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FGM-SPCL:Open-Set Recognition Network for Medical Images Based on Fine-Grained Data Mixture and Spatial Position Constraint Loss

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Chinese Journal of electronics 2024年第4期33卷 1023-1033页

作者： Ruru ZHANG Haihong e Lifei YUAN Yanhui wang Lifei wang Meina SONG School of Computer Science Beijing University of Posts and Telecommunications engineering Research Center of Information Networks Ministry of Education Hebei eye Hospital

The current intelligent auxiliary diagnosis models all follow the closed-set recognition setting. After the model is deployed online, the input data is often not completely controlled. Diagnosing an untrained disease as a known category would lead to serious medical malpractice. Therefore, realizing the open-set recognition is significant to the safe operation of the intelligent auxiliary diagnosis model. Currently, most open-set recognition models are studied for natural images, and it is very challenging to obtain clear and concise decision boundaries between known and unknown classes when applied to fine-grained medical images. We propose an open-set recognition network for medical images based on fine-grained data mixture and spatial position constraint loss(FGM-SPCL) in this *** the fine graininess of medical images and the diversity of unknown samples, we propose a fine-grained data mixture(FGM) method to simulate unknown data by performing a mixing operation on known data to expand the coverage of unknown data difficulty levels. In order to obtain a concise and clear decision boundary, we propose a spatial position constraint loss(SPCL) to control the position distribution of prototypes and samples in the feature space and maximize the distance between known classes and unknown classes. We validate on a private ophthalmic OCT dataset, and extensive experiments and analyses demonstrate that FGM-SPCL outperforms state-of-the-art models.

关键词： Analytical models Fine-grained image recognition Prototypes Aerospace electronics Spatial databases Robustness Data models

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Jigsaw-Sketch: a fast and accurate algorithm for finding top-k elephant flows in high-speed networks

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Science China(Information Sciences) 2024年第4期67卷 113-130页

作者： Boyu ZHANG He HUANG Yu-e SUN Yang DU Dan wang School of Computer Science and Technology Soochow University School of Rail Transportation Soochow University

Finding top-k elephant flows in high-speed networks is one of the most fundamental network measurement tasks. It is more challenging than per-flow size estimation since the IDs and sizes of top-k flows must be tracked simultaneously. Most existing studies only record the IDs of a small number of elephant flows to fit their estimators in the extremely limited high-speed on-chip memory. However, these solutions need too many memory accesses when a packet arrives to track the elephant flows with high accuracy, which limits their practicability. Therefore, this paper proposes Jigsaw-Sketch, a new algorithm to find the top-k elephant flows with much fewer memory accesses while achieving high memory efficiency and accuracy. In this design, we propose a novel two-stage jigsaw storage scheme, which can capture the candidate top-k flows from massive network steams efficiently, and further find the top-k elephant flows with high memory efficiency and only a few memory accesses for each packet. extensive experimental results based on real network traces show that Jigsaw-Sketch improves the packet processing throughput by at least 86%, while achieving smaller memory footprints and higher accuracy compared to the SOTA.

关键词： sketch top-$k$ network measurement elephant flow high-speed networks

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A low-noise,high-gain,and large-dynamic-range photodetector based on a JFeT and a charge amplifier

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Frontiers of Information Technology & electronic engineering 2024年第2期25卷 316-322页

作者： Jinrong wang Shuang'e WU Chengdong MI Yaner QIU Xin'ai BAI Department of Physics Lyuliang UniversityLvliang033001China Guangdong Provincial Key Laboratory of Fiber Laser Materials and Applied Techniques South China University of TechnologyGuangzhou510640China

We demonstrate a low-noise,high-gain,and large-dynamic-range photodetector(PD)based on a junction field-effect transistor(JFeT)and a charge amplifier for the measurement of quantum noise in Bell-state detection(BSD).Particular photodiode junction capacitance allows the silicon N-channel JFeT 2sk152 to be matched to the noise requirement for charge amplifier *** electronic noise of the PD is effectively suppressed and the signal-to-noise ratio(SNR)is up to 15 dB at the analysis frequency of 2.75 MHz for a coherent laser power of 50.08µ*** combining of the inductor and capacitance,the alternating current(AC)and direct current(DC)branches of the PD can operate linearly in a dynamic range from 25.06µW to 17.50 *** PD can completely meet the requirements of SNR and dynamic range for BSD in quantum optics experiments.

关键词： Quantum noise Bell-state detection(BSD) Photodetector(PD) Junction field-effect transistor(JFeT) Charge amplifier

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OsbZIP53 Negatively Regulates Immunity Response by Involving in Reactive Oxygen Species and Salicylic Acid Metabolism in Rice

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Rice science 2024年第2期31卷 190-202,I0022-I0028页

作者： WU Lijuan HAN Cong wang Huimei He Yuchang LIN Hai wang Lei CHeN Chen e Zhiguo State Key Laboratory of Rice Biology and Breeding China National Rice Research InstituteHangzhou 310006China Jiangsu Key Laboratory of Crop Genetics and Physiology/Key Laboratory of Plant Functional Genomics of the Ministry of education/Jiangsu Key Laboratory of Crop Genomics and Molecular Breeding/Jiangsu Co-Innovation Center for Modern Production Technology of Grain Crops Agricultural College of Yangzhou UniversityYangzhou 225009China

The basic region/leucine zipper(bZIP)transcription factors play important roles in plant development and responses to abiotic and biotic ***53 regulates resistance to Magnaporthe oryzae in rice by analyzing APIP5-RNAi transgenic *** further investigate the biological functions of OsbZIP53,we generated osbzip53 mutants using CRISPR/Cas9 editing and also constructed OsbZIP53 over-expression transgenic *** analysis of phenotypical,physiological,and transcriptional data showed that knocking-out OsbZIP53 not only improved disease resistance by inducing a hypersensitivity response in plants,but also regulated the immune response through the salicylic acid ***,disrupting OsbZIP53 increased H2O2 accumulation by promoting reactive oxygen species generation through up-regulation of several respiratory burst oxidase homologs(Osrboh genes)and weakened H2O2 degradation by directly targeting *** addition,the growth of osbzip53 mutants was seriously impaired,while OsbZIP53 over-expression lines displayed a similar phenotype to the wild type,suggesting that OsbZIP53 has a balancing effect on rice immune response and growth.

关键词： OsbZIP53 hypersensitive response reactive oxygen species metabolism rice immunity salicylic acid transcription factor

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New record of the feather star Palaeocomatella hiwia(echinodermata:Crinoidea:Comatulida)from Zhenbei Seamount in South China Sea:new insights into the taxonomic position of Palaeocomatella

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Journal of Oceanology and Limnology 2024年第1期42卷 244-251页

作者： Shao’e SUN Zijie MeI Zhongli SHA Jing wang Nansheng CHeN Department of Marine Organism Taxonomy and Phylogeny Institute of OceanologyChinese Academy of SciencesQingdao 266071China CAS Key Laboratory of Marine ecology and environmental Sciences Institute of OceanologyChinese Academy of SciencesQingdao 266071China Laoshan Laboratory Qingdao 266237China Shandong Province Key Laboratory of experimental Marine Biology Institute of OceanologyChinese Academy of SciencesQingdao 266071China Center for Ocean Mega-Science Chinese Academy of SciencesQingdao 266071China University of Chinese Academy of Sciences Beijing 100049China

One specimen belonging to the family Comatellinae was collected from the Zhenbei Seamount(332.5–478.2 m)in the South China Sea in July *** on the morphological characters,the specimen was identified as Palaeocomatella hiwia McKnight,*** is first recorded from China Sea and redescribed in *** specimen differs from the original description from New Zealand for never showing syzygy at br4+5 or br5+6 on interior and br1+2 on exterior ***,it is much conform to the redescription to specimens from Indonesia,with only differences in position of the second syzygy and distalmost pinnule *** is deposited in the Institute of Oceanology,Chinese Academy of *** analyses based on the mitochondrial c oxidase subunit I(COI)and 16S rRNA genes indicated that *** was nested within the tribe Phanogeniini and clustered with Aphanocomaster ***,*** showed same morphological features in terms of mouth placement,comb location,and number of comb teeth rows as other genera of ***,we suggest that the genus Palaeocomatella should be put in the tribe Phanogeniini.

关键词： new record Palaeocomatella hiwia McKnight 1977 South China Sea phylogenetic relationship taxonomy

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An inulin-type fructan CP-A from Codonopsis pilosula attenuates experimental colitis in mice by promoting autophagy-mediated inactivation of NLRP3 inflammasome

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Chinese Journal of Natural Medicines 2024年第3期22卷 249-264页

作者： ZHOU Jiangtao wang Jun wang Jiajing LI Deyun HOU Jing LI Jiankuan BAI Yun’e GAO Jianping School of Pharmaceutical Science Shanxi Medical UniversityJinzhong 030600China

Inulin-type fructan CP-A,a predominant polysaccharide in Codonopsis pilosula,demonstrates regulatory effects on immune activity and *** efficacy of CP-A in treating ulcerative colitis(UC)is,however,not *** study employed an in vitro lipopolysaccharide(LPS)-induced colonic epithelial cell model(NCM460)and an in vivo dextran sulfate sodium(DSS)-induced colitis mouse model to explore CP-A’s protective effects against experimental colitis and its underlying *** monitored the clinical symptoms in mice using various parameters:body weight,disease activity index(DAI),colon length,spleen weight,and histopathological ***,molecular markers were assessed through enzyme-linked immunosorbent assay(eLISA),quantitative real-time polymerase chain reaction(qRT-PCR),immunofluorescence(IF),immunohistochemistry(IHC),and Western blotting *** showed that CP-A significantly reduced reactive oxygen species(ROS),tumor necrosis factor-alpha(TNF-α),and interleukins(IL-6,IL-1β,IL-18)in LPS-induced cells while increasing IL-4 and IL-10 levels and enhancing the expression of Claudin-1,ZO-1,and occludin proteins in NCM460 ***,in vivo findings revealed that CPA administration markedly improved DAI,reduced colon shortening,and decreased the production of myeloperoxidase(MPO),malondialdehyde(MDA),ROS,IL-1β,IL-18,and NOD-like receptor protein 3(NLRP3)inflammasome-associated genes/proteins in UC ***-A treatment also elevated glutathione(GSH)and superoxide dismutase(SOD)levels,stimulated autophagy(LC3B,P62,Beclin-1,and ATG5),and reinforced Claudin-1 and ZO-1 expression,thereby aiding in intestinal epithelial barrier repair in colitis ***,the inhibition of autophagy via chloroquine(CQ)diminished CP-A’s protective impact against colitis in *** findings elucidate that CP-A’s therapeutic effect on experimental colitis possibly involves mitigating intestinal inflammation through autophagymediated N

关键词： Inulin-type fructan CP-A Codonopsis pilosula Ulcerative colitis NLRP3 inflammasome Autophagy

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Cavitation research with computational fluid dynamics:From euler-euler to euler-Lagrange approach

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Journal of Hydrodynamics 2024年第1期36卷 1-23页

作者： Bin Ji Zi-yang wang Huai-yu Cheng Rickard e.Bensow State Key Laboratory of Water Resources engineering and Management Wuhan UniversityWuhan430072China Department of Mechanics and Maritime Sciences Chalmers University of TechnologyGothenburgSweden

Unsteady cavitating flow often contains vapor structures with a wide range of different length scales,from micro-bubbles to large cavities,which issues a big challenge to precisely investigate its evolution mechanism by computational fluid dynamics(CFD)*** present work reviews the development of simulation methods for cavitation,especially the emerging euler-Lagrange ***,the progress of the numerical investigation of hot and vital issues is discussed,including cavitation inception,cloud cavitation inner structure and its formation mechanism,cavitation erosion,and cavitation *** is indicated that the euler-Lagrange method can determine cavitation inception point *** cloud cavitation,the euler-Lagrange method can reveal the source of microbubbles and their distribution law inside the shedding *** method also has advantages and great potential in assessing cloud cavitation-induced erosion and *** the ever-growing demands of cavitation simulation accuracy in basic research and engineering applications,how to improve the euler-Lagrange method’s stability and applicability is still an open *** further promote the application of this advanced CFD simulation technology in cavitation research,some key issues are to be solved and feasible suggestions are put forward for further work.

关键词： numerical simulation euler-euler method euler-Lagrange method bubble dynamicsgy,Gothenburg,Sweden

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Identification of the lysine and histidine transporter family in Camellia sinensis and the characterizations in nitrogen utilization

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Horticultural Plant Journal 2024年第1期10卷 273-287页

作者： Wei Huang Danni Ma Fawad Zaman Xulei Hao Li Xia e Zhang Pu wang Mingle wang Fei Guo Yu wang Dejiang Ni Hua Zhao National Key Laboratory for Germplasm Innovation&Utilization of Horticultural Crops College of Horticulture and Forestry SciencesHuazhong Agricultural UniversityWuhanHubei 430070China

In plants,the lysine and histidine transporter(LHT)family represent a class of proteins that mediate the uptake,translocation,and utilization of amino *** tea plant(Camellia sinensis)is a perennial evergreen with a relatively high level of amino ***,systematic identification and molecular characterization of the LHT gene family has rarely been reported in tea *** this study,22 CsLHTs were identified from the‘Shuchazao’genome and classified into two *** modeled three-dimensional structure and the conserved domains presented a high similarity among the LHTs ***,it was predicted that a few genes were conserved through the analysis of the physiochemical characters,structures and cis-elements in *** expression patterns in tea plants revealed that CsLHT7 was mainly expressed in the roots,and CsLHT4 and CsLHT11 exhibited relatively high expression in both the roots and ***,the expression of all three genes could be induced by organic ***,heterogeneous expression of CsLHT4,CsLHT7 and CsLHT11 in Arabidopsis thaliana decreased the aerial parts biomass compared with that in WT plants while significantly increased the rosette biomass only for CsLHT11transgenic plants versus WT ***,our results provide fundamental information about CsLHTs and potential genes in N utilization for further analysis in tea plants.

关键词： Camellia sinensis Nitrogen Lysine and histidine transporter(LHT)family

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Clinical usefulness of the baby vision test in young children and its correlation with the Snellen chart

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International Journal of Ophthalmology(english edition) 2024年第2期17卷 348-352页

作者： Ya-Lan wang Jia-Jun wang Xi-Cong Lou Han Zou Yun-e Zhao The eye Hospital of Wenzhou Medical University Hangzhou 310000Zhejiang ProvinceChina National Clinical Research Center for Ocular Diseases Wenzhou 325027Zhejiang ProvinceChina

AIM:To investigate the efficacy of a new visual acuity(VA)screening method,the baby vision test for young ***:A total 105 eyes of 65 children aged 2-8y were included in the *** testing was conducted using a standardized recognition acuity chart(Snellen visual chart:at 3 m)and the baby vision model *** baby vision device includes a screen,a near infrared camera and a *** were seated at a measured distance of 33-40 cm from a display for *** was estimated according to the highest resolution the children could *** VA data were converted to logarithm of the minimum angle of resolution(logMAR)for statistical *** VA results for each child were recorded and analyzed for ***:The mean VA measured using the Snellen visual chart was 0.62±0.32,and that assessed using the baby vision test was 0.66±*** 95%limit of agreement was-0.609 to 0.695,with 95.2%(100/105)plots within the 95%limits of *** values of the baby vision test were significantly correlated with those of the Snellen chart(R=0.274,P=0.005).CONCLUSION:The baby vision test can be used as a relatively reliable method for estimating VA in young *** new acuity assessment might be a valid predictor of optotype-measured acuity later in preverbal children.

关键词： baby vision test acuity assessment fix-and-follow system Snellen chart

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Investigations of nuclear chirality at iThemba LABS

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Frontiers of physics 2024年第2期19卷 7-38页

作者： R.A.Bark e.A.Lawrie C.Liu S.Y.wang iThemba Laboratory for Accelerator Based Sciences National Research FoundationP.O.Box 722Somerset-West 7129South Africa Department of Physics University of the Western CapePrivate Bag X177535BellvilleSouth Africa Shandong Provincial Key Laboratory of Optical Astronomy and Solar-Terrestrial environment Institute of Space SciencesShandong UniversityWeihai 264209China

Progress in the studies of chirality in atomic nuclei at iThemba LABS is *** regions of chirality,around mass 80 and 190 have been discovered using the AFRODITe array,specifically in the nuclei^(74)As,^(78,80,82)Br,^(81)Kr,and^(193,194,198)*** phenomena have been observed,including multiple chiral bands in the same nucleus,the coexistence of octupole correlations and nuclear chirality,and the coexistence of pseudo spin and nuclear *** best example of chiral degeneracy to date was found in ^(194)*** level scheme of ^(106)Ag has been revisited and interpreted in terms of two-and four-quasiparticle *** using the particle-rotor model have shown that the fingerprints of chirality in the two-quasiparticle system only can occur in an idealised model *** systems with a higher number of quasiparticles,the calculations showed that nuclear chirality can persist.

关键词： chirality high-spin states particle-rotor model

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