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Acoustic emission characteristics of damage evolution of multi-scale fiber reinforced rubberized concrete under uniaxial compression and tension after being subjected to high temperatures

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Frontiers of Structural and Civil Engineering 2024年第8期18卷 1237-1266页

作者： Shaoqi ZHANG Yao ZHANG Qianru LEI yumeng YANG Yichao wang Fei XU Zhiguo YAN Hehua ZHU Laboratory of Fire Safety School of Safety Engineering and Emergency ManagementShijiazhuang Tiedao UniversityShijiazhuang 050043China Structural Health Monitoring and Control Key Laboratory of Hebei Province Shijiazhuang Tiedao UniversityShijiazhuang 050043China Department of Geotechnical Engineering Tongji UniversityShanghai 200092China

Recently developed multi-scale fiber(i.e.,CaCO3 whisker,polyvinyl alcohol(PVA)fiber,and steel fiber)reinforced rubberized concrete exhibits excellent mechanical properties and spalling resistance at high *** of macro properties such as strength and Young’s modulus cannot reveal and characterize damage mechanisms,particularly those relating to the multi-scale fiber strengthening *** this study,acoustic emission(AE)technology is applied to investigate the impact of multi-scale fiber on the damage evolution of rubberized concrete exposed to high temperatures,under the uniaxial compression and tension loading *** mechanical properties,AE event location,peak frequency,b-value,the ratio of rise time to amplitude(RA),average frequency(AF)values,and AE energy of specimens are *** results show that the number of events observed using AE gradually increases as the loading *** crumb rubber and fibers inhibit the generation and development of the *** is concluded that both the peak frequency and b-value reflect the extension process of *** the cracks develop from the micro scale to the macro scale,the peak frequency tends to be distributed in a lower frequency range,and the b-value decreases *** the peak stress point,the AE energy increases rapidly and the b-value *** specimens without multi-scale fibers exhibit brittle failure,while the specimens with fibers exhibit ductile *** addition,adding multi-scale fibers and crumb rubber increases the peak frequency in the medium and high frequency ranges,indicating a positive effect on inhibiting crack *** being subjected to high temperatures,the maximum and minimum b-values decrease,reflecting an increase in the number of initial cracks due to thermal ***,the RA and AF values are used to classify tensile and shear *** specimens fracture with more shear cracks under compression,and there are more tensile

关键词： multi-scale fibers acoustic emission fracture damage evolution rubberized concrete

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High-temperature elemental segregation induced structure degradation in high-entropy fluorite oxide

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Journal of Advanced Ceramics 2024年第3期13卷 310-322页

作者： Yixuan Hu Mariappan Anandkumar yumeng Zhang Joydip Joardar Atul Suresh Deshpande Xiaodong wang Kolan Madhav Reddy School of Materials Science and Engineering Shanghai Jiao Tong UniversityShanghai 200240China Department of Materials Science and Metallurgical Engineering Indian Institute of Technology HyderabadSangareddy 502285India International Advanced Research Centre for Powder Metallurgy and New Materials(ARCI) Hyderabad 500005India

Fluorite-structured oxides constitute an important category of oxides with a wide range of high-temperature *** the concept of high entropy,high-entropy fluorite oxides(HEFOs)have showcased intriguing high-temperature application ***,unlocking this potential necessitates an assessment of their long-term stability under high-temperature *** this study,we conducted a prolonged heat treatment at 1000℃on typical HEFO,specifically(CeHfZrGdLa)O_(x).After 100 h,high-intensity X-ray diffraction(XRD)revealed a transition from a single-phase fluorite to a multi-phase *** investigation by analytical electron microscoy(AEM)demonstrated that this degradation resulted from facilitated element diffusion and consequent escalating chemical fluctuation at high temperatures,leading to spontaneous segregation and separation of Ce and La elements,forming Ce-rich,La-poor,and La-rich ***,the La-rich phase spontaneously transformed from a fluorite structure(space group Fm3m)to a bixbyite structure(space group Ia3)at elevated temperatures,resulting in the appearance of superstructure reflection in XRD profiles and electron diffraction *** the intricate phase decomposition,the energy band gap showed minimal variation,suggesting potential property stability of(CeHfZrGdLa)O_(x)across a broad range of *** findings offer valuable insights into the future applications of HEFOs.

关键词： phase transition high-temperature stability elemental segregation high-entropy fluorite oxides(HEFOs)

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Isolated Cases of Plague--Inner Mongolia-Beijing, 2019

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China CDC weekly 2019年第1期1卷 13-16页

作者： yumeng wang Lei Zhou Mengguang Fan Quanyi wang Jianyun Li Qun Li Zijian Feng George FGao Cheng Xu Lijuan Chen Wei Li Yanping Zhang National Institute for Communicable Disease Control and Prevention China CDCChangpingBeijingChina State Key Laboratory of Infectious Disease Prevention and Control BeijingChina Chinese Center for Disease Control and Prevention BeijingChina General Center for Disease Control and Prevention of Inner Mongolia Autonomous Region HohhotChina Beijing Center for Disease Control and Prevention BeijingChina The Base for Control and Prevention of Plague and Brucellosis China CDCBaicheng CityJilin ProvinceChina.

What is already known about this topic?Plague is an acute infectious disease caused by Yersinia pestis(***)and is primarily transmitted by *** can be infected by bites of bacterium-bearing fleas or direct contact with diseased or dead plagueinfected *** 2004,the last human plague case was reported in Inner Mongolia Autonomous Region due to skinning a dead *** is added by this report?This is the first case of pneumonic plague imported into a major city since the founding of the People's Republic of *** primary pneumonic plague cases(Patients A and B)found in residents of Inner Mongolia were confirmed in Beijing on November 12,*** case(Patient C)of *** was identified as bubonic plague on November *** A most likely became infected from aerosol exposure to infective droplets while digging on his farm,located in an Meriones unguiculatus(***)natural plague *** B became infected from contact with Patient A(her husband).Patient C became infected after skinning a dead *** was no epidemiological relationship between the Patient A/B and Patient *** are the implications for public health practice?When epizootic plague is detected,local health-care providers and the public should be alerted about any possible *** education efforts should focus on promoting personal protection measures.

关键词： acute founding likely

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基于云计算的工程项目核查系统设计

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电子技术（上海） 2024年第1期53卷 182-183页

作者：王雨萌赵会龙陆勇张献蒙周高伟赵晶国网江苏省电力有限公司建设分公司江苏210009 国网江苏省电力有限公司江苏210018 北京洛斯达科技发展有限公司北京100120

阐述一种基于云计算的输电通道核查系统,分析系统架构和系统功能的特点,实现核查系统的设计。实践应用效果表明,该系统可以全面辅助输电通道的核查。

关键词：云计算工程核查系统输电通道项目

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DeepSecE:A Deep-Learning-Based Framework for Multiclass Prediction of Secreted Proteins in Gram-Negative Bacteria

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Research 2024年第3期2023卷 243-257页

作者： yumeng Zhang Jiahao Guan Chen Li Zhikang wang Zixin Deng Robin BGasser Jiangning Song Hong-Yu Ou state Key Laboratory of Microbial Metabolism Joint International Laboratory on Metabolic&Developmental SciencesSchool of Life Sciences and BiotechnologyShanghai Jiao Tong UniversityShanghai 200240China Shanghai Key Laboratory of Veterinary Biotechnology Shanghai Jiao Tong UniversityShanghai 200240China Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology Monash UniversityMelbourneViC 3800Australia Monash Data Futures Institute Monash UniversityMelbourneViC 3800Australia Melbourne Veterinary School Faculty of ScienceThe University of MelbourneParkvilleVIC 3010Australia.

Proteins secreted by Gram-negative bacteria are tightly linked to the virulence and adaptability of these microbes to environmental *** identification of such secreted proteins can facilitate the investigations of infections and diseases caused by these bacterial ***,current bioinformatic methods for predicting bacterial secreted substrate proteins have limited computational efficiency and application scope on a genome-wide ***,we propose a novel deep-learning-based framework—DeepSecE—for the simultaneous inference of multiple distinct groups of secreted proteins produced by Gram-negative *** remarkably improves their classification from nonsecreted proteins using a pretrained protein language model and transformer,achieving a macro-average accuracy of 0.883 on 5-fold *** benchmarking suggests that DeepSecE achieves competitive performance with the state-of-the-art binary predictors specialized for individual types of secreted *** attention mechanism corroborates salient patterns and motifs at the N or C termini of the protein *** this pipeline,we further investigate the genome-wide prediction of novel secreted proteins and their taxonomic distribution across~1,000 Gram-negative bacterial *** present analysis demonstrates that DeepSecE has major potential for the discovery of disease-associated secreted proteins in a diverse range of Gram-negative *** online web server of DeepSecE is also publicly available to predict and explore various secreted substrate proteins via the input of bacterial genome sequences.

关键词： Deep server competitive

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Food-derived bio-functional peptides for the management of hyperuricemia and associated mechanism

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Food Science and Human Wellness 2024年第4期13卷 1767-1786页

作者： Yanxin wang Mingxia Ma yumeng Huang Siqing Fan Jie Peng Shiming Li Xiurong Su Yanbo wang Chenyang Lu State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-Products and School of Marine Science Ningbo UniversityNingbo 315211China School of Food and Health Beijing Technology and Business UniversityBeijing 100048China Department of Food Science Rutgers UniversityNew BrunswickNJ 08901USA College of Life Sciences Huanggang Normal UniversityHuanggang 438000China Food Safety Key Laboratory of Zhejiang Province School of Food Science and BiotechnologyZhejiang Gongshang UniversityHangzhou 310018China

Hyperuricemia,a metabolic disorder related to uric acid metabolism dysregulation,has become a common metabolic disease worldwide,due to changes in lifestyle and dietary *** recent years,owing to their high activity and few adverse effects,food-derived active peptides used as functional foods against hyperuricemia have attracted increasing *** article aims to focus on the challenge associated with peptide-specific preparation methods development,functional components identification,action mechanism(s)clarification,and bioavailability *** current review proposed recent advances in producing the food-derived peptides with high anti-hyperuricemia activity by protein source screening and matched enzymatic hydrolysis condition adjusting,increased the knowledge about strategies to search antihyperuricemia peptides with definite structure,and emphasized the necessity of combining computer-aided approaches and activity *** addition,novel action mechanism mediated by gut microbiota was discussed,providing different insights from classical ***,considering that little attention was paid previously on the structure-activity relationships of anti-hyperuricemia peptides,we collected the sequences from published studies and make a preliminary summary about the structure-activity relationships,which in turn provided guides for enzymatic hydrolysis optimization and bioavailability ***,this article could promote the development,application and commercialization of food-derived anti-hyperuricemia peptides in the future.

关键词： Hyperuricemia Peptide Enzyme hydrolysis Mechanism Structure-activity relationship Bioavailability

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Effect of High Pressure Homogenization Treatment on Structure and Properties of Soybean Residue Cellulose Nanofibers

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Paper And Biomaterials 2019年第4期4卷 37-44页

作者： Peiyi Li yumeng wang Binyao Zhou Qingqing Hou Hezhen Liu Haozhe Lei Boxing Jian Xinping Li College of Bioresources Chemical and Materials Engineering National Demonstration Center for Experimental Light Chemistry Engineering EducationShaanxi University of Science and TechnologyXi’anShaanxi Province710021China State Key Laboratory of Pulp and Paper Engineering South China University of TechnologyGuangzhouGuangdong Province510640China Department of Chemical and Paper Engineering Western Michigan UniversityKalamazooMichigan49008USA Key Laboratory of Paper Based Functional Materials of China National Light Industry Xi’anShaanxi Province710021China Shaanxi Provincial Key Laboratory of Papermaking Technology and Specialty Paper Development Xi’anShaanxi Province710021China

To reduce the adverse effects of non-cellulose materials on subsequent homogenization,the effects of a high-pressure homogenization treatment on the structure and properties of cellulose nanofibers(CNF)prepared by acid treatment of soybean residue were *** effects of the number of homogenization step on the microfibrillation degree,crystalline structure and mechanical properties of the soybean residue were analyzed by SEM,FT-IR,XRD,TG and *** results showed that an increase in the number of homogenization steps led to an increase in the degree of microfibrillation,a more uniform distribution of the CNF diameter,and an increase in the crystallinity of ***,but when the number of homogenization steps exceeded 15,the rate of change decreased,and the crystallinity of CNF *** the number of homogenization steps increased,the average degree of polymerization and average molecular weight of CNF decreased continuously,and after 15 homogenization steps,their rate of change also ***,15 steps of high-pressure homogenization represented a suitable number of steps to prepare the soybean residue CNF with an average diameter of 15 nm.

关键词： soybean residue cellulose nanofibers high pressure homogenization characteristics

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A commentary on “Acupoint application therapies for essential hypertension:a systematic review and Meta-analysis”

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Journal of Traditional Chinese Medicine 2023年第2期43卷 211-211页

作者： wang yumeng Shou Xintian Li Dong Department of Cardiology Beijing University of Chinese Medicine Dongfang HospitalBeijing 100078China Department of Cardiology China Academy of Chinese Medical Sciences Guang'anmen HospitalBeijing 100053China

Dear editors:We read with interest the article by Liu and colleagues,1 who found that acupoint application(AA) could improve the symptoms of hypertensive patients and reduce blood pressure(BP).AA is an external treatment method of traditional Chinese medicine based on meridian and collateral theory,which exerts a potent antihypertensive *** strongly agree with the conclusion drew by the authors,but still have some concerns and additions.

关键词： hypertensive effect meridian

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ALOXE3基因突变致轻型常染色体隐性先天性鱼鳞病一例

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中国麻风皮肤病杂志 2024年第11期40卷 761-764页

作者：曾琴卢芳琪王雨蒙何伟曹巧玉陈付英王树翠黄海生李明安徽理工大学第一附属医院皮肤科安徽淮南232001 复旦大学附属儿科医院皮肤科上海201102

目的:检测1例常染色体隐性先天性鱼鳞病家系的基因突变情况。方法:提取患者及其父母、100名健康对照外周血DNA,对患者DNA行高通量测序,确定突变位点,再用Sanger测序法对患者和其父母的DNA进行双向验证。结果:在患者DNA中检测到ALOXE3基... 详细信息

目的:检测1例常染色体隐性先天性鱼鳞病家系的基因突变情况。方法:提取患者及其父母、100名健康对照外周血DNA,对患者DNA行高通量测序,确定突变位点,再用Sanger测序法对患者和其父母的DNA进行双向验证。结果:在患者DNA中检测到ALOXE3基因c.1208A>G(***403Arg)及c.1131del(***378Sfs*70)复合杂合突变;母亲检出c.1208A>G(***403Arg)杂合变异,父亲检出c.1131del(***378Sfs*70)杂合变异。在检出的2个突变中,移码突变c.1131del为首次报道的突变。100名健康对照者均未见相同突变。结论:本例患者检测到ALOXE3基因c.1208A>G及c.1131del复合杂合突变,推测错义突变c.1208A>G的存在可能是患者临床表现较轻的原因。新报道的突变(c.1131del)丰富了该病基因突变谱。

关键词：常染色体隐性先天性鱼鳞病 ALOXE3基因复合杂合突变

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AIMP2 restricts EV71 replication by recruiting SMURF2 to promote the degradation of 3D polymerase

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Virologica Sinica 2024年第4期39卷 632-644页

作者： Junrui Ren Lei Yu Qiuhan Zhang Pengyu Ren yumeng Cai Xueyun wang Ke Lan Shuwen Wu State Key Laboratory of Virology College of Life SciencesWuhan UniversityWuhan430072China Medical Research Institute Wuhan UniversityWuhan430072China Taikang Center for Life and Medical Sciences Wuhan UniversityWuhan430072China

Hand,foot and mouth disease(HFMD),mainly caused by enterovirus 71(EV71),has frequently occurred in the Asia-Pacific region,posing a significant threat to the health of infants and young ***,research on the infection mechanism and pathogenicity of enteroviruses is increasingly becoming *** 3D polymerase,as the most critical RNA-dependent RNA polymerase(RdRp)for EV71 replication,is widely targeted to inhibit EV71 *** this study,we identified a novel host protein,AIMP2,capable of binding to 3D polymerase and inhibiting EV71 *** investigations revealed that AIMP2 recruits the E3 ligase SMURF2,which mediates the polyubiquitination and degradation of 3D ***,the antiviral effect of AIMP2 extended to the CVA16 and CVB1 *** research has uncovered the dynamic regulatory function of AIMP2 during EV71 infection,revealing a novel antiviral mechanism and providing new insights for the development of antienteroviral therapeutic strategies.

关键词： AIMP2 Enterovirus 71(EV71) 3D polymerase E3 ligase SMURF2 Ubiquitination

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