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Climate Services for Water Resource Management in China: The Case Study of Danjiangkou Reservoir

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Journal of Meteorological Research 2021年第1期35卷 87-100页

作者： yujie WANG Xiang LI Song LIU Zhenyu han Lianchun SONG Zongjian KE Keyao CHEN Key Laboratory of Meteorological Disaster Ministry of Education(KLME)/Joint International Research Laboratory of Climate and Environment Change(ILCEC)/Collaborative Innovation Center on Forecast and Evaluation of Meteorological Disasters(CIC-FEMD)Nanjing University of Information Science&TechnologyNanjing 210044 School of Atmospheric Sciences Nanjing University of Information Science&TechnologyNanjing 210044 National Climate Center China Meteorological AdministrationBeijing 100081 hanjiang Water Resources&Hydropower Group Co. Ltd.Wuhan 430000

The efficiencies and effectiveness of water resource management are inextricably linked to climate services. This study demonstrates a climate information service for Danjiangkou Reservoir, which is the largest artificial lake in Asia, facing mounting challenges for flood control, water storage, and water diversion. Unlike traditional water resource management on the basis of short-term weather forecast and runoff monitoring, subseasonal to seasonal(S2S)and annual climate predictions as well as long-term climate change projections were well used to support the decision makers in Danjiangkou Reservoir. The National Climate Center(NCC) has projected the changes of future climate and extreme events by dynamically downscaling the Coupled Model Intercomparison Project phase 5(CMIP5)projections to 25-km resolution for the long-term planning of water resource management in Danjiangkou ***-time climate predictions based on climate models and downscaling interpretation and application methods at different timescales were also provided to meet the specific needs of earlier predictions and spatial refinement for the short-term diversion of the reservoir. Our results show that such climate services facilitated the Diversion Center of Danjiangkou Reservoir(DCDR) to reasonably control the operational water level, increased the ecological water supply to the northern portion of China by 844 million m^(3), and reduced as much as 1.67 billion m^(3) of abandoned water in 2019. In the future, it is necessary to develop climate prediction methods to increase spatial and temporal resolutions and prediction skills, and enhance interactions between providers and users.

关键词： climate service water resource management climate prediction climate projection reservoir

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二组分氨纶混纺产品定量化学分析方法

天津纺织科技 2019年第6期57卷 39-42页

作者：韩玉洁葛传兵李智李水张美玉牛攀登天纺标检测认证股份有限公司天津300193 天津市产品质量监督检测技术研究院天津300384

介绍了氨纶与聚酯纤维、聚酰胺纤维、纤维素纤维、动物纤维、聚丙烯腈纤维、醋酯纤维或三醋酯纤维等混纺的二组分氨纶混纺产品的定量化学分析方法、注意事项及方法的选择。旨在使检测人员能够正确、快速选择最佳的定量分析方法,提高定... 详细信息

介绍了氨纶与聚酯纤维、聚酰胺纤维、纤维素纤维、动物纤维、聚丙烯腈纤维、醋酯纤维或三醋酯纤维等混纺的二组分氨纶混纺产品的定量化学分析方法、注意事项及方法的选择。旨在使检测人员能够正确、快速选择最佳的定量分析方法,提高定量分析的准确性和时效性。

关键词：氨纶二组分混纺产品聚酯纤维聚酰胺纤维纤维素纤维动物纤维

1例新生儿PURA综合征的临床与遗传学分析

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妇儿健康导刊 2023年第15期2卷 88-90,F0003,F0004页

作者：朱法荣李晓梅刘晨韩玉杰杨春陈萌萌山东大学附属儿童医院新生儿科山东济南252000 山东大学附属儿童医院检验科山东济南252000

新生儿PURA综合征是一种罕见的常染色体显性遗传病,临床表现缺乏特异性。本文收集1例患儿的临床及实验室检查资料,利用Illumina二代测序平台,使用xGen®Exome Research Panel杂交捕获人类全部基因的外显子区及相邻内含子区域,应用高通量... 详细信息

新生儿PURA综合征是一种罕见的常染色体显性遗传病,临床表现缺乏特异性。本文收集1例患儿的临床及实验室检查资料,利用Illumina二代测序平台,使用xGen®Exome Research Panel杂交捕获人类全部基因的外显子区及相邻内含子区域,应用高通量测序仪进行测序,最后进行Sanger验证。发现5号染色体PURA基因的1号外显子存在一个自发的整码杂合变异c.697_699del(p.F233del),根据美国医学遗传学与基因组学学会标准,为致病性整码突变。经检索多个数据库报道罕见,进一步丰富了本病的数据库,拓宽临床医师对于自发基因突变疾病的诊断思路。

关键词： PURA基因新突变整码突变致病性新生儿

全环绕栅极场效应晶体管的Ⅰ-Ⅴ模型紧凑建模

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集成电路与嵌入式系统 2024年第10期24卷 9-18页

作者：王诗淳冯俊杰张保钦韩玉杰徐传忠曾霞于飞华侨大学信息科学与工程学院厦门361021 广州应用科技学院人工智能与电气工程学院肇庆511370 广东工业大学集成电路学院广州510006

基于表面电势提出了一种无结型全环绕栅极场效应晶体管的Ⅰ-Ⅴ模型。以一维泊松方程为基础,结合相应的边界条件,采用四阶龙格库塔算法对两个解析模型中基于物理原理的非线性超越方程组依次求解,建立了表面电势、中点电势与栅极电压相关... 详细信息

基于表面电势提出了一种无结型全环绕栅极场效应晶体管的Ⅰ-Ⅴ模型。以一维泊松方程为基础,结合相应的边界条件,采用四阶龙格库塔算法对两个解析模型中基于物理原理的非线性超越方程组依次求解,建立了表面电势、中点电势与栅极电压相关的数值模型。随后,根据数值模型中以中间参数形式表示的表面电势结果,利用Pao-Sah积分推导出全环绕栅极场效应晶体管的漏极电流。所提出的Ⅰ-Ⅴ模型结果与数值和实验数据均显示出良好的一致性,验证了该建模方法用于全环绕栅极场效应晶体管的可行性。此外,该方法实现了解析模型与数值模型的结合,在精度和效率之间实现了很好的平衡。

关键词：无结型全环绕栅极场效应晶体管 Ⅰ-Ⅴ模型表面电势 Pao-Sah模型

YAP-shRNA载体构建及其对食管鳞癌细胞系生物学行为的影响

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河南医学研究 2023年第15期32卷 2749-2753页

作者：韩高扬李小丽王瑞娟韩玉杰张仁锋魏创业孔晓煌连欢欢王金龙郑州大学附属郑州中心医院胸外科河南郑州450007 郑州大学第一附属医院肿瘤科河南郑州450000

目的评价Yes相关蛋白(YAP)在食管鳞癌(ESCC)中的表达及其临床意义,并研究YAP-shRNA对食管癌细胞系生物学行为的影响。方法运用免疫组化检测YAP在食管鳞癌组织和正常组织中的表达情况。设计shRNA质粒并转染食管癌细胞系(EC9706和EC109),... 详细信息

目的评价Yes相关蛋白(YAP)在食管鳞癌(ESCC)中的表达及其临床意义,并研究YAP-shRNA对食管癌细胞系生物学行为的影响。方法运用免疫组化检测YAP在食管鳞癌组织和正常组织中的表达情况。设计shRNA质粒并转染食管癌细胞系(EC9706和EC109),运用qRT-PCR和蛋白质印迹检测细胞系中YAP的表达情况。Transwell小室和CCK8检测转染前后细胞系的侵袭和增殖能力。结果YAP在食管鳞癌组织中高表达,且食管鳞癌YAP阳性的患者生存期明显缩短。RT-PCR和蛋白质印迹显示细胞转染成功且可挑选出转染效率最优的质粒。Transwell小室和CCK8检测到转染后的细胞系的侵袭和增殖能力下降。结论食管癌组织中YAP高表达,且YAP阳性的患者生存期明显缩短,抑制YAP表达将减弱食管癌细胞系的侵袭和增殖能力。

关键词：食管癌 Yes相关蛋白 Hippo 转染生存期

One-step hydrothermal synthesis of few-layered metallic phase MoS2 for high-performance supercapacitors

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Progress in Natural Science:Materials International 2024年第2期34卷 429-436页

作者： Jing Xu Xulong Yuan yujie Zhao Shaoqi Rui Qingling Jia han Li Shun Lu Bing Li Yongxing Zhang Xuebin Zhu Anhui Province Key Laboratory of Pollutant Sensitive Materials and Environmental Remediation Anhui Province Key Laboratory of Intelligent Computing and Applications Anhui Province Industrial Generic Technology Research Center for Alumics Materials Huaibei Normal University Chongqing Institute of Green and Intelligent Technology Chinese Academy of Sciences Key Laboratory of Materials Physics Institute of Solid State Physics HFIPS Chinese Academy of Sciences

In recent years,molybdenum disulfide（MoS2） has gained significant attention in the scientific *** MoS2demonstrates unique properties and potential ***,the synthesis of few-layered and high-purity 1T-MoS2is still a *** this study,we successfully employed a hydrothermal method to synthesize few-layered and high-purity *** purity of the material is controlled by a combination of sodium borohydride and ***,the few-layered 1T-MoS2exhibits exceptional performance as a supercapacitor,including the high specific capacitance(250.3 F g-1at a current density of 1 A g-1) and excellent long-trem cycling stability（90.7 % after 5000 cycles）.Meanwhile,the asymmetric device assembled by 6-FL-1TMoS2and active carbon on carbon cloths exhibits excellent flexibility and high energy and power density(23.1μWh cm-2at 600 μW cm-2,55 μWh cm-2at 12000 μW cm-2).This work provides valuable insights into the synthesis of few-layered and high-purity 1T-MoS2,opening up new avenues for further research and applications.

关键词： High-purity Few-layered One-pot hydrothermal method Supercapacitor

Identification of FUT7 hypomethylation as the blood biomarker in the prediction of early-stage lung cancer

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Journal of Genetics and Genomics 2023年第8期50卷 573-581页

作者： Rong Qiao Feifei Di Jun Wang yujie Wei Tian Xu Liping Dai Wanjian Gu Baohui han Rongxi Yang Department of Pulmonary Medicine Shanghai Chest HospitalShanghai Jiaotong UniversityShanghai 200030China Nanjing TANTICA Biotechnology Co.Ltd NanjingJiangsu 210061China Department of Clinical Laboratory Jiangsu Province Hospital of Chinese MedicineNanjingJiangsu 210029China Henan Institute of Medical and Pharmaceutical Sciences Academy of Medical ScienceZhengzhou UniversityZhengzhouHenan 450001China Department of Epidemiology and Biostatistics School of Public HealthNanjing Medical UniversityNanjingJiangsu 211166China Department of Environmental Genomics Jiangsu Key Laboratory of Cancer BiomarkersPrevention and TreatmentCollaborative Innovation Center for Cancer Personalized MedicineNanjing Medical UniversityNanjingJiangsu 211166China Department of Genetic Toxicology The Key Laboratory of Modern Toxicology of Ministry of EducationCenter for Global HealthSchool of Public HealthNanjing Medical UniversityNanjingJiangsu 211166China

Early detection of lung cancer (LC) is vital for reducing LC-related mortality. However, noninvasive diagnostic tools remain a great challenge. We aim to identify blood-based biomarkers for the early detection of LC. Here, LC-associated hypomethylation in alpha-1,3-fucosyltransferase VII (FUT7) is identified via the Illumina 850K array in a discovery study and validated by mass spectrometry in two independent casecontrol studies with blood samples from 1720 LC patients (86.8% LC at stage I, blood is collected before surgery and treatment) and 3143 healthy controls. Compared to the controls, blood-based FUT7 hypomethylation is identified in LC patients at stage I, and even in LC patients with malignant nodules ≤1 cm and in patients with adenocarcinoma in situ. Gender plays a role in the LC-associated FUT7 hypomethylation in blood, which is more significant in males than in females. We also reveal that FUT7 hypomethylation in LC could be enhanced by the advanced stage of cancer, involvement of lymph nodes, and larger tumor size. Based on a large sample size and semi-quantitative methods, our study reveals a strong association between blood-based FUT7 hypomethylation and LC, suggesting that methylation signatures in blood may be a group of potential biomarkers for detection of early-stage LC.

关键词： Lung cancer Early detection DNA methylation FUT7 Mass spectrometry

Narrow-bandgap materials for optoelectronics applications

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Frontiers of physics 2022年第1期17卷 89-121页

作者： Xiao-Hui Li Yi-Xuan Guo yujie Ren Jia-Jun Peng Ji-Shu Liu Cong Wang han Zhang School of Physics&Information Technology Shaanxi Normal UniversityXi’an710119China Shenzhen Key Laboratory of Two-Dimensional Materials and Devices/Shenzhen Engineering Laboratory of Phosphorene and Optoelectronics Collaborative Innovation Center for Optoelectronic Science and TechnologyKey Laboratory of Optoelectronic Devices and Systems of Ministry of Education and GuangdongShenzhen518060China

Narrow-bandgap materials possess the intriguing optical-electric properties and unique structures,which can be widely applied in the field of photonics,energy optoelectronic sensing and biomedicine,***,the researches on nonlinear optical properties of narrow-bandgap materials have attracted extensive attention *** this paper,we review the progress of narrow-bandgap materials from many aspects,such as background,nonlinear optical properties,energy band structure,methods of preparation,and *** materials have obvious nonlinear optical characteristics and the interaction with the short pulse laser excitation shows the extremely strong nonlinear absorption characteristics,which leads to the optical limiting or saturable absorption related to Pauli blocking and excited state ***,some of these novel narrow-bandgap materials have been utilized for the generation of ultrashort pulse that covers the range from the visible to mid-infrared wavelength ***,the study on these materials paves a new way for the advancement of optoelctronics devices.

关键词： narrow-bandgap materials saturable absorber ultrafast lasers modulator photodetectors

DNA/RNA helicase DHX36 is required for late stages of spermatogenesis

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Journal of Molecular Cell Biology 2022年第11期14卷 50-61页

作者： Kejia Zhang Tianxin Zhang yujie Zhang Jinyu Yuan Xinzhe Tang Chaobao Zhang Qianqian Yin Yonglian Zhang Ming-han Tong School of Life Science Hangzhou Institute for Advanced StudyUniversity of Chinese Academy of SciencesChinese Academy of SciencesHangzhou 310024China State Key Laboratory of Molecular Biology Shanghai Key Laboratory of Molecular AndrologyShanghai Institute of Biochemistry and Cell BiologyCenter for Excellence in Molecular Cell ScienceUniversity of Chinese Academy of SciencesChinese Academy of SciencesShanghai 200031China

Spermatogenesis is a highly complex developmental process that typically consists of mitosis, meiosis, and spermiogenesis. DNA/RNA helicase DHX36, a unique guanine-quadruplex (G4) resolvase, plays crucial roles in a variety of biological processes. We previously showed that DHX36 is highly expressed in male germ cells with the highest level in zygotene spermatocytes. Here, we deleted Dhx36 in advanced germ cells with Stra8-GFPCre and found that a Dhx36 deficiency in the differentiated spermatogonia leads to meiotic defects and abnormal spermiogenesis. These defects in late stages of spermatogenesis arise from dysregulated transcription of G4-harboring genes, which are required for meiosis. Thus, this study reveals that Dhx36 plays crucial roles in late stages of spermatogenesis.

关键词： Dhx36 meiosis guanine-quadruplex(G4) Spo11 synapsis meiotic recombination crossover