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Wild Gibbon Optimization Algorithm

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Computers, Materials & Continua 2024年第7期80卷 1203-1233页

作者： Jia Guo JinWang Ke Yan Qiankun Zuo Ruiheng Li Zhou He Dong Wang yuji Sato Hubei Key Laboratory of Digital Finance Innovation Hubei University of EconomicsWuhan430205China School of Information Engineering Hubei University of EconomicsWuhan430205China China Construction Third Engineering Bureau Installation Engineering Co. Ltd.Wuhan430074China Hubei Internet Finance Information Engineering Technology Research Center Hubei University of EconomicsWuhan430205China College of Informatics Huazhong Agricultural UniversityWuhan430070China Faculty of Computer and Information Sciences Hosei UniversityTokyo184-8584Japan

Complex optimization problems hold broad significance across numerous fields and ***,as the dimensionality of such problems increases,issues like the curse of dimensionality and local optima trapping also *** address these challenges,this paper proposes a novel Wild Gibbon Optimization Algorithm(WGOA)based on an analysis of wild gibbon population *** two strategies:community search and community *** community search strategy facilitates information exchange between two gibbon families,generating multiple candidate solutions to enhance algorithm ***,the community competition strategy reselects leaders for the population after each iteration,thus enhancing algorithm *** assess the algorithm’s performance,CEC2017 and CEC2022 are chosen as test *** the CEC2017 test suite,WGOA secures first place in 10 *** the CEC2022 benchmark functions,WGOA obtained the first rank in 5 *** ultimate experimental findings demonstrate that theWildGibbonOptimization Algorithm outperforms others in tested *** underscores the strong robustness and stability of the gibbonalgorithm in tackling complex single-objective optimization problems.

关键词： Complex optimization wild gibbon optimization algorithm community search community competition

DPY19L3 promotes vasculogenicmimicry by its C-mannosyltransferase activity

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Oncology Research 2024年第4期32卷 607-614页

作者： HASSAN BAYDOUN yuji KATO HIROKI KAMO ANNA HÜSCH HAYATO MIZUTA RYOTA KAWAHARA SIRO SIMIZU Department of Applied Chemistry Faculty of Science and TechnologyKeio UniversityYokohama223-8522Japan Department of Pharmacy and Biochemistry Faculty of ScienceUniversity of TübingenTübingen72074Germany

C-mannosylation is a post-translational modification that occurs intracellularly in the endoplasmic *** humans,biosynthesis of C-mannosylation in proteins containing thrombospondin type 1 repeat is catalyzed by the DPY19 family;nonetheless,biological functions of protein C-mannosylation are not yet fully understood,especially in tumor *** mimicry(VM)is the formation of fluid-conducting channels by highly invasive and genetically deregulated tumor cells,enabling the tumors to form matrix-embedded vasculogenic structures,containing plasma and blood cells to meet the metabolic demands of rapidly growing *** this study,we focused on DPY19L3,a C-mannosyltransferase,and aimed to unravel its role in *** of DPY19L3 inhibited the formation of VM in HT1080 human fibrosarcoma ***-expression of wild-type DPY19L3 recovered VM formation;however,DPY19L3 isoform2,an enzymatic activity-defect mutant,did not restore it,suggesting that the C-mannosyltransferase activity of DPY19L3 is crucial to its ***,the knockdown of DPY19L3 in MDA-MB-231 breast cancer cells hindered its network formation ***,our findings suggest that DPY19L3 is required for VM formation and stipulate the relevance of C-mannosylation in oncogenesis.

关键词： C-mannosylation Vasculogenic mimicry DPY19L3

Natural history of asymptomatic gallbladder stones in clinic without beds:A long-term prognosis over 10 years

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World Journal of Clinical Cases 2024年第1期12卷 42-50页

作者： yuji Sakai Toshio Tsuyuguchi Hiroshi Ohyama Junichiro Kumagai Takashi Kaiho Masayuki Ohtsuka Naoya Kato Tadao Sakai Department of Gastroenterology Sakai ClinicKimistu 299-1162Japan Department of Gastroenterology Graduate School of MedicineChiba UniversityChiba 260-8677Japan Department of Gastroenterology Chiba Prefectural Sawara HospitalChiba Prefectural Sawara HospitalSawara 287-0003Japan Department of Gastroenterology Kimitsu Central HospitalKisarazu 292-8535Japan Department of Surgery Kimitsu Central HospitalKisarazu 292-8535Japan Department of General Surgery Graduate School of MedicineChiba UniversityChiba 260-8677Japan

BACKGROUND Several studies have explored the long-term prognosis of patients with asymp-tomatic gallbladder *** reports were primarily conducted in facilities equipped with beds for addressing symptomatic *** To report the long-term prognosis of patients with asymptomatic gallbladder stones in clinics without bed *** We investigated the prognoses of 237 patients diagnosed with asymptomatic gallbladder stones in clinics without beds between March 2010 and October *** symptoms developed,patients were transferred to hospitals where appropriate treatment was *** investigated the asymptomatic and survival periods during the *** Among the 237 patients,214(90.3%)remained asymptomatic,with a mean asymptomatic period of 3898.9279±46.871 d(50-4111 d,10.7 years on average).Biliary complications developed in 23 patients(9.7%),with a mean survival period of 4010.0285±31.2788 d(53-4112 d,10.9 years on average).No patient died of biliary *** The long-term prognosis of asymptomatic gallbladder stones in clinics without beds was *** the condition became symptomatic,the patients were transferred to hospitals with beds that could address it;thus,no deaths related to biliary complications were *** finding suggests that follow-up care in clinics without beds is possible.

关键词： Gallbladder stone Acute cholangitis Acute cholecystitis Asymptomatic gallbladder stone Symptomatic gallbladder stone

Fundamental Study on Response Properties of Structures Constructed on Lunar Regolith

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Open Journal of Earthquake Research 2024年第1期13卷 27-40页

作者： yuji Miyamoto Takaharu Nakano Toshio Kobayashi Department of Architecture and Civil Engineering Fukui University of Technology Fukui Japan Graduate School of Engineering Osaka University Osaka Japan SANSEI Inc. Tokyo Japan

The Artemis Program, for constructing the lunar base, is in progress. How to design and construct architectural and civil engineering structures in the lunar environment has become an important issue. The lunar surface is covered with soft sand, called regolith, and it is required to protect lunar bases and structures, as well as internal precision equipment, against vibrational disturbances such as moonquakes and meteorite collisions. Therefore, in this study, the static and cyclic triaxial compression tests of the regolith simulant were conducted. The reference strain and equivalent damping factor of the regolith simulant were smaller compared to sandy soil on Earth. In addition, a shaking table test using model specimens was conducted on the response properties of regolith ground alone and structures set on regolith ground. The buried foundation and pile foundation notably suppressed the horizontal response attributed to the rocking component compared to a direct foundation.

关键词： Lunar Development Regolith Soil-Structure Interaction Triaxial Compression Test Shaking Table Test

Enzyme-linked immunosorbent assay of 3 Screen Islet Cell Autoantibody in patients with autoimmune thyroid disease

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World Journal of Diabetes 2024年第5期15卷 935-944页

作者： Eiji Kawasaki Hidekazu Tamai Takahiro Fukuyama Yoko Sagara Ryutaro Hidaka Aira Uchida Masayuki Tojikubo Narihito Tatsumoto Yuko Akehi yuji Hiromatsu The Diabetes Thyroid and Endocrine CenterShin-Koga HospitalKurume 830-8577Japan

BACKGROUND In recent years,the emergence of multiplex technology that can simultaneously measure multiple anti-islet autoantibodies has become particularly valuable for the staging and early diagnosis of immune-mediated type 1 diabetes(T1D).While it has been established that 20%-30%of T1D patients suffer from autoimmune thyroid disease(AITD),there is limited available data regarding the presence of anti-islet autoantibodies in AITD *** commercially available anti-islet autoantibodies,glutamic acid decarboxylase 65 autoantibodies(GADAs)are often the first marker measured in general clinical *** To investigate the frequency of anti-islet autoantibodies in AITD *** Our study involved four hundred ninety-five AITD patients,categorized into three distinct groups:AITD with T1D(n=18),AITD with phenotypic type 2 diabetes(T2D)(n=81),and AITD without diabetes(n=396),and the enzyme-linked immunosorbent assay(ELISA)was employed to determine the frequencies of 3 Screen Islet Cell Autoantibody(3 Screen ICA),GADA,insulinoma-associated antigen-2 autoantibodies(IA-2As),and zinc transporter 8 autoantibodies(ZnT8As)within these *** The frequency of 3 Screen ICA in AITD patients with T1D,T2D,and those without diabetes were 88.9%,6.2%,and 5.1%,respectively,with no significant difference seen between the latter two ***,the frequency of 3 Screen ICA was 11.1%higher in AITD patients with T1D,1.3%higher in AITD patients with T2D,and 1.1%higher in AITD patients without diabetes compared to GADA,***,12.5%,20.0%,and 20.0%of the 3 Screen ICA-positive patients were negative for ***,1.3%of the AITD patients who tested negative for 3 Screen ICA in both the AITD with T2D and non-diabetic AITD groups were found to be positive for individual *** the 3 Screen ICA-positive patients,there was a significantly higher proportion of individuals with multiple autoantibodies in AITD patients with T1D com

关键词： Anti-islet autoantibodies Autoimmune thyroid disease Real-world practice Retrospective study Type 1 diabetes

沁水盆地煤层气井排采水的地球化学特征及来源示踪

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天然气地球科学 2024年

作者：方鲁加陈碧莹能惠 yuji Sano 徐胜 Marine Core Research Institute Kochi University 天津大学地球系统科学学院

次生生物气与地下水之间存在一定的关系，特别是在煤层气等天然气储层中，了解地下水与次生生物成因甲烷之间的关系对于天然气勘探和开发具有重要意义。基于中国沁水盆地6个区块的57个煤层气井排采水和3个河水样品的化学组成、氢氧同位... 详细信息

次生生物气与地下水之间存在一定的关系，特别是在煤层气等天然气储层中，了解地下水与次生生物成因甲烷之间的关系对于天然气勘探和开发具有重要意义。基于中国沁水盆地6个区块的57个煤层气井排采水和3个河水样品的化学组成、氢氧同位素组成(δ18OH2O和δDH2O)和溶解无机碳(DIC)碳同位素组成(δ13CDIC和Δ14CDIC)，深入剖析了地下水与次生生物成因甲烷之间的复杂关系。研究结果表明：氢氧同位素分布在大气降水线附近，煤层气井排采水主要来源于大气降雨，硫酸盐微生物还原作用是郑庄和阳泉区块氘同位素富集的主要原因。研究区煤层气井排采水化学组成以Na-HCO3型为主，其变化受到水—岩相互作用、阳离子交换等过程的控制。沁水盆地6个研究区块煤层气井排采水的稳定碳同位素呈现高δ13CDIC值(-4.19‰～34.80‰，平均为16.51‰)、且与溶解无机碳含量呈明显正相关关系可能是微生物产甲烷作用的结果。煤层气井排采水中δ13CDIC与SO42-的负相关性以及δDH2O正漂移等指标也指向沁水盆地不同成熟度煤岩中次生生物成因甲烷的广泛存在。δ13CDIC与镜质体反射率(ROmax)的负相关性进一步表明沁水盆地不同成熟度煤层中广泛存在次生生物成因甲烷，且在浅埋藏和成熟度较低的煤层中最为显著。地球化学与微生物学的结合将会进一步阐明次生生物甲烷的形成途径和机制。

关键词：煤层气井排采水水化学特征碳同位素次生生物甲烷沁水盆地

Population-based X-ray gastric cancer screening in Hiroshima prefecture, Japan

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World Journal of Clinical Oncology 2024年第2期15卷 271-281页

作者： Nhu Thi Hanh Vu yuji Urabe Duc Trong Quach Shiro Oka Toru Hiyama Department of Internal Medicine University of Medicine and Pharmacy at Ho Chi Minh CityHo Chi Minh 700000Viet Nam Department of Endoscopy Hiroshima University HospitalHiroshima 734-8551Japan Department of Gastrointestinal Endoscopy and Medicine Hiroshima University HospitalHiroshima 734-8551Japan Department of Gastroenterology Hiroshima University HospitalHiroshima 734-8551Japan Health Service Center Hiroshima UniversityHigashihiroshima 739-8514Japan

BACKGROUND X-ray gastric cancer(GC)screening has been shown to decrease ***-based X-ray GC screening has been performed in Hiroshima Prefe-cture,Japan,since 1983 but time trends and the efficacy of the method over 39 years have not been *** This was a population-based retrospective *** data were derived from aggregated data of the Hiroshima Regional Health Medical Promotion Organization,including the number and rate of participants and those requiring esophagogastroduodenoscopies(EGDs),the number and rate of participants diagnosed as having GC,and the positive predictive value of the abnormal findings detected by X-ray and confirmed by *** number and rate of esophageal cancers were also ***,the cost of detecting one GC was *** The number of participants has decreased during the last four decades,from 39925 in 1983 to 12923 in *** rate of those requiring EGDs decreased significantly in recent years(P<0.001).The number of participants diagnosed as having GC has also declined,from 76 to 10 ***,the rate of cases diagnosed as GC among the participants remained around 0.1%.The positive predictive value increased significantly in recent years except during *** number and rate of accidentally detected esophageal cancers have risen recently,from 0%in 2008 to 0.02%in 2021,one-fifth of the diagnosis rate of *** GC diagnosis costs approximately 4200000 Japanese Yen(30000 United States Dollars)for the X-ray screenings and *** X-ray GC screening in Hiroshima has been efficient,but one challenge is the *** cancers may also need to be considered because they have gradually increased in recent years.

关键词： Population Retrospective studies X-ray Gastric cancer Screening

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计及区域建筑群生长特性的动态冷热负荷预测

浙江大学学报（工学版） 2024年第1期58卷 140-149页

作者：杜玉吉钟崴钱辉金俞自涛浙江大学工程师学院浙江杭州310058 中节能城市节能研究院有限公司江苏常州213000

考虑区域建筑群的动态生长特性,结合负荷计算理论、灰色Verhulst模型及等维新息灰色理论,采用MATLAB构建完整的区域动态冷热负荷预测方法,以常州高铁新城2017—2022年的建筑面积为历史数据,对区域未来10年的冷热负荷进行预测.结果表明,... 详细信息

考虑区域建筑群的动态生长特性,结合负荷计算理论、灰色Verhulst模型及等维新息灰色理论,采用MATLAB构建完整的区域动态冷热负荷预测方法,以常州高铁新城2017—2022年的建筑面积为历史数据,对区域未来10年的冷热负荷进行预测.结果表明,采用基于等维新息灰色理论的Verhulst灰色模型建立的3种业态面积预测方程拟合精度均达到一级.高铁新城未来10年冷热负荷先快速增长后缓慢增长直至饱和,达到饱和的时间约为2030年,冷、热负荷饱和规模分别为436、228 MW,与采用面积指标法的计算结果(冷负荷为472 MW、热负荷为285 MW)相比,分别降低了约7.52%、19.86%.

关键词：区域供冷供热系统动态负荷预测建筑群生长特性灰色模型新型城镇化

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营商环境“啄木鸟”:面向政企争议的诉源治理

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中国行政管理 2024年第6期40卷 70-81页

作者：耿玉基秦文俊合肥工业大学文法学院中共安徽省委政法委员会合肥230009

政企关系和谐度与营商环境的建设质效呈正相关关系。近年来地方党政机关积极开展的诉源治理犹如森林卫士“啄木鸟”,从源头上预防政企纠纷,经由非诉方式化解争议,检视营商环境短板,根治行政失当问题。目前,长三角诉源治理主要呈现为行... 详细信息

政企关系和谐度与营商环境的建设质效呈正相关关系。近年来地方党政机关积极开展的诉源治理犹如森林卫士“啄木鸟”,从源头上预防政企纠纷,经由非诉方式化解争议,检视营商环境短板,根治行政失当问题。目前,长三角诉源治理主要呈现为行政复议主渠道型、“府法检”联动治理型、区域协同共治型,具有经验禀赋、治理细化、示范辐射等特性,对营商环境建设具有积极作用。但是,基层个案实践的诉源治理存在后置化、单一化、形式化倾向,故有待及早规范执法裁量,约束涉营商决策行为,采用多元化的实质治理而定分止争;合理借鉴世界银行最新B-READY营商评估体系的新标准新方法,注重实效导向与数字赋能,释放诉源治理的制度张力,从而改进政府管理与涉企服务,持续提升经营主体的满意度与获得感。

关键词：诉源治理营商环境政府管理执法裁量

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