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Effect of ephedrine hydrochloride on regulation of body fluid metabolism and AQP1 and AQP2 in a rabbit model of mechanical ventilation

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Journal of Traditional Chinese Medical Sciences 2019年第4期6卷 337-346页

作者： Shujing Zhang Yan Sun Yushan Gao Lu Zhou Zhenyi Wang Xiaolei liu Pengfei Kang Fengjie Zheng Lei Ni yuhang li School of Traditional Chinese Medicine Beijing University of Chinese MedicineBeijing 102488China

Objective:Ephedrine hydrochloride(EH)is a major component from Ephedra sinica STAPF,which is used as a traditional Chinese herbal *** study was designed to investigate the effect of EH on water metabolism and further explore the relevant signaling pathway of body fluid regulation in“lung governing regulation of water passage”using a rabbit model of mechanical *** molecular mechanism of the EH effect in the kidney was also ***:Rabbits were randomly divided into a control group,model group,EH group,and dexmedetomidine hydrochloride(DH)*** volume was measured by the intubation method and pathologic changes in lung and renal tissue were measured by hematoxylin and eosin *** oxide(NO)production in lung,serum,and kidney were analyzed using chemical *** EliSA was used to analyze angiotensin II(Ang II),antidiuretic hormone(ADH),prostaglandin E2(PGE2),atrial natriuretic peptide(ANP),and endothelin-1(ET-1)levels in the lung,serum,and ***-1(AQP1)and aquaporin-2(AQP2)mRNA and protein expression in the kidney was determined using qRT-PCR and ***:EH significantly inhibited the decrease in the total urine volume in the third and fourth stages,and displayed significant regulatory effects on NO,Ang II,ADH,PGE2,ANP,and ET-1 in serum,lung,and renal tissues compared with the model *** the kidney,AQP1 and AQP2 mRNA and protein expression in the EH group were remarkably downregulated compared with the model ***:EH exerted a regulatory effect on water metabolism by diffusing the lung and increased urine volume in the rabbit model,which was consistent with the decrease in kidney AQP1 and AQP2 expression levels that led to an increase in urine *** could assist with DH to exert a protective effect on the clinical application of mechanical ventilation.

关键词： Mechanical ventilation Ephedrine hydrochloride Dexmedetomidine hydrochloride Humoral regulation

Specialized digestive adaptations within the hindgut of a colobine monkey

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The Innovation 2022年第2期3卷 103-109页

作者： Rui liu Katherine Amato Rong Hou Andres Gomez Derek W.Dunn Jun Zhang Paul A.Garber Colin A.Chapman Nicoletta Righini Gang He Gu Fang yuhang li Baoguo li Songtao Guo Shaanxi Key Laboratory for Animal Conservation School of Life SciencesNorthwest UniversityXi’an 710069China Department of Anthropology Northwestern UniversityEvanstonIL 60208USA Department of Animal Science University of Minnesota Twin CitiesSt.PaulMN 55455USA Department of Anthropology and Program in EcologyEvolution and Conservation BiologyUniversity of Illinois at Urbana-ChampaignUrbana-ChampaignIL 61801USA Center for the Advanced Study of Human Paleobiology Department of AnthropologyThe George Washington UniversityWashingtonDC 20037USA School of life Sciences University of KwaZulu-NatalScottsvillePietermaritzburg 3209South Africa Instituto de Investigaciones en Comportamiento Alimentario y Nutrición(IICAN) Universidad de Guadalajara49000 Ciudad GuzmánJaliscoMexico

In mammal herbivores,fiber digestion usually occurs predominantly in either the foregut or the *** of mechanisms showing synergistic function in both gut regions for the digestion of fiber and other nutrients in wild mammals are rare because it requires integrative study of anatomy,physiology,and gut *** monkeys(Colobinae)are folivorous,with high-fiber foods fermented primarily in their foreguts.

关键词： anatomy gut primarily

Stretchable magnesium-air battery based on dual ions conducting hydrogel for intelligent biomedical applications

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InfoMat 2023年第3期5卷 45-57页

作者： Xingcan Huang Yiming liu Wooyoung Park Zhao Zhao Jiyu li Chee Kent lim Tsz Hung Wong Chun Ki Yiu Yuyu Gao Jingkun Zhou Huli ling Zhao Jian li Binbin Zhang Ya Huang Rui Shi Dengfeng li Jiaying Mo Jinpei Wang Chao Zhang yuhang li Zuankai Wang Xinge Yu Department of Biomedical Engineering City University of Hong KongKowloonHong Kongthe People's Republic of China Institute of Solid Mechanics Beihang University(BUAA)Beijingthe People's Republic of China Hong Kong Center for Cerebra-Cardiovascular Health Engineering Hong Kong Science ParkKowloonNew TerritoriesHong Kongthe People's Republic of China School of Energy and Environment City University of Hong KongKowloonHong Kongthe People's Republic of China Department of Mechanical Engineering City University of Hong KongKowloonHong Kongthe People's Republic of China Aircraft and Propulsion Laboratory Ningbo Institute of Technology Beihang University(BUAA)Ningbothe People's Republic of China Shenzhen Research Institute City University of Hong Kong Shenzhenthe People's Republic of China

Flexible and bio-integrated electronics have attracted great attention due to their enormous contributions to personalized medical *** sources,serving as one of the most important components,have been suffering from many problems,including deficient biocompatibility,poor stretchability,and unstable electrical outputs under deformed conditions,which limits the practical applications in flexible and bio-integrated ***,we reported a fully stretchable magnesium(Mg)–air battery based on dual-ions-conducting hydrogels(SDICH).The high-performance battery enables long-term operation with lighting 120 lighting emitting diodes(LEDs)for over 5 *** from the advanced materials and mechanical designs,the battery exhibits stability electrical outputs under stretching,which allows to operate ordinarily under various mechanical deformations without performance ***,the great biocompatibility of the battery offers great opportunity for biomedical applications,which is demonstrated by a self-adaption wound dressing *** in vitro and in vivo results prove that the self-adaption wound dressing can effectively prevent wound inflammation and promote wound *** exploiting thermal feedback mechanics,the system can adjust antibiotic release rate and dosage spontaneously according to the real-time wound *** proposed fully stretchable Mg-air battery and self-adaption wound dressing display great potential in skin-integrated electronics and personalized medicine.

关键词： bioelectronics flexible electronics Mg-air battery stretchable battery wound healing

CO_(2)响应型聚合物光催化剂的制备及其活性研究

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湖南大学学报（自然科学版） 2024年第12期51卷 195-202页

作者：李润方静李宇航湖南大学材料科学与工程学院湖南长沙410082

报道了两种CO_(2)响应型聚合物光催化剂DTS-LP1和BT-LP2,这两种光催化剂可以在CO_(2)的调节下改变亲水性,实现在水溶液中均匀分散.与此同时,反应后通过排出CO_(2)可以快速分离出光催化剂,从而实现光催化剂的回收利用.另外,通过电化学测... 详细信息

报道了两种CO_(2)响应型聚合物光催化剂DTS-LP1和BT-LP2,这两种光催化剂可以在CO_(2)的调节下改变亲水性,实现在水溶液中均匀分散.与此同时,反应后通过排出CO_(2)可以快速分离出光催化剂,从而实现光催化剂的回收利用.另外,通过电化学测试分析了两种聚合物的光电流响应和电化学阻抗,其中,DTS-LP1具有更大的光电流响应强度和较低的电荷转移电阻.采用循环伏安法测试得到了两种聚合物的能带结构,结果显示均满足光催化硫化物氧化条件.当采用DTS-LP1和BT-LP2为光催化剂时,10 h内光催化硫化物氧化的转化率分别为97%和42%,表明聚合物光催化剂具有优异的催化性能.

关键词：硫化物氧化 CO_(2)响应共轭聚合物光催化剂回收

2022年1月8日M_(S)6.9青海门源地震震前三维地壳变形与应变分配

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地球物理学报 2023年第2期66卷 576-588页

作者：李长军郝明李煜航宋尚武中国地震局第二监测中心西安710054 南方海洋科学与工程广东省实验室(珠海) 广东珠海519080

2022年01月08日在祁连山断裂带中东段的青海门源县发生了M_(S)6.9强震,然而,迄今为止对于该地区的三维地壳变形特征和强震孕育背景鲜有研究.本文基于高精度的GPS和水准等大地测量资料,厘定了该区域主要活动断裂的滑动速率,并分析了此次... 详细信息

2022年01月08日在祁连山断裂带中东段的青海门源县发生了M_(S)6.9强震,然而,迄今为止对于该地区的三维地壳变形特征和强震孕育背景鲜有研究.本文基于高精度的GPS和水准等大地测量资料,厘定了该区域主要活动断裂的滑动速率,并分析了此次地震之前的三维地壳变形特征和强震孕育背景.研究结果表明,(1)祁连山断裂带中东段地壳变形呈现出较强的左旋剪切和缩短变形,且地壳缩短主要以垂直隆升的形式实现;(2)托莱山断裂的走滑、缩短和垂直速率分别为2.5±0.3 mm·a^(-1)、1.3±0.4 mm·a^(-1)和1.2±0.6 mm·a^(-1),高于其北侧的民乐-大马营断裂的1.1±0.3 mm·a^(-1)、0.8±0.3 mm·a^(-1)和0.5±0.5 mm·a^(-1),冷龙岭断裂的走滑和缩短速率分别为3.1±0.7 mm·a^(-1)和3.0±0.6 mm·a^(-1),结合应变率场,表明该区域地壳变形满足连续-弥散变形模式;(3)此次门源地震震前剪应变和压性面应变明显积累,其中部分压性面应变被2016 M_(S)6.4地震所释放,而在托莱山和冷龙岭断裂以南地区垂直变形并不显著,震前应变持续增加.此外,GPS速度剖面揭示出托莱山断裂存在明显的震间闭锁,其闭锁深度为15.0±7.8 km,表明其具有发生强震的背景.

关键词： 2022年M_(S)6.9门源地震三维地壳变形应变分配 GPS和水准观测

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利用人工植林削减古塔风荷载的风洞试验

工程科学与技术 2023年第3期55卷 58-68页

作者：邓扬李雨航李爱群北京建筑大学土木与交通工程学院北京100044 北京未来城市高精尖创新中心北京100044 东南大学土木工程学院江苏南京211189

高耸古木塔是世界建筑文化遗产的重要组成部分,也是中国古代木建筑的典范。外部风荷载作用是影响古木塔结构安全的重要因素,人工植林可改变古木塔的风场环境,实现削减风荷载作用并缓解风致结构损伤的目的。本文开展了古木塔的风洞试验研... 详细信息

高耸古木塔是世界建筑文化遗产的重要组成部分,也是中国古代木建筑的典范。外部风荷载作用是影响古木塔结构安全的重要因素,人工植林可改变古木塔的风场环境,实现削减风荷载作用并缓解风致结构损伤的目的。本文开展了古木塔的风洞试验研究,验证了人工植林技术削减古木塔风荷载作用的可行性;以中国山西应县木塔为原型设计并制作了1∶50的大比例刚性木塔模型,开展了在树木遮挡下木塔的风洞试验,考察了木塔的表面风压分布特征;同时,计算了不同树木高度、树木距木塔距离和树木布置宽度等条件下木塔的层间力与层倾覆弯矩,并分析了基底剪力与弯矩的减小率。结果表明:在遮挡高度范围内,人工植林可有效减小木塔表面风压;同时,在高于遮挡范围的侧风面与背风面,树木也会一定程度地降低木塔表面风压。人工植林树木高度是影响木塔风荷载削减效果的关键条件,树木越高,风荷载减小效果越好。分析表明,人工植林应选择高大乔木,并布置在距木塔较近的区域,且树木布置间距应尽量宽。本文通过风洞试验验证了利用人工植林削弱高耸古木塔的风压与风荷载的可行性,提供了缓解高耸古木塔风荷载作用及风致损伤的新思路,可为高耸古木塔的结构保护提供技术选择。

关键词：木结构人工植林风效应风洞试验风压

One feature of the activated southern Ordos block:the Ziwuling small earthquake cluster

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Geodesy and Geodynamics 2014年第3期5卷 16-22页

作者： li yuhang Wang Qingliang Cui Duxin Hao Ming Ji lingyun Qin Shanlan Institute of Geology China Earthquake Administration Second Crust Monitoring and Application Center China Earthquake Administration

Small earthquakes （Ms〉2.0） have been recorded from 1970 to the present day and reveal a significant diffrence in seismicity between the stable Ordos block and its active surrounding area. The southern Ordos block is a conspicuous small earthquake belt clustered and isolated along the NNW direction and extends to the inner stable Ordos block; no active fault can match this small earthquake cluster. In this paper, we analyze the dynamic mechanism of this small earthquake cluster based on the GPS velocity field （from 1999 to 2007） , which are mainly from Crustal Movement Observation Network of China （CMONOC） with respect to the north and south China blocks. The principal direction of strain rate field, the expansion ratefield, the maximum shear strain rate, and the rotation rate were constrained using the GPS velocity field. The results show that the velocity field, which is bounded by the small earthquake cluster from Tongchuan to Weinan, differs from the strain rate field, and the crustal deformation is left-lateral shear. This left-lateral shear belt not only spatially coincides with the Neo-tectonic belt in the Weihe Basin but also with the NNW small earthquake cluster （the Ziwuling small earthquake cluster）. Based on these studies, we speculate that the NNW small earthquake cluster is caused by left-lateral shear slip, which is prone to strain accumulation. When the strain releases along the weak zone of structure, small earthquakes diffuse within its upper crust. The maximum principal compression stress direction changed from NE-SW to NEE-SWW, and the former reverse faults in the southwestern margin of the Ordos block became a left-lateral strike slip due to readjustment of the tectonic stress field after the middle Pleistocene. The NNW Neo-tectonie belt in the Weihe Basin, the different movement character of the inner Weihe Basin （which was demonstrated through GPS measurements） anti the small earthquake cluster belt reflect the activated southern margin of the

关键词： Weihe Basin small earthquake cluster tectonic background strain rate GPS measurement

我国居民数字消费行为实证分析——基于微观调查数据

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商业经济研究 2021年第12期 43-46页

作者：李雨杭广西大学商学院广西南宁530004

随着2020年新冠肺炎疫情的暴发,线下消费受到极大冲击,线上渠道份额快速提升,这使得数字消费在我国居民日常消费过程中的地位日益重要。因此,深入探究我国居民数字消费行为,对于科学引导消费行为、促进消费增长而言意义重大。故而本文... 详细信息

随着2020年新冠肺炎疫情的暴发,线下消费受到极大冲击,线上渠道份额快速提升,这使得数字消费在我国居民日常消费过程中的地位日益重要。因此,深入探究我国居民数字消费行为,对于科学引导消费行为、促进消费增长而言意义重大。故而本文基于微观调查数据,对我国居民数字消费行为进行实证研究。结果显示:性别的差异对数字化消费感知易用性具有显著影响,而对数字化消费感知有用性影响较小;消费者的网络操作经验、数字化商品质量等因素均对消费者数字化消费行为有影响;消费者在网购过程中通常会重点关注经济风险、健康风险等因素。

关键词：数字化消费消费行为微观数据网购性别

利用GPS数据反演青藏高原东北缘主要活动断裂滑动速率

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地球科学（中国地质大学学报） 2015年第10期40卷 1767-1780页

作者：李煜航崔笃信郝明中国地震局地质研究所北京100029 中国地震局第二监测中心陕西西安710054

GPS测量可以提供高精度的时空图像,但前任对比研究尚未深入.通过使用线性球面块体模型理论,在前人针对活动块体研究的基础上,建立青藏高原东北缘地区三维块体几何模型.以1999—2007年的GPS水平速度场数据作为约束,反演得到青藏高原东北... 详细信息

GPS测量可以提供高精度的时空图像,但前任对比研究尚未深入.通过使用线性球面块体模型理论,在前人针对活动块体研究的基础上,建立青藏高原东北缘地区三维块体几何模型.以1999—2007年的GPS水平速度场数据作为约束,反演得到青藏高原东北缘的主要活动断裂长期滑动速率和广义海原断裂带的空间亏损滑动分布及其耦合变化.上述结果为青藏高原东北缘现今运动变形的动力学和强震中-长期危险性预测研究提供了约束和参考.

关键词：青藏高原东北缘线性球面块体模型 GPS 断层滑动速率