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The R2R3-MYB transcription factor GaPC controls petal coloration in cotton

The Crop Journal 2023年第5期11卷 1319-1330页

作者： Caiping Cai Fan Zhou Weixi Li yujia yu Zhihan Guan Baohong Zhang Wangzhen Guo State Key Laboratory of Crop Genetics&Germplasm Enhancement and Utilization Nanjing Agricultural UniversityNanjing 210095JiangsuChina Engineering Research Center of Ministry of Education for Cotton Germplasm Enhancement and Application Nanjing Agricultural UniversityNanjing 210095JiangsuChina Department of Biology East Carolina UniversityGreenvilleNC 27858USA

Although a few cases of genetic epistasis in plants have been reported, the combined analysis of genetically phenotypic segregation and the related molecular mechanism remains rarely studied. Here, we have identified a gene(named GaPC) controlling petal coloration in Gossypium arboreum and following a heritable recessive epistatic genetic model. Petal coloration is controlled by a single dominant gene,GaPC. A loss-of-function mutation of GaPC leads to a recessive gene Gapc that masks the phenotype of other color genes and shows recessive epistatic interactions. Map-based cloning showed that GaPC encodes an R2R3-MYB transcription factor. A 4814-bp long terminal repeat retrotransposon insertion at the second exon led to GaPC loss of function and disabled petal coloration. GaPC controlled petal coloration by regulating the anthocyanin and flavone biosynthesis pathways. Expression of core genes in the phenylpropanoid and anthocyanin pathways was higher in colored than in white petals. Petal color was conferred by flavonoids and anthocyanins, with red and yellow petals rich in anthocyanin and flavonol glycosides, respectively. This study provides new insight on molecular mechanism of recessive epistasis,also has potential breeding value by engineering GaPC to develop colored petals or fibers for multifunctional utilization of cotton.

关键词： Cotton Petal color R2R3-MYB transcription factor LTR-RT insertion Flavonoid/anthocyanin biosynthesis Recessive epistasis

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多模式影像诊疗点状内层脉络膜病变1例

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中华眼视光学与视觉科学杂志 2023年第9期25卷 710-712页

作者：于雨佳刘勇山东中医药大学济南250000 山东中医药大学附属医院山东省中医院眼科济南250000

患者,女,25岁,因"右眼视物模糊2年,左眼视物模糊9个月"于2022年1月24日至山东中医药大学附属医院眼科就诊。2020年1月患者因发热诱发右眼视物模糊,就诊于当地医院,查体右眼黄斑区散在点状黄白色病灶,诊断为右眼脉络膜炎,予右眼球后注射... 详细信息

患者,女,25岁,因"右眼视物模糊2年,左眼视物模糊9个月"于2022年1月24日至山东中医药大学附属医院眼科就诊。2020年1月患者因发热诱发右眼视物模糊,就诊于当地医院,查体右眼黄斑区散在点状黄白色病灶,诊断为右眼脉络膜炎,予右眼球后注射曲安奈德后症状缓解;2021年4月接种人乳头瘤病毒疫苗10 d后右眼视物模糊加重、左眼出现视物模糊,于某专科医院查见结核菌素试验、抗弓形体抗体、巨细胞病毒抗体、单纯疱疹病毒抗体、类风湿因子、人类白细胞抗原B27、抗核抗体阴性,行双眼球内注射康柏西普,治疗期间双眼视力持续下降。2022年1月患者双眼视物模糊加重,为求进一步诊治,遂来我院就诊。

关键词：结核菌素试验抗核抗体阴性类风湿因子双眼视物模糊双眼视力康柏西普右眼球脉络膜病变

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“新常态”下的供给侧改革与生态文明建设

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学术前沿 2017年第20期 74-77页

作者：李玉佳余力中国地质大学(北京)马克思主义学院西安交通大学经济与金融学院

改革开放以来,我国国民经济保持高速增长,但供给与需求之间存在结构性矛盾,经济增长与环境恶化之间的矛盾日益激化。2012年开始,我国提出生态文明建设,通过主动降低增长速度,引导宏观经济进入"新常态"。同时,依靠供给侧结构性改革,在改... 详细信息

改革开放以来,我国国民经济保持高速增长,但供给与需求之间存在结构性矛盾,经济增长与环境恶化之间的矛盾日益激化。2012年开始,我国提出生态文明建设,通过主动降低增长速度,引导宏观经济进入"新常态"。同时,依靠供给侧结构性改革,在改善经济增长质量的基础上,实现国民经济发展和生态文明建设的和谐统一。这就要求我国在供给侧改革和生态文明建设中,正确处理资源使用低效率引致的"资源诅咒"问题,协调好市场与政府之间的关系,同时积极发展生态产业,解决生态效率的提升问题,实现新的产业结构推动新的产品结构,新的产品结构形成新的供给结构,新的供给结构决定新的需求结构的发展格局。

关键词：供给侧改革生态文明经济增长

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2000t/d新型干法水泥厂生料粉磨系统的选择

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水泥技术 1987年第6期 7-12页

作者：余裕嘉

作者系统地介绍了生料粉磨系统在新型干法窑设计中的作用,系统选型应注意的问题,列举了各类系统的具体方案与各相应系统的配套设备及优缺点,并对各类系统,例如立磨系统、辊压机系统和通常的中卸管磨系统作了介绍和详尽的分析比较。

关键词：生料粉磨系统水泥厂莱歇磨立磨系统辊压机粉磨过程新型干法水泥生料制备选粉机生料磨入磨粒度

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基于玄府理论分析虫类药物在甲状腺相关眼病中的应用

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中国中医眼科杂志 2024年第8期34卷 771-775页

作者：于雨佳刘勇山东中医药大学济南250013 山东中医药大学附属医院济南250011

甲状腺相关眼病(TAO)发病机制复杂,病程长,预后不良,属久病顽疾。近年来,玄府理论作为一种中医学基本理论被广泛应用于TAO的临床诊疗中。玄府郁闭是TAO的基本病机,初见气郁玄府,久则痰湿、瘀血阻塞玄府。虫类药均为血肉有情之品,根据其... 详细信息

甲状腺相关眼病(TAO)发病机制复杂,病程长,预后不良,属久病顽疾。近年来,玄府理论作为一种中医学基本理论被广泛应用于TAO的临床诊疗中。玄府郁闭是TAO的基本病机,初见气郁玄府,久则痰湿、瘀血阻塞玄府。虫类药均为血肉有情之品,根据其“飞升走窜,无微不至”的特性,从清肝泻火、行气开玄府和化瘀散结、搜剔开玄府2个方面治疗TAO,为中医临床治疗TAO提供新思路。

关键词：甲状腺相关眼病玄府理论虫类药中医中药临床应用

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成人下颌偏斜伴颞下颌关节紊乱病的正畸治疗

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口腔医学 2018年第5期38卷 453-456,461页

作者：张玺顾郁嘉王林于剑南赵春洋南京医科大学口腔疾病研究江苏省重点实验室南京医科大学附属口腔医院正畸科江苏南京210029

本文报道了1例成人轻度骨性Ⅲ类,下颌偏斜伴颞下颌关节紊乱病的正畸治疗病例。该病例通过去程序化治疗及固定矫治器的掩饰性治疗,纠正前牙反牙合,下颌偏斜有所改善,关节症状消失。

关键词：骨性Ⅲ类下颌偏斜颞下颌关节紊乱病去程序化正畸治疗

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Diagnosing quantum crosstalk in superconducting quantum chips by using out-of-time-order correlators

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Chinese Physics B 2024年第11期33卷 207-211页

作者： yujia Zhang yu Zhang Shaoxiong Li Wen Zheng Yang yu National Laboratory of Solid State Microstructures School of PhysicsNanjing UniversityNanjing 210093China Shishan Laboratory Suzhou Campus of Nanjing UniversitySuzhou 215163China Synergetic Innovation Center of Quantum Information and Quantum Physics University of Science and Technology of ChinaHefei 230026China Hefei National Laboratory Hefei 230088China

Performance of a scalable quantum processor critically relies on minimizing crosstalk and unwanted interactions within the system,as it is vital for parallel controlled operations on *** present a protocol not only to provide information about residual coupling but also to effectively discriminate it from the influence of classical *** approach utilizes out-of-time-order correlators(OTOCs)as a signal of quantum crosstalk,making it applicable to various coupling forms and scalable *** demonstrate the effectiveness of our protocol,we provide a theoretical analysis and simulate its implementation in coupled superconducting qubits.

关键词： superconducting qubit crosstalk out-of-time-order correlator(OTOC)

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Anomaly detection of hot components in gas turbine based on frequent pattern extraction

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Science China(Technological Sciences) 2018年第4期61卷 567-586页

作者： LIU JinFu ZHU LinHai MA yujia LIU Jiao ZHOU WeiXing yu DaRen School of Energy Science and Engineering Harbin Institute of TechnologyHarbin 150001China AVIC Electromechanical(Shenyang)Sanyo Refrigeration Equipment Co.Ltd. Shenyang 110027China

Hot components operate in a high-temperature and high-pressure environment. The occurrence of a fault in hot components leads to high economic losses. In general, exhaust gas temperature(EGT) is used to monitor the performance of hot ***, during the early stages of a failure, the fault information is weak, and is simultaneously affected by various types of interference, such as the complex working conditions, ambient conditions, gradual performance degradation of the compressors and turbines, and noise. Additionally, inadequate effective information of the gas turbine also restricts the establishment of the detection model. To solve the above problems, this paper proposes an anomaly detection method based on frequent pattern extraction. A frequent pattern model(FPM) is applied to indicate the inherent regularity of change in EGT occurring from different types of interference. In this study, based on a genetic algorithm and support vector machine regression, the relationship model between the EGT and interference was tentatively built. The modeling accuracy was then further improved through the selection of the kernel function and training data. Experiments indicate that the optimal kernel function is linear and that the optimal training data should be balanced in addition to covering the appropriate range of operating conditions and ambient temperature. Furthermore, the thresholds based on the Pauta criterion that is automatically obtained during the modeling process, are used to determine whether hot components are operating abnormally. Moreover, the FPM is compared with the similarity theory, which demonstrates that the FPM can better suppress the effect of the component performance degradation and fuel heat value fluctuation. Finally, the effectiveness of the proposed method is validated on seven months of actual data obtained from a Titan130 gas turbine on an offshore oil platform. The results indicate that the proposed method can sensitively dete

关键词： frequent pattern model(FPM) support vector machine regression(SVR) genetic algorithm(GA) gas turbine hot components anomaly detection

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Effect of LiCoO_(2)on the positive temperature coefficient effect(PTC)properties of semiconductive composites and its ability to inhibit space charge injection

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High Voltage 2022年第5期7卷 1016-1022页

作者： Ciyao Wang Shumei Chen yu Long yujia Liu Chuncheng Hao Qingquan Lei Institute of Advanced Electrical Materials Qingdao University of Science and TechnologyQingdaoChina

The semiconductive shield layer is between the conductive core and the insulation layer of high voltage direct current transmission cables and plays an important role in suppressing the accumulation of space charge in the insulation *** the prevalent positive temperature coefficient effect(PTC)of the semiconducting layer leads to cable ageing and failure,this paper proposes the use of lithium cobaltate to modify the semiconducting shield to suppress its PTC effect and improve its ability to inhibit space charge *** ionic conductor LiCoO_(2)was prepared by the sol–gel ***_(2)particles with particle sizes ranging from tens to hundreds of nanometres were obtained by ball *** prepared LiCoO_(2)was used as a filler to modify the carbon black(CB)/ethylene vinyl acetate copolymer(EVA)/low density polyethylene(LDPE)*** melt blending and moulding cross-linking,LiCoO_(2)/CB/EVA/LDPE semiconductive shielding specimens were successfully ***,Thermally Stimulated Depolarisation Currents(TSDC),and pulsed electroacoustic measurements were conducted for the prepared *** PTC effect,which is common in polymer composites,was successfully suppressed,and the PTC strength was reduced by 17%.The resistivity of the semiconductive shielding layer was significantly *** ability of the semiconducting shield to inhibit space charge injection from the conductive core to the insulation layer was significantly *** LiCoO_(2)content is 0.5 wt%,the semiconductive shielding layer has the best performance,and the space charge in the insulation layer was reduced by 70%compared to the undoped semiconducting shield.

关键词： composites conductive effect

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Study on Refining Performances in Chemi-mechanical Pulping of Mixed Poplar and Eucalypt Woodchips

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Paper And Biomaterials 2019年第4期4卷 51-56页

作者： yu Shi Qun Li yujia Zhang Sinolight(Jinjiang)Hygiene Products Research Co. LtdJinjiangFujian Province362200China Tianjin Key Lab of Pulp and Paper Tianjin University of Science and TechnologyTianjin300457China KTH Royal Institute of Technology StockholmSE-10044Sweden

The refining performances of mixed poplar and eucalyptwoodchips(mixture ratio 6:4)were investigated at medium and highpulp consistency via chemi-mechanical pulping(CMP).The specificrefining energy consumption(SEC),fiber fraction proportion,andCanadian standard freeness(CSF)were determined to evaluate the effectsof pulp consistency and NaOH dosage on the refining performancesof mixed poplar and eucalypt *** the dosage of NaOHfor impregnation was maintained constant,the SEC and shive contentincreased with increasing pulp *** fractions obtainedfrom the Bauer-McNett classifier showed that higher pulp consistencycould be expected to yield more long fibers and shive in the *** increasing the NaOH dosage,the shive content and SEC *** the NaOH dosage was increased to 6%,the resultsindicated that it was difficult to reduce the shive content to less than 1%athigh pulp consistencies(25%~35%),whereas 0.18%shive fraction couldbe achieved at a medium pulp consistency(15%).

关键词： mixed woodchips chemi-mechanical pulping specific refiningenergy consumption pulp consistency fiber characteristics

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