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Asian Journal of Urology 2023年第2期10卷 210-212页

作者： yuki kohada Hiroki Kusumoto Takashi Kukimoto Jotaro Mikami Jun Ito Katsutoshi Asano Toru Yaegashi Kanichi Nakagawara Jun Teishima Yasuhiro Kaiho Nobuyuki Hinata Yasuhiro Nakamura Makoto Sato Division of Urology Faculty of MedicineTohoku Medical and Pharmaceutical UniversitySendaiJapan Department of Urology Hiroshima University Graduate School of Biomedical SciencesHiroshimaJapan Nihon Gene Research Laboratories Inc SendaiJapan Division of Pathology Faculty of MedicineTohoku Medical and Pharmaceutical UniversitySendaiJapan

Dear Editor,Prostate cancer is the most common cancer among men[1].Androgen deprivation therapy(ADT)has remained the primary treatment of metastatic-hormone-sensitive prostate cancer(mHSPC),providing a temporary disease control in the majority of *** initial ADT response,castration-resistance prostate cancer(CRPC)still *** study have attempted to determine possible biomarkers for poor prognosis in patients with CRPC[2].

关键词： patients metastatic cancer

Current and future trends in whole genome sequencing in cancer

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Cancer Biology & Medicine 2024年第1期21卷 16-20页

作者： yuki Katsuya Department of Experimental Therapeutics National Cancer Center Hospital5-1-1 TsukijiChuo-kuTokyo 104-0045Japan

Cancer remains a formidable global health challenge affecting millions of lives *** decades,conventional cancer treatments used a one-size-fits-all approach,overlooking the intricate genetic variations that drive *** emergence of cancer genomics has ushered in a new era of personalized and targeted cancer *** Human Genome Project,which was launched in 1990 and completed in 2003。

关键词： cancer Cancer annually

Psychological potential field and human eye fixation on binary line-drawing images: A comparative experimental study

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Computational Visual Media 2020年第2期6卷 205-214页

作者： Naoyuki Awano yuki Hayashi Osaka University of Economics OsakaOsaka533-8533Japan Osaka Prefecture University SakaiOsaka599-8531Japan

Quantitatively evaluating the psychological and perceptual effects of objects is an important issue,but is difficult. In cognitive studies, the psychological potential field(PPF), which represents psychological intensities in vision and can be calculated by applying computational algorithms to digital images, may help with this issue. Although studies have reported using the PPF to evaluate psychological effects, such as impressions, detailed investigations on how the PPF represents psychological perception and its limitations have not yet been performed. Another relevant tool is the fixation map, which visualizes human eye fixations;this map is generated from actual measurements acquired by eye-tracking and does not represent psychological effects directly. Although the PPF and the fixation map are based on visual imaging, they have never been compared. In this paper, we do so for the first time, using psychological and perceptual properties of line-drawing images. The results demonstrate the difference between these methods, including their representation of different properties with respect to visual perception. Moreover, the similarity between the two methods highlights the possibility of assessing perceptual phenomena such as categorization and cognition of objects based on human vision.

关键词： psychological potential field(PPF) eye fixation eye-tracking visual perception line drawing

Regulation of Vascular Development by CLE Peptide-receptor Systems

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Journal of Integrative Plant Biology 2010年第1期52卷 8-16页

作者： yuki Hirakawa yuki Kondo Hiroo Fukuda Department of Biological Sciences Graduate School of ScienceThe University of Tokyo

Cell division and differentiation of stem cells are controlled by non- cell-autonomous signals in higher organisms. The plant vascular meristem is a stem-cell tissue comprising procambial cells that produce xylem cells on one side and phloem cells on the other side. Recent studies have revealed that TDIF （tracheary element differentiation inhibitory factor）/CLE41/CLE44 peptide signal controls the procambial cell fate in a non-cell-autonomous manner. TDIF produced in and secreted from phloem cells is perceived by TDR/PXY, a leucine-rich repeat receptor kinase located in the plasma membrane of procambial cells. This signal suppresses xylem cell differentiation of procambial cells and promotes their proliferation. In addition to TDIF, some other CLE peptides play roles in vascular development. Here, we summarize recent advances in CLE signaling governing vascular development.

关键词： TDIF Regulation of Vascular Development by CLE Peptide-receptor Systems

Visualization study on the coarse graining DEM for large-scale N gas-solid flow systems

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Particuology 2021年第6期19卷 24-33页

作者： yuki Mori Mikio Sakai Department of Nuclear Engineering and Management School of EngineeringThe University of Tokyo7-3-1 HongoBunkyo-kuTokyo 113-8656Japan Resilience Engineering Research Center School of EngineeringThe University of Tokyo7-3-1 HongoBunkyo-kuTokyo 113-8656Japan

Gas-solid flows are ubiquitous in industrial *** coupled model of the discrete element method(DEM)and computational fluid dynamics(CFD)is one of the techniques for the simulation of the gas-solid *** enhance the applicability of the DEM-CFD method,the coarse graining DEM has been developed to simulate large-scale powder *** coarse graining DEM is a scaling law model and hence can simulate large-scale systems using a smaller number of particles than the actual *** the coarse graining DEM enables to effectively simulate large-scale powder systems on a single PC,visualized image is lack of reality due to reduced spatial *** a novel visualization method is developed to produce realistic *** the proposed technique,the virtual particles are located by considering the motion and location of the coarse grain *** show the adequacy of the proposed method,two types of visualization based on the computational results are made:a blow-up of powder due to injected gas flow and a spouted *** these systems,the visualized images are shown to be improved by the proposed visualization *** effectiveness of the proposed method is proved by the agreement of the images based on the calculation results between the standard DEM-CFD method and coarse graining DEM.

关键词： DEM-CFD method Coarse graining DEM Computer graphics

Pseudogap,Fermi arc,and Peierls-insulating phase induced by 3D-2D crossover in monolayer VSe2

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Nano Research 2019年第1期12卷 165-169页

作者： yuki Umemoto Katsuaki Sugawara yuki Nakata Takashi Takahashi Takafumi Sato Department of Physics Tohoku UniversitySendai 980-8578Japan WPI-Advanced Institute for Materials Research Tohoku UniversitySendai 980-8577Japan Center for Spintronics Research Network Tohoku UniversitySendai 980-8577Japan

One of important challenges in condensed-matter physics is to realize new quantum states of matter by manipulating the dimensionality of materials,as represented by the discovery of high-temperature superconductivity in atomic-layer pnictides and room-temperature quantum Hall effect in *** sition-metal dichalcogenides(TMDs)provide a fertile platform for exploring novel quantum phenomena accompanied by the dimensionality change,since they exhibit a variety of electronic/magnetic states owing to quantum *** we report an anomalous metal-i nsulator transition in duced by three-dimensional(3D)-two-dimensional(2D)crossover in mono layer 1T-VSe2 grown on bilayer *** observed a complete insulating state with a finite energy gap on the entire Fermi surface in monolayer 1T-VSe2 at low temperatures,in sharp contrast to metallic nature of *** surprisingly,monolayer 1T-VSe2 exhibits a pseudogap with Fermi arc at temperatures above the charge-density-wave temperature,showing a close resemblanee to high-temperature *** similarity suggests a common underlying physics between two apparently different systems,pointing to the importance of charge/spin fluctuations to create the novel electronic states,such as pseudogap and Fermi arc,in these materials.

关键词： transition-metal dichalchogenides 1T-VSe2 charge density wave electronic states pseudogap Fermi arc

Optimization of body configuration and joint-driven attitude stabilization for transformable spacecraft under solar radiation pressure

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Astrodynamics 2024年第1期8卷 47-60页

作者： yuki Kubo Toshihiro Chujo Institute of Space and Astronautical Science Japan Aerospace Exploration AgencyKanagawa252-5210Japan Department of Mechanical Engineering Tokyo Institute of TechnologyTokyo152-8550Japan

The solar sail is one of the most promising space exploration systems due to its theoretically infinite specific impulse achieved through solar radiation pressure(SRP).Recently,researchers have proposed“transformable spacecraft”capable of actively reconfiguring their body configurations using actuatable *** spacecraft,if used similarly to solar sails,are expected to significantly enhance orbit and attitude control capabilities owing to their high redundancy in control degrees of ***,controlling them becomes challenging due to their large number of inputs,leading previous researchers to impose strong constraints to limit their potential control *** study focuses on novel attitude control techniques for transformable spacecraft under *** developed two methods,namely,joint angle optimization to obtain arbitrary SRP force and torque,and momentum damping control driven by joint angle *** proposed methods are formulated in a general manner and can be applied to any transformable spacecraft comprising front faces that can predominantly receive the SRP on each *** validity of our proposed method is confirmed through numerical *** study contributes to making most of the high control redundancy of transformable spacecraft without the need for expendable propellants,thus significantly enhancing the orbit and attitude control capabilities.

关键词： solar sail transformable spacecraft attitude-joint coupled motion attitudestabilization

Laser Interference Lithography for Fabrication of Planar Scale Gratings for Optical Metrology

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Nanomanufacturing and Metrology 2021年第1期4卷 3-27页

作者： yuki Shimizu Department of Finemechanics Tohoku University6-6-01Aramaki Aza-AobaAoba-kuSendaiMiyagi 980-8579Japan

Laser interference lithography is an attractive method for the fabrication of a large-area two-dimensional planar scale grating,which can be employed as a scale for multi-axis optical encoders or a diffractive optical element in many types of optical ***,optical configurations such as Lloyd's mirror interferometer based on the division of wavefront method can generate interference fringe fields for the patterning of grating pattern structures at a single exposure in a stable *** the fabrication of a two-dimensional scale grating to be used in a planar/surface encoder,an orthogonal two-axis Lloyd's mirror interferometer,which has been realized through innovation to Lloyd’s mirror interferometer,has been *** addition,the concept of the patterning of the two-dimensional orthogonal pattern structure at a single exposure has been extended to the non-orthogonal two-axis Lloyd’s mirror ***,the optical setup for the non-orthogonal two-axis Lloyd's mirror interferometer has been optimized for the fabrication of a large-area scale *** this review article,principles of generating interference fringe fields for the fabrication of a scale grating based on the interference lithography are reviewed,while focusing on the fabrication of a two-dimensional scale grating for planar/surface *** of the pitch of the fabricated pattern structures,whose accuracy strongly affects the performance of planar/surface encoders,is also an important task to be *** this paper,major methods for the evaluation of a grating pitch are also reviewed.

关键词： Planar scale grating Interference lithography Lloyd’s mirror interferometer Interference fringe

Development of a validation technique for road surface profile applicable to point cloud data

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Journal of Road Engineering 2022年第2期2卷 114-123页

作者： Kazuya Tomiyama yuki Yamaguchi Kazushi Moriishi yuki Kotani Division of Civil and Environmental Engineering Kitami Institute of TechnologyKitami 090-8507Japan Obayashi Road Corporation Tokyo 101-8228Japan Graduate School of Engineering Kitami Institute of TechnologyKitami 090-8507Japan

In recent years,various information and communication technology(ICT)devices measuring three-dimensional(3D)point cloud data have been developed and widely used for the application of pavement surface ***,ICT devices have generally been developed not only for measuring road surface profiles but for various geo-reference point *** this background,the validation of surface profiles acquired with ICT devices fulfils an important role in proving the reliability of measurement result composed by point *** study proposes a wavelet transform agreement(WTA)which involves a normalization factor of profile amplitude for further improvement in the wavelet-based coherence *** WTA analysis allows evaluating similarity/dissimilarity of two profiles considering both the location and wavelength *** this purpose,a terrestrial laser scanner(TLS),a mobile mapping system(MMS),and an unmanned aerial vehicle(UAV)are employed to prove the advantage of WTA in practical *** a result,the advantages of WTA analysis are clearly recognized in the optimization for the measurement interval of TLS,the multi-line measurement of MMS for ride quality improvement of a pavement,and the efficient operation of UAV in terms of the flight *** paper also shows the identification of aging development for surface roughness over time in terms of locations and *** findings help not only to guarantee the accuracy of profile measurements but to realize the sophisticated way of using 3D point clouds acquired with ICT *** outcomes of this study contribute to the increase of productivity for pavement works with improving the quality of surface profile measurement.

关键词： Surface profile Profile validation Point cloud Wavelet agreement Wavelet coherence

Life Cycle Assessment of Biodegradable Plastics

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Journal of Shanghai Jiaotong university(Science) 2012年第3期17卷 327-329页

作者： SAKAMOTO yuki Research Institute of Public Affairs Nara Sangyo UniversityNara 636-8503Japan

Many industrial products made from fossil fuels cause the problems of global warming,depletion of fossil fuel resources and decrease of the land by *** this report,the amounts of CO2 emissions as the environmental load and the specific energy consumptions as the depletion of fossil fuel resources of biodegradable plastics and conventional plastic as food trays are compared using life cycle assessment *** amount of CO2 emission of PHB(poly(3-hydroxybutyrate-co-4-hydroxybutyrate)) tray was the smallest among those of trays of other *** specific energy consumption of SPCL(starch/polycaprolactone) was the smallest among those of trays of other *** clearly reveals that the utilization of the biodegradable plastics is an effective way of alternatives of the conventional plastics.

关键词： life cycle assessment biodegradable plastics CO2 emission specific energy consumption