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气质维度量化评估施护对毛细支气管炎患儿高流量吸氧治疗的影响

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中国医药导报 2020年第9期17卷 95-98页

作者：胡禕静肖艳赏舒林华邵晨陶珏章洁如上海交通大学附属儿童医院呼吸科上海200062 上海交通大学附属儿童医院特诊部上海200062

目的探讨基于气质维度量化评估施护对毛细支气管炎患儿高流量吸氧的治疗效果。方法选取2018年1月~2019年2月上海交通大学附属儿童医院诊治的98例毛细支气管炎患儿作为研究对象,按照随机数字表法将其分为对照组和研究组,每组49例。两组... 详细信息

目的探讨基于气质维度量化评估施护对毛细支气管炎患儿高流量吸氧的治疗效果。方法选取2018年1月~2019年2月上海交通大学附属儿童医院诊治的98例毛细支气管炎患儿作为研究对象,按照随机数字表法将其分为对照组和研究组,每组49例。两组均给予高流量吸氧治疗,对照组实施常规护理,研究组采用基于气质维度量化评估进行施护。观察两组患儿治疗过程中配合度、临床症状及体征改善时间和住院时间及比较两组患儿护理前后气质维度的变化。结果研究组雾化过程中配合度评价等级好于对照组(P0.05);护理后,研究组活动水平、适应性、注意广度与持久性、反应阈限和心境评分均高于护理前,注意分散度、趋避性、反应强度低于护理前;对照组注意广度与持久性、心境评分高于护理前,注意分散度、反应强度低于护理前,且研究组适应性、注意广度与持久性、反应阈限、心境评分高于对照组,注意分散度、趋避性、反应强度评分低于对照组(均P<0.05)。结论气质维度量化评估施护可明显提高患儿高通量吸氧过程中的适应性,降低患儿注意分散度、趋避性和反应强度,促进患儿治疗中的配合,提高临床治疗效果。

关键词：小儿毛细支气管炎婴幼儿气质维度量化评估护理高流量吸氧疗效

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水电金属结构技术监督分类管理研究

水力发电 2023年第7期49卷 62-66页

作者：李文波张军章宇聪黄蓉胡钰婧刘懿莫剑国网湖南省电力公司电力科学研究院湖南长沙410007 长沙理工大学湖南长沙410114 湖南省湘电试验研究院湖南长沙410007 国网湖南省电力有限公司湖南长沙410118

水电厂金属结构部件众多,各类金属结构附件服役条件差异巨大,有必要科学地建立起分类管理办法,对金属结构部件进行分类技术监督管理。通过对过流件、转动件、紧固件、一般焊接件在技术监督方面的共性进行总结归纳,提出了在设计、安装、... 详细信息

水电厂金属结构部件众多,各类金属结构附件服役条件差异巨大,有必要科学地建立起分类管理办法,对金属结构部件进行分类技术监督管理。通过对过流件、转动件、紧固件、一般焊接件在技术监督方面的共性进行总结归纳,提出了在设计、安装、运行方面的注意要点,可为日后对这类部件进行分类管理以及开展技术监督工作提供参考。

关键词：水电金属结构过流件转动件紧固件一般焊接件技术监督分类管理研究

CATase-immobilized hydrogel platform molded by photo-enzyme coupling polymerization for effectively preventing postoperative abdominal adhesion

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中国科学:化学英文版 2023年第9期66卷 2664-2675页

作者： Min hu Mingyue Shi Xia Wang yujing Tang Dingze Zhou Kai Pan Qigang Wang School of Chemical Science and Engineering Tongji UniversityShanghai 200092China Translational Research Institute of Brain and Brain-Like Intelligence Shanghai Fourth People’s HospitalSchool of MedicineTongji UniversityShanghai 200434China

Redox homeostasis,which is regulated by enzymes acting as regulatory valves,is crucial for maintaining the proper functioning of biomolecules and a stable microenvironment for physiological processes by modulating the homeostasis of reactive oxygen species(ROS).Antioxidant enzymes in biocatalysis are used in the prevention or treatment of oxidative stress-related disease by counteracting the harmful effects of ***,designing a system that can efficiently immobilize antioxidant enzymes with high catalytic activity and stability is still *** by photo-biocatalysis,a novel and effective catalase(CATase)-immobilized hydrogel platform has been developed by the proposed photo-enzymatic coupled radical polymerization strategy of the visible light coupling with the porphyrin-centered *** higher catalytic stability and activity can therefore be achieved due to the preferential polymerization of CATase-immobilized hydrogel platform with a favorable three-dimensional network of enhanced coupling efficacy between light and *** mechanisms of free radical-initiated polymerization as well as the antioxidant cycle in the photo-CATase coupling system have been ***,the CATase-immobilized hydrogel platform affords an unprecedented antioxidant ability to scavenge ROS and provide an effective cellular protection mechanism against external oxidative ***,the CATase-immobilized hydrogel platform can effectively prevent peritoneal adhesion by reducing the expression of inflammatory ***,the novel CATase-immobilized hydrogel platform is a potential candidate for physical barriers that effectively prevent postoperative adhesion formation,offering a new anti-adhesion strategy for clinical applications.

关键词： photo-enzyme coupling polymerization enzyme immobilization antioxidative anti-inflammatory prevention abdominal adhesion

Basic Characteristics,Spatial Disparity and Its Major Influencing Factors of Service Industry in China

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Chinese Geographical Science 2009年第4期19卷 314-324页

作者： SHEN Yuming QIU Ling REN Wangbing CAO Yi hu Dan SONG yujing College of Resource Environment and Tourism Capital Normal University Beo＇ing 100048 China Institute of Geographic Sciences and Natural Resources Research Chinese Academy of Sciences Beijing 100101 China Graduate University of Chinese Academy of Sciences Beo＇ing 100049 China Academy of Macroeconomic Research National Development and Reform Commission Beijing 100038 China

Based on the analysis of its basic characteristics, this article investigated the disparities of Chinese service industry among the three regions （the eastern China, the western China and the middle China） and inter-provincial disparities of that in the three regions by Theil coefficient and cluster analysis. Then, major factors influencing its spatial disparity were explored by correlation analysis and regression analysis. The conclusions could be drawn as follows. 1） The development of Chinese service industry experienced three phases since the 1980s： rapid growth period, slow growth period, and recovery period. From the proportion of value-added and employment, its development was obviously on the low level. From the composition of industrial structure, traditional service sectors were dominant, but modem service sectors were lagged. Moreover, its spatial disparity was distinct. 2） The level of Chinese service industry was divided into five basic regional ranks： well-developed, developed, relatively-developed, underdeveloped and undeveloped regions, As a whole, the overall structure of spatial disparity was steady in 1990-2005. But there was notable gradient disparity in the interior structure of service industry among different provinces. Furthermore, the overall disparity expanded rapidly in 1990-2005. The inter-provincial disparity of service industry in the three regions, especially in the eastern China, was bigger than the disparity among the three regions. And 3） the level of economic development, the level of urban development, the scale of market capacity, the level of transportation and telecommunication, and the abundance of human resources were major factors influencing the development of Chinese service industry.

关键词： service industry Theil coefficient Pearson correlation coefficient cluster analysis spatial disparity China

单侧咀嚼力降低对大鼠髁突软骨细胞凋亡的影响

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现代口腔医学杂志 2019年第4期33卷 200-203页

作者：程洁谷建琦张栋吴永生袁军胡玉敬河北省人民医院口腔科石家庄050051 河北省人民医院血液科石家庄050051 河北省人民医院核医学科石家庄050051

目的探讨单侧咀嚼力降低对大鼠颞下颌关节软骨中caspase-12和Bak表达的影响。方法选取96只3周龄雄性SD大鼠,随机分为实验组及对照组各4组,每组12只。实验组大鼠行左侧所有磨牙拔除术,对照组大鼠不做任何处理,分别于拔牙后1d,7d,14d,28d... 详细信息

目的探讨单侧咀嚼力降低对大鼠颞下颌关节软骨中caspase-12和Bak表达的影响。方法选取96只3周龄雄性SD大鼠,随机分为实验组及对照组各4组,每组12只。实验组大鼠行左侧所有磨牙拔除术,对照组大鼠不做任何处理,分别于拔牙后1d,7d,14d,28d处死。HE染色观察软骨的形态学变化,RT-PCR方法检测caspase-12和Bak在关节软骨中的表达。结果实验组大鼠髁突软骨细胞随时间延长,逐渐出现细胞分层模糊,纤维断裂,软骨细胞空泡性变等退行性变化。拔牙后,实验组大鼠髁突软骨细胞的caspase-12和Bak的含量均高于对照组,差异有统计学意义(P<0.05)。随时间变化,实验组左侧caspase-12和Bak的含量逐渐升高,实验组右侧逐渐降低。结论咀嚼力降低会影响髁突软骨中caspase-12和Bak的含量,引起内质网应激介导的凋亡反应,内质网途径是髁突软骨细胞凋亡的重要途径之一。

关键词：颞下颌关节软骨 Bak caspase-12 咀嚼力

心脏X综合征患者核素心肌灌注显像特点及性别差异

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临床荟萃 2015年第12期30卷 1347-1349页

作者：李如意王学超胡玉敬李鑫柠张丽娜河北省人民医院心内科河北石家庄050051 河北省人民医院核医学科河北石家庄050051

目的探讨心脏X综合征患者核素心肌灌注显像的特点及性别差异。方法 36例经冠状动脉造影或冠状动脉计算机断层血管造影术及临床确诊为心脏X综合征患者,行静息/负荷99m锝甲氧基异丁基异腈(99mTcMIBI)门控心肌灌注显像(G-MPI),对比负荷和... 详细信息

目的探讨心脏X综合征患者核素心肌灌注显像的特点及性别差异。方法 36例经冠状动脉造影或冠状动脉计算机断层血管造影术及临床确诊为心脏X综合征患者,行静息/负荷99m锝甲氧基异丁基异腈(99mTcMIBI)门控心肌灌注显像(G-MPI),对比负荷和静息状态下核素分布情况评价心肌缺血的特点,同时对不同性别心脏X综合征患者临床危险因素及核素心肌灌注显像特点进行分析。结果经静息/负荷99mTc-MIBI G-MPI确诊的36例X综合征患者中23例(63.9%)为可逆性缺损,9例(25.0%)为固定性缺损,4例(11.1%)为反向再分布。全部468个左心室心肌节段中,负荷状态下127个(30.0%)节段表现为核素分布减低,前壁、下壁心肌灌注异常节段的比率均高于侧壁,差异均有统计学意义(P<0.05),男女患者在缺血程度上无明显差异,但女性患者以前壁缺血为主,而男性患者以前壁和下壁缺血为主(P<0.05)。全部入选的36例患者心肌灌注显示异常冠状动脉共19支,左前降支心肌灌注异常的比率高于冠状动脉左回旋支及右冠状动脉(P<0.05)。全部入选的36例心脏X综合征患者,女性14例(38.9%),与男性患者相比,女性患者年龄更大,体质量指数较高,合并高血脂、糖尿病史较多(P均<0.05),血清胆固醇、低密度脂蛋白胆固醇及尿酸水平较高(P均<0.05),吸烟史较少(P<0.05),两组患者高血压病史差异无统计学意义。结论静息/负荷99mTc-MIBI G-MPI对诊断心脏X综合征及评价心肌缺血具有重要的临床价值。

关键词：微血管性心绞痛放射性核素显像诊断,鉴别

乳头状甲状腺微小癌不宜作为术后^(131)Ⅰ治疗的决策依据

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外科理论与实践 2023年第6期28卷 529-535页

作者：蔡晓雨张瑞国胡玉敬王任飞边艳珠河北省人民医院核医学科河北石家庄050000 天津医科大学总医院核医学科天津300154 上海市第十人民医院核医学科上海200072

目的:分析术后接受^(131)Ⅰ治疗的乳头状甲状腺微小癌(papillary thyroid microcarcinoma,PTMC)与乳头状甲状腺非微小癌(papillary thyroid non-microcarcinoma,non-PTMC)病人的临床病理特征,并比较治疗转归的差异,以期指导PTMC的^(131)Ⅰ治疗决策。方法:纳入2015年1月至2020年12月在天津医科大学总医院核医学科^(131)Ⅰ治疗的1118例PTC病人,采用卡方检验及秩和检验比较PTMC组与non-PTMC组病人临床病理特征、^(131)Ⅰ治疗情况及治疗反应的差异,Kaplan-Meier法绘制两组的治疗反应不佳(incomplete response,IR)率曲线。结果:PTMC组病人多灶性、累及双叶的比例均高于non-PTMC组,腺外侵犯、T4、N1b、刺激性甲状腺球蛋白(stimulated thyroglobulin,sTg)>10μg/L及高危复发风险的比例低于non-PTMC组(P0.05)。结论:PTMC具有一定的侵袭性。经综合评估和规范^(131)Ⅰ治疗后,PTMC和non-PTMC病人治疗转归大致相同。PTMC的界定对^(131)Ⅰ治疗决策的指导价值极其有限。

关键词：甲状腺肿瘤甲状腺乳头状癌放射疗法碘放射性同位素治疗转归

Plant diversity in herbal tea and its traditional knowledge in Qingtian County, Zhejiang Province, China

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Plant Diversity 2020年第6期42卷 464-472页

作者： yujing Liu Renchuan hu Songsong Shen Zheng Zhang Jing Zhang Xiaoling Song Sheng Qiang Nanjing Agriculture University College of Life SciencesNanjing 210000China Guangxi Institute of Traditional Medical and Pharmaceutical Sciences Nanning 530022China

Herbal teas composed of locally occurring plant species have long been used as the primary form of health care in Qingtian County,Zhejiang Province,***,large-scale emigration overseas and an aging population threaten the conservation of traditional knowledge of these herbal *** knowledge about the plants used for these herbal teas is not well documented in Qingtian,despite their widespread *** aim of this study was to assess the plant-cultural diversity of plants used as herbal teas,and to point out the prospective value of herbal teas used by Qingtian *** study was conducted using semi-structured interviews,as well as field and market ***-three local informants were *** recorded plant resources,plant parts used,local names,and medicinal *** ethnobotanical indices,including cognitive salience(CS),frequency of citation(FC),index of informant consensus(Fic)and use value(UV),were calculated to analyze the level of representativeness and relative importance of plants used in herbal *** hundred and twenty-nine species belonging to 75 families and 113 genera were reported to be used in herbal tea,with Compositae being the richest *** plants are most commonly used to make herbal teas(66.7%).In this study,informants reported that 92.2%of plant species used in herbal teas are *** most utilized herbal preparation form is dry/*** reported that herbal teas are used to treat 31 *** results show that the highest representativeness,based on CS and FC,was recorded for species Actinidia *** on UV,the top five most used species are Goodyera schlechtendaliana,Plantago asiatica,Prunella vulgaris,Lophatherum gracile and Leonurus *** highest Fic was cited for dental *** study helps document the status of current herbal teas in *** use value and traditional knowledge of herbal teas have provided basic data for further research focused on bi

关键词： Herbal tea Medicine food homology plants Plant-cultural diversity Qingtian

Multi-scale fractures formation and distribution in tight sandstones—a case study of Triassic Chang 8 Member in the southwestern Ordos Basin

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Frontiers of Earth Science 2022年第2期16卷 483-498页

作者： Gaojian XIAO Ling hu Yang LUO yujing MENG Ali Bassam Taher AL-SALAFI Haoran LIU Key Laboratory of Tectonics and Petroleum Resources China University of GeosciencesWuhan 430074China Wenhua College Wuhan 430074China Faculty of Petroleum and Natural Resources Sana’a UniversitySana’aYemen Louisiana State University Baton Rouge LA 7080USA

Fracture system is an important factor controlling tight oil accumulation in the Triassic Chang 8 Member,southwestern Ordos Basin,China.A systematic characterization of the multi-scale natural fractures is a basis for the efficient tight oil *** on outcrops,seismic reflections,well cores,well logs(image and conventional logging),casting thin sections,and scanning electron microscope observation,the multi-scale fractures occurrences and their influences on Chang 8 tight sandstone reservoirs are *** results show that three periods of strike-slip faults and four scales of natural fractures developed,namely mega-scale(length>7×10^(7) mm),macro-scale(3.5×10^(5)

关键词： natural fractures characteristics geological significance tight sandstone reservoir Upper Triassic Yanchang Formation