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Synergistic coupling among Mg_(2)B_(2)O_(5),polycarbonate and N,Ndimethylformamide enhances the electrochemical performance of PVDF-HFP-based solid electrolyte

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Journal of Energy Chemistry 2024年第7期94卷 158-168页

作者： Yutong Jing Qiang Lv yujia Chen Bo wang Bochen Wu Cheng Li Shengbo Yang Zhipeng He Dianlong wang Huakun Liu Shixue Dou MIIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage State Key Laboratory of Urban Water Resource and EnvironmentSchool of Chemistry and Chemical EngineeringHarbin Institute of TechnologyHarbin 150001HeilongjiangChina Institute of Energy Material Science University of Shanghai for Science and TechnologyShanghai 200093China Institute for Superconducting&Electronic Materials Australian Institute of Innovative MaterialsUniversity of WollongongWollongongNSW 2500Australia

Polymer solid electrolytes(SPEs)based on the[solvate-Li+]complex structure have promising prospects in lithium metal batteries(LMBs)due to their unique ion transport ***,the solvation structure may compromise the mechanical performance and safety,hindering practical application of *** this work,a composite solid electrolyte(CSE)is designed through the organic-inorganic syner-gistic interaction among N,N-dimethylformamide(DMF),polycarbonate(PC),and Mg_(2)B_(2)O_(5) in poly(vinylidene fluoride-co-hexafluoropropylene)(PVDF-HFP).Flame-retardant Mg_(2)B_(2)O_(5) nanowires provide non-flammability to the prepared CSEs,and the addition of PC improves the dispersion of Mg_(2)B_(2)O_(5) ***,the organic-inorganic synergistic action of PC plasticizer and Mg_(2)B_(2)O_(5) nanowires pro-motes the dissociation degree of LiTFSI and reduces the crystallinity of PVDF-HFP,enabling rapid Li ion ***,Raman spectroscopy and DFT calculations confirm the coordination between Mg atoms in Mg_(2)B_(2)O_(5) and N atoms in DMF,which exhibits Lewis base-like behavior attacking adjacent C-F and C-H bonds in PVDF-HFP while inducing dehydrofluorination of *** on the syner-gistic coupling of Mg_(2)B_(2)O_(5),PC,and DMF in the PVDF-HFP matrix,the prepared CSE exhibits superior ion conductivity(9.78×10^(-4) s cm^(-1)).The assembled Li symmetric cells cycle stably for 3900 h at a current density of 0.1 mA cm^(-2) without short *** LFP||Li cells assembled with PDL-Mg_(2)B_(2)O_(5)/PC CSEs show excellent rate capability and cycling performance,with a capacity retention of 83.3%after 1000 cycles at 0.5 *** work provides a novel approach for the practical application of organic-inorganic Synergistic CSEs in LMBs.

关键词： Composite solid electrolytes Safe Li metal batteries Synergistic coupling effect Poly(vinylidene fluoride-co-hexafluoropro pylene)

Single-cell analysis defines the lineage plasticity of stem cells in cervix epithelium

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Cell Regeneration 2021年第1期10卷 367-384页

作者： Zixian Zhao yujia wang Yingchuan Wu Dandan Li Ting Zhang Yu Ma Xiaoming Teng Wei Zuo East Hospital School of MedicineTongji UniversityShanghaiChina Super Organ R&D Center Regend TherapeuticsShanghaiChina Shanghai Jincai East Secondary School ShanghaiChina Shanghai First Maternity and Infant Hospital Tongji UniversityShanghaiChina Ningxia Medical University YinchuanChina The First Affiliated Hospital Guangzhou Medical UniversityGuangzhouChina

Information about the dynamic change and post-injury regeneration of cervical epithelium is relatively rare,even though it is tightly related to gynecologic ***,using a feeder cell-based culturing system,we stably cloned mouse and human P63 and KRT5 expressing cells from the adult cervix as putative cervical stem/progenitor cells(CVSCs).When subjected to differentiation,the cultured cells gave rise to mature cervical epithelium by differentiating into squamous or glandular *** ability of endogenous mouse CVSCs to reconstitute cervical epithelium after injury was also evident from the genetic lineage tracing ***-cell transcriptomic analysis further classified the CVSCs into three subtypes and delineated their bi-lineage differentiation roadmap by pseudo-time *** also tracked the real-time differentiation routes of two representing single CVSC lines in vitro and found that they recapitulated the predicted roadmap in pseudo-time *** pathways including Wnt,TGF-beta,Notch and EGFR were found to regulate the cervical epithelial hierarchy and implicated the different roles of distinct types of cells in tissue homeostasis and ***,the above data provide a cloning system to achieve stable in vitro culture of a bi-lineage stem/progenitor cell population in the cervix,which has profound implications for our understanding of the cervix stem/progenitor cell function in homeostasis,regeneration,and disease and could be helpful for developing stem cell-based therapies in future.

关键词： Cervix Stem cells Regeneration Single-cell RNA-seq

Theoretical analysis of frequency modulation-to-amplitude modulation on the final optics and target of the SG Ⅱ-Up laser facility

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High Power Laser Science and Engineering 2024年第1期12卷 84-98页

作者： yujia Zhang Wei Fan Jiangfeng wang Xiaochao wang Xinghua Lu Dajie Huang Shouying Xu Yanli Zhang Mingying Sun Zhaoyang Jiao Shenlei Zhou Xiuqing Jiang Key Laboratory of High Power Laser and Physics Shanghai Institute of Optics and Fine MechanicsChinese Academy of SciencesShanghaiChina Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijingChina

Frequency modulation(FM)-to-amplitude modulation(AM) conversion is an important factor that affects the time±power curve of inertial confinement fusion(ICF) high-power laser facilities. This conversion can impact uniform compression and increase the risk of damage to optics. However, the dispersive grating used in the smoothing by spectral dispersion technology will introduce a temporal delay and can spatially smooth the target. The combined effect of the dispersive grating and the focusing lens is equivalent to a Gaussian low-pass filter, which is equivalent to 8 GHz bandwidth and can reduce the intensity modulation on the target to below 5% with 0.3 nm @ 3 GHz + 20 GHz spectrum phase modulation. The results play an important role in the testing and evaluating of the FM-to-AM on the final optics and the target, which is beneficial for comprehensively evaluating the load capacity of the facility and isentropic compression experiment for ICF.

关键词： dispersion grating frequency modulation-to-amplitude modulation conversion high-power laser facility inertial confinement fusion phase modulation

Single-cell RNA-Seq analysis identified kidney progenitor cells from human urine

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Protein & Cell 2021年第4期12卷 305-312页

作者： yujia wang Yu Zhao Zixian Zhao Dandan Li Hao Nie Yufen Sun Xiaobei Feng Ting Zhang Yu Ma Jing Nie Guangyan Cai Xiangmei Chen Wei Zuo East Hospital School of MedicineTongji UniversityShanghai 200092China Regend Therapeutics Co.Ltd. Zhangjiang Hi-tech ParkShanghai 201203China Ningxia Medical University Yinchuan 750004China The First Affiliated Hospital Guangzhou Medical UniversityGuangzhou 510120China Ruijin Hospital School of MedicineShanghai Jiaotong UniversityShanghai 200025China State Key Laboratory of Organ Failure Research National Clinical Research Center of Kidney DiseaseKey Laboratory of Organ Failure ResearchDivision of NephrologyNanfang HospitalSouthern Medical UniversityGuangzhou 510515China National Clinical Research Center for Kidney Diseases State Key Laboratory of Kidney DiseasesChinese PLA General HospitalBeijing 100039China

Dear Editor,Urine passes through the entire kidney and urinary tract system starting from the glomerulus and ending to the *** in the kidney and urinary tract could be exfoliated from the epithelium into the urine,while leukocyte could infiltrate from the local tissue into the urine,which makes the urine a useful subject for clinical evaluation of relevant diseases.

关键词： urine kidney urinary

基于光电容积脉搏波描记法可穿戴血管僵硬度检测技术的临床应用研究

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中国循证心血管医学杂志 2024年第3期16卷 272-274,282页

作者：王雨嘉芦婷婷李颖苇申玉玉沈晓影周听雨王慧泉曹丰李俊峡解放军总医院第二医学中心国家老年疾病临床医学研究中心北京100853 天津工业大学生命科学学院天津300071 解放军总医院第七医学中心心血管内科北京100700

目的建立基于光电容积法的便捷血管僵硬度检测技术,并评估临床诊断效能。方法采用光电容积脉搏波描记法,结合便携式掌式12导联心电信号采集终端,建立动脉脉搏波传导速度的简便检测技术,应用于55例中国人民解放军总医院心血管内科住院患... 详细信息

目的建立基于光电容积法的便捷血管僵硬度检测技术,并评估临床诊断效能。方法采用光电容积脉搏波描记法,结合便携式掌式12导联心电信号采集终端,建立动脉脉搏波传导速度的简便检测技术,应用于55例中国人民解放军总医院心血管内科住院患者,与现有动脉硬化检测技术比较,计算灵敏度、特异度、阳性预测值和阴性预测值等指标以及一致性检验。结果可穿戴动脉硬化检测装置对动脉硬化检测的灵敏度、特异度及准确性分别为85.7%、95.2%、91.4%,且具有较好的一致性(Kappa值>0.80)。结论可穿戴动脉硬化检测装置具有便携、操作简单、快速测量的优点,在居家和社区中具有较好的应用前景。

关键词：动脉硬化脉搏波传导速度可穿戴设备

Functional characterization of Bmcap in uric acid metabolism in the silkworm

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Insect Science 2024年第1期31卷 147-156页

作者： Linmeng Tang Dehong Yang Zhiwei Liu Yaohui wang Xu Yang yujia Liu Dongbin Chen Zheng Tang Yongping Huang Key Laboratory of Insect Developmental and Evolutionary Biology Center for Excellence in Molecular Plant SciencesShanghai Institute of Plant Physiology and EcologyChinese Academy of SciencesShanghaiChina CAS Center for Excellence in Biotic Interactions University of Chinese Academy of SciencesBeijingChina Central Research Institute Shanghai Pharmaceuticals Holding Co.Ltd.ShanghaiChina Departments of Neonatology International Peace Maternity and Child Health Hospital of China Welfare InstitutionSchool of MedicineShanghai Jiao Tong UniversityShanghaiChina

After a millennium of domestication,numerous silkworm mutants have emerged that exhibit transparent epidermis,which is caused by abnormally low levels of uric *** identified the Bombyx mori gene Bmcap(BMSK0003832)as the homolog of cappuccino,a subunit of the biogenesis of lysosome-related organelles complex-1(BLOC-1)that has been extensively characterized in human,mouse,and insect species,by analyzing the amino acid sequences of putative purine metabolism *** the clustered regularly interspaced palindromic repeats(CRISPR)/CRISPR-associated protein 9 system,we disrupted Bmcap,resulting in decreased uric acid levels in the silkworm epidermis and a translucent skin *** the Bmcap mutant,the purine metabolism,nitrogen metabolism,pyrimidine metabolism,and membrane system were altered compared to the wild *** of lysosome-related organelle complex genes play a role in the pigmentation and biogenesis of lysosome-related organelles(LROs)in platelets,melanocytes,and *** exhibit unique morphologies and functions in various tissues and *** of the Bmcap mutant will enhance our understanding of the uric acid metabolic pathway in silkworms,and this mutant offers a valuable silkworm model for LRO studies.

关键词： BLOC-1 subunit Bombyx mori cappuccino translucent mutation uric acid

Strengthening strategy for high-performance friction stir lap welded joints based on 5083 Al alloy

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International Journal of Minerals,Metallurgy and Materials 2024年第11期31卷 2498-2507页

作者： yujia Shen Jijie wang Beibei wang Peng Xue Fengchao Liu Dingrui Ni Bolv Xiao Zongyi Ma College of Material Science and Engineering Shenyang Aerospace UniversityShenyang 110136China Shi-changxu Innovation Center for Advanced Materials Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China CAS Key Laboratory of Nuclear Materials and Safety Assessment Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China Binzhou Institute of Technology Shandong Key Laboratory of Advanced Aluminium Materials and TechnologyWeiqiao-UCAS Science and Technology ParkBinzhou 256606China Centre of Excellence for Advanced Materials Dongguan 523808China

During aircraft,ship,and automobile manufacturing,lap structures are frequently produced among Al alloy skins,wall panels,and *** occurrence of welding defects severely decreases mechanical properties during friction stir lap welding(FSLW).This study focuses on investigating the effects of rotation rate,multipass welding,and cooling methods on lap defect formation,microstructural evolution,and mechanical *** defects were eliminated by decreasing welding speed,applying two-pass FLSW with a small welding tool,and introducing additional water cooling,thus leading to a remarkable increase in effective sheet thickness and lap *** above strategy yielded defect-free joints with an ultrafine-grained microstructure and increased tensile shear force from 298 to 551 N/*** fracture behavior of FSLW joints was systematically studied,and a fracture factor of lap joints was proposed to predict their fracture *** reducing the rotation rate,using two-pass welding,and employing additional water cooling strategies,an enlarged,strengthened,and defect-free lap zone with refined ultrafine grains was achieved with a quality comparable to that of lap welds based on 7xxx Al ***,this study provides a valuable FSLW method for eliminating hook defects and improving joint performance.

关键词： friction stir lap welding defect control microstructure fracture mechanisms mechanical properties

Editing of eIF(iso)4E.c confers resistance against Turnip mosaic virus in Brassica rapa

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Horticultural Plant Journal 2024年第4期10卷 1020-1034页

作者： yujia Liu Xiaoyun Xin Peirong Li Weihong wang Yangjun Yu Xiuyun Zhao Deshuang Zhang Jiao wang Fenglan Zhang Shujiang Zhang Shuancang Yu Tongbing Su State Key Laboratory of Vegetable Biobreeding Beijing Vegetable Research CenterBeijing Academy of Agriculture and Forestry ScienceBeijing 100097China National Engineering Research Center for Vegetables Beijing Key Laboratory of Vegetable Germplasms ImprovementKey Laboratory of Biology and Genetics Improvement of Horticultural Crops(North China)Key Laboratory of Urban Agriculture(North)of Ministry of AgricultureBeijing Vegetable Research CenterBeijing Academy of Agriculture and Forestry ScienceBeijing 100097China Institute of Vegetables and Flowers Chinese Academy of Agricultural SciencesBeijing 100081China

Turnip mosaic virus(TuMV)constitutes one of the primary diseases affecting Brassica rapa,severely impacting its production and resulting in crop failures in various regions *** research has demonstrated the significance of plant translation initiation factors,specifically the eIF4E and eIF4G family genes,as essential recessive disease resistance *** our study,we conducted evolutionary and gene expression studies,leading us to identify e IF(iso)4E.c as a potential TuMV-resistant *** CRISPR/Cas9 technology,we obtained mutant *** plants with edited eIF(iso)4E.c *** confirmed eIF(iso)4E.c confers resistance against TuMV through phenotypic observations and virus content ***,we employed ribosome profiling assays on eif(iso)4e.c mutant seedlings to unravel the translation landscape in response to ***,we observed a moderate correlation between the fold changes in gene expression at the transcriptional and translational levels(R^(2)=0.729).Comparative analysis of ribosome profiling and RNA-seq data revealed that plant-pathogen interaction,and MAPK signaling pathway-plant pathways were involved in eIF(iso)4E.c-mediated TuMV *** analysis revealed that sequence features,coding sequence length,and normalized minimal free energy,influenced the translation efficiency of *** study highlights that the loss of e IF(iso)4E.c can result in a highly intricate translation mechanism,acting synergistically with transcription to confer resistance against TuMV.

关键词： Brassica rapa eIF(iso)4E.c TuMV Ribo-seq

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山东武城地热供暖项目建设与实践

石油科技论坛 2024年第1期43卷 132-139页

作者：吕博舜赵忠新黄红祥郝文龙郑子健王雨佳刘妮琴曹伟中国石油冀东油田公司新能源事业部

“双碳”目标下,2021年冀东油田在山东省德州市武城县建设了首个中国石油域外清洁能源地热供暖项目,建成集中供暖面积235×10^(4)m^(2),后期扩建至310×10^(4)m^(2)。文章从地面工程建设布局、抽水回灌试验及实施效果、地质资源评价体... 详细信息

“双碳”目标下,2021年冀东油田在山东省德州市武城县建设了首个中国石油域外清洁能源地热供暖项目,建成集中供暖面积235×10^(4)m^(2),后期扩建至310×10^(4)m^(2)。文章从地面工程建设布局、抽水回灌试验及实施效果、地质资源评价体系、“6类18项”地热能开发技术运用,以及管理经验等方面进行分析,认真分析武城县地热地质情况,通过地热资源评价,合理制定及实施采灌试验,依托中国石油勘探开发、地质评价及工程建设等地热能开发利用技术优势,进行地热开发工程建设,达到项目建设运行效果,实现政府民生供暖项目保障要求,满足各项地热开发利用规范标准。该项目每年供热量55.656×10^(4)GJ,折合标准煤5.417×10^(4)t/a,减排CO_(2)量3.7919×10^(4)t/a,为成功实施城区集中供暖清洁替代探索出一条可行路径。

关键词：武城新能源 “双碳”目标地热供暖清洁替代