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Robust Fingerprint Construction Based on Multiple Path Loss Model (M-PLM) for Indoor Localization

Computers, Materials & Continua 2023年第1期74卷 1801-1818页

作者： yun fen yong Chee Keong Tan Ian Kim Teck Tan Su Wei Tan School of Information Technology Monash University MalaysiaSubang JayaSelangorMalaysia School of Mathematical and Computer Sciences Heriot-Watt University MalaysiaWilayah Persekutuan PutrajayaMalaysia

A robust radio map is essential in implementing a fingerprint-based indoor positioning system(IPS).However,the offline site survey to manually construct the radio map is time-consuming and *** interpolation techniques have been proposed to infer the virtual fingerprints to reduce the time and effort required for offline site *** paper presents a novel fingerprint interpolator using a multi-path loss model(MPLM)to create the virtual fingerprints from the collected sample data based on different signal paths from different access points(APs).Based on the historical signal data,the poor signal paths are identified using their standard *** proposed method reduces the positioning errors by smoothing out the wireless signal fluctuations and stabilizing the signals for those poor signal *** consideringmultipath signal propagations from different APs,the inherent noise from these signal paths can be ***,locations of the signal data with standard deviations higher than the threshold are *** new fingerprints are then generated at these locations based on the proposed M-PLM interpolation function to replace the old *** proposed technique interpolates virtual fingerprints based on good signal paths with more stable signals to improve the positioning *** results show that the proposed scheme enhances the positioning accuracy by up to 44%compared to the conventional interpolation techniques such as the Inverse DistanceWeighting,Kriging,and single Path *** a result,we can overcome the site survey problems for IPS by building an accurate radio map with more reliable signals to improve indoor positioning performance.

关键词： Path loss model radio map indoor positioning system interpolation fingerprinting

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Trinuclear gold-catalyzed site-selective alkylation of peptides

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Science China Chemistry 2025年第1期68卷 249-256页

作者： Qing-yun Fang Chengyihan Gu Yinghan Chen Wencheng Yan yong Liang Weipeng Li Chengjian Zhu Jie Han Jin Xie State Key Laboratory of Coordination Chemistry Jiangsu Key Laboratory of Advanced Organic Materials Chemistry and Biomedicine Innovation Center (Chem BIC) School of Chemistry and Chemical Engineering Nanjing University Green Catalysis Center College of Chemistry Zhengzhou University State Key Laboratory of Natural Medicines China Pharmaceutical University

Selective modification of peptides has always been a challenging issue. The selective alkylation of peptides can alter the biological activity and physical properties of molecules, and it has gained significant research interest. We herein disclose an intriguing gold-catalyzed alkylation of peptides using bench-stable unactivated alkyl bromides under photoredox catalysis. A wide range of structurally diverse primary, secondary and tertiary alkyl bromides serve as effective coupling partners to precisely connect with the α-C(sp3)–H in glycine residue of peptides. This protocol demonstrates an exceptionally broad scope for alkyl halides and excellent tolerance for a wide range of useful functional groups. A series of relay transformations to construct cyclic peptides, to proceed click reaction and to realize peptide fluorescence labeling further enhance its synthetic practicality. In addition, mechanistic studies and density functional theory(DFT) calculations reveal an inner-sphere and subsequent outersphere single electron transfer(SET) mechanism.

关键词： gold catalysis peptide alkylation C-C coupling radical

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关联理论视域下古典名著单元整体教学路径探微

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教学与管理 2025年第2期 47-50页

作者：万云峰杨永江苏省徐州市铜山区特殊教育中心江苏徐州221116 江苏省徐州市铜山区教师发展中心江苏徐州221116

关联理论是一种认知语用学理论,对古典名著单元教学具有指导意义。针对教材解读和教学实践中存在的“失联”现象,古典名著单元教学可以通过认知关联、学用关联和循证关联架构单元教学内容,进阶设计单元教学策略,推进课内外阅读,从而建... 详细信息

关联理论是一种认知语用学理论,对古典名著单元教学具有指导意义。针对教材解读和教学实践中存在的“失联”现象,古典名著单元教学可以通过认知关联、学用关联和循证关联架构单元教学内容,进阶设计单元教学策略,推进课内外阅读,从而建构精读、略读、课外阅读三位一体的教学样态,提升学生语文综合素养。

关键词：关联理论古典名著单元整体教学

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复式钢管混凝土墩柱轴压性能及承载力提高分析

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工程力学 2025年第1期42卷 209-222页

作者：张玉芬郝圣旺李栋磊方永坚燕山大学建筑工程与力学学院秦皇岛066099 河北工业大学土木与交通学院天津300401 河北省土木工程绿色建造与智能运维重点实验室秦皇岛066099

为提升矩形钢管混凝土独柱墩的工作性能，在其截面内套异心双圆钢管形成新型复式钢管混凝土墩柱。该文进行了7个墩柱轴压荷载试验，通过对比空钢管柱、矩形墩柱和夹层墩柱分析了新型墩柱的破坏形态、钢管应变发展及承载力和延性差异，... 详细信息

为提升矩形钢管混凝土独柱墩的工作性能，在其截面内套异心双圆钢管形成新型复式钢管混凝土墩柱。该文进行了7个墩柱轴压荷载试验，通过对比空钢管柱、矩形墩柱和夹层墩柱分析了新型墩柱的破坏形态、钢管应变发展及承载力和延性差异，最后利用钢管和混凝土的组合效应原理进行组合墩柱轴压承载力提高分析。研究得出新型复式钢管混凝土墩柱轴压破坏形态为鼓曲破坏，其极限承载力较夹层墩柱提高20%，较矩形墩柱提高22%，延性提高效果更为明显;新型墩柱内、外钢管应变发展充分，说明钢管较好地发挥了竖向承载和横向约束混凝土的能力;根据钢板的正则化宽厚比和屈曲后强度计算得出，内、外钢管在混凝土的支撑下承载力提高15%，混凝土在钢管的约束下承载力提高49%;根据约束组合效应得出，新型墩柱整体承载力提高31%;采用等效套箍系数计算的新型墩柱承载力与试验值绝对误差在4%以内，说明新型复式钢管混凝土墩柱符合钢管混凝土统一理论。研究结果表明，新型复式钢管混凝土墩柱在约束混凝土效应方面明显提高，构件的承载力较高、延性较好，具有较强的工程应用前景。

关键词：新型复式钢管混凝土墩柱轴压性能破坏形态承载力套箍系数

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Theoretical Study on Reaction Mechanism of Aluminum-Water System

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Chinese Journal of Chemical Physics 2008年第3期21卷 245-249页

作者： yun-lan Sun Yan Tian Shu-fen Li Department of Chemical Physics University of Science and Technology of China Hefei 230026 China School of Metallurgy and Resources Anhui University of Technology Maanshan 243002 China

A theoretical study on the reaction of aluminum with water in the gas phase was performed using the hybrid density functional B3LYP and QCISD（T） methods with the 6-311＋G（d,p） and the 6-311＋＋G（d,p） basis sets. The results show that there are three possible reaction pathways that involve four isomers, seven transition structures, and two possible products for the reaction of aluminum with water. The two most favorable reaction pathways were found, whose intermediates and products agreed quite well with experimental results. The enthalpy and Gibbs free energy change of the reaction between A1 and H2O at 298 and 2000 K were calculated. Some results are also in good agreement with the previous calculations or experimental results.

关键词： Aluminum Water Reaction mechanism Hybrid density functional theory

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Application of Gene Therapy in Hemophilia

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Current Medical Science 2022年第5期42卷 925-931页

作者： Yue-fen HU yun-hai FANG yong-rong LAI Xiao-qin fenG Shu-qian XU Department of Hematology Qilu HospitalCheeloo College of MedicineShandong UniversityJinan 250014China Shandong Blood Center Shandong Hemophilia Treatment CenterJinan 250014China Department of Hematology the First Affiliated Hospital of Guangxi Medical UniversityNanning 530021China Nanfang Hospital Southern Medical UniversityGuangzhou 510000China

Gene therapy refers to introducing normal exogenous genes into target cells to correct or compensate for the diseases caused by defective and abnormal genes for the purpose of *** holds out hope of a cure for single-gene genetic diseases such as thalassemia,hemophilia,*** present,gene therapy is performed in two ways:introducing exogenous genes,and gene editing.A great number of clinical trials of gene therapy in hemophilia have been carried out using viral vectors to introduce foreign genes into target ***,the production of neutralizing antibodies following injection and the inability to prepare viral vectors in large quantities limit their *** gene-editing methods like CRISPR avoid the above problems,the potential risks of off-target effects are still *** trials and evidence are needed to elucidate the safety and accuracy of gene *** paper will review the bench and clinical work of gene therapy in hemophilia in recent years,and summarize the challenges and prospects of gene therapy,so as to provide directions for future scientific research in this field.

关键词： hemophilia gene therapy CRISPR-Cas9 application

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Solid-phase extraction gold from alkaline cyanide solution with quaternary ammonium surfactant

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Rare Metals 2016年第3期35卷 282-288页

作者： Run-Fang Xie Qiu-fen Hu Guang-Yu Yang Jing Chen yun-Shan Han yong-He Zhao Zhen Li School of Forensic Medicine Kunming Medical University School of Chemical Science and Technology Yunnan University Inspection and Analysis Center Yunnan Copper Industry Limited by Share Ltd

The solid-phase extraction（SPE） technique applied to the extraction of organic compound was creatively used as the extraction of inorganic gold in the *** types of techniques were proposed and explored,namely the SPE and the liquid–liquid extraction（LLE） of the quaternary ammonium surfactant [cetytrimethyl ammonium bromide（CTMAB）,cetyl pyridine bromide（CPB）,benzyl dimethyl dodecyl ammonium chloride（BDMDAC）,and dodecyl trimethyl ammonium chloride（DTMAC）].The surfactant could react with Au（CN）2^- to form the ionic complex,and the compound could be extracted by SPE column of reversed-phase bonded silica ***,a new method of SPE was proposed to extract gold with these features of the high selectivity,the reliability,and the *** experimental result shows that the recovery rate of gold is more than 98 %,and the solid-phase extraction column is not easily damaged and it can be repeatedly *** new method can be used as the extraction process of gold from alkaline cyanide solution as ***,the paper also puts forward a new process of gold extraction.

关键词： Solid-phase extraction Surfactant Alkaline cyanide solution Gold Mechanism

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Integrating Factors and Conservation Theorems of Lagrangian Equations for Nonconservative Mechanical System in Generalized Classical Mechanics

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Communications in Theoretical Physics 2006年第1X期46卷 43-45页

作者： QIAO yong-fen ZHAO Shu-Hong Department of Mechanical Engineering and Automation Zhejiang Science and Technology University Hangzhou 310018 China Engineering College of Northeast Agricultural University Harbin 150030 China

The conservation theorems of the generalized Lagrangian equations for nonconservative mechanical system are studied by using method of integrating factors. Firstly, the differential equations of motion of system are given, and the definition of integrating factors is given. Next, the necessary conditions for the existence of the conserved quantity are studied in detail. Finally, the conservation theorem and its inverse for the system are established, and an example is given to illustrate the application of the result.

关键词： generalized nonconservative system Lagrangian equation conservation theorem integrating factor

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Transition of One Mode-Phase at the Crisis and Onset of Spatiotemporal Chaos

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Chinese Physics Letters 2001年第2期18卷 178-180页

作者： HE Kai-fen ZHANG Hai-yun Key Laboratory in University for Radiation Beam Technology and Materials Modification Beijing Normal UniversityBeijing 100875 Institute of Low Energy Nuclear Physics Beijing Normal UniversityBeijing 100875 Beijing Radiation Center Beijing 100875

In our previous work[***.80(1998)696]we investigated a crisis-induced transition from temporal chaos to spatiotemporal chaos(STC)due to a collision between the unstable orbit of the carrier saddle steady wave(SSW)and the attractor of its perturbation wave(PW).In this letter,we find that at the crisis one PW mode-phase experiences a state *** variations of PW mode-phases are governed by the linear dispersion as well as two competitive effects arising from the system nonlinearity:(1)interaction between the SSW and the PW(SP);(2)self-nonlinearity of the PW(PP).With the increasing importance of system nonlinearity we find that before the crisis for all PW modes the SP effects dominate and the mode-phases vibrate chaotically;while after the crisis for one PW mode the PP effect surpasses that of SP,in which case the phase transits to a state of combination of chaotic whirling and vibrating,which is different from the case of weak *** the meantime,the PW partial wave is free from the trapping of its carrier,and can be driven or damped chaotically depending on the phase difference relative to the carrier SSW,causing the STC motion after the crisis.

关键词： nonlinearity chaotic chaos

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一株同步硝化反硝化菌株的筛选及其生物电化学脱氮性能研究

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南京农业大学学报 2025年第1期48卷 133-143页

作者：田瑞瑞付欢郑云黄新琦周俊雍晓雨南京工业大学生物与制药工程学院江苏南京211816 南京师范大学地理科学学院江苏南京210023

[目的]本文旨在获得具有高效脱氮性能的异养硝化-好氧反硝化(heterotrophic nitrification-aerobic denitrification,HN-AD)功能菌株,构建生物电化学-同步硝化反硝化(bio-electrochemical systems-simultaneous nitrification and denitrification,BES-SND)耦合系统,实现脱氮效率的提升。[方法]从活性污泥中筛选HN-AD菌株,鉴定后通过摇瓶试验分析其脱氮性能。然后进一步研究碳源、C/N、溶解氧等外界因素对菌株同步硝化反硝化性能的影响。将菌株接种到微生物燃料电池(microbial fuel cells,MFC)的生物阴极,分析低C/N条件下BES-SND体系的脱氮性能。[结果]从活性污泥中筛选出一株具有同步硝化反硝化性能的HN-AD菌株,命名为Alcaligenes aquatilis N3。确定该菌株发生SND反应的最适碳源为乙酸钠、C/N值为20、溶解氧为3.70 mg·L^(-1)。在BES-SND脱氮体系中,C/N值分别为2、4、6、8时,菌株*** N3的总氮去除率分别为20.51%、26.67%、37.76%和48.50%。在C/N=2的试验条件下,BES-SND系统的总氮去除速率在第5天仍为1.79 mg·L^(-1)·d^(-1)。[结论]在低碳环境下,*** N3菌株依然可以在BES-SND耦合脱氮体系中实现脱氮,降低了脱氮过程对碳源的依赖性,具有一定的实际环境应用潜力。

关键词：同步硝化反硝化异养硝化-好氧反硝化生物电化学低C/N值微生物燃料电池

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