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Effect of deformation parameters on the austenite dynamic recrystallization behavior of a eutectoid pearlite rail steel

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International Journal of Minerals,Metallurgy and Materials 2024年第5期31卷 833-841页

作者： Haibo Feng Shaohua Li Kexiao Wang Junheng Gao Shuize Wang Haitao Zhao Zhenyu Han Yong Deng yuhe huang Xinping Ma Institute for Carbon Neutrality University of Science and Technology BeijingBeijing 100083China Institute for Steel Sustainable Technology Liaoning Academy of MaterialsShenyang 110004China Pangang Group Panzhihua Iron and Steel Research Institute Co.Ltd. Panzhihua 617000China

Understandings of the effect of hot deformation parameters close to the practical production line on grain refinement are crucial for enhancing both the strength and toughness of future rail steels.In this work,the austenite dynamic recrystallization(DRX)behaviors of a eutectoid pearlite rail steel were studied using a thermo-mechanical simulator with hot deformation parameters frequently employed in rail production lines.The single-pass hot deformation results reveal that the prior austenite grain sizes(PAGSs)for samples with different deformation reductions decrease initially with an increase in deformation temperature.However,once the deformation temperature is beyond a certain threshold,the PAGSs start to increase.It can be attributed to the rise in DRX volume fraction and the increase of DRX grain with deformation temperature,respectively.Three-pass hot deformation results show that the accumulated strain generated in the first and second deformation passes can increase the extent of DRX.In the case of complete DRX,PAGS is predominantly determined by the deformation temperature of the final pass.It suggests a strategic approach during industrial production where part of the deformation reduction in low temperature range can be shifted to the medium temperature range to release rolling mill loads.

关键词： eutectoid pearlite rail steel prior austenite grain size dynamic recrystallization single-pass hot deformation three-pass hot deformation

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Intranasal boosting with RBD-HR protein vaccine elicits robust mucosal and systemic immune responses

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Genes & Diseases 2024年第4期11卷 327-339页

作者： Li Chen Wenyan Ren Hong Lei Jiayu Wang Haiying Que Dandan Wan Aqu Alu Dandan Peng Minyang Fu Weiqi Hong yuhe huang Xiangrong Song Guangwen Lu Xiawei Wei Laboratory of Aging Research and Cancer Drug Target State Key Laboratory of Biotherapy and Cancer CenterNational Clinical Research Center for GeriatricsWest China HospitalSichuan UniversityChengduSichuan 610041China

The emergence of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)variants has decreased the efficacy of SARs-CoV-2 vaccines in containing coronavirus disease 2019(CoVID-19)over time,and booster vaccination strategies are urgently necessitated to achieve sufficient protection.Intranasal immunization can improvemucosal immunity,offer-ing protection against the infection and sustaining the spread of SARS-CoV-2.In this study,an intranasal booster of the RBD-HR vaccine after two doses of the mRNA vaccine significantly increased the levels of specific binding antibodies in serum,nasal lavage fluid,and bronchoal-veolar lavage fluid compared with only two doses of mRNA vaccine.After intranasal boosting with the RBD-HR vaccine,the levels of serum neutralizing antibodies against prototype and variant strains of SARS-Cov-2 pseudoviruses weremarkedly higher than those in mice receiving mRNA vaccine alone,and intranasal boosting with the RBD-HR vaccine also inhibited the bind-ing of RBD to hACE2 receptors.Furthermore,the heterologous intranasal immunization regimen promoted extensive memory T cell responses and activated CD103+dendritic cells in the respiratory mucosa,and potently enhanced the formation of T follicular helper cells and germinal center B cells in vital immune organs,including mediastinal lymph nodes,inguinal lymph nodes,and spleen.Collectively,these data infer that heterologous intranasal boosting with the RBD-HR vaccine elicited broad protective immunity against SARS-CoV-2 both locallyandsystemically.

关键词： Heterologous immunization Intranasal immunization mRNA vaccine SARS-CoV-2 Subunitprotein vaccine

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Synergy of heterogeneous Co/Ni dual atoms enabling selective C-O bond scission of lignin coupling with in-situ N-functionalization

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Journal of Energy Chemistry 2024年第5期92卷 16-25页

作者： Baoyu Wang Jinshu huang Hongguo Wu Ximing Yan yuhe Liao Hu Li National Key Laboratory of Green Pesticide Key Laboratory of Green Pesticide&Agricultural BioengineeringMinistry of EducationState-Local Joint Laboratory for Comprehensive Utilization of BiomassCollege of Pharmacy&Center for R&D of Fine ChemicalsGuizhou UniversityGuiyang 550025GuizhouChina Guangxi Key Laboratory of Green Chemical Materials and Safety Technology Beibu Gulf UniversityQinzhou 535011GuangxiChina Guangzhou Institute of Energy Conversion Chinese Academy of SciencesGuangzhou 510640GuangdongChina

Selective cleavage of Csp^(2)-OCH_(3)bond in lignin without breaking other types of C-O bonds followed by N-functionalization is fascinating for on-purpose valorization of biomass.Here,a Co/Ni-based dual-atom catalyst CoNiDA@NC prepared by in-situ evaporation and acid-etching of metal species from tailor-made metal–organic frameworks was efficient for reductive upgrading of various lignin-derived phenols to cyclohexanols(88.5%–99.9%yields),which had ca.4 times higher reaction rate than the single-atom catalyst and was superior to state-of-the-art heterogeneous catalysts.The synergistic catalysis of Co/Ni dual atoms facilitated both hydrogen dissociation and hydrogenolysis steps,and could optimize adsorption configuration of lignin-derived methoxylated phenols to further favor the Csp^(2)-OCH_(3)cleavage,as elaborated by theoretical calculations.Notably,the CoNi_(DA)@NC catalyst was highly recyclable,and exhibited excellent demethoxylation performance(77.1%yield)in real lignin monomer mixtures.Via in-situ cascade conversion processes assisted by dual-atom catalysis,various high-value N-containing chemicals,including caprolactams and cyclohexylamines,could be produced from lignin.

关键词： Biomass conversion Heterogeneous catalysis Lignin Dual-atom catalyst Selective C-ocleavage

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A new insight for stem cell therapy:apoptotic stem cells as a key player

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Signal Transduction and Targeted Therapy 2022年第9期7卷 3181-3183页

作者： yuhe huang Ziyi Bai Kang Zhang Laboratory of Aging Research and Cancer Drug Target State Key Laboratory of BiotherapyNational Clinical Research Center for GeriatricsWest China HospitalSichuan UniversityNo.17Block 3Southern Renmin RoadChengduSichuan 610041PR China Zhuhai International Eye Center Zhuhai People's Hospital and The First Afliated Hospital of Faculty of MedicineMacao University of Science and TechnologyZhuhaiChina

Recently,two studies on therapeutic effects of stem cell therapy were published in Signal Transduction and Target Therapy1 and Nature Communications.2These studies have shed the light on a unique aspect of stem cell therapy which involves a previously unrecognized key player,namely apoptotic cells.These two publications have elucidated how the apoptotic cells exert immunomodulatory effects in stem cell therapy in several animal models.

关键词： apo therapy Therapy

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Martensitic twinning transformation mechanism in a metastable IVB element-based body-centered cubic high-entropy alloy with high strength and high work hardening rate

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Journal of Materials Science & Technology 2022年第29期124卷 217-231页

作者： yuhe huang Junheng Gao Vassili Vorontsov Dikai Guan Russell Goodall David Dye Shuize Wang Qiang Zhu W.Mark Rainforth Iain Todd Department of Materials Science and Engineering University of SheffieldSheffield S13JDUnited Kingdom Department of Mechanical and Energy Engineering Southern University of Science and TechnologyShenzhen518055China Beijing Advanced Innovation Center for Materials Genome Engineering University of Science and Technology BeijingBeijing 100083China Department of Materials Royal School of MinesImperial College LondonLondon SW72BPUnited Kingdom

Realizing high work hardening and thus elevated strength–ductility synergy are prerequisites for the practical usage of body-centered-cubic high entropy alloys(BCC-HEAs).In this study,we report a novel dynamic strengthening mechanism,martensitic twinning transformation mechanism in a metastable refractory element-based BCC-HEA(TiZrHf)Ta(at.%)that can profoundly enhance the work hardening capability,leading to a large uniform ductility and high strength simultaneously.Different from conventional transformation induced plasticity(TRIP)and twinning induced plasticity(TWIP)strengthening mechanisms,the martensitic twinning transformation strengthening mechanism combines the best characteristics of both TRIP and TWIP strengthening mechanisms,which greatly alleviates the strengthductility trade-off that ubiquitously observed in BCC structural alloys.Microstructure characterization,carried out using X-ray diffraction(XRD)and electron back-scatter diffraction(EBSD)shows that,upon straining,α”(orthorhombic)martensite transformation,self-accommodation(SA)α”twinning and mechanicalα”twinning were activated sequentially.Transmission electron microscopy(TEM)analyses reveal that continuous twinning activation is inherited from nucleating mechanical{351}type I twins within SA“{351}”typeⅡtwinnedα”variants on{351}twinning plane by twinning transformation through simple shear,thereby accommodating the excessive plastic strain through the twinning shear while concurrently refining the grain structure.Consequently,consistent high work hardening rates of 2–12.5 GPa were achieved during the entire plastic deformation,leading to a high tensile strength of 1.3 GPa and uniform elongation of 24%.Alloy development guidelines for activating such martensitic twinning transformation strengthening mechanism were proposed,which could be important in developing new BCC-HEAs with optimal mechanical performance.

关键词： Metastable high entropy alloy Work hardening rate Martensitic transformation Self-accommodating martensite Twinning transformation

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基于电磁时间反演P范数判据的配电网故障定位

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电力系统保护与控制 2024年第3期52卷 74-82页

作者：刘青黄玉河王宇付瑶王乐之西安科技大学电气与控制工程学院陕西西安710054

目前电磁时间反演(electromagnetic time reversal,EMTR)多应用在单一线路故障定位,且现有判据在高阻抗接地情况下效果不理想。针对上述问题,基于EMTR故障定位原理和均匀传输线理论推导了传播过程中线路故障信号与测量信号的传递函数,... 详细信息

目前电磁时间反演(electromagnetic time reversal,EMTR)多应用在单一线路故障定位,且现有判据在高阻抗接地情况下效果不理想。针对上述问题,基于EMTR故障定位原理和均匀传输线理论推导了传播过程中线路故障信号与测量信号的传递函数,根据传递函数的相关性提出了P范数判据。利用ATP-EMTP搭建10 kV配电网线路,对比了2范数与P范数判据在复杂配电网中的定位性能,并验证了所提判据在混合配电网线路的适用性。最后,分析了配电网发生低阻抗及高阻抗接地故障下P范数判据的鲁棒性。仿真结果表明,该方法在过渡电阻高达3 kΩ的情况下能准确定位,且定位精度高,受噪声、故障类型和采样频率的影响小。

关键词：电磁时间反演传递函数 P范数配电网故障定位高阻抗接地

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响应曲面法优化甲烷水蒸气重整制氢工况参数

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石油学报（石油加工） 2024年第3期40卷 708-717页

作者：黄兴马强武健玮王雨荷陈磊姚鑫华北理工大学冶金与能源学院河北唐山063210 东北大学冶金学院辽宁沈阳110819 华北理工大学电气工程学院河北唐山063210 唐山创元方大电气有限责任公司河北唐山063000

基于Chemkin的蜂窝整体式反应器计算甲烷水蒸气重整中的甲烷转化率和氢气产率,得到不同工况参数(反应器温度、水蒸气与甲烷的摩尔比(水/碳比)和压力)对甲烷转化率和氢气产率的影响。采用响应曲面法以及Box-Behnken-Design模型对不同工... 详细信息

基于Chemkin的蜂窝整体式反应器计算甲烷水蒸气重整中的甲烷转化率和氢气产率,得到不同工况参数(反应器温度、水蒸气与甲烷的摩尔比(水/碳比)和压力)对甲烷转化率和氢气产率的影响。采用响应曲面法以及Box-Behnken-Design模型对不同工况参数进行优化,建立以氢气产率为响应目标的响应模型。结果表明,水/碳比和反应器温度对氢气产率的影响最为显著。当反应器温度为1079.65 K、水/碳比为3.94、压力为0.11 MPa时,模拟3次的平均氢气产率为80.58%。采用化学反应过程仿真与数值结果预测相结合的方法,显著减少了仿真时间,提高了计算效率和精度。

关键词：蜂窝整体式反应器制氢甲烷水蒸气重整 Chemkin模拟响应曲面法参数优化

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Evaluation of CMPAS precipitation products over Sichuan,China

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Atmospheric and Oceanic Science Letters 2022年第2期15卷 47-53页

作者： Shiying Li Xiaolong huang Wei Wu Bing Du yuhe Jiang Sichuan Meteorological Observation and Data Center Heavy Rain and Drought-Flood Disasters in Plateau and Basin Key Laboratory of Sichuan ProvinceChengduChina

高质量和高分辨率的降水产品在天气预报,数值模式模拟和气象防灾减灾方面起着重要的作用.本文利用四川地区高密度的地面降水传感器观测数据,比较CMPAS四种不同时空尺度的降水实况分析产品,评估CMPAS的融合准确性与在四川地区的适用性.... 详细信息

高质量和高分辨率的降水产品在天气预报,数值模式模拟和气象防灾减灾方面起着重要的作用.本文利用四川地区高密度的地面降水传感器观测数据,比较CMPAS四种不同时空尺度的降水实况分析产品,评估CMPAS的融合准确性与在四川地区的适用性.研究表明:四种CMPAS降水产品都在四川盆地内精度较高,攀西地区和川西高原次之.随着降水量的增加,产品的误差也随之增加.CMPAS在夏秋两季对降水量高估,在春冬两季对降水量低估.总而言之,CMPAS在四川盆地内与观测数据的融合准确性较高.由于高原地区气象观测站点数量不足且观测数据受复杂地形和气候条件影响较大,CMPAS在高原地区的适用性检验仍需进一步研究.

关键词：多元降水融合产品高分辨率降水中国区域多源融合实况分析产品适用性评估

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A small microring array that performs large complex-valued matrix-vector multiplication

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Frontiers of Optoelectronics 2022年第2期15卷 1-15页

作者： Junwei Cheng yuhe Zhao Wenkai Zhang Hailong Zhou Dongmei huang Qing Zhu Yuhao Guo Bo Xu Jianji Dong Xinliang Zhang Wuhan National Laboratory for Optoelectronics School of Optical and Electronic InformationHuazhong University of Science and TechnologyWuhan 430074China Photonics Research Centre Department of Electronic and Information EngineeringThe Hong Kong Polytechnic UniversityHong Kong 999077China The Hong Kong Polytechnic University Shenzhen Research Institute Shenzhen 518057China Photonics Research Centre Department of Electrical EngineeringThe Hong Kong Polytechnic UniversityHong Kong 999077China Institute of Strategic Research Huawei TechnologiesShenzhen 518129China

As an important computing operation,photonic matrix-vector multiplication is widely used in photonic neutral networks and signal processing.However,conventional incoherent matrix-vector multiplication focuses on real-valued operations,which cannot work well in complex-valued neural networks and discrete Fourier transform.In this paper,we propose a systematic solution to extend the matrix computation of microring arrays from the real-valued field to the complex-valued field,and from small-scale(i.e.,4×4)to large-scale matrix computation(i.e.,16×16).Combining matrix decomposition and matrix partition,our photonic complex matrix-vector multiplier chip can support arbitrary large-scale and complex-valued matrix computation.We further demonstrate Walsh-Hardmard transform,discrete cosine transform,discrete Fourier transform,and image convolutional processing.Our scheme provides a path towards breaking the limits of complex-valued computing accelerator in conventional incoherent optical architecture.More importantly,our results reveal that an integrated photonic platform is of huge potential for large-scale,complex-valued,artificial intelligence computing and signal processing.

关键词： Photonic matrix-vector multiplication Complex-valued computing Microring array Signal/image processing

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中国6~23月龄婴幼儿不同辅食物性构建及可接受性

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卫生研究 2024年第3期53卷 396-402页

作者：贺梦璐魏艳丽吴琼黄聪慧李天童刘宇赫周雪飞原晓蓉孙静中国疾病预防控制中心营养与健康所北京100050 首都儿科研究所北京100020

目的构建6~23月龄婴幼儿辅食物性指标,观察不同月龄婴幼儿辅食物性接受性。方法根据国内外相关婴幼儿辅食喂养指南、共识及相关资料,结合当前中国婴幼儿生长发育特点,构建6~23月龄婴幼儿喂养辅食物性指标。在南北方各选取1个省份,每省选... 详细信息

目的构建6~23月龄婴幼儿辅食物性指标,观察不同月龄婴幼儿辅食物性接受性。方法根据国内外相关婴幼儿辅食喂养指南、共识及相关资料,结合当前中国婴幼儿生长发育特点,构建6~23月龄婴幼儿喂养辅食物性指标。在南北方各选取1个省份,每省选择1个城市和1个农村作为观察点,采用分层随机抽样原则,共抽取240名婴幼儿进行可接受性研究。选择5类12种常见食材制作辅食物性工具包,指导家长按相应月龄段辅食物性进行辅食家庭制作、单一/混合喂养接受性观察并记录。结果构建6月龄、7~8月龄、9~11月龄、12~17月龄及18~23月龄共5个月龄段辅食物性指标。婴幼儿看护人能够按构建的辅食物性指标要求制作相应月龄段辅食,6~23月龄5个月龄段单一辅食物性可接受度分别为98.3%、98.7%、99.8%、96.9%和97.5%。7~23月龄4个月龄段混合辅食物性可接受度分别为98.3%、99.6%、93.8%和97.5%。结论构建的不同月龄段辅食物性指标可实现家庭制作,婴幼儿接受性良好。

关键词：婴幼儿喂养辅食物性质地性状可接受性

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