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The History of Controlling and Treating Infectious Diseases in Ancient China

Current Medical Science 2024年第1期44卷 64-70页

作者： Cui-ling LIU tao ZHOU Liang-bin CHENG David FISHER Khrystyna PRONYUK Erkin MUSABAEV Yi-ping DANG Lei ZHAO Department of Infectious Diseases Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Department of Gastroenterology and Hepatology Huanggang Hospital of Traditional Chinese MedicineHubei University of Chinese MedicineHuanggang 438000China Clinical College of Traditional Chinese Medicine Hubei University of Chinese MedicineWuhan 430065China Department of Liver Diseases Hubei Hospital of Traditional Chinese MedicineWuhan 430061China Department of Medical Biosciences Faculty of Natural SciencesUniversity of the Western CapeBellvilleCape Town 7535South Africa Department of Infectious Diseases Bogomolets National Medical UniversityKyiv 02132Ukraine The Research Institute of Virology Ministry of HealthTashkent 100122Uzbekistan Department of Vascular Surgery Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China

Infectious diseases are the common enemies of *** the course of historical development,they persistently threaten human health and *** today,despite the developments in medical science,we cannot escape the fear and suffering caused by infectious *** in ancient or modern times,the source of infection,route of transmission,and a susceptible population are the three key conditions for the prevalence and spread of infectious *** factors closely related to these three conditions can affect the prevalence of infectious *** is one of the cradles of world *** ancient people accumulated a great deal of experience and lessons in the long struggle against infectious *** the face of the current threat posed by widespread infectious disease,it is imperative to review and summarize ancient Chinese ideas and health policies on epidemic prevention and control to inspire contemporary efforts in the prevention and control of infectious *** combination of prevention-oriented epidemic prevention ideology and traditional medicine provides valuable insights,especially for impoverished and medically underserved regions.

关键词： infectious diseases Chinese medicine public health historical review

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Mechanical characteristics and reservoir stimulation mechanisms of the Gulong shale oil reservoirs, the northern Songliao Basin

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Petroleum Science 2024年第3期21卷 2023-2036页

作者： Si-Wei Meng Jia-Ping tao Tian-Jiao Li Dong-Xu Li Su-ling Wang Liu Yang Xin Liu Li-Hao Liang He Liu PetroChina Research Institute of Petroleum Exploration Development Beijing100083China National Key Laboratory of Continental Shale Oil Daqing 163002HeilongjiangChina Dalian University of Technology Dalian116024LiaoningChina PetroChina Daqing Oilfield Co.Ltd. Daqing163002HeilongjiangChina Northeast Petroleum University Daqing163002HeilongjiangChina China University of Mining and Technology(Beijing) Beijing100083China

Shale oil of the Qingshankou Formation of the Gulong Sag,the northern Songliao Basin,represents the first attempt at large-scale development of pure-shale-type shale oil in *** integrating the multiscale refined reservoir characterization with macro-micro-scale mechanical testing,it is clarified that the Gulong shale is characterized by high clay mineral content,high rock plasticity,highly-developed bedding,and prominent mechanical anisotropy.A three-dimensional(3D)fracture propagation model of hydraulic fracturing was built for the Gulong shale,which fully captures the hydraulic fracture distribution pattern affected by the high bedding density,in-situ stress,and fracturing treatment *** research showed that due to influences of bedding,hydraulic fracturing in the Gulong shale forms a complex fracture morphology featuring the main fracture with multiple perpendicular branches that have different lengths(like the outdoor directional TV antenna);however,the vertical propagation of fractures is inhibited,and the fracture height is commonly less than 10 *** limited stimulated reservoir volume(SRV)is the main problem facing the fracturing stimulation of the Gulong shale *** density has vital effects on fracture morphology,so case-specific fracturing designs shall be developed for shale intervals with different bedding development *** reservoirs with welldeveloped bedding,it is suggested to properly increase the perforation cluster spacing and raise the volume and proportions of viscous fluids of the pad,so as to effectively promote vertical fracture propagation and improve reservoir stimulation *** study integrates multi-scale fine reservoir characterization and macro-micro-scale mechanical testing,as well as the construction and numerical simulation of hydraulic fracturing models for high-density layered shale reservoirs,providing a new approach and methodological framework for the fracturing research of high-density layer

关键词： Shale oil Hydraulic fracturing High bedding density Fracture propagation model

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Efficient removal of tetracycline hydrochloride through novel Fe/BiOBr/Bi_(2)WO_(6) photocatalyst prepared by dual-strategy under visible-light irradiation

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Journal of Environmental Sciences 2024年第4期138卷 46-61页

作者： Guanlong Yu Kai Yang Yi Yang Yifu Li Qifang Sun Peiyuan Li Wenming Wang Fengming Song tao ling Xuejun Peng Zhi Yu Shiquan Sun School of Hydraulic and Environmental Engineering Changsha University of Science&TechnologyChangsha 410114China Key Laboratory of Dongting Lake Aquatic Eco-Environmental Control and Restoration of Hunan Province Changsha 410114China Hunan Pilot Yanghu Reclaimed Water Co. Ltd.Changsha 410208China China Railway Wuju Group the First Engineering Co. Ltd.Changsha 410117China

It is important to investigate whether combining two modification strategies has a synergistic effect on the activity of *** this manuscript,Fe-doped BiOBr/Bi_(2)WO_(6) heterojunctions were synthesized by a one-pot solvothermal method,and excellent photocatalytic performance was obtained for the degradation of tetracycline hydrochloride(TCH)in water without the addition of *** experiments and characterization,the synergistic effect between Fe ion doping and the BiOBr/Bi_(2)WO_(6) heterojunction was *** Fe/BiOBr/Bi_(2)WO_(6) composite photocatalyst had a beneficial void structure,enhanced visible light response,and could inhibit the recombination of photogenerated support well,which improved the photocatalytic *** presented experiments demonstrate that Fe/BiOBr/Bi_(2)WO_(6) removes 97% of TCH from aqueous solution,while pure BiOBr and Bi_(2)WO_(6) only remove 56% and 65% of TCH,***,the separation and transfer mechanisms of photoexcited carriers were determined in conjunction with the experimental *** study provides a new direction for the design of efficient photocatalysts through the use of a dual co-modification strategy.

关键词： BiOBr/Bi_(2)WO_(6) Fe-doping Dual strategy Tetracycline hydrochloride Photodegradation

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Energy band modulation of N-doped rutile/anatase TiO_(2) photoanode promoting charge separation toward prominent photoelectrochemical performance

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Rare Metals 2024年第8期43卷 3784-3797页

作者： Juan Gao Shi-Xuan Wang Jia-Le Deng Ping-Ping Wei Fu-Zhang Chen ling-Cheng Zheng yue-Qin Wang Yang Li Yin Liu Gang He School of Mechanics and Photoelectric Physics Anhui University of Science and TechnologyHuainan 232001China School of Materials Science and Engineering Anhui UniversityHefei230039China Tianneng Battery(Wuhu)Co. Ltd.Wuhu 241000China School of Materials Science and Engineering Anhui University of Science and TechnologyHuainan 232001China

To solve the problem of high photogenerated carrier recombination rate and low photoelectric conversion efficiency of TiO_(2)-based materials,a simple N-doped anatase/rutile TiO_(2) heterophase nanorod film was designed by a low-temperature hydrothermal method in this *** enhanced separation and transport of photogenerated charges were facilitated by the smaller contact barrier and appropriate band matching between anatase TiO_(2)nanoparticles and rutile TiO_(2) *** introduction of N doping in anatase TiO_(2) resulted in an upward shift of the valence band and a narrowing of the band gap,consequently enhancing the efficiency of visible light *** combination of the heterophase junction and N-doping exhibited a synergistic effect,effectively suppressing the recombination of photogenerated charges and enhancing the photoelectric conversion efficiency of the *** AM 1.5G irradiation,the photocurrent density(J)of the A-TO(N)@R-TONR photoanode reached2.19 mA·cm^(-2)(V_(RHE,1.23 eV)).Additionally,the incident photon-electron conversion efficiency(IPCE)and the charge injection efficiency(η)reached 81.4%and 51.6%at320 ***,the J,IPCE,andηvalues of the A-TO(N)@R-TONR photoanode were 2.96,2.1 and 3.2times those of pure R-TONR photoanode,*** work presents a rational strategy for designing efficient TiO_(2)-based photoanodes.

关键词： TiO_(2) Heterophase junction Photoanode

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Dynamic Treatment Strategy of Chinese Medicine for Metastatic Colorectal Cancer Based on Machine Learning Algorithm

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Chinese Journal of Integrative Medicine 2024年第11期30卷 993-1000页

作者： XU Yu-ying LI Qiu-yan YI Dan-hui CHEN yue ZHAI Jia-wei ZHANG Tong SUN ling-yun YANG Yu-fei Department of Oncology Xiyuan Hospital China Academy of Chinese Medical Sciences School of Statistics Renmin University of China Graduate School Beijing University of Chinese Medicine

Objective: To establish the dynamic treatment strategy of Chinese medicine(CM) for metastatic colorectal cancer(m CRC) by machine learning algorithm, in order to provide a reference for the selection of CM treatment strategies for m CRC. Methods: From the outpatient cases of m CRC in the Department of Oncology at Xiyuan Hospital, China Academy of Chinese Medical Sciences, 197 cases that met the inclusion criteria were screened. According to different CM intervention strategies, the patients were divided into 3 groups: CM treatment alone, equal emphasis on Chinese and Western medicine treatment(CM combined with local treatment of tumors, oral chemotherapy, or targeted drugs), and CM assisted Western medicine treatment(CM combined with intravenous regimen of Western medicine). The survival time of patients undergoing CM intervention was taken as the final evaluation index. Factors affecting the choice of CM intervention scheme were screened as decision variables. The dynamic CM intervention and treatment strategy for m CRC was explored based on the cost-sensitive classification learning algorithm for survival(CSCLSurv). Patients' survival was estimated using the Kaplan-Meier method, and the survival time of patients who received the model-recommended treatment plan were compared with those who received actual treatment plan. Results: Using the survival time of patients undergoing CM intervention as the evaluation index, a dynamic CM intervention therapy strategy for m CRC was established based on *** CM intervention strategies for m CRC can be selected according to dynamic decision variables, such as gender, age, Eastern Cooperative Oncology Group score, tumor site, metastatic site, genotyping, and the stage of Western medicine treatment at the patient's first visit. The median survival time of patients who received the modelrecommended treatment plan was 35 months, while those who receive the actual treatment plan was 26.0 months(P=0.06). Conclusions:

关键词： Chinese medicine cost sensitive classification learning for survival dynamic treatment strategy metastatic colorectal cancer

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Eigenvalues for the Clamped Plate Problem of L_(ν)^(2) Operator on Complete Riemannian Manifolds

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Acta Mathematica Sinica,English Series 2024年第9期40卷 2223-2243页

作者： ling Zhong ZENG Jiangxi Provincial Center for Applied Mathematics&School of Mathematics and Statistics Jiangxi Normal UniversityNanchang 330022P.R.China

L_(ν) operator is an important extrinsic differential operator of divergence type and has profound geometric *** this paper,we consider the clamped plate problem of L_(ν)^(2)operator on a bounded domain of the complete Riemannian manifolds.A general formula of eigenvalues of L_(ν)^(2) operator is *** this general formula,we obtain some estimates for the eigenvalues with higher order on the complete Riemannian *** several fascinating applications,we discuss this eigenvalue problem on the complete translating solitons,minimal submanifolds on the Euclidean space,submanifolds on the unit sphere and projective *** particular,we get a universal inequality with respect to the L_(II) operator on the translating ***,it is very difficult to get universal inequalities for weighted Laplacian and even Laplacian on the complete Riemannian ***,this work can be viewed as a new contribution to universal estimate.

关键词： Mean curvature flows L_(ν)^(2)operator clamped plate problem eigenvalues Riemannian manifolds translating solitons

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Enhancing layered perovskite ferrites with ultra-high-density nanoparticles via cobalt doping for ceramic fuel cell anode

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Journal of Energy Chemistry 2024年第9期96卷 39-48页

作者： Shuo Zhai Rubao Zhao Hailong Liao ling Fu Senran Hao Junyu Cai Yifan Wu Jian Wang Yunhong Jiang Jie Xiao tao Liu Heping Xie State Key Laboratory of Intelligent Construction and Healthy Operation and Maintenance of Deep Underground Engineering Shenzhen University&Sichuan UniversityShenzhen 518060GuangdongChina National and Local Joint Engineering Research Center for Lithium-ion Batteries and Materials Preparation Technology Key Laboratory of Advanced Battery Materials of Yunnan ProvinceFaculty of Metallurgical and Energy EngineeringKunming University of Science and TechnologyKunming 650093YunnanChina School of Energy and Environment City University of Hong KongKowloon 999077Hong KongChina

Nanoparticles anchored on the perovskite surface have gained considerable attention for their wide-ranging applications in heterogeneous catalysis and energy conversion due to their robust and integrated structural ***,we employ controlled Co doping to effectively enhance the nanoparticle exsolution process in layered perovskite ferrites *** alloy nanoparticles with ultra-high-density are exsolved on the(PrBa)_(0.95)(Fe_(0.8)Co_(0.1)Nb_(0.1))2O_(5+δ)(PBFCN_(0.1))surface under reducing atmosphere,providing significant amounts of reaction sites and good durability for hydrocarbon *** a reducing atmosphere,cobalt facilitates the reduction of iron cations within PBFCN_(0.1),leading to the formation of CoFe alloy *** formation is accompanied by a cation exchange process,wherein,with the increase in temperature,partial cobalt ions are substituted by ***,Co doping significantly enhance the electrical conductivity due to the stronger covalency of the Cosingle bondO bond compared with Fesingle bondO bond.A single cell with the configuration of PBFCN_(0.1)-Sm_(0.2)Ce_(0.8)O_(1.9)(SDC)|SDC|Ba_(0.5)Sr_(0.5)Co_(0.8)Fe_(0.2)O_(3−δ)(BSCF)-SDC achieves an extremely low polarization resistance of 0.0163Ωcm^(2)and a high peak power density of 740 mW cm^(−2)at 800℃.The cell also shows stable operation for 120 h in H_(2)with a constant current density of 285 mA cm^(−2).Furthermore,employing wet C_(2)H_(6)as fuel,the cell demonstrates remarkable performance,achieving peak power densities of 455 mW cm^(−2)at 800℃and 320 mW cm^(−2)at 750℃,marking improvements of 36%and 70%over the cell with(PrBa)_(0.95)(Fe_(0.9)Nb_(0.1))_(2)O_(5+δ)(PBFN)-SDC at these respective *** discovery emphasizes how temperature influences alloy nanoparticles exsolution within doped layered perovskite ferrites materials,paving the way for the development of high-performance ceramic fuel cell anodes.

关键词： Solid oxide fuel cell Anode Ethane fuel Nanoparticle Exsolution Layered perovskite Ferrites

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Insights into the history and tendency of glycosylation and digestive system tumor:A bibliometric-based visual analysis

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World Journal of Gastrointestinal Oncology 2024年第3期16卷 1059-1075页

作者： Jie Jiang Zai Luo Ren-Chao Zhang yue-ling Wang Jun Zhang Ming-Yu Duan Zheng-Jun Qiu Chen Huang Department of Gastrointestinal Surgery Shanghai General HospitalShanghai Jiao Tong University School of MedicineShanghai 200080China Jiangnan University Wuxi School of Medicine Wuxi 214122Jiangsu ProvinceChina Department of Education Shanghai General HospitalShanghai Jiao Tong University School of MedicineShanghai 200080China

BACKGROUND Glycosylation,a commonly occurring post-translational modification,is highly expressed in several tumors,specifically in those of the digestive system,and plays a role in various cellular pathophysiological *** the importance and detection methods of glycosylation in digestive system tumors have garnered increasing attention in recent years,bibliometric analysis of this field remains *** present study aims to identify the developmental trends and research hotspots of glycosylation in digestive system *** To find and identify the developmental trends and research hotspots of glycosylation in digestive system *** We obtained relevant literature from the Web of Science Core Collection and employed VOSviewer 1.6.19 and CiteSpace(version 6.1.R6)to perform bibliometric *** A total of 2042 documents spanning from 1978 to the present were analyzed,with the research process divided into three phases:the period of obscurity(1978-1990),continuous development period(1991-2006),and the rapid outbreak period(2007-2023).These documents were authored by researchers from 66 countries or regions,with the United States and China leading in terms of publication *** Celso A had the highest number of publications,while Pinho SS was the most cited ***-occurrence analysis revealed the most popular keywords in this field are glycosylation,expression,cancer,colorectal cancer,and pancreatic ***,the Journal of Proteome Research was the most prolific journal in terms of publications,while the Journal of Biological Chemistry had the most *** The bibliometric analysis shows current research focus is primarily on basic research in this ***,future research should aim to utilize glycosylation as a target for treating tumor patients.

关键词： Glycosylation Cancer Digestive system Bibliometric analysis CiteSpace VOS viewer

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Feasibility of Synchronously Straightening Working Line of Adjacent Open-cast Mines

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Asian Agricultural Research 2024年第7期16卷 28-32页

作者： ling LIU tao DONG CCTEG Shenyang Engineering Company Shenyang 110015China

Taking Heidaigou Open-cast Mine and Haerwusu Open-cast Mine in Zhungeer mining area as the research objects,this paper deeply analyzes the current mining status of the two *** on the existing working line length,mining technology,transportation system,equipment configuration,transportation access and many other factors,it systematically discusses the feasibility of straightening the working line of adjacent open-cast *** in-depth theoretical analysis,it establishes the mathematical model of impact indicators and cost calculation,and it is concluded that the work line straightening can be technically ***,from the perspective of economic benefits,straightening the working line does not show obvious advantages.

关键词： Adjacent open-cast mines Tracing the mining Working line straightening Advancing direction

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Bibliometrics analysis based on the Web of Science:Current trends and perspective of gastric organoid during 2010-2023

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World Journal of Gastroenterology 2024年第8期30卷 969-983页

作者： Kai-Lin Jiang yue-Bo Jia Xue-Jiao Liu Qing-ling Jia Li-Kun Guo Xiang-Xiang Wang Ke-Ming Yang Chen-Heng Wu Bei-Bei Liang Jiang-Hong ling Department of Gastroenterology Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese MedicineShanghai 200021China Laboratory of Cancer Biology University of OxfordOxford OX37DQUnited Kingdom School of Traditional Chinese Medicine Shanghai University of Chinese MedicineShanghai 200021China Shanghai Key Laboratory of Molecular Imaging Shanghai University of Medicine and Health SciencesShanghai 201318China

BACKGROUND Three-dimensional organoid culture systems have been established as a robust tool for elucidating mechanisms and performing drug efficacy *** use of gastric organoid models holds significant promise for advancing personalized medicine ***,a comprehensive bibliometric review of this burgeoning field has not yet been *** To analyze and understand the development,impact,and direction of gastric organoid research using bibliometric methods using data from the Web of Science Core Collection(WoSCC)*** This analysis encompassed literature pertaining to gastric organoids published between 2010 and 2023,as indexed in the *** and VOSviewer were used to depict network maps illustrating collaborations among authors,institutions and keywords related to gastric ***,co-citation,and burst analysis methodologies were applied to assess the impact and progress of *** A total of 656 relevant studies were *** majority of research was published in gastroenterology-focused ***,Yana Zavros,Hans Clevers,James M Wells,Sina Bartfeld,and Chen Zheng were the 5 most productive authors,while Hans Clevers,Huch Meritxell,Johan H van Es,Marc Van de Wetering,and Sato Toshiro were the foremost influential scientists in this *** from the University Medical Center Utrecht,Netherlands Institute for Developmental Biology(Utrecht),and University of Cincinnati(Cincinnati,OH,United States)made the most significant ***,gastric organoids are used mainly in studies investigating gastric cancer(GC),Helicobacter pylori-infective gastritis,with a focus on the mechanisms of GC,and drug screening *** Key focus areas of research using gastric organoids include unraveling disease mechanisms and enhancing drug screening *** contributions from renowned academic institutions highlight this field’s dynamic growth.

关键词： Gastric organoid Gastric disease Bibliometrics analysis Gastric cancer Gastritis

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