger the bump *** is in agreement with the results of laboratoryexperiment and in-situ ***,the stiffness of particles has an influence onthe quantity value energy and no influence on the releasing energy pattern of the coalbump.

关键词： 2D-ball code coal bump stiffness of particle simulation

Study on the formation mechanism of shock wave in process of coal and gas outburst

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Journal of Coal Science & Engineering(China) 2009年第2期15卷 134-137页

作者： SUN Dong-ling MIAO Fa-tian liang yun-pei College of Resource and Environment Engineering Shandong University of Science and Technology Qingdao 266510China Chongqing Research Institute China Coal Research Institute Chongqing 400037 China

According to the research results of motion parameters of coal-gas flow,analyzedthe formation mechanism of shock waves at different states of coal-gas flow in theprocess of coal and gas outburst,and briefly described the two possible cases of outburstshock wave formation and their formation conditions in the process of coal and gas out-burst,and then pointed out that a high degree of under-expanded coal-gas flow was themain reason for the formation of a highly destructive shock *** research resultsimproved the shock wave theory in coal and gas outburst.

关键词： coal and gas outburst coal-gas flow outlet pressure shock wave

Coal damage mechanism in the developing process of coal and gas outburst

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Journal of Coal Science & Engineering(China) 2009年第2期15卷 138-142页

作者： JIN Hong-wei HU Qian-ting liang yun-pei Chongqing Research Institute China Coal Research Institute Chongqing 400037 China

Based on the damage analysis of elliptical aperture,the mechanism of coal damagein the developing process of coal and gas outburst was *** results show thatthe damage to coal by gas is mainly caused by the concentrated tensile stress appearing nearthe endpoint of the *** in coal,gas pressure,ground stress and the tensilestrength of the coal matrix are the major controlling factors of this kind of *** theground stress releases abruptly and the gas pressure is high,tensile failure will occur aroundthe endpoint of the small pores due to gas pressure,and the coal may be broken up like powder;this is called ***,when the gas pressure is low,the tensile stress canonly occur around the endpoint of the large pores and fractures due to gas pressure,the fracturesin coal extend and link together,the fracture extension direction is statistically perpendicularto the direction of the minor principal *** kind of damage is shown as the stratifiedspall around the outburst hole.

关键词： coal and gas outburst development coal damage fracture extend

Design, synthesis and antibacterial activity of novel pleuromutilin derivatives with 4H-pyran-4-one and pyridin-4-one substitution in the C-14 side chain

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Chinese Chemical Letters 2016年第2期27卷 235-240页

作者： Chen-Yu Ling yun-liang Tao Wen-Jing Chu Hui Wang Hai-Dong Wang Yu-She Yang State Key Laboratory of Drug Research Shanghai Institute of Materia Medica Chinese Academy of Sciences School of Petrochemical Engineering Changzhou University Department of Microbiology China Pharmaceutical University

A series of novel pleuromutilin derivatives with 4H-pyran-4-one and pyridin-4-one substitution in the C-14 side chain have been designed and synthesized. In vitro antibacterial activity evaluation showed that most of the derivatives exhibited potent antibacterial activity against drug resistant Gram-positive strains. Compounds 12 a, 12 d, and 28 are the most active derivatives in this series, displaying activity comparable to that of retapamulin and BC-3781. As the metabolic stability of this series is not satisfactory, further modifications are going on to improve their pharmacokinetic profile.

关键词： Multi-drug resistant bacteria Pleuromutilin 4H-Pyran-4-one Antibacterial activity

Tunable catalytic activity of gadolinium-doped ceria nanoparticles for pro-oxidation of hydrogen peroxide

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Nano Research 2020年第9期13卷 2384-2392页

作者： Anuja Bhalkikar Tai-Sing Wu Tamra J.Fisher Anandakumar Sarella Dawei Zhang Yi Gao yun-liang Soo Chin Li Cheung Department of Chemistry University of Nebraska-LincolnLincolnNE 68588USA Department of Physics "National Tsing Hua University"Hsinchu 30013TaiwanChina Nebraska Center for Materials and Nanoscience University of Nebraska-LincolnLincolnNEB 68588USA Shanghai Institute of Applied Physics Chinese Academy of SciencesShanghai 201800China "National Synchrotron Radiation Research Centre" Hsinchu 30076TaiwanChina

We report a study of the roles of gadolinium(lll)(Gd3+)dopants in influencing the catalytic activity of gadolinium-doped ceria nanoparticles towards the pro-oxidation of hydrogen peroxide to hydroxyl *** doped ceria nanoparticles with dopant concentrations of 0.6 wt.%,3 wt.%,and 6 wt.%Gd^3+were synthesized using an ozone-mediated method for tuning their catalytic *** Gd dopants were found to foster an increase in the percentage of Ce^3+ions in the doped ceria *** reaction kinetic study revealed that the relationship between the overall reaction rates and the Gd dopant concentrations in our doped materials followed a volcano-like *** contrast,the apparent activation energy values of these Gd-doped ceria nanoparticles were found to be positively associated with the concentrations of Gd *** overall catalytic activity trend was attributed to the interplay between the promotion and degradation effects of the Gd dopants on the properties of doped ceria nanoparticles.

关键词： ceria cerium oxide gadolinium pro-oxidation hydrogen peroxide hydroxyl radicals ozone