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近红外漫射光层析成像实验研究

光子学报 2007年第6期36卷 1142-1146页

作者：赵会娟姜颖婷缪辉高峰 YUKARI Tanikawa yukio yamada 天津大学精密测试技术及仪器国家重点实验室天津300072 天津大学精密仪器与光电子工程学院生物医学工程系天津300072 National Institute of Advanced Industrial Science and Technology (AIST) 1-2 NamikiTsukuba Ibaraki 305-8564Japan National Institute of Advanced Industrial Science and Technology (AIST) 1-2 NamikiTsukuba Ibaraki 305-8564Japan University of Electro-Communications1-5-1 ChofugaokaChofuTokyo 182-8585Japan

实验验证了所建立的时间分辨光学层析成像测量系统的光学参量预测能力、多个测量通道的一致性,表明了本测量系统具有层析成像的潜力.研究了采用特征数据量(平均飞行时间、广义脉冲谱技术为基础的用数据类型R)及全时间分辨数据的图像重... 详细信息

实验验证了所建立的时间分辨光学层析成像测量系统的光学参量预测能力、多个测量通道的一致性,表明了本测量系统具有层析成像的潜力.研究了采用特征数据量(平均飞行时间、广义脉冲谱技术为基础的用数据类型R)及全时间分辨数据的图像重建算法在光学参量重建准确度、重建出的对象尺寸、空间分辨率等方面的各自优势.

关键词：医学成像近红外光时间分辨光学层析成像

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基于时间分辨测量的近红外光三维层析成像研究

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光子学报 2008年第8期37卷 1580-1584页

作者：赵会娟王召霞姜颖婷高峰 TANIKAWA Yukari yamada yukio 天津大学精密测试技术及仪器国家重点实验室天津300072 天津大学精密仪器与光电子工程学院生物医学工程系天津300072 National Institute of Advanced Industrial Science and Technology(AIST) 1-2 NamikiTsukubaIbaraki 305-8564Japan University of Electro-Communications 1-5-1 ChofugaokaChofuTokyo 182-8585Japan

针对近红外漫射光层析成像中的三维成像问题展开了理论和实验研究.利用开发的以强度和平均飞行时间作为数据类型的三维重建算法对数值仿真模型进行了重建,同时采用多通道时间相关单光子计数层析成像系统对固体样品进行了三维成像.结果表... 详细信息

针对近红外漫射光层析成像中的三维成像问题展开了理论和实验研究.利用开发的以强度和平均飞行时间作为数据类型的三维重建算法对数值仿真模型进行了重建,同时采用多通道时间相关单光子计数层析成像系统对固体样品进行了三维成像.结果表明:所发展的算法较忠实地重建出了样品内部的异质体结构;采用的差分重建方法有利于提高重建的抗噪性能;提出的单层测头配置模式对于三维成像具有实际意义.

关键词：近红外光时间分辨三维光学层析成像

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家禽科学对人类社会的贡献

中国畜牧兽医 1990年第1期 2-4页

作者： yukio yamada 蔡辉益

前言尽管目前对有关家禽起源的单一和多种品系学说仍有争议,但可以肯定野禽的驯化是在公元前大约6000年起源于东南亚。最近(1988)由West和Zhou报道的考古证据表明,在公元

关键词：家禽业孟德尔禽肉产量肉鸡业

Report for Type 2 Bayes-Fuzzy Estimation in No-Data Problem

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Applied Mathematics 2024年第1期15卷 46-50页

作者： Houju Hori Jr. Kazuhisa Takemura yukio Matsumoto Nara Cmmunity Tsubakikishi Shrine Nara Japan Department of Psychology Waseda University Tokyo Japan The Institute of Mathematical Statistics Tachikawa Japan

It is well known that the system (1 + 1) can be unequal to 2, because this system has both observation error and system error. Furthermore, we must provide our mustered service within our cool head and warm heart, where two states of nature are existing upon us. Any system is regarded as the two-dimensional variable error model. On the other hand, we consider that the fuzziness is existing in this system. Though we can usually obtain the fuzzy number from the possibility theory, it is not fuzzy but possibility, because the possibility function is as same as the likelihood function, and we can obtain the possibility measure by the maximal likelihood method (i.e. max product method proposed by Dr. Hideo Tanaka). Therefore, Fuzzy is regarded as the only one case according to Vague, which has both some state of nature in this world and another state of nature in the other world. Here, we can consider that Type 1 Vague Event in other world can be obtained by mapping and translating from Type 1 fuzzy Event in this world. We named this estimation as Type 1 Bayes-Fuzzy Estimation. When the Vague Events were abnormal (ex. under War), we need to consider that another world could exist around other world. In this case, we call it Type 2 Bayes-Fuzzy Estimation. Where Hori et al. constructed the stochastic different equation upon Type 1 Vague Events, along with the general following probabilistic introduction method from the single regression model, multi-regression model, AR model, Markov (decision) process, to the stochastic different equation. Furthermore, we showed that the system theory approach is Possibility Markov Process, and that the making decision approach is Sequential Bayes Estimation, too. After all, Type 1 Bays-Fuzzy estimation is the special case in Bayes estimation, because the pareto solutions can exist in two stochastic different equations upon Type 2 Vague Events, after we ignore one equation each other (note that this is Type 1 case), we can obtain both its

关键词： Bayes-Fuzzy Estimation Possibility Markov Process Possibility Reserved Judgement

Pulmonary artery diameter ratio as a prognostic indicator of congenital diaphragmatic hernia

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World Journal of Pediatric Surgery 2024年第1期7卷 20-25页

作者： Yuichiro Miyake Hiroyuki Koga Shuko Nojiri Shunsuke yamada Takanori Ochi Go Miyano Geoffrey J Lane Atsuyuki Yamataka Tadaharu Okazaki Department of Pediatric General and Urogenital Surgery Juntendo University School of MedicineBunkyo-kuTokyoJapan Department of Medical Technology Innovation Center Juntendo UniversityBunkyo-ku TokyoJapan Department of Pediatric Surgery Juntendo University Urayasu HospitalUrayasuChibaJapan

Background Following on from an earlier study published in 2008 about left pulmonary artery(LPA)flow measured on serial echocardiography being strongly prognostic in left-sided congenital diaphragmatic hernia(CDH)and the ratio of LPA to right pulmonary artery(RPA)diameters being a simple and reliable indicator for commencing nitric oxide(NO)therapy,the ratio of LPA:RPA diameters(PA ratio orPAR)was hypothesized to possibly reflect cardiopulmonary stresses accompanying CDH *** Subjects with isolated left-sided CDH treated between 2007 and 2020 at a single pediatric surgical center were recruited and classified according to *** obtained retrospectively for subject demographics,clinical course,LPA/RPA diameters,and PAR were compared between survivors and *** value of PAR for optimizing the prognostic value of PA diameter data in CDH were analyzed with receiver operating characteristic(ROC)curve *** Of 65 subjects,there were 54 survivors(82.3%)and 11 non-survivors(17.7%);7 of 11 non-survivors died before surgical repair could be *** PAR for survivors(0.851±0.152)was significantly higher than for non-survivors(0.672±0.108)(p=0.0003).Mean PAR for non-survivors was not affected by surgical *** of survivors were:LPA≥2 mm(n=52 of 54;mean PAR=0.866±0.146)and RPA≥3mm(n=46 of 54;mean PAR=0.857±0.152).Non-survivors with similar LPA and RPA diameters to survivors had significantly lower mean *** curve cut-off for PAR was *** with high PAR(≥0.762)required high-frequency oscillatory ventilation/NO less than subjects with low PAR(<0.762)(p=0.0244 and p=0.0485,respectively)and subjects with high PAR stabilized significantly earlier than subjects with low PAR(1.71±0.68 days vs 3.20±0.87 days)(p<0.0001).Conclusions PAR would appear to be strongly correlated with clinical outcome in CDH and be useful for planning management of cardiopulmonary instability in CDH.

关键词： hernia congenital diameters

Severe aconite poisoning successfully treated with veno-arterial extracorporeal membrane oxygenation:A case report

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World Journal of Clinical Cases 2024年第2期12卷 399-404页

作者： Saeko Kohara Yoshito Kamijo Ryoko Kyan Ichiro Okada Eiju Hasegawa Soichiro yamada Koichi Imai Asuka Kaizaki-Mitsumoto Satoshi Numazawa Department of Critical Care Medicine and Trauma National Hospital Organization Disaster Medical CenterTokyo 1900014Japan Department of Clinical Toxicology Saitama Medical UniversitySaitama 3500495Japan Saitama Prefectural Institute of Public Health Saitama Prefectural Institute of Public HealthSaitama 3550133Japan Division of Toxicology Department of PharmacologyToxicology and TherapeuticsShowa University School of PharmacyTokyo 1428555Japan

BACKGROUND Most species of aconite contain highly toxic aconitines,the oral ingestion of which can be fatal,primarily because they cause ventricular *** describe a case of severe aconite poisoning that was successfully treated through venoarterial extracorporeal membrane oxygenation(VA-ECMO)and in which detailed toxicological analyses of the aconite roots and biological samples were performed using liquid chromatography-tandem mass spectrometry(LC-MS/MS).CASE SUMMARY A 23-year-old male presented to the emergency room with circulatory collapse and ventricular arrhythmia after ingesting approximately half of a root labeled,“Aconitum japonicum Thunb”.Two hours after arrival,VA-ECMO was initiated as circulatory collapse became refractory to antiarrhythmics and *** hours after arrival,an electrocardiogram revealed a return to sinus *** patient was weaned off VA-ECMO and the ventilator on hospital days 3 and 5,*** hospital day 15,he was transferred to a psychiatric *** other half of the root and his biological samples were toxicologically analyzed using LC-MS/MS,revealing 244.3 mg/kg of aconitine and 24.7 mg/kg of mesaconitine in the *** on admission contained 1.50 ng/mL of *** hospital day 2,neither were *** on admission showed 149.09 ng/mL of aconitine and 3.59 ng/mL of mesaconitine,but these rapidly decreased after hospital day *** The key to saving the life of a patient with severe aconite poisoning is to introduce VA-ECMO as soon as possible.

关键词： Aconite poisoning Fatal arrhythmia Veno-arterial extracorporeal membrane oxygenation Aconitine Mesaconitine Case report

Excellentπ-Bowl Semiconductors Based on C_(70)Subunit

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CCS Chemistry 2024年第2期6卷 353-364页

作者： Meng Chen Yuxiao Duan Xinyue Liu Qian Zhan Hironobu Hayashi Kyohei Matsuo Hiroko yamada Guangpeng Gao Yonghao Zheng Lei Zhang Beijing Advanced Innovation Center for Soft Matter Science and Engineering Beijing University of Chemical TechnologyBeijing 100029 School of Optoelectronic Science and Engineering University of Electronic Science and Technology of China(UESTC)Chengdu 610054 Division of Materials Science Nara Institute of Science and Technology(NAIST)IkomaNara 630-0192 Key Laboratory of Cluster Science of Ministry of Education Beijing Key Laboratory of Photoelectronic/Electrophotonic Conversion MaterialsSchool of Chemistry and Chemical EngineeringBeijing Institute of TechnologyBeijing 100081

As open substructures of fullerenes,aromaticπ-bowls are promising candidates as new organic semiconductors,as well as attractive hosts for *** demonstrate herein the synthesis and characterization of a novel C_(2v)symmetricπ-bowl,pyracyleno[6,5,4,3,2,1-pqrstuv]pentaphene(3).Bowl 3 was equipped with two distinctive reactive sites,allowing for bromination and cross-coupling reactions to readily yield functionalized bowls with two 2,4,6-trimethylphenyl(5)and triethylsilyl(TES)-ethynyl(6)substituents,***-temperature 1H NMR analysis and density functional theory(DFT)calculations indicated bowl-to-bowl inversions of 3,5,and 6 at room *** alternating the substituents,the crystal structures of the threeπ-bowls 3,5,and 6 could be controlled from 1D linear to 1D slipped to 2D herringbone packing motifs,providing insight into the packing behavior ofπ-bowls.1H NMR titration study indicated that the TES-ethynyl substituent enhanced the ability ofπ-bowl to bind C_(70)with an association constant of 2485 M−*** C_(70)molecules withπ-bowls 3 and 6 formed 1:1 complexes,in which C_(70)molecules aggregated into zig-zag and 1D linear arrays,*** hole mobility of 2.3 cm^(2)V^(−1)^s(−1)and electron mobility of 0.16 cm^(2)V^(−1)^s(−1)ofπ-bowl 3 and its complex with C_(70)were demonstrated,respectively,which proved a great value for the development of aromaticπ-bowl semiconductors with tunable properties for organic electronic devices.

关键词： organic semiconductor π-bowl fullerene crystal engineering mobility

亚洲人光老化引起的皮肤泛黄与真皮羰基化之间的关系

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亚洲人光老化引起的皮肤泛黄与真皮羰基化之间的关系

Multiple esophageal variceal ruptures with massive ascites due to myelofibrosis-induced portal hypertension

第九届中国化妆品学术研讨会

作者：小仓由纪桑原智裕 Minoru Akiyama Shingo Tajima Kazuhisa Hattori Kouhei Okamoto Shinpei Okawa yukio yamada Hachiro Tagami Motoji Takahashi 平尾哲二资生堂研究中心防卫大学医学院皮肤病系电气通信大学东北大学医学院

光老化皮肤呈现出多种面貌特征如斑点、皱纹和下垂。在高龄人群,尤其是亚洲人,光老化皮肤伴随着一种皮肤颜色变黄的倾向。但是,对于这种老化面部皮肤的特殊颜色变化至今还没有过分析研究。目的:本研究的目的是研究真皮蛋白的羰基化是否... 详细信息

光老化皮肤呈现出多种面貌特征如斑点、皱纹和下垂。在高龄人群,尤其是亚洲人,光老化皮肤伴随着一种皮肤颜色变黄的倾向。但是,对于这种老化面部皮肤的特殊颜色变化至今还没有过分析研究。目的:本研究的目的是研究真皮蛋白的羰基化是否和光老化皮肤的黄色改变有关。方法:正常皮肤标本分别取自不同年代的日本人面部、腹部和臀部,并被分离成表皮和真皮两部分。对皮肤标本进行组织学检验。另外,应用丙烯醛或4-羟基壬烯酸(4-HNE,下同),在用胶原凝胶制作的真皮模型上也进行了实验。对所有的标本都进行了颜色测量。结果:光老化的面部皮肤表现出微黄的颜色,但是腹部和臀部标本无论是表皮还是真皮都没有表现出黄色。真皮上层出现了弹性纤维变性,用标记过的烟肼检测到弹性纤维与羰基化蛋白共存,同时用抗丙烯醛化合物抗体进行了免疫组织化学检测。实验性的使用丙烯醛或4-HNE诱导胶原凝胶发生羰基化反应,结果胶原凝胶也出现了黄色变,比色法测量的b*值升高,而且比糖基化的黄化更明显。结论:本试验有力的证实了真皮蛋白质的羰基化参与了光老化皮肤变黄的反应。

关键词：羰基化真皮弹性纤维面部黄色变

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World Journal of Gastroenterology 2012年第28期18卷 3770-3774页

作者： Koichi Tokai Hiroyuki Miyatani yukio Yoshida Shigeki yamada Department of Digestive Organs Jichi Medical University Saitama Medical Center Saitama 330-8503 Japan Department of Pathology Jichi Medical University Saitama Medical Center Saitama 330-8503 Japan

A 75-year old man had been diagnosed at 42 years of age as having polycythemia vera and had been monitored at another hospital. Progression of anemia had been recognized at about age 70 years, and the patient was thus referred to our center in 2008 where secondary myelofibrosis was diagnosed based on bone marrow biopsy findings. Hematemesis due to rupture of esophageal varices occurred in January and February of 2011. The bleeding was stopped by endoscopic variceal ligation. Furthermore, in March of the same year, hematemesis recurred and the patient was transported to our center. He was in irreversible hemorrhagic shock and died. The autopsy showed severe bone marrow fibrosis with mainly argyrophilic fibers, an observation consistent with myelofibrosis. The liver weighed 1856 g the spleen 1572 g, indicating marked hepatosplenomegaly. The liver and spleen both showed extramedullary hemopoiesis. Myelofibrosis is often complicated by portal hypertension and is occasionally associated with gastrointestinal hemorrhage due to esophageal varices. A patient diagnosed as having myelofibrosis needs to be screened for esophageal/gastric varices. Myelofibrosis has a poor prognosis. Therefore, it is necessary to carefully decide the therapeutic strategy in consideration of the patient's concomitant conditions, treatment invasiveness and quality of life.

关键词： Myelofibrosis Portal hypertension Rupture of esophageal varices