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Emergency response facility location in transportation networks: A literature review

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Journal of Traffic and Transportation Engineering(English Edition) 2021年第2期8卷 153-169页

作者： Yang Liu yun yuan Jieyi Shen Wei Gao College of Artificial Intelligence Nanjing Agricultural UniversityNanjing 210031China College of Transportation Engineering Dalian Maritime UniversityDalian 116026China College of Engineering University of UtahSalt Lake CityUT 84112USA

Emergency response activity relies on transportation networks. Emergency facility location interacts with transportation networks clearly. This review is aimed to provide a combined framework for emergency facility location in transportation networks. The article reveals emergency response activities research clusters, issues, and objectives according to keywords co-occurrence analysis. Four classes of spatial separation models in transportation networks, including distance, routing, accessibility, and travel time are introduced. The stochastic and time-dependent characteristics of travel time are described. Travel time estimation and prediction method, travel time under emergency vehicle preemption,transportation network equilibrium method, and travel time in degradable networks are demonstrated. The emergency facilities location models interact with transportation networks, involving location-routing model, location models embedded with accessibility,location models embedded with travel time, and location models employing mathematical program with equilibrium constraints are reviewed. We then point out the-state-of-art challenges: ilities-oriented, evolution landscape and sequential decision modelling, datadriven optimization approach, and machine learning-based algorithms.

关键词： Transportation engineering Emergency facility location Transportation networks Travel time Machine learning

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Overexpression of OsJAC1, a Lectin Gene, Suppresses the Coleoptile and Stem Elongation in Rice

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Journal of Integrative Plant Biology 2007年第2期49卷 230-237页

作者： Jia-Fu Jiang yun-yuan Xu Kang Chong Research Center for Molecular & Developmental Biology Key Laboratory of Photosynthesis and Environmental Molecular Physiology the Chinese Academy of Sciences Beijing 100093 China Graduate School of the Chinese Academy of Sciences Beijing 100049 China

Lectin plays an Important role In defense signaling In plants, but its function In plant growth and development is not well known. Previously, we cloneds rice （Oryza sativa L.） gene OsJAC1 encoding s msnnose-blndlng Jscslln-relsted lectln, and found that OsJAC1 was Jssmonlc acid （JA） Inducible. Here we cloned the promoter of OsJAC1, and GUS activity was detected In young roots, coleoptlles, sheaths, leaves, nodes of stems, stems, rschlses, pistils, stsmens and lemmss of OsJAC1：：GUS trsnsgenlc rice, suggesting that OsJAC1 Is s constitutive expression gene In rice. Moreover, OsJAC1-overexpressed （Ubi：：OsJAC1） rice showed dwarfism with shorter coleptlles resulting from the failure of cell elongation of coleoptlles. In addition, compared with coleoptlles of wild-type plants, those of OsJAC1 overexpresslon rice were more sensitive to JA treatment. These data revealed that, besides Its roles in defense response, lectin plays an Important role in rice growth and development.

关键词： coleoptile jasmonic acid mannose-binding lectin Oryza sativa OsJAC1.

Preparation of Flaky Hexagonal Nanoporous Au-Cu and Au Particles via Dealloying

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Acta Metallurgica Sinica(English Letters) 2022年第11期35卷 1777-1786页

作者： Jing Deng yuan-yun Zhao Yong Shen Chuntao Chang Qiang Li School of Physics Science and Technology Xinjiang UniversityUrumqi 830046China Neutron Scattering Technical Engineering Research Center School of Mechanical EngineeringDongguan University of TechnologyDongguan 523808China Guangdong-HongKong-Macao Joint Laboratory for Neutron Scattering Science and TechnologyDongguan University of TechnologyDongguan 523808China Instituteof Metal Research Chinese Academy of SciencesShenyang 110016China

Nanoporous metals have attracted signifi cant attention owing to their excellent physical,chemical,and biological ***,preparing ultrafi ne nanoporous metal particles(1–5μm)with specifi c geometries remains ***,we report a simple strategy to prepare ultrafi ne fl aky hexagonal nanoporous Au-Cu and Au particles via ***-based alloy ribbons with ultrafi ne fl aky hexagonal Mg-Au(Cu)-Gd particles dispersed in a Mg-Cu(Au)-Gd metallic glassy matrix were *** size and morphology of the precipitated fl aky hexagonal Mg-Au(Cu)-Gd particles were controlled by the solidifi cation process of a Mg 61 Cu 21 Au 7 Gd 11 alloy *** ne fl aky hexagonal nanoporous Au-Cu particles(diagonal diameter 2.58±0.44μm,ligament size~28 nm),Au-1 particles(diagonal diameter 2.38±0.35μm,ligament size~83 nm)and Au-2 particles(diagonal diameter 2.39±0.44μm,ligament size~66 nm)were prepared via ultrasonic-assisted dealloying of Mg 61 Cu 21 Au 7 Gd 11 alloy ribbons in 0.25 M HCl/ethanol,1 M HCl/ethanol and 0.25 M HNO 3/ethanol solutions,*** ultrafi ne fl aky hexagonal nanoporous Au-Cu and Au particles with a large specifi c surface area have a uniform particle size and shape,implying that they possess adequate powder fl uidity and excellent catalytic ***,the formation mechanism of the MgAu(Cu)Gd phase in solidifi ed Mg-Cu-Au-Gd alloys was *** study provides a novel approach for synthesizing nanoporous metal particles with a specifi c geometry.

关键词： Metallic glasses Mg-based alloys Dealloying Nanoporous particles Mg-Au-Gd phase

Simulations on the multi-shell target ignition driven by radiation pulse in Z-pinch dynamic hohlraum

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Chinese Physics B 2021年第11期30卷 411-418页

作者： Shi-Jia Chen Yan-yun Ma Fu-yuan Wu Xiao-Hu Yang yun yuan Ye Cui Rafael Ramis Department of Physics National University of Defense TechnologyChangsha 410073China IFSA Collaborative Innovation Center Shanghai Jiao Tong UniversityShanghai 200240China College of Advanced Interdisciplinary Studies National University of Defense TechnologyChangsha 410073China Laboratory of Laser Plasmas School of Physics and Astronomy Shanghai Jiao Tong UniversityShanghai 200240China E.T.S.I.Aeronautica y del Espacio Universidad Politecnica de MadridSpain

We present the first simulation results of a multi-shell target ignition driven by Z-pinch dynamic hohlraum radiation *** radiation pulse is produced with a special Z-pinch dynamic hohlraum configuration,where the hohlraum is composed of a single metal liner,a low-Z plastic foam,and a high-Z metallic *** implosion dynamics of a hohlraum and a multi-shell target are investigated separately by the one-dimensional code *** the peak drive current is 50 MA,simulations suggest that an x-ray pulse with nearly constant radiation temperature(-310 eV)and a duration about 9 ns can be obtained.A small multi-shell target with a radius of 1.35 mm driven by this radiation pulse is able to achieve volumetric ignition with an energy gain(G)about 6.19,where G is the ratio of the yield to the absorbed *** this research,we better understand the effects of non-uniformities and hydrodynamics instabilities in Z-pinch dynamic hohlraum.

关键词： Z-pinch dynamic hohlraum radiation pulse volumetric ignition

TWO ALGORITHMS FOR LC^1 UNCONSTRAINED OPTIMIZATION

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Journal of Computational Mathematics 2000年第6期18卷 621-632页

作者： Wen-yu Sun R.J.B.de Sampaio Jin-yun yuan School of Mathematics and Computer Science Nanjing Normal UniversityNanjing 210097China Applied Informatics Program Pontifical Catholic University of ParanaCuritibaPR81611-970Brazil Department of Mathematics Federal University of ParanaCuritibaPR81531-990Brazil

Presents two algorithms for LC unconstrained optimization problems which use the second order Dini upper directional derivative. Simplicity of the methods to use and perform; Discussion of related properties of the it... 详细信息

关键词： nonsmooth optimization directional derivative Newton-like method convergence trust region method

Gene Therapy Activates Retinal Pigment Epithelium Cell Proliferation for Age-related Macular Degeneration in a Mouse Model

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Current Medical Science 2023年第2期43卷 384-392页

作者： yun yuan Wen KONG Xiao-mei LIU Guo-hua SHI School of Biomedical Engineering(Suzhou) Division of Life Sciences and MedicineUniversity of Science and Technology of ChinaSuzhou215000China Suzhou Institute of Biomedical Engineering and Technology Chinese Academy of ScienceSuzhou215000China

Objective Age-related macular degeneration(AMD)is a degenerative retinal *** degeneration or death of retinal pigment epithelium(RPE)cells is implicated in the pathogenesis of *** study aimed to activate the proliferation of RPE cells in vivo by using an adeno-associated virus(AAV)vector encodingβ-catenin to treat AMD in a mouse *** Mice were intravitreally injected with AAV2/8-Y733F-VMD2-β-catenin for 2 or 4 weeks,andβ-catenin expression was measured using immunofluorescence staining,real-time quantitative reverse transcription polymerase chain reaction(PCR),and Western *** function ofβ-catenin was determined using retinal flat mounts and laser-induced damage ***,the safety of AAV2/8-Y733F-VMD2-β-catenin was evaluated by multiple intravitreal *** AAV2/8-Y733F-VMD2-β-catenin induced the expression ofβ-catenin in RPE *** activated the proliferation of RPE cells and increased cyclin D1 *** was beneficial to the recovery of laser-induced damage by activating the proliferation of RPE ***,it could induce apoptosis of RPE cells by increasing the expression of Trp53,Bax and caspase3 while decreasing the expression of *** AAV2/8-Y733F-VMD2-β-catenin increasedβ-catenin expression in RPE cells,activated RPE cell proliferation,and helped mice heal from laser-induced eye ***,it could induce the apoptosis of RPE ***,it may be a safe approach for AMD treatment.

关键词： gene therapy adeno-associated virus age-related macular degeneration retinal pigment epithelium cells β-catenin

Systematic bibliometric analysis of research hotspots and trends on the application of premium IOLs in the past 2 decades

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International Journal of Ophthalmology(English edition) 2024年第4期17卷 736-747页

作者： Liang-Pin Li Li-yun yuan De-Shen Mao Xia Hua Xiao-Yong yuan Clinical College of Ophthalmology Tianjin Medical UniversityTianjin 300020China Tianjin Key Laboratory of Ophthalmology and Visual Science Tianjin Eye InstituteTianjin Eye HospitalTianjin 300020China School of Medicine Nankai UniversityTianjin 300071China Anhui Medical University Hefei 230032Anhui ProvinceChina Tianjin Aier Eye Hospital Tianjin UniversityTianjin 300190China

AIM:To analysis of research hotspots and trends on the application of premium intraocular lens(PIOLs)in the past 2 ***:The literature search was performed on the Web of Science and included PIOLs studies published between January 2000 and December *** retrieved literature was collated and analyzed by R-tool’s Bibliometrix package,CitNetExplorer,CiteSpace and other ***:A total of 1801 articles about PIOLs were obtained,most of which were published in Spain and the United *** organization that published the most articles was the University of Valencia in ***ó JL,and Montés-Micó R,from Spain were the most influential authors in this *** Journal of Cataract and Refractive Surgery and Journal of Refractive Surgery were the core journals for this field;the top 10 cited articles mainly focus on postoperative satisfaction with multifocal intraocular lens(IOLs)and postoperative results of toric *** the keyword analysis,we found that trifocal IOLs,astigmatism and extended depth of focus(EDoF)IOLs are the most discussed topics at present,and the importance of astigmatism and the clinical application of the new generation of PIOLs are the emerging research ***:Bibliometric analysis can effectively help to identify multilevel concerns in PIOLs research and the prevailing research trends in the realm of PIOLs encompass the adoption of EDoF IOLs,trifocal IOLs,and their respective Toric models.

关键词： premium intraocular lens bibliometric H-index cataract surgery global trends

Intein-mediated Rapid Purification of Recombinant Human Pituitary Adenylate Cyclase Activating Polypeptide

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Acta Biochimica et Biophysica Sinica 2004年第11期36卷 759-766页

作者： Rong-jie YU, An HONG, yun DAI, and yuan GAOBio-engineering Institute of Jinan University, Guangzhou 510632, China Bio-engineering Institute of Jinan University Guangzhou 510632 China

In order to obtain the recombinant human PACAP efficiently by intein-mediated single column purification, a gene encoding human PACAP was synthesized and cloned into Escherichia coli expression vector pKYB. The recomb... 详细信息

关键词： intein recombinant human pituitary adenylate cyclase activating peptide (rhPACAP) purification

The Effect of the Relative Velocity on Traffic Flow

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Communications in Theoretical Physics 2002年第8期38卷 230-234页

作者： XUE Yu DONG Li-yun yuan Yi-Wu DAI Shi-Qiang Shanghai Institute of Applied Mathematics and Mechanics Shanghai University Shanghai 200072 China Department of Physics Guangxi University Nanning 530003 China Shanghai Institute of Applied Mathematics and Mechanics Shanghai University Shanghai 200072 China Shanghai Institute of Applied Mathematics and Mechanics Shanghai University Shanghai 200072 China Shanghai Institute of Applied Mathematics and Mechanics Shanghai University Shanghai 200072 China

The optimal velocity model of traffc is extended to take the relative velocity into account. The traffcbehavior is investigated numerically and analytically with this model. It is shown that the car interaction with therelative velocity can effect the stability of the traffic flow and raise critical density. The jamming transition between thefreely moving and jamming phases is investigated with the linear stability analysis and nonlinear perturbation *** traffic jam is described by the kink solution of the modified Korteweg-de Vries equation. The theoretical result isin good agreement with the simulation.

关键词： optimal velocity model, relative velocity, jamming transition, traffic flow