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Distinguished biological adaptation architecture aggravated population differentiation of Tibeto-Burman-speaking people

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Journal of Genetics and Genomics 2024年第5期51卷 517-530页

作者： Yuntao Sun Mengge wang Qiuxia Sun Yan Liu Shuhan Duan Zhiyong wang Yunyu Zhou Jun Zhong yuguo Huang Xinyu Huang Qingxin Yang Xiangping Li Haoran Su Yan Cai Xiucheng Jiang Jing Chen Jiangwei Yan Shengjie Nie Liping Hu Junbao Yang Renkuan Tang Chuan-Chao wang Chao Liu Xiaohui Deng Libing Yun Guanglin He West China School of Basic Science&Forensic Medicine Sichuan UniversityChengduSichuan 610041China Institute of Rare Diseases West China Hospital of Sichuan UniversitySichuan UniversityChengduSichuan 610000China Center for Archaeological Science Sichuan UniversityChengduSichuan 610000China Faculty of Forensic Medicine Zhongshan School of MedicineSun Yat-sen UniversityGuangzhouGuangdong 510275China Guangzhou Forensic Science Institute GuangzhouGuangdong 510055China Department of Forensic Medicine College of Basic MedicineChongqing Medical UniversityChongqing 400331China School of Clinical Medical Sciences North Sichuan Medical CollegeNanchongSichuan 637100China School of Basic Medical Sciences North Sichuan Medical CollegeNanchongSichuan 637100China School of Forensic Medicine Kunming Medical UniversityKunmingYunnan 650500China School of Stomatology North Sichuan Medical CollegeNanchongSichuan 637100China Department of Medical Laboratory North Sichuan Medical CollegeNanchongSichuan 637007China School of Life Sciences Xiamen UniversityXiamenFujian 361005China Anti-Drug Technology Center of Guangdong Province GuangzhouGuangdong 510230China School of Forensic Medicine Shanxi Medical UniversityJinzhongShanxi030600China

Tibeto-Burman(TB)people have endeavored to adapt to the hypoxic,cold,and high-UV high-altitude environments in the Tibetan Plateau and complex disease exposures in lowland rainforests since the late Paleolithic period.However,the full landscape of genetic history and biological adaptation of geographically diverse TB-speaking people,as well as their interaction mechanism,remain unknown.Here,we generate a whole-genome meta-database of 500 individuals from 39 TB-speaking populations and present a comprehensive landscape of genetic diversity,admixture history,and differentiated adaptative features of geographically different TB-speaking people.We identify genetic differentiation related to geography and language among TB-speaking people,consistent with their differentiated admixture process with incoming or indigenous ancestral source populations.A robust genetic connection between the Tibetan-Yi corridor and the ancient Yellow River people supports their Northern China origin hypothesis.We finally report substructure-related differentiated biological adaptative signatures between highland Tibetans and Loloish speakers.Adaptative signatures associated with the physical pigmentation(EDAR and SLC24A5)and metabolism(ALDH9A1)are identified in Loloish people,which differed from the high-altitude adaptative genetic architecture in Tibetan.TB-related genomic resources provide new insights into the genetic basis of biological adaptation and better reference for the anthropologically informed sampling design in biomedical and genomic cohort research.

关键词： Tibeto-Burman people Geneticprofile Natural selection Geneticdiversity Biological adaptation

乡贤圭臬与民族英雄:台湾地区福建同乡会对郑成功形象的双重阐述

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台湾研究集刊 2024年第3期 129-140页

作者：王玉国厦门大学台湾研究院福建厦门361005 两岸关系和平发展协同创新中心福建厦门361005

台湾地区光复后,闽籍人士陆续在台湾地区成立同乡组织、创办同乡刊物。截至2021年底,台湾地区共有84家福建同乡会,创办31种福建同乡刊物。这些同乡组织积极展示郑成功相关史迹,视其为乡贤圭臬,还举办郑成功诞辰纪念活动、出版纪念专刊,... 详细信息

台湾地区光复后,闽籍人士陆续在台湾地区成立同乡组织、创办同乡刊物。截至2021年底,台湾地区共有84家福建同乡会,创办31种福建同乡刊物。这些同乡组织积极展示郑成功相关史迹,视其为乡贤圭臬,还举办郑成功诞辰纪念活动、出版纪念专刊,颂扬郑成功收复中国台湾的丰功伟绩,奉其为民族英雄。在台湾地区福建同乡心目中,郑成功兼具福建乡贤和民族英雄的双重形象。

关键词：福建同乡会郑成功形象乡贤圭臬民族英雄

Enlightenment of Successful Experience of Rural Tourism in South Korea to Rural Tourism in Tai'an City

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Asian Agricultural Research 2022年第1期14卷 32-37,51页

作者： Xiu LI Xia wang yuguo wang Taishan University Tai'an 271000 China

To revitalize rural tourism and improve the quality of life of rural residents,the successful experience of rural tourism in South Korea is used for reference,with an important significance for promoting the development of rural tourism in Tai'an City.In this paper,three successful rural tourism cases of South Korea(Shuchuan,Hannong Village,Xinli Mupianwa Village)are analyzed first,and their successful experience is summarized.On the basis of accurately grasping current situation and problems of rural tourism development in Tai'an City,the countermeasures of promoting the development of rural tourism in Tai'an City are proposed:mobilizing the enthusiasm of villagers,multi-channel access to funds,diversified talent cultivation methods,product marketing system,and rural tourism management system.

关键词： Rural tourism Problems and current situation South Korea's successful experience

Chinese Society of Cardiology guidelines on the diagnosis and treatment of adult fulminant myocarditis

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Science China(Life Sciences) 2024年第5期67卷 913-939页

作者： Chinese Society of Cardiology,Chinese Medical Association,Writing Group Jiangang Jiang Hongyang Shu Dao Wen wang Rutai Hui Chenze Li Xiao Ran Hong wang Jing Zhang Shaoping Nie Guanglin Cui Dingcheng Xiang Qun Shao Shengyong Xu Discussion experts:Ning Zhou Yuming Li Wei Gao yuguo Chen Yuan Bian Guoping wang Liming Xia Yan wang Chunxia Zhao Zhiren Zhang Yuhua Zhao Jianan wang Shaoliang Chen Hong Jiang Jing Chen Xianjin Du Mao Chen Yinxian Sun Sheng Li Hu Ding Xueping Ma Hesong Zeng Li Lin Shenghua Zhou Likun Ma Ling Tao Juan Chen Yiwu Zhou Xiaomei Guo 不详 Tongji Hospital Tongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Fuwai Hospital National Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100037China Zhongnan Hospital of Wuhan University Wuhan 430062China Fuwai Huazhong Cardiovascular Hospital Zhengzhou 450003China Beijing Anzhen Hospital Capital Medical UniversityBeijing 100029China Guangzhou General Hospital of Guangzhou Military Command Guangzhou 510010China Harbin Medical University Cancer Hospital Harbin 150081China Union Hospital Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100730China Taida Hospital Tianjin 300457China Peking University Third Hospital Beijing 100191China Qilu Hospital of Shandong University Jinan 250012China Kanghua Hospital DongguanGuangzhou 523080China Second Affiliated Hospital Zhejiang University School of Medicine Hangzhou 310003China Nanjing First Hospital Nanjing Medical UniversityNanjing 210006China Renmin Hospital of Wuhan University Wuhan 430060Wuhan West China Hospital Sichuan UniversityChengdu 610044China First Hospital of China Medical University Shenyang 110002China General Hospital of Ningxia Medical University Yinchuan 750003China The Second Xiangya Hospital Central South UniversityChangsha 410012China The First Affiliated Hospital of USTC University of Science and Technology of ChinaHefei 230002China The First Affiliated Hospital of Air Force Medical University Xi’an 710032China Central Hospital of Wuhan City Wuhan 430014China Tongji Medical College Huazhong University of Science and TechnologyWuhan 430030China

Fulminant myocarditis is an acute diffuse inflammatory disease of myocardium.It is characterized by acute onset,rapid progress and high risk of death.Its pathogenesis involves excessive immune activation of the innate immune system and formation of inflammatory storm.According to China’s practical experience,the adoption of the“life support-based comprehensive treatment regimen”(with mechanical circulation support and immunomodulation therapy as the core)can significantly improve the survival rate and long-term prognosis.Special emphasis is placed on very early identification,very early diagnosis,very early prediction and very early treatment.

关键词： fulminant myocarditis guidelines life support-based comprehensive treatment regimen diagnosis treatment cytokine storm overactivation of immunity

Selenium uptake and simultaneous catalysis of sulfite oxidation in ammonia-based desulfurization

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Journal of Environmental Sciences 2021年第5期33卷 207-218页

作者： Qiangwei Li yuguo wang Lei Xing Tieyue Qi Lin Zhang Jie Liu Shihan Zhang Yongliang Ma Lidong wang Hebei Key Lab of Power Plant Flue Gas Multi-Pollutants Control Department of Environmental Science and EngineeringNorth China Electric Power UniversityBaoding071003PR China MOE Key Laboratory of Resources and Environmental Systems Optimization North China Electric Power UniversityBeijing102206P.R.China College of Environment Zhejiang University of TechnologyHangzhou 310014China School of Environment Tsinghua UniversityBeijing 100084China

Accelerating the(NH_4)_(2)SO_(3) oxidation gives rise to the reclaiming of byproduct, while there are secondary environmental risks from reduction of the coexisted selenium species by sulfite. In this study, a bi-functional Co-SBA-15-SH, were synthesized through Co impregnation and sulfhydryl(-SH) decoration, which can simultaneously uptake Se and accelerate sulfite oxidation efficiently. Meanwhile, the adsorption kinetics and migration mechanism of Se species were revealed through characterization and density functional calculations, with maximum adsorption capacity of 223 mg/g. The inhibition of Se~0 re-emission and poisonous effect of Se on sulfite oxidation was also investigated. Using the findings of this study, the ammonia desulfurization can be improved by enabling purification of the byproduct and lowering the toxicity of effluent by removing toxic pollutants.

关键词： Selenium Adsorption Re-emission Sulfite oxidation Catalyst

FEM Simulation of Single-Grit Grinding on a 2.5D Woven Composite

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Transactions of Tianjin University 2017年第6期23卷 538-546页

作者： yuguo wang Chao Ding Bin Lin Key Laboratory of Advanced Ceramic and Machining Technology of Ministry of Education Tianjin UniversityTianjin 300350China

Single-grit grinding of a 2.5D woven composite was investigated by the finite-element method(FEM) using a unit-cell model. According to our hypotheses, the axis of the warp yarn was a sinusoidal curve and the cross section of the weft yarn was shaped like a biconvex lens. AVUMAT subroutine was used to construct the constitutive model of the 2.5D woven composite. The grinding process of the composite was analyzed using an FEM simulation with the ABAQUS/Explicit software. A validation experiment was also carried out. The simulation results showed that a grinding crack was well simulated. Furthermore, the junctions between the warp yarn and weft yarn were found to be seriously damaged and cracks were observed to extend outward along the warp fiber during grinding, in good agreement with the experimental results. In addition,the strain of weft yarns was obviously greater than that of warp yarns when the grinding direction was perpendicular to the weft yarns and parallel to the axis of the warp yarns.These results demonstrate that the mesostructure strongly influences the grinding damage inflicted on woven composites.

关键词： Single-grit grinding Finite element Unit cell 2.5D woven composite

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通用型移液及自动化平台的调度算法研究

华中科技大学学报（自然科学版） 2024年第5期52卷 130-135页

作者：田浩然程文播王继帅唐玉国复旦大学工程与应用技术研究院上海200433 中国科学院苏州生物医学工程技术研究所中国科学院生物医学检验技术重点实验室江苏苏州215163 天津国科医疗科技发展有限公司天津300399

针对通用型移液平台任务低延迟约束和及时调度的问题,首先参考计算机操作系统作业调度的相关研究,提出基于任务延迟时间的动态优先级的任务调度算法;然后通过数据实验对比采用五种动态优先级函数的调度算法,并与固定优先级调度算法对比... 详细信息

针对通用型移液平台任务低延迟约束和及时调度的问题,首先参考计算机操作系统作业调度的相关研究,提出基于任务延迟时间的动态优先级的任务调度算法;然后通过数据实验对比采用五种动态优先级函数的调度算法,并与固定优先级调度算法对比;最后基于随机项目集比较不同动态优先级函数运行时的平均相对任务延迟结果.研究结果表明:采用Leaky ReLU函数作为动态优先级函数的调度算法性能最优,其服务能力比采用固定优先级时高14.47%.

关键词：通用型移液及自动化平台调度动态优先级平均相对任务延迟

温压炸药近爆作用下RC梁破坏特征和毁伤规律试验研究

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兵工学报 2024年第3期45卷 864-874页

作者：刘举张国凯王振姚箭李杰于思远纪玉国南京理工大学机械工程学院江苏南京210094 陆军工程大学爆炸冲击防灾减灾国家重点实验室江苏南京210007

作为一种高能量密度炸药,温压炸药的爆炸毁伤效应及毁伤机理有别于传统炸药。结合敞开空间温压炸药爆炸冲击波及热效应试验,研究温压炸药爆炸冲击波特征及传播规律,采用高速摄像技术和光纤多谱线测温技术分析爆炸火球演化特征及火球表... 详细信息

作为一种高能量密度炸药,温压炸药的爆炸毁伤效应及毁伤机理有别于传统炸药。结合敞开空间温压炸药爆炸冲击波及热效应试验,研究温压炸药爆炸冲击波特征及传播规律,采用高速摄像技术和光纤多谱线测温技术分析爆炸火球演化特征及火球表面温度变化规律。为研究温压炸药爆炸荷载对钢筋混凝土结构的毁伤效应,针对两种典型钢筋混凝土梁开展不同比例爆距下的爆炸试验,阐明两种钢筋混凝土梁在不同药量、不同爆距下的破坏特征和毁伤规律。研究结果表明:相比TNT炸药,温压炸药爆炸冲击波具有超压峰值大、正压作用时间长及峰值衰减缓慢的特点,温压炸药爆炸最高温度达到2400 K,超过1000 K的高温持续时间超过160 ms,高冲量爆炸冲击及持续高温作用导致钢筋混凝土结构受到更大程度的毁伤破坏。结合药量对毁伤规律的影响,提出钢筋混凝土梁在温压炸药近区(0.20~0.75 m)爆炸荷载条件下基于比例爆距和药量的毁伤判据。

关键词：温压炸药钢筋混凝土梁破坏特征毁伤判据

微沟槽织构设计对PDMS表面黏-滑摩擦学行为的影响

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摩擦学学报（中英文） 2024年第1期44卷 70-77页

作者：施文斌肖汉崔坤杰王涛时礼平吴玉国李蒙安徽工业大学机械工程学院安徽马鞍山243002 安徽工业大学芜湖技术创新研究院安徽芜湖241002

“黏-滑”现象是软材料表面摩擦学行为典型的特征,易诱发机械系统的振动与噪音等问题.本文中采用激光加工技术在PDMS(Polydimethylsiloxane,聚二甲基硅氧烷)表面加工了沟槽状织构阵列,研究不同参数织构设计对软材料表面“黏-滑”摩擦行... 详细信息

“黏-滑”现象是软材料表面摩擦学行为典型的特征,易诱发机械系统的振动与噪音等问题.本文中采用激光加工技术在PDMS(Polydimethylsiloxane,聚二甲基硅氧烷)表面加工了沟槽状织构阵列,研究不同参数织构设计对软材料表面“黏-滑”摩擦行为的影响.结果表明沟槽织构可以有效抑制软材料表面“黏-滑”行为,降低界面摩擦阻力,但沟槽的作用效能依赖于其倾斜角设计.此外,界面滑动速度和沟槽织构宽度也是影响表面摩擦学行为的主要因素.

关键词： “黏-滑”行为软材料摩擦学黏弹性表面织构