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Multi-Level Parallel Network for Brain Tumor Segmentation

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Computer Modeling in Engineering & Sciences 2024年第4期139卷 741-757页

作者： Juhong Tie Hui peng School of Software Engineering Chengdu University of Information TechnologyChengdu610225China

Accurate automatic segmentation of gliomas in various sub-regions,including peritumoral edema,necrotic core,and enhancing and non-enhancing tumor core from 3D multimodal MRI images,is challenging because of its highly heterogeneous appearance and *** convolution neural networks(CNNs)have recently improved glioma segmentation ***,extensive down-sampling such as pooling or stridden convolution in CNNs significantly decreases the initial image resolution,resulting in the loss of accurate spatial and object parts information,especially information on the small sub-region tumors,affecting segmentation ***,this paper proposes a novel multi-level parallel network comprising three different level parallel subnetworks to fully use low-level,mid-level,and high-level information and improve the performance of brain tumor *** also introduce the Combo loss function to address input class imbalance and false positives and negatives imbalance in deep *** proposed method is trained and validated on the BraTS 2020 training and validation *** the validation dataset,ourmethod achieved a mean Dice score of 0.907,0.830,and 0.787 for the whole tumor,tumor core,and enhancing tumor core,*** with state-of-the-art methods,the multi-level parallel network has achieved competitive results on the validation dataset.

关键词： Convolution neural network brain tumor segmentation parallel network

Brain Mechanisms Underlying Panic Attack and Panic Disorder

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Neuroscience Bulletin 2024年第6期40卷 795-814页

作者： Xuyan Guan peng Cao Tsinghua Institute of Multidisciplinary Biomedical Research Tsinghua UniversityBeijing102206China National Institute of Biological Sciences(NIBS) Beijing102206China

Panic disorder is a psychiatric disorder characterized by recurrent panic attacks,with a prevalence of~4%in the general population,causing heavy personal and socioeconomic *** similarities of animal defense responses to clinical panic attack symptoms in humans make it possible to translate neuroanatomical pathways identified in animal studies to panic disorder in ***,in this review we first present a basic overview of panic disorder in humans including the main subtypes,models commonly used to trigger panic attacks,related hypotheses,the neurotransmitter systems that may be involved,and the current clinical treatments to give the reader a comprehensive understanding of panic *** animal section introduces the models that trigger panic-like behavior in animals and the brain regions that may be involved,providing insights for future elucidation of the neural circuit mechanisms behind panic attacks.

关键词： Panic disorder Panic attack Defense responses Animal studies Humans

嗜黏蛋白阿克曼菌在疾病中的保护性作用及机制研究进展

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微生物学通报 2022年第5期49卷 1912-1926页

作者：陶晴王嫘彭宇明高千南京大学医学院转化医学中心江苏省分子医学技术重点实验室江苏南京210093

嗜黏蛋白阿克曼菌(Akkermansia muciniphila,Akk)是人类肠道正常存在的常见共生菌,丰度约占肠菌的1%−3%。Akk是极少数已知在肠道平衡态下仍能引发T细胞依赖性免疫作用的肠菌,提示该菌可能参与正常肠道免疫耐受过程。疾病和模型动物研究... 详细信息

嗜黏蛋白阿克曼菌(Akkermansia muciniphila,Akk)是人类肠道正常存在的常见共生菌,丰度约占肠菌的1%−3%。Akk是极少数已知在肠道平衡态下仍能引发T细胞依赖性免疫作用的肠菌,提示该菌可能参与正常肠道免疫耐受过程。疾病和模型动物研究表明,Akk在改善宿主代谢功能和免疫应答方面具有重要作用,近期引起广泛关注。目前相关研究大多集中在Akk与疾病的相关性上,尚无系统阐述其作用机制的研究。本文对Akk与人体几大重要系统疾病和免疫之间的关联及其作用机制进行论述,以期为Akk的有效利用提供证据和思路。

关键词：嗜黏蛋白阿克曼菌肠道免疫稳态代谢性疾病神经性疾病癌症

汇流排产热影响下的电池模组冷却系统改进设计

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汽车工程 2022年第6期44卷 859-867页

作者：彭宇明袁明晓敬卓鑫张永林黄港先进驱动节能技术教育部工程研究中心成都610036 西南交通大学汽车与能源动力研究所成都610036

本文利用Bernardi生热速率方程,通过仿真和实验验证建立了可靠的电芯生热模型,仿真和实验误差在2%以内。在此基础上建立汇流排产热影响下的模组生热模型,针对原冷却系统对模组顶部区域和汇流排上冷却效果不足等进行改进设计,在冷却板布... 详细信息

本文利用Bernardi生热速率方程,通过仿真和实验验证建立了可靠的电芯生热模型,仿真和实验误差在2%以内。在此基础上建立汇流排产热影响下的模组生热模型,针对原冷却系统对模组顶部区域和汇流排上冷却效果不足等进行改进设计,在冷却板布置方式上提出将冷却板布置在模组侧面,再通过仿真分析选取合适的冷却板厚度、冷却液体积浓度和冷却液入口流速,最终设计的冷却系统模组汇流排体平均温升降低了15.56%,电芯体平均温升降低了11.48%,模组顶部表面平均温升降低了20.34%,同时模组电芯上的温度分布也更加均匀。

关键词：方形锂离子电池汇流排 COMSOL Multiphysic 液体冷却系统

Long-time Asymptotics for the Reverse Space-time Nonlocal Hirota Equation with Decaying Initial Value Problem:without Solitons

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Acta Mathematicae Applicatae Sinica 2024年第3期40卷 708-727页

作者： Wei-qi peng Yong CHEN School of Mathematical Sciences East China Normal UniversityShanghai 200241China College of Mathematics and Systems Science Shandong University of Science and TechnologyQingdao 266590China

In this work,we mainly consider the Cauchy problem for the reverse space-time nonlocal Hirota equation with the initial data rapidly decaying in the solitonless *** from the Lax pair,we first construct the basis Riemann-Hilbert problem for the reverse space-time nonlocal Hirota ***,using the approach of Deift-Zhou nonlinear steepest descent,the explicit long-time asymptotics for the reverse space-time nonlocal Hirota is *** the reverse space-time nonlocal Hirota equation,since the symmetries of its scattering matrix are different with the local Hirota equation,the v(λ_(i))(i=0,1)would like to be imaginary,which results in theδ_(λi)^(0)contains an increasing t(±Imv(λ_(i)))/2,and then the asymptotic behavior for nonlocal Hirota equation becomes differently.

关键词： Riemann-Hilbert problem reverse space-time nonlocal Hirota equation long-time asymptotics nonlinear steepest descent method

Response of runoff and its components to climate change in the Manas River of the Tian Shan Mountains

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Advances in Climate Change Research 2024年第1期15卷 62-74页

作者： Ze-Long YANG peng BAI Key Laboratory of Water Cycle and Related Land Surface Processes Institute of Geographic Sciences and Natural Resources ResearchChinese Academy of SciencesBeijing 10010lChina University of Chinese Academy of Sciences Beijing 100049China

A warming-wetting climate trend has led to increased runoff in most watersheds in the Tian Shan Mountains over the past few ***,it remains unclear how runoff components,that is,rainfall runoff(Rrain),snowmelt runoff(Rsnow),and glacier meltwater(Rglacier),responded to historical climate change and how they will evolve under future climate change ***,we used a modified Hydrologiska Byrans Vattenbalansavdelning(HBV)model and a detrending method to quantify the impact of precipitation and temperature changes on runoff components in the largest river(Manas River)on the northern slope of the Tian Shan Mountains from 1982 to 2015.A multivariate calibration strategy,including snow cover,glacier area,and runoff was implemented to constrain model parameters associated with runoff *** downscaled outputs of 12 general circulation models(GCMs)from the Sixth Coupled Model Intercomparison Project(CMIP6)were also used to force the modified HBV model to project the response of runoff and its components to future(2016-2100)climate change under three common socio-economic pathways(SSP126,SSP245,and SSP585).The results indicate that Rrain dominates mean annual runoff with a proportion of 42%,followed by Rsnow(37%)and Rglacier(21%).In terms of inter-annual variation,Rrain and Rsnow show increasing trends(0.93(p0.05)mm per year),while Rglacier exhibits an insignificant(p>0.05)decreasing trend(-0.12 mm per year),leading to an increasing trend in total runoff(1.12 mm per year,p>0.05).The attribution analysis indicates that changes in precipitation and temperature contribute 8.16 and 10.37 mm,respectively,to the increase in runoff at the mean annual *** wetting(increased precipitation)increases Rrain(5.03 mm)and Rsnow(3.19 mm)but has a limited effect on Rglacier(-0.06 mm),while warming increases Rrain(10.69 mm)and Rglacier(5.79 mm)but decreases Rsnow(-6.12 mm).The negative effect of glacier shrinkage on Rglacier has outweighed the

关键词： Tian Shan Rainfall runoff Snowmelt runoff Glacier meltwater Warming-wetting Tipping point

Highly efficient capture of thorium ion by citric acid-modified chitosan gels from aqueous solution

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Chinese Chemical Letters 2024年第5期35卷 361-365页

作者： Linshan peng Qihang peng Tianxiang Jin Zhirong Liu Yong Qian State Key Laboratory of Nuclear Resources and Environment East China University of TechnologyNanchang 330013China Jiangxi Province Key Laboratory of Polymer Micro/Nano Manufacturing and Devices East China University of TechnologyNanchang 330013China

A novel citric acid-modified chitosan gel(CSCA)was synthesized through a simple one-step process and was used to extract thorium ions from *** CSCA samples with varying chemical compositions were analyzed using SEM with mapping EDS,FT-IR,and static water contact angle measurements,and their adsorption behaviors were studied in *** results showed that the adsorption performance of CSCA improves with the increase of CA content in the *** possesses an impressive capacity for thorium adsorption of 279.8 mg/***,it showed an ultra-fast adsorption rate and reached equilibrium within 30 *** terms of recyclability,the CSCA still retained more than 86%of its initial adsorption capacity after 6 cycles of *** functional theory(DFT)analysis reveals that the good selectivity of this material towards thorium ions should be attributed to the high density of adsorption sites and strong interaction between carboxyl groups and thorium *** work could be beneficial in the design and synthesis of new polymer materials for extracting thorium.

关键词： Thorium Adsorption Citric acid Chitosan DFT calculation

Some Rotundities of Orlicz–Lorentz Spaces

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Acta Mathematica Sinica,English Series 2024年第8期40卷 1893-1919页

作者： Wan Zhong GONG peng WANG Department of Mathematics Anhui Normal UniversityWuhu 241000P.R.China

K-UR,K-LUR and K-R are the generalizations of UR,LUR and R respectively,which are of great significance in Banach space *** in Orlicz–Lorentz function spaceΛ_(ϕ,ω)^(◦)[0,γ)equipped with the Orlicz norm,the research methods of K-UR,K-LUR and K-R are much more complicated than those of UR,LUR and *** this paper we obtain some criteria of K-UR,K-LUR and K-R ofΛ_(ϕ,ω)^(◦)[0,γ)by means of the norm of dual space and H_(μ)property ofΛ_(ϕ,ω)^(◦)[0,γ).

关键词： Orlicz-Lorentz space Orlicz norm k-uniform rotundity locally k-uniform rotundity krotundity

Effects of cooling rate on microstructure and microhardness of directionally solidified Galvalume alloy

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China Foundry 2024年第3期21卷 213-220页

作者： Ji-peng Li De-gao Qiao Jian Li Xiao-yang Luo peng peng Xian-tao Yan Xu-dong Zhang Gansu Jiu Steel Group Hongxing Iron and Steel Co. Ltd.Jiayuguan 735111GansuChina School of Materials and Energy Lanzhou UniversityLanzhou 730000China

The influences of cooling rate on the phase constitution,microstructural length scale,and microhardness of directionally solidified Galvalume(Zn-55Al-1.6Si)alloy were investigated by directional solidification experiments at different withdrawal speeds(5,10,20,50,100,200,and 400μm·s^(-1)).The results show that the microstructure of directionally solidified Galvalume alloys is composed of primary Al dendrites,Si-rich phase and(Zn-Al-Si)ternary eutectics at the withdrawal speed ranging from 5 to 400μm·s^(-1).As the withdrawal speed increases,the segregation of Si element intensifies,resulting in an increase in the area fraction of the Si-rich *** addition,the primary Al dendrites show significant refinement with an increase in the withdrawal *** relationship between the primary dendrite arm spacing(λ_(1))and the thermal parameters of solidification is obtained:λ_(1)=127.3V^(-0.31).Moreover,as the withdrawal speed increases from 5 to 400μm·s^(-1),the microhardness of the alloy increases from 90 HV to 151 *** is a combined effect of grain refinement and second-phase strengthening.

关键词： Galvalume alloy directional solidification microstructure length scale microhardness