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Reproductive medicine gets a new tool

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Journal of Molecular Cell Biology 2011年第6期3卷 320-321页

作者： Wei-Xia ang cheng-Xu Delon Toh Huck-Hui Ng Yuin-Han Loh Epigenetics and Cell Fates Laboratory A*STAR Institute of Medical BiologySingapore 138648Singapore NUS Graduate School for Integrative Sciences and Engineering Singapore 117597Singapore Department of Biological Sciences National University of SingaporeSingapore 117543Singapore Gene Regulation Laboratory Genome Institute of SingaporeSingapore 138672Singapore Department of Biochemistry National University of SingaporeSingapore 117597Singapore School of Biological Sciences Nanyang Technological UniversitySingapore 639798Singapore

Infertility is a problem faced by millions *** a recent paper published in Cell,Hayashi et al.(2011)provided a potential solution for male infertility through the generation of functional spermatozoa that can give ris... 详细信息

关键词： infertility offspring

SCIRD: Revealing Infection of Malicious Software in Edge Computing-Enabled IoT Networks

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Computers, Materials & Continua 2024年第5期79卷 2743-2769页

作者： Jiehao Ye Wen cheng Xiaolong Liu Wenyi Zhu Xuan’ang Wu Shigen Shen School of Information Engineering Huzhou UniversityHuzhou313000China

The Internet of Things(IoT)has characteristics such as node mobility,node heterogeneity,link heterogeneity,and topology *** the face of the IoT characteristics and the explosive growth of IoT nodes,which brings about large-scale data processing requirements,edge computing architecture has become an emerging network architecture to support IoT applications due to its ability to provide powerful computing capabilities and good service ***,the defense mechanism of Edge Computing-enabled IoT Nodes(ECIoTNs)is still weak due to their limited resources,so that they are susceptible to malicious software spread,which can compromise data confidentiality and network service *** this situation,we put forward an epidemiology-based susceptible-curb-infectious-removed-dead(SCIRD)***,we analyze the dynamics of ECIoTNs with different infection levels under different initial conditions to obtain the dynamic differential ***,we establish the presence of equilibrium states in the SCIRD ***,we conduct an analysis of the model’s stability and examine the conditions under which malicious software will either spread or disappear within Edge Computing-enabled IoT(ECIoT)***,we validate the efficacy and superiority of the SCIRD model through MATLAB *** research findings offer a theoretical foundation for suppressing the propagation of malicious software in ECIoT *** experimental results indicate that the theoretical SCIRD model has instructive significance,deeply revealing the principles of malicious software propagation in ECIoT *** study solves a challenging security problem of ECIoT networks by determining the malicious software propagation threshold,which lays the foundation for buildingmore secure and reliable ECIoT networks.

关键词： Edge computing Internet of Things malicious software propagation model heterogeneity

Advances in cost-effective integrated spectrometers

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Light(Science & Applications) 2022年第7期11卷 1379-1396页

作者： ang Li Chunhui Yao Junfei Xia Huijie Wang Qixiang cheng Richard Penty Yeshaiahu Fainman Shilong Pan Key Laboratory of Radar Imaging and Microwave Photonics Ministry of EducationNanjing University of Aeronautics and AstronauticsNanjing 210016China Litin Technology XuzhouJiangsuChina Department of Engineering University of Cambridge9 JJ Thomson AvenueCambridge CB30FAUK Colllege of Automation Engineering Nanjing University of Aeronautics and AstronauticsNanjing 210016China Department of Electrical and Computer Engineering University of California at San DiegoLa JollaCAUSA

The proliferation of Internet-of-Things has promoted a wide variety of emerging applications that require compact,lightweight,and low-cost optical *** substantial progresses have been made in the miniaturization of spectrometers,most of them are with a major focus on the technical side but tend to feature a lower technology readiness level for *** importantly,in spite of the advancement in miniaturized spectrometers,their performance and the metrics of real-life applications have seldomly been connected but are highly *** review paper shows the market trend for chip-scale spectrometers and analyzes the key metrics that are required to adopt miniaturized spectrometers in real-life *** progress addressing the challenges of miniaturization of spectrometers is summarized,paying a special attention to the CMOS-compatible fabrication platform that shows a clear pathway to massive *** for ways forward are also presented.

关键词： cost summarized spite

Heuristic multistep attack scenarios construction based on kill chain

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The Journal of China Universities of Posts and Telecommunications 2023年第5期30卷 61-71页

作者： cheng Jie Zhang Ru Wei Jiahui Lu Chen Lü Zhishuai Lin Bingjie Xia ang State Grid Information and Telecommunication Branch Beijing 100761China School of Cyberspace Security Beijing University of Posts and TelecommunicationsBeijing 100876China

Network attacks evolved from single-step and simple attacks to complex multistep *** methods of multistep attack detection usually match multistep attacks from intrusion detection systems(IDS)alarms based on the correlation between attack ***,IDS has false negatives and false positives,which leads to incomplete or incorrect multistep *** based on simple similarity is difficult to obtain an accurate attack cluster,while association based on prior knowledge such as attack graphs is difficult to guarantee a complete attack knowledge *** solve the above problems,a heuristic multistep attack scenarios construction method based on the kill chain(HMASCKC)model was *** attack model graph can be obtained from dual data sources and heuristic multistep attack scenarios can be obtained through graph *** model graph of the attack and the predicted value of the next attack are obtained by calculating the matching *** according to the purpose of the multistep attack,the kill chain model is used to define the initial multistep attack model,which is used as the initial graph for graph *** results show that HMASCKC model can better fit the multistep attack behavior,the effect has some advantages over the longest common subsequence(LCS)algorithm,which can close to or match the prediction error of judge evaluation of attack intension(JEAN)*** method can make multistep attack model matching for unknown attacks,so it has some advantages in practical application.

关键词： multistep attack scenario kill chain graph matching attack prediction

Constructing a stable cobalt-nitrogen-carbon air cathode from coordinatively unsaturated zeolitic-imidazole frameworks for rechargeable zinc-air batteries

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Nano Research 2022年第7期15卷 5895-5901页

作者： Tingting Wang Meng Liu Somboon Chaemchuen Jichao Wang Ye Yuan cheng Chen ang Qiao Francis Verpoort Zongkui Kou State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of TechnologyWuhan 430070China

Zeolitic-imidazole frameworks(ZIFs)derivations have widely emerged as an efficient air cathode of zinc-air batteries(ZABs)due to excellent bifunctional oxygen electrocatalysis ***,they are not stable enough for long-term operation of rechargeable ZABs because of weak association with current collector,especially under bending conditions for flexible ZAB ***,we show that by purposely designing coordinatively unsaturated ZIFs via a facile morphology regulation,which can be chemically linked on acid-treated carbon cloth,a stable Co-N-C air cathode is therefore derived where Co nanoparticles(NPs)are uniformly confined within the Co-N-C matrix on carbon cloth(Co/Co-N-C/CC).Specifically,when without being stabilized from carbon cloth,the pyrolysis of ZIFs with different unsaturated coordination levels has a negligible impact on the bifunctional oxygen-catalyzed *** optimal Co/Co-N-C/CC catalyst assembled ZAB possesses a large open circuit voltage of 1.415 V and a high peak power density of 163 mW·cm^(−2) as well as excellent cycling durability upon 630 discharge–charge cycles with 61%voltage efficiency remained,largely exceeding those of a benchmark Pt/C-IrO_(2) catalyst assembled *** synergy between Co NPs and active Co-N-C sites via electronic interaction induces the outstanding bifunctional oxygen-catalyzed activity and cathode *** present work highlights the importance of unsaturated coordination structures in ZIFs precursors for the performance of derived nanostructures in integrated electrodes.

关键词： coordinatively unsaturated zeolitic-imidazole frameworks(ZIFs) cobalt-nitrogen-carbon bifunctional air electrodes zincair battery flexible electrode

Unified neutron star EOSs and neutron star structures in RMF models

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Communications in Theoretical Physics 2022年第9期74卷 105-119页

作者： cheng-Jun Xia Toshiki Maruyama ang Li Bao Yuan Sun Wen-Hui Long Ying-Xun Zhang Center for Gravitation and Cosmology College of Physical Science and TechnologyYangzhou UniversityYangzhou 225009China School of Information Science and Engineering NingboTech UniversityNingbo 315100China Advanced Science Research Center Japan Atomic Energy AgencyShirakata 2-4TokaiIbaraki 319-1195Japan Department of Astronomy Xiamen UniversityXiamen 361005China School of Nuclear Science and Technology Lanzhou UniversityLanzhou 730000China Frontiers Science Center for Rare Isotopes Lanzhou UniversityLanzhou 730000China China Institute of Atomic Energy Beijing 102413China Guangxi Key Laboratory Breeding Base of Nuclear Physics and Technology Guilin 541004China

In the framework of the Thomas-Fermi approximation,we systematically study the EOSs and microscopic structures of neutron star matter in a vast density range with n_(b)≈10^(-10)-2 fm^(-3),where various covariant density functionals are adopted,i.e.,those with nonlinear self couplings(NL3,PK1,TM1,GM1,MTVTC)and density-dependent couplings(DD-LZ1,DDME-X,PKDD,DDME2,DD2,TW99).It is found that the EOSs generally coincide with each other at nb■10^(-4)fm^(-3)and 0.1 fm^(-3)■n_(b)■0.3 fm^(-3),while in other density regions they are sensitive to the effective interactions between *** adopting functionals with a larger slope of symmetry energy L,the curvature parameter K_(sym)and neutron drip density generally increases,while the droplet size,proton number of nucleus,core-crust transition density,and onset density of non-spherical nuclei,*** functionals predict neutron stars with maximum masses exceeding the two-solar-mass limit,while those of DD2,DD-LZ1,DD-ME2,and DDME-X predict optimum neutron star radii according to the observational ***,the corresponding skewness coefficients J are much larger than expected,while only the functionals MTVTC and TW99 meet the start-of-art constraints on *** accurate measurements on the radius of PSR J0740+6620 and the maximum mass of neutron stars are thus essential to identify the functional that satisfies all constraints from nuclear physics and astrophysical *** linear correlations between neutron stars’radii at M=1.4M⊙and 2M⊙,the slope L and curvature parameter K_(sym)of symmetry energy are observed as well,which are mainly attributed to the curvature-slope correlations in the functionals adopted *** results presented here are applicable for investigations of the structures and evolutions of compact stars in a unified manner.

关键词： neutron star EOS nuclear pasta covariant density functionals

Progress and prospects in Mg-alloy super-sized high pressure die casting for automotive structural components

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Journal of Magnesium and Alloys 2023年第11期11卷 4166-4180页

作者： Tian Li Jiangfeng Song ang Zhang Guoqiang You Yan Yang Bin Jiang Xian Yue Qin cheng Xu Fushen Pan National Engineering Research Centre for Magnesium Alloys Chongqing UniversityChongqing400044PR China National Key Laboratory of Advanced Casting Technologies Chongqing UniversityChongqing400044PR China Boao Magnesium Aluminium Manufacturing Company Ltd Nantong TownWansheng Economic Development ZoneChongqing401120PR China Chongqing Millison Technologies Inc Banan DistrictChongqing401321PR China

Since the introduction of Tesla's Giga-Casting process, the automotive industry has widely accepted the concept of super-sized structural components due to their significant potential for enhancing the light-weighting of both electric and internal combustion engine *** super-sized components can be further lightened by using Mg alloys because of their exceptional lightweight characteristics, with a density only two-thirds that of aluminium alloys and one-fourth that of steel. This outstanding attribute offers the attractive prospect of achieving significant weight reduction without compromising structural integrity. This review examines studies on the Mg-alloy HighPressure Die Casting(HPDC) process, providing insights into the future prospects of incorporating Mg alloys into super-sized automotive HPDC components.

关键词： Mg alloy Giga-casting HPDC Super-sized

Gas metal arc welding of high nitrogen stainless steel with AreN_(2)-O_(2)ternary shielding gas

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Defence Technology（防务技术） 2021年第3期17卷 923-931页

作者： Zeng Liu cheng-lei Fan Zhu Ming Chao Chen ang Liu Chun-li Yang San-bao Lin Lang-ping Wang State Key Laboratory of Advanced Welding and Joining Harbin Institute of TechnologyHarbin150001China Inner Mongolia Metal Material Research Institute BaotouChina

High nitrogen stainless steel with nitrogen content of 0.75%was welded by gas metal arc welding with Ar-N_(2)-O_(2)ternary shielding *** effect of the ternary shielding gas on the retention and improvement of nitrogen content in the weld was *** test was conducted first to compare the ability of O_(2)and CO_(2)in prompting nitrogen *** nitrogen content of the surfacing metal with O_(2)is slightly higher than CO_(2).And then AreN_(2)-O_(2)shielding gas was applied to weld high nitrogen stainless *** using N_(2)-containing shielding gas,the nitrogen content of the weld was improved by 0.1 wt%.As N_(2)continued to increase,the increment of nitrogen content was not obvious,but the ferrite decreased from the top to the *** the proportion of N_(2)reached 20%,a full austenitic weld was obtained and the tensile strength was improved by 8.7%.Combined with the results of surfacing test and welding test,it is concluded that the main effect of N_(2)is to inhibit the escape of nitrogen and suppress the nitrogen diffusion from bottom to the top in the molten pool.

关键词： High nitrogen stainless steel AreN2-O2 shielding gas Action mechanism

Flexible polydimethylsiloxane pressure sensor with micro-pyramid structures and embedded silver nanowires:A novel application in urinary flow measurement

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Nanotechnology and Precision Engineering 2024年第3期7卷 1-12页

作者： Ben-Song Wang ang Gao Song-Wei Huang Qi-Hong Ning cheng Zhou Qi-Xiang Song Da-XiangCui School of Electronic Information and Electrical Engineering Shanghai Jiao Tong UniversityShanghai 200240China Department of Urology Renji HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai 200240China

Flexible pressure sensors are lightweight and highly sensitive,making them suitable for use in small portable devices to achieve precise measurements of tiny *** article introduces a low-cost and easy-fabrication strategy for piezoresistive flexible pressure *** embedding silver nanowires into a polydimethylsiloxane layer with micro-pyramids on its surface,a flexible pressure sensor is created that can detect low pressure (17.3 Pa) with fast response (<20 ms) and high sensitivity (69.6 mA kPa-1).Furthermore,the pressure sensor exhibits a sensitive and stable response to a small amount of water flowing on its *** this basis,the flexible pressure sensor is innovatively combined with a micro-rotor to fabricate a novel urinary flow-rate meter (uroflowmeter),and results from a simulated human urination experiment show that the uroflowmeter accurately captured all the essential shape characteristics that were present in the pump-simulated urination *** ahead,this research provides a new reference for using flexible pressure sensors in urinary flow-rate monitoring.

关键词： Flexible pressure sensor Silver nanowires Portable device Uroﬂowmeter Healthcare