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Bioactive Materials 2020年第1期5卷 102-109页

作者： Yiqian Huang Zhaohui Huang Huanhuan Liu Xu Zhang Qing cai Xiaoping Yang State Key Laboratory of Organic-Inorganic Composites Beijing Laboratory of Biomedical MaterialsBeijing University of Chemical TechnologyBeijing100029China Department of Endodontics School and Hospital of StomatologyTianjin Medical UniversityTianjin300070China

Tissue engineering scaffolds made of conventional aliphatic polyesters are inherently non-fluorescent,which results in their in vivo degradation hard to be *** biodegradable polyorganophosphazenes(PPOPs)are synthesized by introducing fluorophores onto the polyphosphazene backbone via nucleophilic substitution *** this study,a fluorophore(termed as TPCA),derived from citric acid and 2-aminoethanethiol,was co-substituted with alanine ethyl ester onto the polyphosphazene backbone to obtain a photoluminescent biodegradable POPP(termed as PTA).The scaffolds made of PTA demonstrated non-cytotoxicity and cell affinity,particularly,capacity in promoting osteogenic differentiation of bone marrow mesenchymal stromal cells(BMSCs).In vivo evaluations using the rat calvarial defect model confirmed its strong potential in enhancing osteogenesis,more importantly,the in vivo degradation of the PTA scaffold could be monitored via its fluorescence intensity alongside implantation time.

关键词： Tissue regeneration Biodegradation Photoluminescent Polyorganophosphazene

Effects of combined spinal-epidural anesthesia on anxiety,labor analgesia and motor blocks in women during natural delivery

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World Journal of Psychiatry 2023年第11期13卷 838-847页

作者： Ling cai Jiao-Jiao Jiang Ting-Ting Wang Shuang Cao Department of Anesthesiology Shanghai Changning Maternity&Infant Health HospitalShanghai 200050China

BACKGROUND The background of this study was analgesia in natural *** combined spinal-epidural anesthesia has obvious analgesic effect on the parturients in natural labor,and combined spinal-epidural anesthesia has been widely used in anesthesia for various *** To study the effects of combined spinal-epidural anesthesia on anxiety,labor analgesia,and motor blocks in parturients during natural *** A total of 120 women who gave birth at Changning District Maternal and Child Health Hospital between December 2021 to December 2022 were included;a random number table approach was employed to divide the women into a control group and a joint group,with each group consisting of 60 *** control group was given epidural anesthesia,while the joint group was given combined spinal-epidural *** visual analog scale(VAS)was used to evaluate the degree of maternal *** were made between the two groups’conditions of childbirth and the duration of *** scores were used to evaluate the status of the newborns at birth;Self-rating Anxiety Scale(SAS)and General Self-Efficacy Scale(GSES)scores,umbilical artery blood gas analysis indices and stress indices were compared between the two groups;and the frequencies of motor block and postpartum complications were *** In comparison to the control group,in the joint group,the VAS scores for the first,second,and third stages of labor were lower(P0.05).The second and third stages of labor in the joint group were shorter than those in the control group(P<0.05).When compared to the control group,the postpartum SAS score of the joint group was lower,while the GSES score was g

关键词： Combined spinal-epidural anesthesia Natural delivery Anxiety level Labor analgesia Motor block

Endophytic Colletotrichum species from Bletilla ochracea (Orchidaceae), with descriptions of seven new speices

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Fungal Diversity 2013年第4期61卷 139-164页

作者： Gang Tao Zuo-Yi Liu Fang Liu Ya-Hui Gao Lei cai State Key Laboratory of Mycology Institute of MicrobiologyChinese Academy of SciencesBeijing 100101People’s Republic of China Guizhou Institute of Plant Protection Guiyang 550006People’s Republic of China Guizhou Key Laboratory of Agricultural Biotechnology Guiyang 550006People’s Republic of China

Thirty-six strains of endophytic Colletotrichum species were isolated from leaves of Bletilla ochracea Schltr.(Orchidaceae)collected from 5 sites in Guizhou,*** different species,including 7 new species(namely ***,***,***,***,***-altitudum and *** and ***),8 previously described species(***,***,***,***,***,***,*** and ***)and 2 sterile mycelia were *** of the taxa were identified based on morphology and phylogeny inferred from multi-locus sequences,including the nuclear ribosomal internal transcribed spacer(ITS)region,partial genes ofβ-tubulin(TUB2),actin(ACT)and glyceraldehyde-3-phosphate dehydrogenase(GAPDH).Comprehensive morphological descriptions and illustrations are provided for new *** investigation indicates a high diversity of Colletotrichum species in ***.

关键词： Fungal diversity Phylogeny Systematics Taxonomy

Tumor-associated macrophages in liver cancer:From mechanisms to therapy

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Cancer Communications 2022年第11期42卷 1112-1140页

作者： Kun Cheng Ning cai Jinghan Zhu Xing Yang Huifang Liang Wanguang Zhang Hepatic Surgery Centre Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei 430030P.R.China

Multidimensional analyses have demonstrated the presence of a unique tumor microenvironment(TME)in liver ***-associated macrophages(TAMs)are among the most abundant immune cells infiltrating the TME and are present at all stages of liver cancer progression,and targeting TAMs has become one of the most favored immunotherapy *** addition,macrophages and liver cancer cells have distinct *** the early stage of liver cancer,macrophages can provide a niche for the maintenance of liver cancer stem *** contrast,cancer stem cells(CSCs)or poorly differentiated tumor cells are key factors modulating macrophage *** the present review,we first propose the origin connection between precursor macrophages and liver cancer *** undergo dynamic phenotypic transition during *** this course of such transition,it is critical to determine the appropriate timing for therapy and block specific markers to suppress protumoral *** present review provides a more detailed discussion of transition trends of such surface markers than previous *** crosstalk occurs between TAMs and liver cancer *** play indispensable roles in tumor progression,angiogenesis,and autophagy due to their heterogeneity and robust *** addition,macrophages in the TME interact with other immune cells by directing cell-to-cell contact or secreting various effector ***,tumor cells combined with other immune cells can drive macrophage recruitment and *** the latest achievements and the advancements in treatment strategies following TAMs studies,comprehensive discussions on the communication between macrophages and cancer cells or immune cells in liver cancer are currently *** this review,we discussed the interactions between TAMs and liver cancer cells(from cell origin to maturation),the latest therapeutic strategies(including chimeric antigen receptor macrophages),and critical clinical

关键词： hepatocellular carcinoma intrahepatic cholangiocarcinoma tumor-associated macrophages immunotherapy

Effect of precise nursing service mode on postoperative urinary incontinence prevention in patients with prostate disease

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World Journal of Clinical Cases 2022年第5期10卷 1517-1526页

作者： Xi-Chun Zheng Ting-Ting Luo Dan-Dan Cao Wen-Zhi cai Department of Urology Shenzhen Hospital of Southern Medical UniversityShenzhen 518000Guangdong ProvinceChina Nursing Department Southern Medical UniversityShenzhen 518000Guangdong ProvinceChina

BACKGROUND Patients with benign prostatic disease often experience detrusor morphological changes and *** severe cases,it leads to bladder detrusor dysfunction,resulting in dysuria,frequent urination,urgent urination,incomplete urination,and other symptoms including renal function *** operation to restore normal urination function and to control postoperative complications,as far as possible,is the most common method for benign prostatic *** To observe the effect of precise nursing service mode on postoperative urinary incontinence prevention in patients with prostate *** In total,130 patients diagnosed with benign prostatic disease,from January 2018 to June 2021,in our hospital,were selected and divided into observation and control groups according to their treatment ***-five cases in the control group were given routine nursing mode intervention and 65 cases in the observation group received precise nursing service mode *** intervention with the observation group included psychological counseling about negative emotions,pelvic floor exercises,and post-hospital discharge *** complications of the two groups were counted,and the general postoperative conditions of the two groups were *** urinary flow dynamics indexes of the two groups were detected,and differences in clinical international prostate system score(IPSS)and urinary incontinence quality of life questionnaire(I-QOL)scores were *** Postoperative exhaust time(18.65±3.23 h and 24.63±4.51 h),the time of indwelling catheter(4.85±1.08 d and 5.63±1.24 d),and hospitalization time(8.78±2.03 d and 10.23±2.28 d)in the observation group were lower than in the control *** difference was statistically significant(P0.05)co

关键词： Precise nursing service mode Prostate disease Urinary incontinence Urodynamics Life quality

Decentralized model predictive control of nonlinear continuous systems with contractive constraints

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Decentralized model predictive control of nonlinear continuo...

CEPC positron source design

第25届中国控制与决策会议

作者： Xing cai Lei Xie Pei Sun Dept. of Control Science and Engineering Zhejiang University

ISBN: (纸本)9781467355339

This paper proposes a novel stabilizing decentralized model predictive control for nonlinear continuous *** extend the method proposed by [1] from nonlinear discrete time systems to nonlinear continuous systems. The key idea of this method is adding a contractive constraint to the optimal control problem of each *** adding the contractive constraint the whole system can be stabilizable within certain degree of interaction. The degree of the interaction is also represented by inequalities. Finally a numerical simulation is used to prove the effectiveness of the method and the method is also applied to a four-tank benchmark problem.

关键词： Decentralized model predictive control contractive constraint nonlinear continuous systems

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Radiation Detection Technology and Methods 2019年第3期3卷 120-126页

作者： cai Meng Xiaoping Li Guoxi Pei Jingru Zhang Key Laboratory of Particle Acceleration Physics and Technology Institute of High Energy PhysicsChinese Academy of SciencesBeijingChina

Purpose Circular Electron Positron Collider(CEPC)is a 100-km-ring e+e−collider for a Higgs *** injector is composed of a 10-GeV Linac and a 120-GeV *** CEPC Linac is a normal conducting S-band Linac with frequency of 2860 MHz providing electron and positron beams at an energy up to 10 GeV with 100 Hz repetition *** positron source is the most important part of the CEPC Linac,and the bunch charge of positron beam within some cut-off condition should be larger than 3 *** The positron source of CEPC is composed of a target,a flux concentrator,a capture section,a pre-accelerating section and a beam separation *** positron yield and capture efficiency are the design *** on simulation,the design will be presented and discussed in *** The positron yield at the PSPAS exit is larger than 0.55,and the normalized rms emittance is 2370 mm-mrad with a strict cut-off *** detailed simulation results will be *** The design of the positron source including positron production and capture will be presented and can meet the requirements.

关键词： Positron source CEPC Linac AMD Emittance

Stochastic observer design for Markovian jump one-sided Lipschitz systems with partly unknown transition rates 36

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Stochastic observer design for Markovian jump one-sided Lips...

High-density oxygen-doped nano-TaN enables robust polysulfide interconversion in Li−S batteries

第36届中国控制会议

作者： Shangwen Xia Shaohua Ma Zhiyuan cai Zhifeng Zhang School of Electrical Engineering Shenyang University of Technology

ISBN: (纸本)9781538629185

This paper deals with the stochastic observer design problem for the Markovian jump one-sided Lipschitz system with partly unknown transition rates. Firstly, the definitions as well as properties of one-sided Lipschitz function are ***, the observer is constructed for the system by Luenberger observer theory and the existence condition of the observer is derived by linear matrix inequality technique. Finally, two numerical examples are simulated to verify the effectiveness of the proposed method in this paper.

关键词： Stochastic observer One-sided Lipschitz systems Markovian jump Partly unknown transition rates

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Chinese Chemical Letters 2023年第8期34卷 360-364页

作者： Shuang Yu Yonggui Zhang Shuo Yang Kuikui Xiao Dong cai Huagui Nie Zhi Yang Key Laboratory of Carbon Materials of Zhejiang Province Wenzhou UniversityWenzhou 325035China College of Electrical and Electronic Engineering Wenzhou UniversityWenzhou 325035China

To tackle undesirable shuttle reaction and sluggish reaction kinetics in lithium–sulfur(Li–S)batteries,we develop a porous and high-density oxygen-doped tantalum nitride nanostructure(nano-TaNO)as an efficient catalyst through delicate *** from well-defined interior and surface nanopore channels,the nano-TaNO favors abundant sulfur storage,easy electrolyte infiltration and good electrons/Li+*** importantly,high-density O dopant in nano-TaNO not only provides high conductivity,but also promotes polysulfide adsorption/conversion via Li–O chemical interactions and the generation of S3∗−radicals to activate additional evolution path from S8 to Li_(2)***,the nano-TaNObased cathode exhibits excellent specific capacity and cyclability even under high sulfur loading *** interesting findings suggest the great potential of tantalum nitride and a high amount of anion doping engineering in manipulating intermediates and building high-performance Li−S rechargeable batteries.

关键词： Lithium−sulfur batteries Polysulfide conversion O doping TaN High-density

Difference between focal mechanisms of Dayao earthquake doublet sequence

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Earthquake Science 2009年第6期22卷 667-673页

作者： Xiaoshan Wang Xiangdong Feng Guiling Diao Libing Wang Lingling cai Earthquake Administration of Hebei Province Shijiazhuang 050021 China Hongshan Benchmark Seismic Station Longyao 055350 China

Using the maximum amplitude ratios of vertical component of P and S waves recorded by a regional network, 921 focal mechanisms of Dayao earthquake doublet sequence are determined by means of synthetic seismograms of a point source of dislocation in a plane layered medium. Among them, 389 focal mechanisms are in the aftershock sequence of M6.2 earthquake occurred on 21 July, 2003 and the other 532 focal mechanisms are in the aftershock sequence of M6.1 earthquake occurred on 16 October, 2003 in Dayao, Yurman. The focal mechanism consistent parameter a of the two aftershock sequences are calculated and analyzed. According to the focal mechanism consistent parameter a, the focal mechanisms of the first aftershock sequence are more consistent than those of the second. According to the comparison of CMT solutions of the two M6 earthquakes, the physical mechanism of the doublet in the intra-plate earthquake is very complex, and many processes are involved and interacted with each other. This doublet provides insights into earthquake clustering, triggering and stress cycling.

关键词： focal mechanism consistent parameter a Dayao earthquake doublet difference