检索结果-南通市图书馆

在线全文

学校读者我要写书评

暂无评论

泰安市水资源开发利用现状及建议

山东水利 2024年第6期 50-51,63页

作者：韩玉玲赵发权泰安市岱岳区水利局山东泰安271000

文章对泰安市水资源总量及开发利用现状等情况进行分析,针对水资源开发利用中存在的问题和薄弱环节,提出对策措施,对提高泰安市水资源利用效率和经济社会高质量发展具有重要意义。

关键词：泰安市水资源供水量节水潜力

在线全文

学校读者我要写书评

暂无评论

儿童肥胖与哮喘相关性的研究进展

现代医药卫生 2024年第15期40卷 2646-2650页

作者：王静(综述) 韩玉玲马香(审校) 山东大学附属儿童医院/济南市儿童医院呼吸科山东济南250022 济南市儿童呼吸病重点实验室山东济南250022

儿童肥胖的发病率逐年增高。近年来的研究表明,儿童肥胖是哮喘发生的重要危险因素,而且哮喘也可能导致肥胖的发生。因此,有研究假说认为肥胖和哮喘以多种复杂的方式相互作用。该文从儿童哮喘与肥胖相互作用、肥胖与哮喘双向关系的发病... 详细信息

儿童肥胖的发病率逐年增高。近年来的研究表明,儿童肥胖是哮喘发生的重要危险因素,而且哮喘也可能导致肥胖的发生。因此,有研究假说认为肥胖和哮喘以多种复杂的方式相互作用。该文从儿童哮喘与肥胖相互作用、肥胖与哮喘双向关系的发病机制等进行了综述。

关键词：儿童肥胖哮喘综述

Straw return increases crop grain yields and K-use efficiency under a maize-rice cropping system

在线全文

学校读者我要写书评

暂无评论

The Crop Journal 2021年第1期9卷 168-180页

作者： yuling han Wei Ma Baoyuan Zhou Akram Salah Mingjian Geng Cougui Cao Ming Zhan Ming Zhao MOA Key Laboratory of Crop Physiology Ecology and Cultivation(The Middle Reaches of Yangtze River)College of Plant Science and TechnologyHuazhong Agricultural UniversityWuhan 430070HubeiChina Key Laboratory of Crop Physiology and Ecology Ministry of AgricultureInstitute of Crop SciencesChinese Academy of Agricultural SciencesBeijing 100081China College of Resource and Environment Huazhong Agricultural UniversityWuhan 430070HubeiChina

Straw return is an effective way to improve crop grain yield and potassium(K)use efficiency by increasing soil K ***,the effects of straw return on soil K supplying capacity,replacement of K fertilizer,and K-use efficiency under maize(Zea mays L.)–rice(Oryza sativa L.)cropping systems are little studied.A two-year field experiment was conducted to determine the physiological determinants of K-use efficiency under straw return with four K fertilization ***33(straw returned plus 33%of K fertilizer applied)and Sr67(straw returned plus 67%of K fertilizer applied)increased annual crop yields by 1.5%and 3.2%and increased agronomic K-use efficiency by respectively 2.9 and 1.3-fold on average in the two years,compared with the conventional practice S0K100(no straw returned plus normal amounts of K fertilizer applied).The Sr33 and Sr67 treatments resulted in significantly greater equilibrium K concentration ratios(CR0 K)and specifically exchangeable K(KX)values according to quantity/intensity(Q/I)relationship analyses,indicating improvement of the potential soil K supply ***,the Sr67 better maintained the soil exchangeable K level and K *** results suggested that K released from maize and rice straw can replace about half of chemical K fertilizer,depending on the available K content in maize–rice cropping system production.

关键词： Maize-rice system Straw return K fertilizer K-use efficiency Quantity/intensity curve

在线全文

学校读者我要写书评

暂无评论

绵羊MXD3基因的生物信息学分析

寒旱农业科学 2024年第3期3卷 217-221页

作者：张晏铭韩玉玲马延龙张小雪甘肃农业大学动物科学技术学院甘肃兰州730070

MAX二聚化蛋白3(MAX dimerization protein 3,MXD3)在肿瘤的增殖、凋亡、侵袭和转移过程中起重要作用,广泛存在于多种动物体内。为探究MXD3基因在绵羊体内的功能,运用生物信息学数据库及其软件,分析了该基因及其编码的产物。结果发现,绵... 详细信息

MAX二聚化蛋白3(MAX dimerization protein 3,MXD3)在肿瘤的增殖、凋亡、侵袭和转移过程中起重要作用,广泛存在于多种动物体内。为探究MXD3基因在绵羊体内的功能,运用生物信息学数据库及其软件,分析了该基因及其编码的产物。结果发现,绵羊MXD3基因总共编码了206个氨基酸残基,所编码的蛋白质分子式为C1000H1650N332O315S6,分子质量为23556.50 KDa,理论等电点pI为9.32,半衰期为30 h,不稳定指数为88.30。通过基本理化性质分析可知,绵羊MXD3主要在细胞核发挥作用,不属于分泌蛋白,不存在信号肽序列,不存在跨膜结构,是亲水性蛋白。该蛋白的二级结构主要是以无规卷曲、α螺旋组成,而三级结构预测结果与二级结构相符。

关键词：绵羊 MXD3基因生物信息学分析

Interleukin-25 in sputum as a marker of airway inflammation in children asthma

在线全文

学校读者我要写书评

暂无评论

Science China(Life Sciences) 2019年第12期62卷 1605-1608页

作者： Yun Zhang Cuifen Zhao Xiuxia Zhao Qingyu Kong Mingjie Dingi yuling han Xiang Ma Lu Cheng Department of Respiratory Medicine Qilu Childrens Hospital of Shandong UniversityJinan 250022China Department of Pediatrics Qilu Hospital of Shandong UniversityJinan 250012China

Dear Editor,Interleukin-25(IL-25,also called IL-17E)is an important IL-17 family member that helps initialize and regulate type 2 immunity,exerting an important influence on the pathogenesis of asthma(Corrigan et al.,2011;Barlow et al.,2012).Furthermore,it plays a vital role in initiating type 2 innate lymphoid cell activation and maintenance(Tong and Li,2018)and inducing Th2-type cytokine-mediated allergic airway eosinophilia(Morita et al.,2015).IL-25 expression increases in patients with asthma in different types of lung cells,including lung structural cells(such as endothelium and airway epithelium),eosinophils,T-cells,and mast *** allergen exposure,cells in the bronchial submucosa increase and secrete or respond to IL-25(Corrigan et al.,2011).Plasma IL-25 levels increase in patients with asthma and correlate with lung function(Cheng et al.,2014).The association between IL-25 cells and pulmonary function indicates that IL-25 could be used to monitor asthma *** some mouse models,epithelial IL-25 cytokines are closely related with a range of airway inflammation modalities,including type 2 cytokine production,airway eosinophil inflammation,mucinous epithelial metaplasia,and airway hyperresponsiveness(AHR)(Suzukawa et al.,2012).

关键词： airway inflammation asthma

A green cross-linking method for the preparation of renewable threedimensional graphene sponges for efficient adsorption of Congo red dye

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Chemical Engineering 2024年第2期66卷 84-93页

作者： Zhuang Liu Bo Gao Haoyuan han yuling Li Haiyang Fu Donghui Wei Key Laboratory for Ecological Metallurgy of Multimetallic Mineral(Ministry of Education) Northeastern UniversityShenyang 110819China

Graphene-based materials possess significant potential for the treatment of dye wastewater due to their exceptional adsorption properties toward stubborn ***,their utilization is hindered by high preparation costs,low yields,environmental pollution during synthesis,and challenges in regenerating the *** study proposes a novel approach to address these limitations by developing nitrogen-doped three-dimensional(3D)polyvinyl alcohol(PVA)crosslinked graphene sponges(N-PGA)using a cross-linking method with ammonium *** method offers a relatively mild,environmentally friendly *** carbonate serves as both a reducing and modifying agent,facilitating the formation of the intrinsic structure of N-PGA and acting as a nitrogen ***,PVA is utilized as the cross-linking *** results demonstrate that N-PGA exhibits a favorable internal 3D hierarchical porous structure and possesses robust mechanical *** measured specific surface area(BET)of N-PGA was as high as406.538 m^(2)·g^(-1),which was favorable for its efficient adsorption of Congo red(CR)dye *** an initial concentration of 50 mg·L^(-1),N-PGA achieved an impressive removal rate of 89.6%and an adsorption capacity of 112 mg·g^(-1)for CR ***,it retained 79%of its initial adsorption capacity after 10 cycles,demonstrating excellent regeneration *** summary,the synthesized N-PGA displays remarkable efficacy in the adsorption of CR dye in wastewater,opening up new possibilities for utilizing 3D porous graphene nanomaterials as efficient adsorbents in wastewater treatment.

关键词： Green chemistry Graphene sponge Adsorbents Adsorption Congo red Regeneration

Strategies and opportunities of micro/nano delivery systems for targeted therapy of ulcerative colitis:Focus on underlying mechanisms and future perspectives

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2024年第2期35卷 118-130页

作者： Zihan Liu han Liu Jialing Cheng Hongliang Wang Yanfang Yang Jun Ye yuling Liu State Key Laboratory of Bioactive Substance and Function of Natural Medicines Institute of Materia MedicaChinese Academy of Medical Sciences & Peking Union Medical CollegeBeijing 100050China Beijing Key Laboratory of Drug Delivery Technology and Novel Formulation Institute of Materia MedicaChinese Academy of Medical Sciences & Peking Union Medical CollegeBeijing 100050China

Ulcerative colitis(UC)is a common progressive inflammatory disease whose incidence has increased rapidly in recent years,and can develop into colorectal cancer in severe *** are currently no adequate or effective treatments for UC due to the fact that some patients have found suboptimal results after repeated administration,while others have experienced adverse *** the rapid development of nanotechnology,developing innovative colon-targeting platforms is essential to improving efficacy,reducing side effects,and improving patient *** this review,we summarize the pathophysiological characteristics of UC and the most recent status of numerous nanodrug delivery systems based on different targeting mechanisms in treating ***,intravenous,and rectal drug delivery nanoparticles targeting the colon are discussed,which can provide ideas for the design of colon-targeting nanoparticles for the treatment of colon diseases,especially for the treatment of *** but not least,we provide a glimpse into the future of colon-targeted delivery systems,as well as future advancements in the field.

关键词： Ulcerative colitis Physiological characteristics Colon-specific drug delivery Mechanisms of action Targeted therapy of UC

Unlocking the potential of amorphous calcium carbonate: A star ascending in the realm of biomedical application

在线全文

学校读者我要写书评

暂无评论

Acta Pharmaceutica Sinica B 2024年第2期14卷 602-622页

作者： han Liu Zhiyang Wen Zihan Liu Yanfang Yang Hongliang Wang Xuejun Xia Jun Ye yuling Liu State Key Laboratory of Bioactive Substance and Function of Natural Medicines Institute of Materia MedicaChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100050China Beijing Key Laboratory of Drug Delivery Technology and Novel Formulation Institute of Materia MedicaChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100050China

Calcium-based biomaterials have been intensively studied in the field of drug delivery owing to their excellent biocompatibility and ***-based materials can also deliver contrast agents,which can enhance real-time imaging and exert a Ca^(2+)-interfering therapeutic *** on these characteristics,amorphous calcium carbonate(ACC),as a brunch of calcium-based biomaterials,has the potential to become a widely used *** functional ACC can be either discovered in natural organisms or obtained by chemical synthesis However,the standalone presence of ACC is unstable in *** are required to be used as stabilizers or core-shell structures formed by permeable layers or lipids with modified molecules constructed to maintain the stability of ACC until the ACC carrier reaches its *** has high chemical instability and can produce biocompatible products when exposed to an acidic condition in vivo,such as Ca^(2+) with an immune-regulating ability and CO_(2) with an imaging-enhancing *** to these characteristics,ACC has been studied for selfsacrificing templates of carrier construction,targeted delivery of oncology drugs,immunomodulation,tumor imaging,tissue engineering,and calcium *** in this paper has been placed on the origin,structural features,and multiple applications of ***,ACC faces many challenges in clinical translation,and long-term basic research is required to overcome these *** hope that this study will contribute to future innovative research on ACC.

关键词： Amorphous calcium carbonate Drugdelivery system Nanoparticle Acid sensitivity Water instability,Tumortherapy Tissue engineering Calcium supplement

The cytosolic isoform of triosephosphate isomerase,ZmTPI4,is required for kernel development and starch synthesis in maize(Zea mays L.)

在线全文

学校读者我要写书评

暂无评论

The Crop Journal 2024年第2期12卷 401-410页

作者： Wenyu Li han Wang Qiuyue Xu Long Zhang Yan Wang Yongbiao Yu Xiangkun Guo Zhiwei Zhang Yongbin Dong yuling Li State Key Laboratory of Wheat and Maize Crop Science Collaborative Innovation Center of Henan Grain CropsCollege of AgronomyHenan Agricultural UniversityLongzi Lake CampusZhengzhou 450046HenanChina

Triosephosphate isomerase(TPI)is an enzyme that functions in plant energy production,accumulation,and *** understand its function in maize,we characterized a maize TPI mutant,*** comparison to the wild type,zmtpi4 mutants showed altered ear development,reduced kernel weight and starch content,modified starch granule morphology,and altered amylose and amylopectin ***,ATP,and pyruvate contents were reduced,indicating ZmTPI4 was involved in *** subcellular localization confirmed ZmTPI4 as a cytosolic rather than a plastid isoform of TPI,the zmtpi4 mutant showed reduced leaf size and chlorophyll *** of ZmTPI4 in Arabidopsis led to enlarged leaves and increased seed weight,suggesting a positive regulatory role of ZmTPI4 in kernel weight and starch *** conclude that ZmTPI4 functions in maize kernel development,starch synthesis,glycolysis,and photosynthesis.

关键词： Maize Kernel Starch Weight Photosynthesis