检索结果-南通市图书馆

Characteristics and sources of peroxyacetyl nitrate(PAN)in the rural North China Plain:Results from1-year continuous observations

引用

Journal of Environmental Sciences 2024年第4期138卷 719-731页

作者： Xin Liu Xiaowei He Chenglong Zhang Yifei Song Shuyang Xie Chengtang Liu Pengfei Liu Yuanyuan Zhang yujing mu Junfeng Liu Research Center for Eco-Environmental Sciences Chinese Academy of SciencesBeijing 100085China University of Chinese Academy of Sciences Beijing 100049China

Peroxyacetyl nitrate(PAN)is an important photochemical pollutant in the troposphere,whereas long-term measurements are scarce in rural areas in North China Plain(NCP),resulting in unclear seasonal variations and sources of PAN in rural *** this study,we conducted a 1-year observation of PAN during 2021-2022 at the rural NCP *** average concentrations of PAN were 1.10,0.75,0.65,and 0.88 ppbv in spring,summer,autumn,and winter,respectively,with a 1-year average of 0.81±0.60 *** indicate that the loss of PAN through thermal decomposition in summer accounts for 43.2% of the total formed PAN,which is an important reason for the low concentration of PAN in *** speculate that since the correlation between PAN and O_(3) in winter is significantly lower than that in other seasons,the observed regional transport of PAN cannot be ignored in *** budget analysis,regional transport accounted for 12.8% and 55.9% of the observed PAN on the spring and winter pollution days,respectively,which showed that regional transport played key roles during the photochemical pollution of the rural NCP in *** potential source contribution function revealed that the transported PAN mainly comes from southern Hebei in *** winter,the transported PAN was mainly from Langfang,Hengshui,and southern *** findings may aid in understanding PAN variations in different seasons in rural areas and highlight the impact of regional transport on the PAN budget.

关键词： Photochemical pollution Peroxyacetyl nitrate(PAN) Seasonal variations Regional transport Rural area

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A study on wildfire impacts on greenhouse gas emissions and regional air quality in South of Orléans,France

引用

Journal of Environmental Sciences 2024年第1期135卷 521-533页

作者： Chaoyang Xue Gisèle Krysztofiak Yangang Ren Min Cai Patrick Mercier Frédéric Le Fur Corinne Robin Benoit Grosselin Véronique Daele Max RMcGillen yujing mu Valéry Catoire Abdelwahid Mellouki Laboratoire de Physique et Chimie de l’Environnement et de l’Espace(LPC2E) CNRS–UniversitéOrléans–CNES(UMR 7328)Orléans Cedex 245071France Institut de Combustion AérothermiqueRéactivitéEnvironnement(ICARE)CNRSOrléans Cedex 245071France Research Centre for Eco-Environmental Sciences Chinese Academy of SciencesBeijing 100085China Lig’Air-Association de surveillance de la qualitéde l’air en région Centre-Val de Loire Saint-Cyr-en-Val 45590France Mohammed V University RabatMorocco

Wildfire events are increasing globally which may be partly associated with climate change,resulting in significant adverse impacts on local,regional air quality and global *** September 2020,a small wildfire(burned area:36.3 ha)event occurred in Souesmes(Loiret-Cher,Sologne,France),and its plume spread out over 200 km on the following day as observed by the MODIS *** on measurements at a suburban site(~50 km northwest of the fire location)in Orléans and backward trajectory analysis,young wildfire plumes were *** increases in gaseous pollutants(CO,CH_(4),N_(2)O,VOCs,etc.)and particles(including black carbon)were found within the wildfire plumes,leading to a reduced air *** factors,defined as EF(X)=ΔX/ΔCO(where,X represents the target species),of various trace gases and black carbon within the young wildfire plumes were determined accordingly and compared with previous *** in the ambient ions(such as ammonium,sulfate,nitrate,chloride,and nitrite in the particle-and gasphase)and aerosol properties(e.g.,aerosol water content,aerosol p H)were also quantified and ***,we estimated the total carbon and climate-related species(e.g.,CO_(2),CH_(4),N_(2)O,and BC)emissions and compared them with fire emission *** biomass burning emission inventories have uncertainties in estimating small fire burned areas and *** instance,we found that the Global Fire Assimilation System(GFAS)may underestimate emissions(e.g.,CO)of this small wildfire while other inventories(GFED and FINN)showed significant *** that it is the first time to record wildfire plumes in this region,related atmospheric implications are presented and discussed.

关键词： Wildfire Air quality Emission factor Emission inventory VOLTAIRE supersite

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

骨骼肌再生过程中卫星细胞调控机制及其生态位信号的作用

引用

中国组织工程研究 2024年第7期28卷 1105-1111页

作者：孔健达穆玉晶朱磊李志林陈世娟曲阜师范大学体育科学学院山东省济宁市273100 北京中医药大学东直门医院北京市100010 天津师范大学体育科学学院天津市300380

背景:卫星细胞是骨骼肌包含的一种特定的成体干细胞群,可促进损伤骨骼肌的再生重建,但其具体机制尚不完善。目的:综述骨骼肌再生过程中卫星细胞调控作用以及卫星细胞与其生态位信号相互作用的机制,旨在总结现有知识的基础上提供新的研... 详细信息

背景:卫星细胞是骨骼肌包含的一种特定的成体干细胞群,可促进损伤骨骼肌的再生重建,但其具体机制尚不完善。目的:综述骨骼肌再生过程中卫星细胞调控作用以及卫星细胞与其生态位信号相互作用的机制,旨在总结现有知识的基础上提供新的研究思路和角度。方法:检索Web of Science、PubMed、中国知网(CNKI)、万方、维普等数据库2002年1月至2022年6月发表的文献。英文检索词:muscle,skeletal muscle,muscle injury,stem cells,satellite cells,muscle repair等;中文检索词:骨骼肌,骨骼肌再生,骨骼肌重建,卫星细胞,生态位等。共纳入66篇文献进行整理和分析。结果与结论:(1)卫星细胞存在于骨骼肌中,其既有助于损伤后新肌纤维的形成,亦有助于已存在的成年肌纤维有效生长。(2)卫星细胞中的静止卫星细胞被激活后,骨骼肌再生过程中卫星细胞的增殖、分化和融合形成肌纤维等步骤均会受到其内在不同机制调控作用的影响。(3)卫星细胞可与所处生态位信号中的肌纤维、细胞外基质、骨骼肌交界位、纤维生成祖细胞、免疫细胞以及内皮细胞相互作用促进卫星细胞的激活和增殖和分化,进而实现骨骼肌的有效再生。(4)未来研究可能的突破口:机体内卫星细胞的分裂模式;调控卫星细胞转移相关机制;卫星细胞在体内分化或自我更新的具体时间;卫星细胞和骨骼肌交界位的相互作用机制。(5)此次综述可为骨骼肌损伤重建的领域及其创新提供一定的理论参考价值。

关键词：骨骼肌骨骼肌再生卫星细胞调控生态位信号

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

CDK4/6抑制剂联合内分泌疗法治疗HR+/HER2-乳腺癌疗效和安全性的Meta分析

引用

中国循证医学杂志 2024年第3期24卷 280-287页

作者：穆玉晶冯雪孔健达左禧萌汪唐顺史晓光北京中医药大学东直门医院普外科北京100007 曲阜师范大学体育科学学院山东济宁273100

目的系统评价CDK4/6抑制剂联合内分泌疗法治疗HR+/HER2-乳腺癌的疗效和安全性。方法计算机检索PubMed、Cochrane Library、Web of Science、WanFang Data和CNKI数据库以及美国临床肿瘤学会(ASCO)、欧洲医学肿瘤学会(ESMO)和圣安东尼奥... 详细信息

目的系统评价CDK4/6抑制剂联合内分泌疗法治疗HR+/HER2-乳腺癌的疗效和安全性。方法计算机检索PubMed、Cochrane Library、Web of Science、WanFang Data和CNKI数据库以及美国临床肿瘤学会(ASCO)、欧洲医学肿瘤学会(ESMO)和圣安东尼奥乳腺癌研讨会(SABCS)网站,搜集有关CDK4/6抑制剂联合内分泌疗法治疗HR+/HER2-乳腺癌的随机对照试验,检索时限均从建库至2023年7月5日。由2位研究者独立筛选文献、提取资料并评价纳入研究的偏倚风险后,采用RevMan 5.4和Stata 14.0软件进行Meta分析。结果共纳入8个研究,包括4580例患者。Meta分析结果显示:联合治疗组患者的总生存期和无进展生存期明显长于单独内分泌治疗组[HR=0.80,95%CI(0.73,0.89),P<0.05;HR=0.54,95%CI(0.50,0.59),P<0.05]。联合治疗组患者的客观缓解率和临床获益率高于单独内分泌治疗组[RR=1.47,95%CI(1.34,1.62),P<0.05;RR=1.20,95%CI(1.11,1.30),P<0.05]。此外,联合治疗组的中性粒细胞减少、白细胞减少等血液毒性事件的发生率更高,但恶心、腹泻及头痛等不良反应发生率两组差异均无统计学意义。结论CDK4/6抑制剂联合内分泌疗法治疗HR+/HER2-乳腺癌患者可提高总生存期、无进展生存期、临床获益率及客观缓解率,具有显著的远期及近期疗效;但该方案使部分不良反应的发生率升高,临床用药需警惕严重不良反应的发生。

关键词： CDK4/6抑制剂内分泌治疗 HR+/HER2-乳腺癌系统评价 Meta分析随机对照试验

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

基于CiteSpace分析我国中医药领域乳腺癌治疗的研究热点及趋势

引用

实用中医内科杂志 2024年第4期38卷 80-83,I0009-I0011页

作者：穆玉晶孔健达汪唐顺北京中医药大学东直门医院北京100700 曲阜师范大学体育科学学院山东曲阜273100

目的利用CiteSpace 5.8软件分析中国中医药领域乳腺癌治疗近20年来的研究热点和趋势,探究其未来发展方向。方法在中国期刊网数据库(CNKI)中对2000年1月—2022年4月的中医药领域乳腺癌治疗文献进行检索,以“乳腺癌”和“中医药”为主题,... 详细信息

目的利用CiteSpace 5.8软件分析中国中医药领域乳腺癌治疗近20年来的研究热点和趋势,探究其未来发展方向。方法在中国期刊网数据库(CNKI)中对2000年1月—2022年4月的中医药领域乳腺癌治疗文献进行检索,以“乳腺癌”和“中医药”为主题,导入NoteExpress软件,然后根据纳入和排除标准进行人工检索,以Refworks格式导入CiteSpace 5.8软件,以该软件来可视化分析纳入文献的作者、机构、关键词及其他信息。结果共收录2207篇论文,文献数量总体呈现出上升趋势,核心作者58人,发文最多的作者为刘胜,作者团队内部合作较稳定,但团队之间合作较少。研究机构主要在中医药类高校,各机构间联系相对紧密,呈现出一定地域性。相关关键词主要为化疗、生活质量、中药、凋亡等,关键词聚类共有95个,前十个聚类涵盖临床试验、动物实验和机制研究以及药物实验,关键词凸现前18个关键词表明,最近的研究热点集中在“免疫功能”“疗效”“自噬”方面。结论中医药领域乳腺癌治疗的相关研究成果丰富而广泛,研究热点主要集中在中医药应用提高乳腺癌患者的生活质量、提高免疫功能、辅助化疗和细胞凋亡机制。而细胞自噬和免疫功能的研究为近年来的研究前沿,这为该领域未来研究提供了方向,但仍需要更多高质量研究支持。

关键词：乳腺癌中医药可视化分析 CiteSpace 知识图谱

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A critical review of sulfate aerosol formation mechanisms during winter polluted periods

引用

Journal of Environmental Sciences 2023年第1期123卷 387-399页

作者： Can Ye Keding Lu Huan Song yujing mu Jianmin Chen Yuanhang Zhang State Key Joint Laboratory of Environmental Simulation and Pollution Control College of Environmental Sciences and EngineeringPeking UniversityBeijing 100871China Research Center for Eco-Environmental Sciences Chinese Academy of SciencesBeijing 100085China Shanghai Key Laboratory of Atmospheric Particle Pollution and Prevention Department of Environmental Science and EngineeringInstitute of Atmospheric SciencesFudan UniversityShanghai 200438China

Sulfate aerosol contributes to particulate matter pollution and plays a key role in aerosol radiative forcing,impacting human health and climate *** models tend to substantially underestimate sulfate concentrations during haze episodes,indicating that there are still missing mechanisms not considered by the *** recent good progress in understanding the missing sulfate sources,knowledge on different sulfate formation pathways during polluted periods still involves large uncertainties and the dominant mechanism is under heated debate,calling for more field,laboratory,and modeling ***,we review the traditional sulfate formation mechanisms in cloud water and also discuss the potential factors affecting multiphase S(Ⅳ)*** recent progress in multiphase S(Ⅳ)oxidation mechanisms is *** formation rates by different prevailing oxidation pathways under typical winter-haze conditions are also calculated and *** on the literature reviewed,we put forward control of the atmospheric oxidation capacity as a means to abate sulfate aerosol ***,we conclude with a concise set of research priorities for improving our understanding of sulfate formation mechanisms during polluted periods.

关键词： Sulfate aerosol Formation mechanisms multiphase oxidation Transition metal ions Reactive oxygen species

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Significant emission reductions of carbonaceous aerosols from residential coal burning by a novel stove

引用

Journal of Environmental Sciences 2022年第10期34卷 135-143页

作者： Xuran Li Chenglong Zhang Weimin Zhuo Yuxuan Zhuo Jincheng Yang Min Song yujing mu Research Center for Eco-Environmenta1l Sciences Chinese Academy of SciencesBeijing 100085China University of Chinese Academy of Sciences Beijing 100049China Center for Excellence in Urban Atmospheric Environment Institute of Urban EnvironmentChinese Academy of SciencesXiamen 361021China Xuzhou Zhongkai Mechanical&Electrical Equipment Manufacturing Co. Ltd.Xuzhou 221300China School of Environmental Science and Engineering Shandong UniversityJinan 250100China

Carbonaceous aerosols(CA) are crucial components in the atmospheric PM_(2.5) and derived from diverse sources. One of the major sources for CA is from the incomplete combustion of bituminous coal that has been prevailingly used by household stoves in rural areas for heating during winter. To efficiently eliminate the CA emission, a new household stove(NHS) was developed based on a novel combustion technology and CA emissions from the NHS and a traditional household stove(THS) were comparably investigated under the actual stove operation conditions in a farmer’s house. Compared with the THS, the emission factors of organic carbon(OC), elemental carbon(EC), and water-soluble organic carbon(WSOC) from the NHS were reduced by 96%±1%, 98%±1%, and 91%±1% under the flaming process and 95%±1%, 96%±2%, and 83%±4% under the smoldering process, respectively. Additionally,the mass absorption efficiency of WSOC from the NHS reduced by 3 folds and the radiative forcing by WSOC relative to EC shrank remarkably by a factor of 3-8. Based on the reduction of emissions and light absorption of WSOC, the promotion of the NHS offers a possible solution to achieve the clean combustion of residential solid fuel.

关键词： OC EC WSOC Emission factor Light absorption

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Rural vehicle emission as an important driver for the variations of summertime tropospheric ozone in the Beijing-Tianjin-Hebei region during 2014-2019

引用

Journal of Environmental Sciences 2022年第4期34卷 126-135页

作者： Yifei Song Yuanyuan Zhang Junfeng Liu Chenglong Zhang Chengtang Liu Pengfei Liu yujing mu Research Center for Eco-Environmental Sciences Chinese Academy of SciencesBeijing 100085China Center for Excellence in Urban Atmospheric Environment Institute of Urban EnvironmentChinese Academy of SciencesXiamen 361021China University of Chinese Academy of Sciences Beijing 100049China

Tropospheric ozone(O_(3))pollution is increasing in the Beijing-Tianjin-Hebei(BTH)region despite a significant decline in atmospheric fine aerosol particles(PM_(2.5))in recent ***,the intrinsic reason for the elevation of the regional O_(3)is still *** this study,we analyzed the spatio-temporal variations of tropospheric O_(3)and relevant pollutants(PM_(2.5),NO_(2),and CO)in the BTH region based on monitoring data from the China Ministry of Ecology and Environment during the period of *** results showed that summertime O_(3)concentrations were constant in Beijing(BJ,0.06μg/(m^(3)·year))but increased significantly in Tianjin(TJ,9.09μg/(m^(3)·year))and Hebei(HB,6.06μg/(m3·year)).Distinct O_(3)trends between Beijing and other cities in BTH could not be attributed to the significant decrease in PM_(2.5)(from-5.08 to-6.32μg/(m3·year))and CO(from-0.053 to-0.090 mg/(m^(3)·year))because their decreasing rates were approximately the same in all the *** relatively stable O_(3)concentrations during the investigating period in BJ may be attributed to a faster decreasing rate of NO_(2)(BJ:-2.55μg/(m^(3)·year);TJ:-1.16μg/(m^(3)·year);HB:-1.34μg/(m3·year)),indicating that the continued reduction of NOx will be an effective mitigation strategy for reducing regional O_(3)*** positive correlations were found between daily maximum8 hr average(MDA8)O_(3)concentrations and vehicle population and highway freight transportation in ***,we speculate that the increase in rural NO_(x)emissions due to the increase in vehicle emissions in the vast rural areas around HB greatly accelerates regional O_(3)formation,accounting for the significant increasing trends of O_(3)in HB.

关键词： Tropospheric ozone The Beijing-Tianjin-Hebei region Spatio-temporal trends Rural vehicle emission

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Characterization of peroxyacetyl nitrate(PAN)under different PM_(2.5) concentration in wintertime at a North China rural site

引用

Journal of Environmental Sciences 2022年第4期34卷 221-232页

作者： Zhuoyu Li Guangzhao Xie Hui Chen Bixin Zhan Lin Wang yujing mu Abdelwahid Mellouki Jianmin Chen Department of Environmental Science&Engineering Fudan Tyndall CenterInstitute of Atmospheric SciencesFudan UniversityShanghai 200438China Center for Excellence in Regional Atmospheric Environment Institute of Urban EnvironmentChinese Academy of SciencesXiamen 361021China Research Center for Eco-Environmental Sciences Chinese Academy of SciencesBeijing 100085China Institut de Combustion AérothermiqueRéactivitéet EnvironnementCentre National de la Recherche Scientifique45071 Orléans cedex 02France

As a secondary pollutant of photochemical pollution,peroxyacetyl nitrate(PAN)has attracted a close attention.A four-month campaign was conducted at a rural site in North China Plain(NCP)including the measurement of PAN,O_(3),NO_(x),PM_(2.5),oxygenated volatile organic compounds(OVOCs),photolysis rate constants of NO_(2)and O_(3)and meteorological parameters to investigate the wintertime characterization of photochemistry from November 2018 to February *** results showed that the maximum and mean values of PAN were 4.38 and 0.93±0.67 ppbv during the campaign,*** PAN under different PM_(2.5)concentrations from below 75μg/m^(3)up to 250μg/m^(3),showed different diurnal variation and formation *** the PM_(2.5)concentration range of above 250μg/m^(3),PAN had the largest daily mean value of 0.64 ppbv and the fastest production rate of 0.33 ppbv/*** the perspective of PAN’s production mechanism,the light intensity and precursors concentrations under different PM_(2.5)pollution levels indicated that there were sufficient light intensity and high volatile organic compounds(VOCs)and NO_(x)precursors concentration even under severe pollution level to generate a large amount of ***,the bimodal staggering phenomenon of PAN and PM_(2.5)provided a basis that PAN might aggravate haze through secondary organic aerosols(SOA)formation.

关键词： Peroxyacetyl nitrate PM_(2.5) Wintertime North China Rural site

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

乳腺癌干细胞相关信号通路和生物标志物的研究进展

引用

现代肿瘤医学 2024年第5期32卷 941-947页

作者：穆玉晶孔健达汪唐顺史晓光北京中医药大学东直门医院北京100007 曲阜师范大学体育科学学院山东济宁273100

乳腺癌患者死亡率较高的主要原因为放化疗耐药导致癌症复发与转移,研究发现,乳腺癌复发转移与乳腺癌干细胞的存在相关,肿瘤内的乳腺癌干细胞具有自我更新和分化能力,且对传统放化疗具有一定抵抗性。而乳腺癌干细胞相关的信号通路和生物... 详细信息

乳腺癌患者死亡率较高的主要原因为放化疗耐药导致癌症复发与转移,研究发现,乳腺癌复发转移与乳腺癌干细胞的存在相关,肿瘤内的乳腺癌干细胞具有自我更新和分化能力,且对传统放化疗具有一定抵抗性。而乳腺癌干细胞相关的信号通路和生物标志物可为乳腺癌靶向治疗提供有力依据。目前已知乳腺癌干细胞与Wnt/β-catenin、Notch、NRF2、PI3K/AKT/mTOR和Hedgehog/Sonic Hedgehog等信号通路相关并有CD24、CD44、CD49、钙黏蛋白3、CD133、EpCAM、Erbb2/HER-2、CXCR1等标志物,这些标志物及信号通路有望用作生物标记,作为乳腺癌诊疗、复发进展及转移倾向性等方面的标志,但在未来研究中仍存在一定挑战。因此,综述与乳腺癌干细胞相关信号通路和生物标志物并进行展望,以期为乳腺癌治疗药物研究提供理论支持。

关键词：乳腺癌乳腺癌干细胞信号通路细胞标志物靶向治疗综述

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：