检索结果-南通市图书馆

中国循环杂志 2016年第Z1期31卷 -页

作者： Xiaqiu Tian yuejin yang State Key Laboratory of Cardiovascular Diseases FuwaiHospital NationalCenter for Cardiovascular Diseases Chinese Academy of MedicalSciences and Peking Union MedicalColege Beijing China

A high dynamic range pixel using lateral overflow integration capacitor and adaptive feedback structure in CMOS image sensors

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Optoelectronics Letters 2023年第12期19卷 721-726页

作者： yang yuejin XU Jiangtao MA Biao CHEN Quanmin NIE Kaiming School of Microelectronics Tianjin UniversityTianjin300072China Tianjin Key Laboratory of Imaging and Sensing Microelectronic Technology Tianjin UniversityTianjin300072China

This letter proposes a novel high dynamic range(HDR)pixel using lateral overflow integration capacitor(LOFIC)and adaptive feedback *** detailed analysis of the voltage feedback mechanism,the conversion gain(CG),full well capacity(FWC)and dynamic range(DR)performances of the feedback LOFIC pixel are analytically *** verification results reveal that the equivalent FWC of the feedback LOFIC pixel is 1.89 times of conventional LOFIC pixel,and the DR extension is 5.5 *** on 110 nm CMOS process,a 5.0µm pixel layout is presented,using 13.3 fF capacitance to achieve 83 ke-FWC and 102.8 dB DR,which are 44 ke-and 97.3 dB of conventional LOFIC pixel under the same design *** also demonstrates that the feedback LOFIC pixel can reduce the dependence of extended DR on capacitor area,and can be used as a reference for HDR pixels design.

关键词： HDR dynamic integration

Efficacy of Short-term Dual Antiplatelet Therapy after Implantation of Second-generation Drug-eluting Stents:A Meta-analysis and Systematic Review

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Sciences Journal 2017年第1期32卷 1-12页

作者： Peisen Huang Yuan Yu Xikun Han yuejin yang State Key Laboratory of Cardiovascular Disease Fuwai HospitalNational Center for Cardiovascular Diseases Chinese Academy of Medical Sciences & Peking Union Medical College Beijing 100037 China National Clinical Research Center of Cardiovascular Diseases Fuwai HospitalNational Center for Cardiovascular Diseases Chinese Academy of Medical Sciences & Peking Union Medical College Beijing 100037 China

Objective The benefit of short-term dual antiplatelet therapy(DAPT) following second-generation drug-eluting stents implantation has not been systematically evaluated. To bridge the knowledge gap,we did a meta-analysis to assess the efficacy of ≤6 months versus ≥12 months DAPT among patients with second-generation drug-eluting stents. Methods We searched online databases and identified randomized controlled trials that assess the clinical impact of short-term DAPT(≤6 months) published before March 3,2016. The efficacy endpoints included the incidence of all-cause death,myocardial infarction,cerebrovascular accidents,and definite or probable stent thrombosis. Safety endpoint defined as major bleeding was also evaluated and discussed. Results We included 5 trials that randomized 9473 participants(49.8%,short-term DAPT duration vs. 50.2%,standard duration). A total of 9445(99.7%) patients reported the efficacy endpoints,and the safety endpoint was available from 4 studies(n=8457). There was no significant difference in efficacy endpoints between short-term and standard DAPT duration(≥12 months) [risk ratio(RR) 0.96; 95% confidence intervals(CI),0.80-1.15]. Short-term DAPT duration did not significantly increase the individual risk of all-cause death,myocardial infarction,cerebrovascular accidents,or definite or probable stent thrombosis. Although short-term DAPT obviously reduced risk of major bleeding compared with standard DAPT(RR 0.53; 95% CI,0.29-0.96),significant publication bias was found when accessing the safety endpoint of the 4 studies(Egger's test,P=0.009). Conclusions The efficacy of short-term DAPT was comparable with that of standard duration *** less than 6 months may be appropriate for patients receiving second-generation drug-eluting stents implantation.

关键词： meta-analysis drug-eluting stents dual antiplatelet therapy percutaneous coronary intervention efficacy

The optimal timing for delayed percutaneous coronary intervention in patients with ST-segment elevation myocardial infarction presenting beyond 12 hours after symptoms onset

在线全文

学校读者我要写书评

暂无评论

中国循环杂志 2018年第S1期33卷 135-136页

作者： Qinghao Zhao Haiyan Xu Hongwei Yu yuejin yang Department of Cardiology National Center for Cardiovascular Dsi eases and Fuwai HospitalCAMS and PUMCBeijingChina

Objective To evaluate the impact of the timing of delayed PCI on the outcomes of patients with STEMI missing out on early reperfusion therapy within 12 h after symptom onset and ascertain the eligible time window to perform delayed *** Among 28,061 patients registered in China Acute Myocardial Infarction(CAMI)registry,a total of 3,048 stable patients with STEMI who did not underwent any early reperfusion therapy within 12 hours after symptom onset and received delayed PCI at recovery stage were finally enrolled.

关键词： PCI STEMI China Acute Myocardial Infarction

Safety and efficacy of a novel abluminal groove-filled biodegradable polymer sirolimus-eluting stent for the treatment of de novo coronary lesions:four-year results of the patient-level pooled analysis from TARGET I and TARGET II trials

在线全文

学校读者我要写书评

暂无评论

中国循环杂志 2016年第Z1期31卷 -页

作者： Changdong Guan Bo Xu yuejin yang Runlin Gao FuwaiHospital NationalCenter for Cardiovascular Diseases Chinese Academy of MedicalSciences and peking Union Medicalcolege Beijing China

Transradial versus transfemoral percutaneous coronary interventionin elderly patients： a systematic overview and meta-analysis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Medical Journal 2014年第6期127卷 1110-1117页

作者： He Peiyuan yang yuejin Hu Fenghuan Department of Cardiology Cardiovascular Institute and Fuwai Hospital National Center for Cardiovascular Diseases China Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100037 China

Background Transradial approach(TRA) percutaneous coronary intervention(PCI) has been wildly applied among unselected patients. However, only very few small studies have compared the outcomes between TRA and transfemoral approach(TFA) in elderly patients. We aimed to evaluate the efficacy and safety between TRA and TFA in elderly patients by a pooled *** Studies that met the inclusion and exclusion criteria were included. Statistical analysis was performed using the Review Manager 5.0.0 developed and maintained by the Cochrane Collaboration and a random-effects model was used to better account for the differences among the sub-studies. The primary endpoint was defined as short-term mortality, and other endpoints included major adverse cardiovascular events, major bleeding events, procedure success, vascular complications and hospital stay. Results Two thousand one hundred and eighty-eight patients from 11 studies were finally included. A non-significant trend toward a lower rate of short-term death was found in favor of TRA(odds ratio(OR): 0.56, 95% confidence interval(CI): 0.27–1.16). The incidence rates of vascular complications(OR 0.25, 95% CI: 0.14–0.46) and major bleeding events(OR: 0.31, 95% CI: 0.18–0.55) were greatly reduced by TRA compared with TFA. No significant difference was detected in the occurrence rate of major adverse cardiovascular events(OR: 0.77, 95% CI: 0.45–1.30), but the rate of procedure success was significantly improved by TRA(OR: 1.86, 95% CI: 1.18–2.94). In addition, the total hospital stay was also significantly reduced by *** TRA showed greater efficacy and safety compared with TFA in elderly patients. It should be recommend as routine practice for elderly patients undergoing PCI in TRA capable hospitals.

关键词： coronary artery disease angioplasty transradial approach meta analysis

Atorvastatin induces autophagy of mesenchymal stem cells underhypoxia and serum deprivation conditions by activating the mitogen-activated protein kinase/extracellular signal-regulatedkinase pathway

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2014年第6期127卷 1046-1051页

作者： Li Na Zhang Qian Qian Haiyan Jin Chen yang yuejin Gao Runlin State Key Laboratory of Cardiovascular Disease Fuwai Hospital National Center for Cardiovascular Disease Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100037 China

Background The survival ratio of implanted mesenchymal stem cells （MSCs） in the infarcted myocardium is *** is a complex self-eating process and can be utilized for cell survival. We have found that atorvastatin （ATV）can effectively activate autophagy to enhance MSCs survival during hypoxia and serum deprivation （H/SD）. The mitogen-activated protein kinase/extracellular signal-regulated kinase （MEK/ERK） pathway is a non-canonical autophagy *** hypothesized that the MEK/ERK pathway mediated ATV-induced autophagy of MSCs under H/SD.

关键词： mesenchymal stromal cells myocardial infarction autophagy hydroxymethylglutaryl-CoA reductase inhibitors signal transduction

Comparison of transradial and transfemoral percutaneous coronary intervention in women:a propensity score matching-based analysis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

中国循环杂志 2018年第S1期33卷 134-134页

作者： Yi Xu yuejin yang Department of Cardiology National Center for Cardiovascular Dsi eases and Fuwai HospitalCAMS and PUMCBeijingChina

Objective We conducted the present study in order to compare safety and efficacy of transradial intervention(TRI)and transfemoral intervention(TFI)in women undergoing percutaneous coronary intervention(PCI)in a large heart center in *** The study population consisted of a consecutive cohort of 5,067 women undergoing PCI in Fuwai Hospital,Beijing,China between 2006 and 2011(TRI:n=4,105,TFI:n=962).

关键词： transradial intervention transfemoral intervention percutaneous coronary intervention

Safety and efficacy of a novel abluminal groove-filled biodegradablepolymer sirolimus-eluting stent for the treatment of de novo coronarylesions： 12-month results from the TARGET II trial

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2014年第6期127卷 1027-1032页

作者： Xu Bo Zhao Yelin yang yuejin Zhang Ruiyan Li Hui Ma Changsheng Chen Shaoliang Department of Cardiology Fu Wai Hospital National Center for Cardiovascular Diseases Beijing 100037 China Department of Cardiology Ruijin Hospital Shanghai Jiao Tong University School of Medicine Shanghai 200025 China Department of Cardiology Daqing Oil Field General HospitalDaqing Heilongjiang 163114 China Department of Cardiology Affiliated Anzhen Hospital of Capital Medical University Beijing 100029 China Department of Cardiology Nanjing First Hospital Nanjing Medical University Nanjing Jiangsu 210006 China

Background In the TARGET I randomized controlled trial, the novel abluminal groove-filled biodegradable polymersirolimus-eluting stent FIREHAWK proved non-inferior to the everolimus-eluting stent in nine-month in-stent late loss insingle de novo coronary lesions. This study was aimed at evaluating clinical safety and effectiveness of FIREHAWK in amoderately complex population （including patients with small vessels, long lesions and multi-vessels）, and at validatingthe ability of the SYNTAX score （SS） to predict clinical outcomes in patients treated with this latest generation drug-elutingstent.

关键词：

One-year clinical safety and efficacy of drug eluting balloon in Chinese patients:a real-world singe center retrospective study

在线全文

学校读者我要写书评

暂无评论

中国循环杂志 2016年第Z1期31卷 -页

作者： Jie Qian Bo Xu yuejin yang Yongjian Wu Shubin Qiao Jilin Chen Haibo Liu Mengyue Yu Jue Chen Runlin Gao Fuwai Hospital NationalCenter for Cardiovascular Disease Chinese Academy of Medical Sciences and peking Union Medical colege Beijing China